• Title/Summary/Keyword: Living Factor

Search Result 1,793, Processing Time 0.023 seconds

The Inhibitory Effects of Yukmijihwang-tang-Hap-Sabaek-san and Root Cortex of Morus alba L. on the IL-6, IL-8 and GM-CSF mRNA Levels in Human Epithelial Cells (육미지황탕합사백산(六味地黃湯合瀉白散)과 상백피(桑白皮)가 인간 기관지상피세포의 IL-6, IL-8, GM-CSF mRNA level에 미치는 영향)

  • Hwang, Woo-Suck;Heo, Tae-Seok;Jung, Hee-Jae;Jung, Sung-Ki;Rhee, Hyung-Koo;Ju, Chang-Yeop
    • The Journal of Internal Korean Medicine
    • /
    • v.22 no.3
    • /
    • pp.415-422
    • /
    • 2001
  • Objectives: We aimed to identify the dose-dependent inhibitory effects of Yukmijihwang-tang-Hap-Sabaek-san(YMHSB) and Root cortex of Morus alba L.(RCM) on the mRNA expression of Interieukin(IL)-6, IL-S, granulocyte macrophage colony stimulating factor(GM-CSF) involved in the asthma model. Methods: In this study BEAS-2B cell lines, human epithelial cells, were used. These cells were stimulated by tumor necrosis $factor(TNF)-{\alpha},\;IL-1{\beta}$ and histamine for artificial inflammatory expression. ${\beta}-actin$ messenger RNA(mRNA) was used for the internal standard. After each 24 hours of the YMHSB and RCM treatment, total cellular RNAs were collected by treating RNA zol directly on the living cells. Then the transcriptional activities of IL-6, 8 and GM-CSF were measured by RT-PCR with electrophoresis. Results: In the YMHSB study, the mRNA expression of GM-CSF and IL-8 is significantly inhibited compared to that of control group. But the mRNA expression of IL-6 is not significantly inhibited. In the RCM study, the mRNA expression of GM-CSF and IL-S is significantly inhibited compared to that of control group. But the mRNA expression of IL-6 is not significantly inhibited. Conclusions: This study shows that YMHSB and RCM have dose-dependent inhibitory effects on the mRNA expression of IL-S and GMCSF in human epithelial cells. So these herbal medicines may inhibit the inflammatory process of asthma. Advanced studies are required to investigate the mechanisms of inhibition by herbal medicine in the asthma model.

  • PDF

The Development of Physical Functioning Scale for Community-Dwelling Older Persons (지역사회 노인의 신체기능 평가도구 개발)

  • Lee, Kyung-Jong;Han, Geun-Shik;Yoon, Soo-Jin;Lee, Yeon-Kyung;Kim, Chan-Ho;Kim, Jeong-Lim;Lee, Yun-Hwan
    • Journal of Preventive Medicine and Public Health
    • /
    • v.35 no.4
    • /
    • pp.359-374
    • /
    • 2002
  • Objectives : To develop a physical functioning instrument for older adults living in the community. Methods : A representative sample of 979 people aged 65 years or over were interviewed in-person. Of these, 199 people also completed a detailed in-hospital examination. The scale items were selected based on the frequency of endorsement, along with the item-total and inter-item correlations. The associations of the scale with their physical performance and clinical examination were analyzed to evaluate the criterion-related validity. Construct validity was assessed using factor analysis, and internal consistency through Cronbach's alpha and item-total correlations. Test-retest reliability was measured by agreement between the household survey and the repeat survey at the in-hospital examination. Results : Initially, 23 items on the level of difficulty, ranging from no difficulty to an inability to complete a task, with the specific mobility and self-care tasks were included. Those with a high frequency of endorsement and a low inter-item or item-total correlations were excluded, resulting in a 10-item Physical Functioning (PT) scale. Equal weights were given to each item and a summated score was calculated. Significant associations were found between the PF scores and the physical performance, surrey and clinical data. The scale revealed a 2-factor (mobility and self-care) structure. Cronbach's alpha was 0.92 and the item-total correlations were in the 0.63 to 0.78 range. Pearson's correlations for the test-retest ranged between 0.56 and 0.61. Conclusions : The newly developed Physical Functioning (PF) scale showed good psychometric properties in older people. Further work, however, is needed to improve its sensitivity to discriminate higher levels of functioning, in addition to assessing its predictive value in detecting changes in health.

