• Title/Summary/Keyword: Linear process

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Association of the initial level of enteral nutrition with clinical outcomes in severe and multiple trauma patients (초기 경장영양 공급 수준과 다발성 외상 중환자의 임상 경과와의 상관성 연구)

  • Yang, Suyoung;Jung, Seungyoun;Lee, Ji-hyun;Kwon, Junsik;Kim, Yuri
    • Journal of Nutrition and Health
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    • v.55 no.1
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    • pp.85-100
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    • 2022
  • Purpose: This study is aimed to examine the association between initial enteral nutrition (EN) and the clinical prognosis among patients with severe and multiple traumatic injuries, and to investigate whether this association is modified by the patients' catabolic status. Methods: This was a retrospective study of 302 adult patients with severe and multiple traumatic injuries admitted between January 2017 and September 2020 at Ajou University hospital in Suwon, Korea. The initial nutritional support by EN and parenteral nutrition were monitored up to day 7 after admission. Patients were classified into "No", "Low", and "High" EN groups according to the level of initial EN. Multivariable-adjusted logistic regression and linear regression models were used to estimate the association of the initial EN levels at hospital admission with the risk of mortality, morbidities, and levels of nutrition-associated biochemical markers. Results: High EN support was associated with reduced mortality (odds ratio, 0.07; 95% confidence interval [CI], 0.02, 0.32) and lower levels of C-reactive protein (β, -0.22; 95% CI, -8.66, 1.48), but longer stay in the intensive care unit (β, 0.19; 95% CI, 1.82, 11.32). In analyses stratified by catabolic status, there were fewer incidences of hospital-acquired infections with increasing EN levels in the moderate or higher nitrogen balance group than in the mild nitrogen balance group. Conclusion: Our observation of the inverse association between levels of initial EN administration with mortality risk and inflammatory markers may indicate the possible benefits of active EN administration to the recovery process of severe and multiple trauma patients. Further studies are warranted on whether the catabolic status modifies the association between the initial EN and prognosis.

Modelling Gas Production Induced Seismicity Using 2D Hydro-Mechanical Coupled Particle Flow Code: Case Study of Seismicity in the Natural Gas Field in Groningen Netherlands (2차원 수리-역학적 연계 입자유동코드를 사용한 가스생산 유발지진 모델링: 네덜란드 그로닝엔 천연가스전에서의 지진 사례 연구)

  • Jeoung Seok Yoon;Anne Strader;Jian Zhou;Onno Dijkstra;Ramon Secanell;Ki-Bok Min
    • Tunnel and Underground Space
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    • v.33 no.1
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    • pp.57-69
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    • 2023
  • In this study, we simulated induced seismicity in the Groningen natural gas reservoir using 2D hydro-mechanical coupled discrete element modelling (DEM). The code used is PFC2D (Particle Flow Code 2D), a commercial software developed by Itasca, and in order to apply to this study we further developed 1)initialization of inhomogeneous reservoir pressure distribution, 2)a non-linear pressure-time history boundary condition, 3)local stress field monitoring logic. We generated a 2D reservoir model with a size of 40 × 50 km2 and a complex fault system, and simulated years of pressure depletion with a time range between 1960 and 2020. We simulated fault system failure induced by pressure depletion and reproduced the spatiotemporal distribution of induced seismicity and assessed its failure mechanism. Also, we estimated the ground subsidence distribution and confirmed its similarity to the field measurements in the Groningen region. Through this study, we confirm the feasibility of the presented 2D hydro-mechanical coupled DEM in simulating the deformation of a complex fault system by hydro-mechanical coupled processes.

