• The Korean Journal of Physiology
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• 제30권1호
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• pp.117-124
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• 1996

This study evaluated the hypothesis that motoneuron collaterals modulate the excitability of ventral spinocerebellar tract neurons. In acute cats, 128 ventral cerebellar tract cells were studied extracellularly to determine the effects of ventral root stimuli. The majority of the cells responded to ventral root stimulation with either short or long latency increases in spike discharge. In many cells with sufficient spontaneous activity ventral root stimulation also evoked a long lasting reduction in activity. In preparations with the dorsal root ganglion removed VSCT neurons had similar response properties. In some cells contralateral ventral root stimulation also evoked excitatory responses. These findings indicate the VSCT can provide the cerebellum with information regarding activity in the final output neurons of the motor system, the alpha motoneurons.

• Biomolecules & Therapeutics
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• 제29권3호
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• pp.282-289
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• 2021

A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), caused a worldwide pandemic. Our aim in this study is to produce new fusion inhibitors against SARS-CoV-2, which can be the basis for developing new antiviral drugs. The fusion core comprising the heptad repeat domains (HR1 and HR2) of SARS-CoV-2 spike (S) were used to design the peptides. A total of twelve peptides were generated, comprising a short or truncated 24-mer (peptide #1), a long 36-mer peptide (peptide #2), and ten peptide #2 analogs. In contrast to SARS-CoV, SARS-CoV-2 S-mediated cell-cell fusion cannot be inhibited with a minimal length, 24-mer peptide. Peptide #2 demonstrated potent inhibition of SARS-CoV-2 S-mediated cell-cell fusion at 1 µM concentration. Three peptide #2 analogs showed IC50 values in the low micromolar range (4.7-9.8 µM). Peptide #2 inhibited the SARS-CoV-2 pseudovirus assay at IC50=1.49 µM. Given their potent inhibition of viral activity and safety and lack of cytotoxicity, these peptides provide an attractive avenue for the development of new prophylactic and therapeutic agents against SARS-CoV-2.

• 한국작물학회지
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• 제30권3호
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• pp.314-319
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• 1985

장일과 단일조건에서 보리 7개 품종의 엽수, 유수발육, 유수장, 영화수 및 지엽전개일수의 차이를 검토하고자 실험한 결과를 요약하면 다음과 같다. 1. 장일조건에서 품종간 주간엽수의 차이는 거의 없었으나 단일조건에서는 조숙종은 6∼7엽, 만숙종은 9∼10 엽이었다. 2. 단일조건에서 조숙인 조강보리, 오월보리는 유수의 발육이 이식 24일경에 X기에, 만숙인 CI 15446은 32일경에 X기에 도달하였다. 3. 유수장의 변화는 장일보다 단일조건에서 커서 조숙종은 이식 30일에 만열종은 51일경에 최대 신장을 보였다. 4. 단일에서 일수입수가 2배정도 많았으며 감광성이 적은 품종은 조강보리, 오월보리 등이었고 큰 품종은 새올보리 ＞CI 15446 ＞항미 순위이었다. 5. 본 실험결과로 조숙종은 만숙종에 비해 단일조건에서 주간엽수의 변이가 적고, 주간의 유수발육 및 유수장신장의 지연, 출수기의 지연이 적었다.

• 한국유체기계학회 논문집
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• 제6권4호
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• pp.58-65
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• 2003

Stall inception means the phenomena of rotating stall initiation. The initiation mechanism of rotating stall, the existence of stall precursor, the behavior of stall precursor, stall warning scheme and control scheme are the main interests in stall inception research. Compared to the studies on rotating stall which has long history, the stall inception has been studied for about recent 20 years. After the first discovery of stall precursor in about 20 years ago, many studies were reported on stall inception phenomena. The inception pattern of 'mode' and 'spike' were found, and some of its characteristics are known. And now the stall inception has become one of the fascinating fields in turbomachinery. The development stall control scheme which apply the reliable stall warning scheme will play a great role in future compressor and aeroengine. This paper reviews the results and analysis methods on stall inception studies.

• Transactions on Electrical and Electronic Materials
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• 제6권1호
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• pp.1-5
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• 2005

Continued scaling of MOS devices requires the formation of the ultra shallow and very heavily doped junction. The simulation and experiment results show that the degradation of pMOS performance in logic and SRAM pMOS devices due to the excessive diffusion of the tail and a large amount of dose loss in the extension region. This problem comes from the high-temperature long-time deposition process for forming the spacer and the presence of fluorine which diffuses quickly to the $Si/SiO_{2}$ interface with boron pairing. We have studied the method to improve the pMOS performance that includes the low-energy boron implantation, spike annealing and device structure design using TCAD simulation.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.875-880
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• 2003

Stall inception means the phenomena of rotating stall initiation. The initiation mechanism of rotating stall, the existence of stall precursor, the behavior of stall precursor, stall warning scheme and control scheme are the main interests in stall inception research. Compared to the studies on rotating stall which has long history, the stall inception has been studied for about recent 20 years. After the first discovery of stall precursor in about 20 years ago, many studies were reported on stall inception phenomena. The inception pattern of "mode" and "spike" were found, and some of its characteristics are known. And now the stall inception has become one of the fascinating fields in turbomachinery. This paper reviews the results and analysis methods on stall inception studies.