A Study on Domestic Consumers' Needs and Importance-Performance Analysis of Selective Attributes for Developing Home Meal Replacement (HMR) Products (가정간편식 제품 개발을 위한 소비자의 요구도 및 선택속성의 중요도-만족도 분석)

  • Park, Sung-Bae;Lee, Hyun-Jun;Kim, Hae Young;Hwang, Hye-Sun;Park, Dae-Sub;Hong, Wan-Soo
    • Korean journal of food and cookery science
    • /
    • v.32 no.3
    • /
    • pp.342-352
    • /
    • 2016
  • Purpose: This study conducted an Importance-Performance Analysis (IPA) of selective attributes of Home Meal Replacement (HMR) as well as it examined the consumers' needs and willingness to buy HMR products to explore the need for developing more HMR products. Methods: This study was conducted among domestic consumers living in Seoul and its metropolitan areas, in the age range from the 20s to the 50s, and who had experience in purchasing HMR products. From the 490 surveys retrieved, 472 (96.3%) valid surveys were analyzed. Results: The analysis of the frequency of consuming HMR products showed the following results: 247 respondents answered '1-3 times a month' (52.3%); 167 respondents stated '1-2 times a week' (35.3%). With respect to the reason of purchase, 'simplicity of the recipe' was the most common, accounting for 188 respondents (39.8%), followed by 'time efficiency' accounting for 172 respondents (36.4%). Analysis of the demand for bibimbap (mixed rice) HMR products showed that 'chicken bibimbap' had the highest preference with 5.32 points, followed by 'bulgogi bibimbap' (5.08 points), and 'kimchi bibimbap' (4.96 points). In the case of HMR products that need to undergo further development, 'low-sodium products' received the highest points of 5.41 points, followed by 'small packaged products' (5.05 points), and 'functional products' (4.98 points). The factor analysis of the 13 selective attributes showed that they can be divided into 3 factors. The IPA analysis of the selective attributes of HMRs showed 'hygiene', 'taste', 'easy to go packaging', 'convenience in intake', and 'accessibility' in the 1st quadrant. In the 2nd quadrant, 'price' and 'freshness' were shown as the factors. In the 3rd quadrant, 'easy to serve', 'familiar food menu', and 'consistent menu' were shown as the leading factors, and in the 4th quadrant, 'saving labor' was the only factor. Conclusion: Based on these results, the research concludes that with respect to developing HMR products, there is a high demand for low sodium, low calorie, small packaged products; thus, showing the need to develop various HMR products for customer satisfaction. Furthermore, it shows that there is a need to consider developing HMR products that can maintain freshness at an affordable price.

Influence of Farming Practices on Weight-Length Relationship of the Loach (Misgurnus anguillicaudatus) Population in Rice Paddy Fields (영농방법이 논에 서식하는 미꾸리 개체군의 체중-체장 관계에 미치는 영향)

  • Kim, Myung-Hyun;Choi, Soon-Kun;Eo, Jinu;Kwon, Soon-Ik;Song, Young-Ju
    • Korean Journal of Environmental Biology
    • /
    • v.35 no.4
    • /
    • pp.446-451
    • /
    • 2017
  • The length frequency and weight-length relationships within the loach population of Misgurnus anguillicaudatus were investigated in environment-friendly (EFP) and conventional paddy fields (CP) in South Korea, in order to identify the influences of farming practices to the loach population living in paddy ecosystem. The size-frequency of distribution of M. anguillicaudatus populations noted to differ significantly when the loach populations of the EFP and the CP were compared. The mean weight and length of the loach population in EFP was greater than those of the loaches in CP. The equations based on weight and total length relationship in EFP and CP were $W=0.000004L^{3.0747}$ and $W=0.000002L^{3.2106}$, respectively. The condition factor (K) against total length of loaches at two paddy field types with different farming practices indicates that the loach population in EFP(mean K=0.95) had access to better nutritional conditions than those in CP (mean K=0.67). It therefore appears that the size and structure of loach populations in rice paddy fields might be affected by farming practices.

The Effect of Corporate Social Responsibility Activities on Brand Equity and Consumer Attitude (사회적 책임활동이 브랜드자산과 소비자태도에 미치는 영향 연구)

