• Journal of the Computational Structural Engineering Institute of Korea
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• v.35 no.5
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• pp.249-257
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• 2022

This paper presents an improved computational framework for the direct-solution-based finite element tearing and interconnecting (FETI) algorithm. The FETI-local algorithm is further improved herein, and localized Lagrange multipliers are used to define the interface among its subdomains. Selective inverse entry computation, using a property of the Boolean matrix, is employed for the computation of the subdomain interface stiffness and load, in which the original FETI-local algorithm requires a full matrix inverse computation of a high computational cost. In the global interface computation step, the original serial computation is replaced by a parallel multi-frontal method. The performance of the improved FETI-local algorithm was evaluated using a numerical example with 64 million degrees of freedom (DOFs). The computational time was reduced by up to 97.8% compared to that of the original algorithm. In addition, further stable and improved scalability was obtained in terms of a speed-up indicator. Furthermore, a performance comparison was conducted to evaluate the differences between the proposed algorithm and commercial software ANSYS using a large-scale computation with 432 million DOFs. Although ANSYS is superior in terms of computational time, the proposed algorithm has an advantage in terms of the speed-up increase per processor increase.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38C no.7
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• pp.630-642
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• 2013

To transmit vital signal stream of mobile patients remotely, it requires mobility of patient and watcher, sensing function of patient's abnormal symptom and self-organizing service binding of related computing resources. In the existing relative researches, the vital signal stream is transmitted as a centralized approach which exposure the single point of failure itself and incur data traffic to central server although it is localized service. Self-organizing middleware platform based on heterogenous overlay network is a middleware platform which can transmit real-time data from sensor device(including vital signal measure devices) to Smartphone, TV, PC and external system through overlay network applied self-organizing mechanism. It can transmit and save vital signal stream from sensor device autonomically without arbitration of management server and several receiving devices can simultaneously receive and display through interaction of nodes in real-time.

• Journal of Korean Society for Geospatial Information Science
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• v.18 no.3
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• pp.11-19
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• 2010

In recent years, Korea has witnessed an increase to natural disasters such as landslides due to localized sudden and intensive rainfalls. Thus there have been researches on surface displacements to detect and monitor displacements in the areas prone to landslides by using high-precision and density numerical elevation data from LiDAR, which is an advanced 3D measuring equipment. However, the commercial software to process large-capacity LiDAR data, is expensive and difficult to be applied to specialized tasks such as analysis of landslide. In addition, there are no measures for many users to easily access diverse spatial information related to landslides and put it to intuitive uses. Thus this study developed an application program to analyze landslides by processing time series LiDAR data and intuitively serve many users with information about the topography and landslides of given areas. It analyzed the current state of landslides in the subject region through case study and proposed that 3D-based landslide and topography information can be served intuitively.

• Microbiology and Biotechnology Letters
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• v.49 no.2
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• pp.148-156
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• 2021

Single-chain antibodies against epidermal growth factor receptor variant III (EGFRvIII) are potentially promising agents for developing antibody-based cancer treatment strategies. We described in our previous study the successful expression of an anti-EGFRvIII scFv antibody in Escherichia coli. However, we could also observe the formation of insoluble aggregates in the periplasmic space, limiting the production yield of the active product. In the present study, we investigated the mechanisms by which growth conditions could affect the expression of the soluble anti-EGFRvIII scFv antibody in small-scale E. coli NiCo21(DE3) cultures, attempting to maximize production. The secreted scFv molecules were purified using Ni-NTA magnetic beads and protein characterization was performed using SDS-PAGE and western blot analyses. We used the ImageJ software for protein quantification and determined the antigen-binding activity of the scFv antibody against the EGFRvIII protein. Our results showed that the highest percentage of soluble scFv expression could be achieved under culture conditions that combined low IPTG concentration (0.1 mM), low growth temperature (18℃), and large culture dish surface area. We found moderate-yield soluble scFv production in the culture medium after lactose-mediated induction, which was also beneficial for downstream protein processing. These findings were confirmed by conducting western blot analysis, indicating that the soluble, approximately 30-kDa scFv molecule was localized in the periplasm and the extracellular space. Moreover, the antigen-binding assay confirmed the scFv affinity against the EGFRvIII antigen. In conclusion, our study reveals that low-speed protein expression is preferable to obtain more soluble anti-EGFRvIII scFv protein in an E. coli expression system.

• Journal of the Korean Association of Geographic Information Studies
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• v.23 no.4
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• pp.234-252
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• 2020

This paper is to verify the effectiveness of 'Hybrid Disaster Management Strategy' that integrates 'RTM(Real-time Monitoring) based On-line' and 'UAV based Off-line' system. For landslide prone area where sensors were installed, the conventional way of risk management so far has entirely relied on RTM data collected from the field through the instrumentation devices. But it's not enough due to the limitation of'Pin-point sensor'which tend to provide with only the localized information where sensors have stayed fixed. It lacks, therefore, the whole picture to be grasped. In this paper, utilizing 'Digital Photogrammetry Software Pix4D', the possibility of inference for the deformation of ungauged area has been reviewed. For this purpose, actual measurement data from RTM were compared with the estimated value from 3D point cloud outcome by UAV, and the consequent results has shown very accurate in terms of RMSE.