• 터널과지하공간
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• 제5권1호
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• pp.70-76
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• 1995

Two types of deformations can occur on the cable during the monitoring of the rock displacement by the time domain reflectometry. One is the impedance model for tensile deformation, and the other is the capacitance model for the shear deformation. The former gives a response signal with a gradual change in the amplitude of the reflected voltage, meanwhile the latter produces a signal with a blunted spike. The resolution of the TDR can be improved to 0.125% using calibration crimps on the cable of 60 meters long. It is recommended that the diameter of the cable should be 18 mm at least in order to induce a better reflected pulse without any open-circuit. The actual TDR technique cannot characterize the type and the magnitude of rock displacement quantitatively. Systematic investigation of the TDR parameters, such as the exact of cable diameter, cable length, number of crimps, combination of shearing and extension, and environment of the TDR equipment, will be able to improve the resolution to 0.01 mm.

• 대한전기학회논문지:시스템및제어부문D
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• 제52권3호
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• pp.163-172
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• 2003

A stereo matching has been an important tool for the reconstruction of 3D terrain. The current state of stereo matching technology has reached the level where a very elaborate DEM(Digital Elevation Map) can be obtained. However, there still exist many factors causing DEM error in stereo matching. This paper propose a new method to reduce the error caused by the lack of significant features in the correlation window The proposed algorithm keeps the correlation window as small as possible, as long as there is a significant feature in the window. Experimental results indicate that the proposed method increases the DEM accuracy by $72.65\%$ in the plain area and $41.96\%$ in the mountain area over the conventional scheme. Comparisons with Kanade's result show that the proposed method eliminates spike type of errors more efficiently than Kanade's adaptive window technique and produces reliable DEM.

• Journal of Plant Biotechnology
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• 제29권4호
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• pp.217-222
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• 2002

재래종 쌀보리 들은 추파형이며 내한성이 약하고 장간이면서 밀수, 장망으로 출수가 늦은 품종이 많았다. 그러나 파성, 내한성, 출수기, 간장, 수장의 변이가 컸으며, 내한성이 강한 품종, uzu 유전자, 찰성, 자색종피 등 다양한 유용 돌연변이를 보였다. 재래종들의 유연관계를 형태적 특성과 RAPD분석 결과, 112품종 모두 다른 품종으로 밝혀졌으며, 재래종 쌀보리와 겉보리의 유전적 특성을 비교한 결과, 일양성이 인정되어 쌀보리 품종들이 겉보리 재래종으로부터 돌연변이 되었던 것으로 추정할 수 있었다.

• 한국식품조리과학회지
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• 제31권5호
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• pp.551-556
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• 2015

Iksan370 is a long-spike wheat developed by the Rural Development Administration yielding excellent features components such as cold resistance, disease resistance, and viviparous germination. The physicochemical and material properties of the raw wheat and milled flour of Iksan370 were analyzed to derive its appropriate uses. The raw wheat of Iksan370 showed high contents of ash and proteins at 1.71% and 13.7%, respectively. Its test weight of 763.0 g/L was similar to those of other varieties and its 1,000 kernel weight was high at 45.38 g. The milled flour of Iksan370 had an ash content of 0.45%, which corresponds with a class 1 flour, and its protein content is 12.18%, corresponding with strong flour. The damaged starch was 5.41%, which was lower than that of other varieties. The average grain size was $70.67{\mu}m$ and the grain distribution was at the level of a typical hard wheat. In the farinogram, the water absorption was 58.63%, which corresponded to the level of medium flour. The development time was 7.00 minutes, which was significantly lower than those of Jokyung and Keumkang. The degree of softening was 67.00 BU, similar to those of Yunbaek and Baekjoong. Among the physico-chemical characteristics, the high protein content and typical hard wheat grain distribution of Iksan370 were similar to those of strong wheat, usually used for bread making. However, in the farinogram, the dough development time was short and the degree of softening was high. As a result, Iksan370 was expected to have poor breadmaking properties and a small volume of the final bread product due to insufficient dough durability. On the other hand, Iksan370 showed the highest maximum gelatinization viscosity at 864.00 BU. Therefore, Iksan370 is expected to show glutinous texture when used for noodles and its flour appears to be appropriate for frying powders as well.