• Korean Journal of Veterinary Research
• /
• v.45 no.1
• /
• pp.7-15
• /
• 2005

To elucidate the roles of phospho-IkB expression in the development and progression of EAE, we investigated the expression of phospho-IkB in the central nervous system (CNS) of rats during experimental autoimmune encephalomyelitis (EAE) using immunohistochemistry and Western blot analysis. In Western blot analysis, the increased expression of phospho-IkB went parallel to severity of EAE. The expression of phospho-IkB increased significantly at the peak stage of EAE followed by gradual decrease. Immunohistochemical studies showed that the phospho-IkB immunoreactivity was mainly expressed in inflammatory cells (macrophages, T cells) and glial cells (astrocytes, microglial cells) at the peak stage of EAE and disappeared at the recovery stage. These findings suggest that the phosphorylation of IkB is closely associated with autoimmune inflammation in the CNS and plays an important role in the initiation and progression of EAE.

• International Journal of Oral Biology
• /
• v.40 no.3
• /
• pp.127-133
• /
• 2015

The salivary gland undergoes complex process of growth and differentiation of the branching morphogenesis of ductal system during the prenatal and early postnatal periods which are regulated by various elements in the extracellular matrix. Extracellular matrix metalloproteinase inducer (EMMPRIN) is a cell adhesion molecule. In the present study, localization and expression of EMMPRIN in development and effects of chorda-lingual denervation and cyclosporine A (CsA) treatment on the EMMPRIN expression were investigated. Immunohistochemistry, RT-PCR and Western blot were used to determine expression level. Immunohistochemistry revealed that EMMPRIN was localized specifically in the cytoplasm of ductal cells, not acini of the submandibular gland all the postnatal periods. At prenatal day 18, when the formation of ducts was not definite, no immunoreactivity was observed. Both Western blot and RT-PCR analyses revealed that EMMPRIN expression was maintained up to postnatal day 7, decreased after postnatal day 10. The EMMPRIN expression was upregulated by the surgical denervation of the chorda-lingual nerve in the gland as well as by the CsA treatment. The present study suggests that EMMPRIN is a crucial molecule for maintaining physiological functions of the salivary gland.

• The Transactions of the Korean Institute of Electrical Engineers P
• /
• v.61 no.4
• /
• pp.180-185
• /
• 2012

Tidal power is one of new and renewable energy sources. The seawater is stored inside a tidal embankment built at the mouth of a river or bay, where tides ebb and flow. The water turbine-generators produce power by exploiting the gap in the water level between the water outside and inside the embankment. Tidal power plant is a large plant that is installed on the sea. And then, the facility's operations and a separate control system for monitoring and maintenance is required. However, this plant predictive control of building systems and technologies have been avoided the transfer of technology from advanced global companies. Accordingly, the control system for core technology development and localization is urgently needed. This paper presents modeling and simulation using by PSS/E about generator, governor, exciter, and power system stabilizer for control system in Sihwa tidal power plant to improve the efficiency and develope of core technology. And the dynamic characteristics of governor and exciter were analyzed.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2016.05a
• /
• pp.404-406
• /
• 2016

Due to the localization process of offshore drilling system, ensuring safety has emerged as an important. Therefore, step by stem safety analysis about each development process of offshore drilling system is becoming compulsory. Hazard and operability analysis is a method that was successfully used for system safety analysis in industries such as chemical plants. Through this hazard and operability analysis study, to conduct step by step safety analysis accorsing to process, the study conducted hazard and operability analysis in Lp mud system, an area of offshore drilling system.

• Proceedings of the KIEE Conference
• /
• 2000.07d
• /
• pp.2784-2786
• /
• 2000

Mobile robots include control modules for autonomous obstacle avoidance and navigation. They are range modules to detect and avoid obstacles. motor control modules to operate two wheels. and encoder modules for localization. There is needed an appropriate controller for each modules. In this paper. a control system. including 18 channels for Sonar sensors. 4 channels for PWM modules. and 4 channels for encoder modules. is proposed using TMS320C32 DSP adopted with CAN. The board communicates with other modules by CAN. so that mobile robots can perform several tasks in real time. So we can realize on autonomous mobile robot with basic functions such as obstacle avoidance by using the developed controller. Especially. this controller has 100 msec scan time for 16 sonar sensors and can detect closer objects comparing with standard sonar sensors.

