• Analytical Science and Technology
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• v.7 no.4
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• pp.441-453
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• 1994

Two extraction methods, liquid-liquid extraction(LLE) and solid-phase extraction(SPE), coupled with GC/MS were compared as preconcentration procedures for priority pollutants in water. Among the semi-volatile priority pollutants, 11 acid and 44 base/neutral compounds were spiked in reagent water. With LLE, which is a modification of EPA Method 625, the overall mean recovery of the 54 compounds was 91% with a mean relative standard deviation(RSD) of 4.6%. With SPE, the overall mean recovery of the 52 compounds was 53% with a mean RSD of 8.9%. The detection limits of both methods were in the range of $1{\sim}5{\mu}g/l$.

• Analytical Science and Technology
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• v.33 no.2
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• pp.59-67
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• 2020

Nadolol is a β-blocker drug, which effectively manages hypertension and angina pectoris. Its chemical structure allows the formation of four possible stereoisomers. A coupled column high-performance liquid chromatographic (HPLC) system with UV and fluorescence detection was investigated for simultaneously determining four nadolol enantiomers in human plasma. The plasma samples were prepared using a convenient liquid-liquid extraction process and passed through HPLC. Nadolol was initially separated from the endogenous compounds or other impurities in human plasma on a Phenomenex silica column, and its enantiomers were resolved and determined on a Chirapak AD-H column. The developed HPLC method achieved an effective chiral separation and significantly eliminated endogenous compound interference. This optimal HPLC method was validated following FDA guidelines. The results showed good selectivity, linearity, accuracy (90.50 % - 105.27 %), and precision (RSDs < 9.52 %) for each enantiomer. This method was also successfully applied to determine nadolol enantiomers in the plasma samples of a healthy male volunteer (after orally administering 80 mg racemic nadolol), proving its suitability for nadolol stereoselective pharmacokinetic studies.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1995.04b
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• pp.314-319
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• 1995

The effect of liquid level on the natural frequencies and mode shapes of a partially liquid-filled circular cylindrical shell with various boundary conditions is investigated by means of a theoretical analysis based upon Fourier series expansion method and a finite element analysis using ANSYS computer program. Two dimensional mode shapes of the liquid-coupled shell structure are obtained by the ANSYS finite element analysis and show that the liquid level affect the nodal point movement. It is found that the variation of normalized naturalfrequencies (natural frequencies of liquid-filled shell/antural frequencies ofempty shell) to the liquid level is depend on the axial mode numbers and circumferential wave numbers. Additionally, it is found that the number of variational steps of normalized natural frequencies is identicial to that of axial nodal points of the mode shape.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.3
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• pp.297-302
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• 2016

In this study, we prepared liquid crystal emulsions composed of $C_{12-20}$ alkyl glucoside, $C_{14-22}$ alcohol, and behenyl alcohol and performed structure analysis using various analytical equipment. First, as an important characteristic of liquid crystal emulsions, maltese cross patterns and multi-layer structure were observed by a polarized microscope and cryo-SEM. Also, formation of liquid crystal phase was confirmed by DSC and multi-layer lamellar structure having an interlayer spacing approximately $305{\AA}$ was confirmed by small angle x-ray scattering (SAXS). The alkyl chain arrangement formed orthorhombic structure of a lamellar structure of the liquid crystal emulsion was confirmed by wide angle x-ray scattering (WAXS). These results suggest that information on the various physical properties obtained through the research of liquid crystal emulsion structure is expected to be widely used in cosmetics development in the future.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2009.04a
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• pp.119-124
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• 2009

This paper proposes a tuned liquid column sloshing damper(TLCSD) and presents experimental results to evaluate its control performance. The proposed damper acts as a tuned liquid column damper(TLCD) and a tuned liquid damper(TLD), respectively, in both principal axes of building structures. Shaking table test was performed to grasp its dynamic characteristics. Testing results showed that under inclined incident excitations, a TLCSD used in this study have dynamic characteristics coupled by both TLCD and TLD.