  • Park, Nam-Goo;Choi, Ho-Gyu
    • Journal of Distribution Science
    • /
    • v.12 no.8
    • /
    • pp.17-29
    • /
    • 2014
  • Purpose - The use of corporate social activities to implement the concept of corporate social responsibility enhances brand equity and attitude, and strengthens economic competitiveness. In areas such as mobile communications, companies take the responsibility of protecting customers and enhance the quality of the mobile communication service, helping to make an effort to obey the regulations of the public trade order and fair trade agreement, enabling a healthy society through communication with elderly living alone or youths without parents, and enhancing marketing strategies. Research design, data, and methodology - To test the hypothesis, a survey was conducted. The surveyed population includes people who use the big three mobile communication services. The survey was conducted from October 4th to October 14th, 2013. A total of 500 survey questionnaires were circulated and 483 were collected; out of these, 32 were excluded due to missing or incomprehensible information. The data was analyzed with SPSS 18.0 via frequency analysis, trust analysis, search factor analysis, relationship analysis, confirmation factor analysis using AMOS 18.0, and structural equation model analysis. Results - Research on corporate social responsibility has been frequently conducted recently. Companies are perceived as social constituents satisfying the social desires of people in addition to customer needs. Further, companies are returning profits to society to satisfy community needs, because there is greater emphasis on the social responsibilities of companies. Companies' social responsibilities should include marketing strategies and the identification of customer needs. This study shows that social service activities influence brand value, which influences customer attitudes; therefore, social service activities indirectly influence customer attitudes. In order to increase customers' purchasing intention, it is essential to improve brand image via social services and provide a distinctive quality of service. Conclusions - This research has used the purposive selection method in the empirical analysis to identify the effect of social services on brand value and customer attitude. Therefore, this study revealed that businesses, whose ultimate objective is to improve customers' purchasing intention, should promote their brand equity through corporate social responsibility activities and offer a distinct service quality. Limitations in the progress of research were found and future indications to overcome these limitations are suggested as follows. First, survey responders had a limited understanding of social responsibilities; therefore, this concept needs to be explained to people first. Second, the research was done on people who live in Daejeon; thus, it is not representative of the entire country. The research has to be repeated with people in other cities. Third, there is a limitation in the study because the purposive selection method was used on Daejeon customers. In the future, a more precise selection of the population is needed. Fourth, Daejeon has unique geographical and size characteristics. Thus, customers in Seoul and other areas may display different characteristics and research on them may reveal different findings. Therefore, again, this study has to be repeated in other areas.

Germination and Growth of Laminaria japonica (Phaeophyta) Microscopic Stages under Different Temperatures and Photon Irradiances (수온과 광량에 따른 다시마 초기 생활사의 발아와 성장)

  • KANG Rae-Seon;KOH Chul-Hwan
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.32 no.4
    • /
    • pp.438-443
    • /
    • 1999
  • Germination and growth of Laminaria japonica microscopic stages were investigated under crossed gradients of temperatures and irradiances, and the results related to the seasonal temperature regime in the southeastern coast of Korea. Germination rates of $70\~86\%$ were observed in the temperature range of $5\~20^{\circ}C$, however, at $25^{\circ}C$ no germination of meiospores was observed. The primary factor affecting germination rates at the temperature range of $5\~20^{\circ}C$ was irradiance: germination was significantly reduced at $150 {\mu}E{\cdot}m^{-2}{\cdot}s^{-1}$. Vegetative cell production of female gametophytes was highest at $20^{\circ}C$, but plants were not fertile at the temperature. In the temperature range of $5\~15^{\circ}C$, higher irradiance caused females to reduce cell production, but increased fertility. Cell production was also low at lower temperatures with increased fertility rates. Optimal growth temperature for microsporophytes was $10^{\circ}C$ and their growth rates were light-saturated at $70 {\mu}E{\cdot}m^{-2}{\cdot}s^{-1}$. We have concluded that meiospores released before July could develope to the young sporophytic stage in the southeastern coast of Korea which is off the southern limit of its geographical distribution. However, limiting factor in the development of natural sporophytic population in this region would be the upper temperature limit for the survival of young sporophytes, as water temperature at this area frequently exceeds $25^{\circ}C$ during the summer period.

  • PDF

Changes in density and culture conditions of the Manila Clam Ruditapes philippinarum on the West coast of Korea (서해안 바지락 양식장의 서식환경과 서식밀도의 변화)

  • Park, Kwang-Jae;Song, Jae-Hee;Choi, Yoon-Seok;An, Kyoung-Ho
    • The Korean Journal of Malacology
    • /
    • v.29 no.3
    • /
    • pp.207-216
    • /
    • 2013
  • Changes in density of manila clam, Ruditapes philippinarum to environment, catch and recruitment were studied in a few stations (Seonjae, Seongam, Hwangdo and Padori) in the West coast area of Korea from January, 2007 to December, 2009. Water temperature, salinity, dissolved oxygen and pH in the study stations were 0.8 to $31.2^{\circ}C$, 22.1 to 33.7 psu, 5.0 to 12.0 mg/L and 7.39 to 8.99, respectively. The concentrations of dissolved inorganic nitrogen, phosphate and silicate were 0.016 to 1.281 mg/L, 0.004 to 0.093 mg/L and 0.016 to 1.617 mg/L, respectively. Chlorophyll-a ranged from 0.2 to 12.1 ${\mu}g/L$, respectively. Substrata were mainly composed of muddy sand and very poorly sorted in Padori, muddy sand and well sorted in Seonjae and Hwangdo, gravelly muddy sand and poorly sorted in Seongam. Density was high in Seonjae and Seongam, but low in Hwangdo and Padori. In clam culture station, in which spat was naturally produced without sowing seedlings, the living density was decreased by increasing of death and a catch of shellfish, and recruitment was changed. Also, Density affected condition factor and shape of clam. Condition factor was the highest in Hwangdo, in which temperature in the winter and chlorophyll-a were high, and was the lowest in Padori. In the shape of clam, the shape in Seongam was a elongated form, but in Padori was a stunted form.