• The Journal of the Acoustical Society of Korea
• /
• v.37 no.3
• /
• pp.139-146
• /
• 2018

Monostatic sonar systems localize targets using the time information of pulse transmission and receipt. Whereas, in asynchronous bistatic sonar systems, receivers need to detect direct blast to localize targets, since a source doesn't share pulse information with receivers. In this paper, we propose a direct blast detection algorithm, which estimates PRI (Pulse Repetition Interval) of direct blast and adaptive thresholds. Experimental results show the proposed algorithm has robust direct blast detection performance in the environment where strong background noise and target signal exist.

• Journal of Institute of Control, Robotics and Systems
• /
• v.11 no.4
• /
• pp.314-321
• /
• 2005

In this paper an intelligence embedding quadruped pet robot is described. It has 15 degrees of freedom and consists of various sensors such as CMOS image, voice recognition and sound localization, inclinometer, thermistor, real-time clock, tactile touch, PIR and IR to allows owners to interact with pet robot according to human's intention as well as the original features of pet animals. The architecture is flexible and adopts various embedded processors for handling sensors to provide modular structure. The pet robot is also used for additional purpose such like security, gaming visual tracking, and research platform. It is possible to generate various actions and behaviors and to download voice or music files to maintain a close relation of users. With cost-effective sensor, the pet robot is able to find its recharge station and recharge itself when its battery runs low. To facilitate programming of the robot, we support several development environments. Therefore, the developed system is a low-cost programmable entertainment robot platform.

• Nuclear Engineering and Technology
• /
• v.49 no.4
• /
• pp.781-786
• /
• 2017

The presence of crust on the inner walls of metallic ducts impairs transportation because crust completely or partially hinders the passage of fluid to the processing unit and causes damage to equipment connected to the production line. Its localization is crucial. With the development of the electronic imaging system installed at the Argonauta/Nuclear Engineering Institute (IEN)/National Nuclear Energy Commission (CNEN) reactor, it became possible to visualize crust in the interior of metallic piping of small diameter using real-time neutron radiography images obtained with a low neutron flux. The obtained images showed the resistance offered by crust on the passage of water inside the pipe. No discrepancy of the flow profile at the bottom of the pipe, before the crust region, was registered. However, after the passage of liquid through the pipe, images of the disturbances of the flow were clear and discrepancies in the flow profile were steep. This shows that this technique added the assembled apparatus was efficient for the visualization of the crust and of the two-phase flows.

• Journal of the Korean Professional Engineers Association
• /
• v.44 no.6
• /
• pp.40-44
• /
• 2011

Nuclear energy in Korea began in 1958, when the Korea's atomic energy act was formulated and the relevant organizations were founded. Since then, notwithstanding the two catastrophe like TMI and Chernobyl accident, Korea made a wise decision to expand the peaceful uses of the nuclear energy as well as to localize the essential nuclear design technology of fuel and nuclear steam supply system. This decision resulted in the success of export of nuclear power plants as well as research reactor in 2010s. The Korea's nuclear policy, which well utilized 'international crisis in nuclear business' as 'opportunity of Korea to get. nuclear technology', is believed nice policy as a role model of nuclear new-comer countries. Based upon the success story of localization of nuclear technology, Korea had an eye for a niche market, which was a basis of development of SMART, Korea-made integral PWR. The operation of a SMART plant can sufficiently provide not only electricity but also fresh water for 100,000 residents. Last two years, Korea's nuclear industry team led by the Korea Atomic Energy Research Institute completed the standard design of SMART and applied to the Korea's regulatory body for standard design approval. Now the Korea's licensing authority is reviewing the design with the relevant documents, and the design team is doing its best to realize its hope to get the approval by the end of this year. From next year, the SMART business including construction and export will be explored by the KEPCO consortium.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.60 no.11
• /
• pp.2176-2181
• /
• 2011

This paper estimates the life cycle cost(LCC) of a propulsion control system using the maintenance information in the high speed train(KTX-1). Life cycle costing is one of the most effective approaches for the cost analysis of long-life systems such as the KTX-1. Until now, most life cycle cost of the system has been studied as a whole system viewpoint. But in case of railway industry, LCC studies are needed on the subsystem like a propulsion control system because subsystems are developed continuously localization. This paper proposes the life cycle cost model which fitted to estimate life cycle cost (LCC) using maintenance information manual. As a result, LCC on propulsion control system increased moderately expect for periodical time when major parts are replaced at the same time. Results will be reflected in the development of domestic products.