Growth Characteristics and Comparative Proteome Analysis of Adzuki Bean Leaves at the Early Vegetative Stage under Waterlogging Stress (논 토양 조건에서 팥 유묘기의 생육특성과 단백질 발현 양상)

  • Hae-Ryong Jeong;Soo-Jeong Kwon;Sung-Hyun Yun;Min-Young Park;Hee-Ock Boo;Hag-Hyun Kim;Moon-Soon Lee;Sun-Hee Woo
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.67 no.4
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    • pp.211-221
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    • 2022
  • Recently, the demand for the cultivation of upland soil has been increasing, and the rate of conversion of paddy soil into upland soil is also increasing. Theincrease in uneven precipitation due to climate change has resulted in dramatic effects of waterlogging stress on upland crops. Therefore, the present study was conducted to investigate the changes in growth characteristics and the expression patterns of proteins at the two-leaf stage of adzuki beans. The domestic cultivar, Arari (Miryang No. 8), was used to test waterlogging stress. At the two-leaf stage of adzuki beans, plant height slightly decreased androot fresh weight showed significant changes after 3 days of waterlogging treatment. Chlorophyll content was also significantly different after 3 days of waterlogging treatment compared to its content in control plants. Using two-dimensional gel electrophoresis, more than 400 protein spots were identified. Twenty-one differentially expressed proteins from the two-leaf stage were analyzed using linear trap quadrupole-Fourier transform-ion cyclotron resonance mass spectrometry. Of these 21 proteins, 9 were up-regulated and 12 were down-regulated under waterlogging treatment. Protein information resource (https://pir.georgetown.edu/) categories were assigned to all 49 proteins according to their molecular function, cellular component localization, and biological processes. Most of the proteins were found to be involved in the biological process, carbohydrate metabolism and were localized in chloroplasts.

Analysis of the Distribution and Diversity of the Microbial Community in Kimchi Samples from Central and Southern Regions in Korea Using Next-generation Sequencing (차세대 염기서열 분석법을 이용한 우리나라 중부지방과 남부지방의 김치 미생물 군집의 분포 및 다양성 분석)

  • Yunjeong Noh;Gwangsu Ha;Jinwon Kim;Soo-Young Lee;Do-Youn Jeong;Hee-Jong Yang
    • Journal of Life Science
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    • v.33 no.1
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    • pp.25-33
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    • 2023
  • The fermentation process of kimchi, which is a traditional Korean food, influences the resulting compo- sition of microorganisms, such as the genera Leuconostoc, Weissella, and Lactobacillus. In addition, several factors, including the type of kimchi, fermentation conditions, materials, and ingredients, can influence the distribution of the kimchi microbial community. In this study, next-generation sequencing (NGS) of kimchi samples obtained from central (Gangwon-do and Gyeonggi-do) and southern (Jeolla-do and Gyeongsang-do) regions in Korea was performed, and the microbial communities in samples from the two regions were compared. Good's coverage prediction for all samples was higher than 99%, indicating that there was sufficient reliability for comparative analysis. However, in a α -diversity analysis, there was no significant difference in species richness and diversity between samples. The Firmicutes phylum was common in both regions. At the species level, Weissella kandleri dominated in central (46.5%) and southern (30.8%) regions. Linear discriminant analysis effect size (LEfSe) analysis was performed to identify biomarkers representing the microbial community in each region. The LEfSe results pointed to statistically significant differences between the two regions in community composition, with Leuconostocaceae (71.4%) dominating in the central region and Lactobacillaceae (61.0%) dominating in the southern region. Based on these results, it can be concluded that the microbial communities of kimchi are significantly influenced by regional properties and that it can provide more useful scientific data to study the relationship between regional characteristics of kimchi and their microbial distribution.

Fundamental studies on thermosolutal convection in mercurous bromide(Hg2Br2) physical vapor transport processes (브로민화 수은(I)(Hg2Br2) 물리적 증착공정에서 온도농도대류의 기초연구)

  • Geug Tae Kim;Moo Hyun Kwon
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.33 no.3
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    • pp.110-115
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    • 2023
  • During the Hg2Br2 physical vapor transport process, with increasing the partial pressure of component B, PB from 40 Torr to 200 Torr, a unicellular convective flow structures move from the crystal growth region to the center region in the vapor phase. The boundary layer flow is dominant for PB = 40 Torr, and the core region flow is dominant for PB = 200 Torr. The flow in the vapor phase shows a three-dimensional convective flow structure with a single cell (unicellular) for PB = 40 Torr and 200 Torr, exhibits an asymmetrical flow with respect to the x, y central axis under the horizontally oriented configuration with an aspect ratio (length-to-width) of 3 and linear conducting walls. The critical temperature difference between the source and crystal region is about 30 K. The total molar flux of Hg2Br2 increases with the temperature difference until the total molar flux reaches the critical value. At the critical total molar flux, the total molar flux abruptly decreases.