• Journal of the Korean association of regional geographers
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• v.22 no.3
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• pp.499-514
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• 2016

Social enterprise is defined as a sort of companies that pursue both publicity and profitability. It is usual that their business activities and viability are dependent upon localized resources in terms of a labor market, raw material procurement and sales market. Also, the characteristics and viability of social enterprises based on local resources within the framework of social economy policy. The social economic policy in Korea is generally treated as means of local developments. This paper aims to examine the localness and socio-economic foundation of social enterprises which are located in the west of Gyeongnam province in Korea and to provide policy recommendations for promoting local resource-based social enterprises. The selection of the case study firms was chosen by considering various factors such as the viability of the firm, location of a company and the types of organization. The research result shows that most of local social enterprises had a viability and profitability to effectively utilize local resources. But it is claimed that the government policy for promoting local social enterprises reveals some limitations to promoting effectively local social enterprises. First, it is necessary to limit the qualification of applying to the government support program. Second, financial support should be changed from hardware-centered programs to software-centered programs such as training and education for human resource development and the business consulting. Finally, it is necessary for the government policy to focus on follow-up programs for firms which are no more capable of receiving the government financial support. For these firms, the government policy needs to focus on facilitating activities of cooperation between local universities and local social enterprise.

• Korean Journal of Remote Sensing
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• v.36 no.3
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• pp.475-486
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• 2020

Climate change scenarios are the basis of research to cope with climate change, and consist of large-scale spatio-temporal data. From the data point of view, one scenario has a large capacity of about 83 gigabytes or more, and the data format is semi-structured, making it difficult to utilize the data through means such as search, extraction, archiving and analysis. In this study, a tool for analyzing extreme climate events based on spatial information is developed to improve the usability of large-scale, multi-period climate change scenarios. In addition, a pilot analysis is conducted on the time and space in which the heavy rain thresholds that occurred in the past can occur in the future, by applying the developed tool to the RCP8.5 climate change scenario. As a result, the days with a cumulative rainfall of more than 587.6 mm over three days would account for about 76 days in the 2080s, and localized heavy rains would occur. The developed analysis tool was designed to facilitate the entire process from the initial setting through to deriving analysis results on a single platform, and enabled the results of the analysis to be implemented in various formats without using specific commercial software: web document format (HTML), image (PNG), climate change scenario (ESR), statistics (XLS). Therefore, the utilization of this analysis tool is considered to be useful for determining future prospects for climate change or vulnerability assessment, etc., and it is expected to be used to develop an analysis tool for climate change scenarios based on climate change reports to be presented in the future.

• Journal of Distribution Science
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• v.13 no.1
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• pp.27-33
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• 2015

Purpose - The ICT market in the EU is lagging behind that of the US; however, algorithm and software development within the EU have grown steadily, and they involve focusing on the creative cultural convergence conceptualized as part of Horizon 2020 and connecting neighboring markets in the EE and the Mediterranean region. It is essential to study the requirements to market the EU's creative ICT development in emerging industrial countries after examining its applicability in these countries. Research design, data, and methodology - This study deals with data pertaining to the EU's creative industry and competitive edge. The global cultural expansion of the EU facilitates a new concept involving not only low-cost IT products to enhance local cultural artifacts through R&D and the construction of efficient infrastructure services, but also information exchange with a realistic commercialization of the technology that can be applied for creative cultural localization. In the European industry, research on algorithms has been applied for the benefit of consumers. We investigated how the process is conducted in the EU. Results - Europe needs to adjust its economic structure to the local culture as part of IT distribution convergence. The convergence has been converted into a production algorithm with IT in the form of low-cost production. This is because there is an attempt to improve the quality of transport infrastructure, workforce availability, and the distribution of the distance to the local industries and consumers, using IT algorithms. Integrated into the manufacturing industry, based on the ICT infrastructure and solutions, smart localized regional clusters are formed with the help of grafting. Europe has own strategy to increase the number of hub-and-spoke cities. Europe is now becoming integrated, with an EPC system for regional cooperation rather than national competition in ICT technology. Europe has also been recognized in this study as changing the step-by-step paradigm for global competitiveness through new creative culture industries. Conclusions - As a result, there are several ways of converging with others through EU R&D intensity; therefore, the EU can be seen as successfully increasing marginal value, which is useful in developing a special industrial cluster or local cultural cities that create converged development by connecting people and objects with IT. In fact, when compared to the US, Europe has a strong culture and the car industries have a tendency to overshadow the IT industries with integration of services in IT distribution. Considering the rapid environmental changes, the convergence of IT services is likely to take place in Europe, similar to the pharmaceutical industry and the automotive industry. This requires a focus on human resources and automated systems management. The trend is to move away from low-wage industries, switched to key personnel centers of the local university-industry. EU emphasizes the creation of IT market demand in Europe involving local cultural convergence for marketing as the second step to strengthen the economic hub-and-spoke areas.

• Tunnel and Underground Space
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• v.31 no.6
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• pp.400-414
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• 2021

Under high-level radioactive waste repository conditions, bentonite as an engineered barrier material undergoes thermal, hydrological, mechanical, and chemical processes. We report the applications of X-ray Computed Tomography (CT) imaging technique on the characterization and analysis of bentonite over the past decade to provide a reference of the utilization of this technique and the recent research trends. This overview of the X-ray CT technique applications includes the characterization of the bentonite either in pellets or powder form. X-ray imaging has provided a means to extract grain information at the microscale and identify crack networks responsible for the pellets' heterogeneity. Regarding samples of pellets-powder mixtures under hydration, X-ray CT allowed the identification and monitoring of heterogeneous zones throughout the test. Some results showed how zones with pellets only swell faster compared to others composed of pellets and powder. Moreover, the behavior of fissures between grains and bentonite matrix was observed to change under drying and hydrating conditions, tending to close during the former and open during the latter. The development of specializing software has allowed obtaining strain fields from a sequence of images. In more recent works, X-ray CT technique has served to estimate the dry density, water content, and particle displacement at different testing times. Also, when temperature was added to the hydration process of a sample, CT technology offered a way to observe localized and global density changes over time.