The effect of Self-sufficiency Project on Participants' Self-reliance and Satisfaction -Focusing on Self-sufficiency Participants in Ulsan Metropolitan City- (자활사업이 참여자의 자립의지 및 만족도에 미치는 영향 -울산광역시 자활참여자 중심으로-)

  • Park, Ju Young
    • The Journal of the Korea Contents Association
    • /
    • v.21 no.9
    • /
    • pp.580-594
    • /
    • 2021
  • The purpose of this paper is to investigate the impact on self-reliance and satisfaction of participants participating in the self-sufficiency business program of the Ulsan Metropolitan Regional Self-Sufficiency Center. A self-filled questionnaire was surveyed on self-sufficiency participants in five Borough and Country in Ulsan for 4 weeks from September 1 to 30, 2020, and final 233 copies were used in the actual analysis. As a result of the study, first, the percentage of positive responses of the participants was found to be good at 71.7%, for questions on the degree of support to the government, local governments, and administrative welfare centers. Second, in response to a system or service that would like to be supported or needed in the future, support for living expenses and support for health and medical expenses appeared and as a result of gender difference analysis, it was confirmed that there was a significant difference between support for children's education expenses and support for housing funds. Among the factors of the participant's psychological self-reliance(self-control, confidence, and willingness to work), the factor of self-control was the most significant factor, followed by confidence and willingness to work. Overall satisfaction with work was the highest among 9 satisfaction items such as salary and working hours.

An Analysis of the Effect of Mental Health and Leisure Competence on Participation in Archery and Satisfaction with Life (궁도 참여 노인의 정신건강, 여가 유능감이 궁도 참여도와 생활만족도에 미치는 구조모형 분석)

  • Kim, Hong Nam
    • 한국노년학
    • /
    • v.32 no.4
    • /
    • pp.1013-1023
    • /
    • 2012
  • This study aims to identify the effect of the mental health and leisure competence of senior citizen through participation in archery activity on satisfaction in their life. To achieve the purpose, the study interviewed members of the Archery and Sports Association living in Gwangju, Jeonnam and Jeonbuk using a questionnaire and collected 328 valid responses. The questions as measuring instruments such as leisure competence, depression, self-esteem, and satisfaction level which were developed by previous studies were revised for this study. For a statistics, a frequency analysis, a descriptive analysis, a correlation analysis, and a structural model analysis were conducted. As a result, first, the higher self-esteem of the subjects, the more they participated in archery and were satisfied with their life. Second, the lower depression they had, the more they participated in archery and were satisfied with their life. Third, as leisure competence of the subjects was not a main factor of archery participation, the related assumption was rejected. The mental health of the senior citizen such as self-esteem and depression was a factor of participation in archery and their satisfaction with their life grew higher through participation in archery.

Development and Validation of Authenticity Scale (진정성 척도 개발과 타당화)

  • Kim, Youngjun;Kim, Young-il;Lee, Heungchul;Kim, Kyungil
    • Korean Journal of Cognitive Science
    • /
    • v.32 no.3
    • /
    • pp.141-167
    • /
    • 2021
  • Authenticity is the opposite of hypocrisy or deceitful living in philosophy. While various positive factors that humans experience in life based on authenticity have been studied abroad, most of the studies in Korea that tried to measure authenticity did not take into account the characteristics of Korean culture or were developed only for the purpose of use in a limited domain or specific purpose. In this study, based on the specificity of Korean culture, we developed a measure of authenticity that researchers can use universally. To this end, the items constituting the existing authenticity scale and the items reflecting the cultural value of Korean society, which value social relationships, are integrated. The results of exploratory factor analysis and confirmatory factor analysis indicated that authenticity consists of three factors: self-awareness, behavioral authenticity, and relationship authenticity. In addition, criterion validity was verified based on correlations with life satisfaction, mindfulness, self-esteem, HEXACO, social desirability, self-regulation focus, and emotional diversity. These results suggest that the authenticity scale of this study is a reliable and valid measure, and is expected to be an important tool for empirical individual differences research on authenticity in everyday life in Korean population.