Diversity and Succession of the Bacterial Community during the Initial Fermentation Period in Modernized Soy Sauce (Ganjang) (개량식 간장의 발효 초기 단계에서의 미생물 다양성 및 천이에 관한 연구)

  • Ho Jin Jeong;Gwangsu Ha;Jungmi Lee;Yeji Song;Do-Youn Jeong;Hee-Jong Yang
    • Journal of Life Science
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    • v.33 no.6
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    • pp.481-489
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    • 2023
  • The taste and quality of soy sauce, a fermented liquid condiment, is greatly influenced by microbial metabolism during fermentation. To investigate the microbiological characteristics of ganjang during the initial fermentation process, we prepared meju (fermented soybean) blocks fermented with starter cultures and solar salts and analyzed the microbial community quantitively using 16S rRNA gene profiling from ganjang that had been fermented over a five-week period. The ganjang samples were collected and analyzed after soaking for week one (1W), three (3W), and five (5W) weeks. We found that Halomonadaceae was significantly higher in the 1W group (89.83%) than the 3W and 5W groups (14.46%, and 13.78%, respectively). At a species level, Chromohalobacter beijerinckii and Chromohalobacter canadensis were the dominant species in the 1W group but several taxa such as Bacillus subtilis, Pediococcus acidilactici, and Enterococcus faecalis were more abundant in the 3W and 5W groups. Pearson correlation analysis of the relative abundance of the bacteria showed a negative correlation between Chromohalobacter and two bacterial genera Bacillus and Enterococcus. Beta-diversity showed a statistical distinction between the 1W and the 3W and 5W groups, while no significance was evident between the 3W and 5W groups. Linear discriminant effect size analysis was used to identify biomarkers and significant differences in the relative abundance of several halophilic bacteria, Bacillus sp. and lactic acid bacteria at 1W, 3W, and 5W, recpectively, which indicates the important role of the bacterial community at these time points.

Assessment of the Contribution of Weather, Vegetation, Land Use Change for Agricultural Reservoir and Stream Watershed using the SLURP model (I) - Preparation of Input Data for the Model - (SLURP 모형을 이용한 기후, 식생, 토지이용변화가 농업용 저수지유역과 하천유역에 미치는 기여도 평가(I) - 모형의 입력자료 구축 -)

  • Park, Geun-Ae;Lee, Yong-Jun;Shin, Hyung-Jin;Kim, Seong-Joon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.2B
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    • pp.107-120
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    • 2010
  • The effect of potential future climate change on the inflow of agricultural reservoir and its impact to downstream streamflow by reservoir operation for paddy irrigation water was assessed using the SLURP (semi-distributed land use-based runoff process), a physically based hydrological model. The fundamental input data (elevation, meteorological data, land use, soil, vegetation) was collected to calibrate and validate of the SLURP model for a 366.5 $km^2$ watershed including two agricultural reservoirs (Geumgwang and Gosam) located in Anseongcheon watershed. Then, the CCCma CGCM2 data by SRES (special report on emissions scenarios) A2 and B2 scenarios of the IPCC (intergovernmental panel on climate change) was used to assess the future potential climate change. The future weather data for the year, m ms, m5ms and 2amms was downscaled by Change Factor method through bias-correction using 3m years (1977-2006) weather data of 3 meteorological stations of the watershed. In addition, the future land uses were predicted by modified CA (cellular automata)-Markov technique using the time series land use data fromFactosat images. Also the future vegetation cover information was predicted and considered by the linear regression between monthly NDVI (normalized difference vegetation index) from NOAA AVHRR images and monthly mean temperature using eight years (1998-2006) data.