• Journal of the Korean Society of Safety
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• v.18 no.1
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• pp.101-107
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• 2003

Dynamic behavior of flexible rectangular liquid storage structures is analysed by the developed method. The rectangular liquid storage structures are assumed to be fixed to the ground and a moving coordinate system is used. The irrotational motion of invicid and incompressible ideal fluid is represented by two analytic solutions. One is the solution of the fluid motion in the rigid rectangular liquid storage structure due to ground motions and the other is the solution of the fluid motion by the motion of the wall in the flexible rectangular liquid storage structure. The motion of structure is modeled by finite elements. The fluid-structure interaction effect is reflected into the coupled equation of motion as added fluid mass matrix. The free surface sloshing motion and hydrodynamic pressure acting on the wall in the flexible rectangular liquid storage structure due to the horizontal ground motion are obtained by the developed method and verified.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2002.09a
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• pp.98-105
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• 2002

The effects of the base-isolation system and elastic soil foundation on the behavior of a liquid storage tank are studied. To evaluate the seismic response of liquid storage tank accurately, the coupled dynamic system considering base isolation and soil interaction problem is formulated in time domain. Results show that the base isolation system reduces effectively the radial displacements, base shears, overturning moments, axial resultant stresses and the hydrodynamic pressure by providing flexibility and energy dissipation capability. Base Isolation may, however, increase the relative liquid sloshing amplitude due to the effect of liquid-structure interaction and cause excessive large relative displacements between structure and foundation. In addition to base-isolator, the dynamic behavior of liquid storage tank is related to the flexibility of base foundation, so the analysis of soil-structure interaction s achieved.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2009.11a
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• pp.38-41
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• 2009

For the technology development of LOx/kerosene liquid rocket engine, turbopump-gas generator closed-loop coupled tests using 30tonf main engine components such as turbopump and gas generator except combustion chamber are performed. In the engine system operation environment, simulating combustion chamber by flow control units, the chill-down procedure, startup characteristics, nominal operability and smooth shutdown of turbopump+gas generator closed-loop coupled Test Plant are successfully confirmed. The serviceability of the turbopump and gas generator are evaluated. The feed-back control system for the turbopump rotational speed and gas generator mixture ratio are also verified. The results of closed-loop coupled test will be used as the technology development for the liquid rocket engine.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.14 no.5
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• pp.1033-1042
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• 1994

Dynamic behavior of flexible rectangular liquid containers is analyzed by a two-dimensional coupled boundary element-finite element method. The irrotational motion of inviscid and incompressible ideal fluid is modeled by boundary elements and the motion of structure by finite elements. A singularity free integral formulation is employed for the implementation of boundary element method. Coupling is performed by using compatibility and equilibrium conditions along the interface between the fluid and structure. The fluid-structure interaction effects are reflected into the coupled equation of motion as added fluid mass matrix and sloshing stiffness matrix. By solving the eigen-problem for the coupled equation of motion, natural frequencies and mode shapes of coupled system are obtained. The free surface sloshing motion and hydrodynamic pressure developed in a flexible rectangular container due to horizontal and vertical ground motions are computed in time domain.

• Structural Engineering and Mechanics
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• v.29 no.1
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• pp.91-111
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• 2008

This paper outlines the development of a computational model in order to analyze the dynamic behaviour of coupled fluid-structure systems such as a) liquid containers, b) a set of parallel or radial plates. In this work a hybrid fluid-solid element is developed, capable of simulating both membrane and bending effects of the plate. The structural mass and stiffness matrices are determined using exact integration of governing equations which are derived using a combination of classical plate theory and a finite element approach. The Bernoulli equation and velocity potential function are used to describe the liquid pressure applied on the solid-fluid element. An impermeability condition assures a permanent contact at the fluid-structure interface. Applications of this model are presented for both parallel and radial plates as well as fluid-filled rectangular reservoir. The effect of physical parameters on the dynamic behaviour of a coupled fluid-structure system is investigated. The results obtained using the presented approach for dynamic characteristics such as natural frequency are in agreement to those calculated using other theories and experiments.