Analysis of Future Land Use and Climate Change Impact on Stream Discharge (미래토지이용 및 기후변화에 따른 하천유역의 유출특성 분석)

  • Ahn, So Ra;Lee, Yong Jun;Park, Geun Ae;Kim, Seong Joon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.2B
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    • pp.215-224
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    • 2008
  • The effect of streamflow considering future land use change and vegetation index information by climate change scenario was assessed using SLURP (Semi-distributed Land-Use Runoff Process) model. The model was calibrated and verified using 4 years (1999-2002) daily observed streamflow data for the upstream watershed ($260.4km^2$) of Gyeongan water level gauging station. By applying CA-Markov technique, the future land uses (2030, 2060, 2090) were predicted after test the comparison of 2004 Landsat land use and 2004 CA-Markov land use by 1996 and 2000 land use data. The future land use showed a tendency that the forest and paddy decreased while urban, grassland and bareground increased. The future vegetation indices (2030, 2060, 2090) were estimated by the equation of linear regression between monthly NDVI of NOAA AVHRR images and monthly mean temperature of 5 years (1998-2002). Using CCCma CGCM2 simulation result based on SRES A2 and B2 scenario (2030s, 2060s, 2090s) of IPCC and data were downscaled by Stochastic Spatio-Temporal Random Cascade Model (SST-RCM) technique, the model showed that the future runoff ratio was predicted from 13% to 34% while the runoff ratio of 1999-2002 was 59%. On the other hand, the impact on runoff ratio by land use change showed about 0.1% to 1% increase.

Analysis of Factors Affecting Health Inequalities Among Korean Elderly (노인 집단에서 나타나는 건강 수준 차이의 요인 분석)

  • Kim, Dongbae;Yoo, Byungsun;Min, Jungsun
    • Korean Journal of Social Welfare Studies
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    • v.42 no.3
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    • pp.267-290
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    • 2011
  • This research attempts to analyze the effects of demographic factors, socioeconomic factors, health behaviors and social/familial supports on health inequalities among Korean elderly. For this end, this study adopts the multiple linear regression analysis to process data on population aged over 65 contained in 'The Third Korea Welfare Panel Study' published in 2008. The following are the results. First, the less educated they are, the smaller income they earn, the less they drink, the less satisfied with relationships with their family members, the more they turn out to feel depressed. Second, the less educated they are, the smaller income they earn, the less they drink, the less they are satisfied with relationship with family members, the more they benefit from social welfare services, the worse they turn out to rate their health. Based on these findings, three following suggestions could be forwarded. First, vulnerable aged groups including female elderly, low-income elderly, less-educated elderly need customized social supports. Second, new social policy for households is required to enhance elderly people's satisfaction with their family relationships with the rapid trend of a growing number of nuclear families and aging. Third, social welfare service programs need to be reevaluated to enhance their function for the aged.

Characteristics of Steep Shingi Gully with Channelized Debris Flows (계곡형 토석류가 발생한 급경사 신기 계곡의 특성)

  • Park, Sang Doeg;Kim, Yong Hyun;Ham, Gwang Hyun;Son, Sang Jin;Na, Raksmey;Kim, Nam Jin
    • Journal of The Geomorphological Association of Korea
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    • v.28 no.3
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    • pp.13-26
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    • 2021
  • In mountain gully, channelized debris flow is an important phenomenon in the process of topographical change. Social infrastructure as roads may be damaged by channelized debris flows, but there has been little information about their occurrence and movement to prepare for the risk of the debris flow. Most of the channelized debris flows occur during heavy rains in mountainous valleys that are difficult to access, so there are not many field data. In this study, the topographical characteristics of the catchment, the rainfall and runoff related to the debris flow, the sedimentary pattern and the cross-sectional change of the channel bed, and the underflow velocity of the gravel bed have been investigated and analyzed in the Singi gully where the channelized debris flows occurred. In the catchment, there was almost no sediment runoff because the vegetation combine with the debris landforms and covered the surface. Therefore, the obvious cause of the channelized debris flows is the collapse of the slope and bed of the gully. Even if the gravel, cobbles, and boulders of the channel bed were lost by debris flow, the thalweg change due to debris flow may not be significant because they are supplied from the gully side slope normally. After the gabion structures were installed, the debris flow increased the thalweg change, bed erosion and side slope of the gully. Various sedimentary structures in the gully were classified according to the factors supporting the sedimentation. The hypsometric curve of the gully reflects the debris landforms and vegetation characteristics of the watershed and the sediment runoff due to debris flow, etc. The relationship between the flow velocity and the hydraulic gradient was non-linear under the condition that the porous medium with gully bed gravels is saturated with water. These results may be used as basic data for channelized debris flow research.