• International Journal of Oral Biology
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• v.42 no.1
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• pp.17-23
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• 2017

Background: Periodontitis is generally a chronic disorder characterized by the breakdown of tooth-supporting tissues. P. gingivalis, a Gram-negative anaerobic rod, is one of the major pathogens associated with periodontitis. Frequently, P. gingivalis infection leads to cell death. However, the correlation between P. gingivalis-induced cell death and periodontal inflammation remains to be elucidated. Among cell deaths, the death of immune cells appears to play a significant role in inflammatory response. Thus, the aim of this study was to examine P. gingivalis-induced cell death, focusing on autophagy and apoptosis in THP-1 cells. Methods: Human acute monocytic leukemia cell line (THP-1) was used for all experiments. Autophagy induced by P. gingivalis in THP-1 cells was examined by Cyto ID staining. Intracellular autophagic vacuoles were observed by fluorescence microscopy using staining Acridine orange (AO); and 3-methyladenine (3-MA) was used to inhibit autophagy. Total cell death was measured by LDH assay. Cytokine production was measured by an ELISA method. Results: P. gingivalis induced autophagy in an MOI-dependent manner in THP-1 cells, but 3-MA treatment decreased autophagy and increased the apoptotic blebs. P. gingivalis infection did not increase apoptosis compared to the control cells, whereas inhibition of autophagy by 3-MA significantly increased apoptosis in P. gingivalis-infected THP-1 cells. Inhibition of autophagy by 3-MA also increased total cell deaths and inflammatory cytokine production, including $IL-1{\beta}$ and $TNF-{\alpha}$. Conclusion: P. gingivalis induced autophagy in THP-1 cells, but the inhibition of autophagy by 3-MA stimulated apoptosis, leading to increased cell deaths and pro-inflammatory cytokines production. Hence, the modulation of cell deaths may provide a mechanism to fight against invading microorganisms in host cells and could be a promising way to control inflammation.

• Journal of Digital Convergence
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• v.18 no.4
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• pp.397-402
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• 2020

The purpose of this study is to identify the current state of coding education for children and to propose a new 'play-oriented' educational content to keep up with the problems of education in line with the revision process of the 4th Industrial Revolution. As a research method, we investigated and analyzed the case of the Korean early childhood coding education program, and then suggested the direction of the future infant coding education and suggested a new play area for children. Case analysis shows that current coding education places many restrictions on children's activities. So we propose a coding education space as a 'playing space' where children can actively play. Because the space is used, emotional education is possible because it can stimulate senses such as vision, touch and smell. In addition, this study is expected to cultivate not only spatial comprehension, but also imagination, creativity and cooperation. In future research, we will study the characteristics and technical process of children in-depth to help develop early childhood education.

• The Journal of Society for e-Business Studies
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• v.15 no.1
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• pp.103-118
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• 2010

In the past, the existing Internet service was used to simply gather information and show, with the development of Web 2.0 where everyone is allowed to access and share information. Since the development of the concept and the technology of the Web 2.0, the users of Social Network Service (SNS) such as Facebook, MySpace, Youtube, Twitter, etc., have been increasing. In this study, we researched into the Social Capital formed by using SNS based on "Social Capital Theory." We constructed the survey to obtain the demographical information of the users, motive of using the SNS and the evaluation of the On-line Social Capital. The survey was aimed for the Korean and the Chinese. In addition, a multi-regression analysis was performed to explain the relationship between the function of Social Network Service and the Online Social Capital. The result of this study, presents a relationship between the Online Social Capital form and function of Social Network Service users. Therefore, the information obtained in this study can be applied when developing the service.

• The Research Journal of the Costume Culture
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• v.13 no.4 s.57
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• pp.589-603
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• 2005

This study was to develop the design of briefs for elderly women, aiming at understanding about the briefs that the elderly women currently wear and helping them draw happiness from wearing clothes. This study, based on the data analyzing the physique of old women that was investigated by the previous study, targeted the elderly women living in Jeonbuk area to conduct the research into their physique, brieff that they prefer. The results of this study were as follows. First, the majority of the elderly women wore size 100 as looking into the size of briefs that elderly women put on and their physique. For the most part, they had relatively thinner waist compared to the belly and buttock. Second, they were found to have preference for briefs with narrow rubber band, and medium sized design that fit their line of buttock, waist and crotch, for reasons of the activity and comfort. Third, they were found to be generally happy with the briefs that they are currently wearing. Fourth, the factors leading elderly women to buy briefs were analyzed to come from the 4 considerations of beautiful appearance/customer service, practicality, economical reason/size and the comfortable feeling when wearing them. Among such factors, the greatest demand among those factors was the comfortable feeling they can have when they wear briefs, followed by the economical reason/size, practicality, beautiful appearance/customer service.

• Journal of Fashion Business
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• v.22 no.1
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• pp.1-19
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• 2018

The purpose of this study is to analyze the fashion style of Kate Middleton, the Royal Family, and to examine the social and cultural influence of Middleton fashion. We selected 314 photographs collected from a Google site and Gettyimages.com April 2011-December 2016 as the final research subjects. We categorized the situation by domestic events, royal events, diplomatic activities, and social contribution activities, and analyzed fashion styles focusing on item composition, color, material, silhouette, detail, trimming, and length. As a result of the study, the one piece was the highest in the combination of items, and the color was the most in white. The color tones were mostly vivid, and the material texture was silky. The image was classic, and the dress code was high in semi-formal. In a situational style, the coat was the most common at the Royal Family events and blue or white of the light tones appeared in the formal style of the classic image. In domestic events, there were many silky textures of modern image, and vivid, strong tonal knee length H line dress was the most prevalent. During diplomatic activities, various colors such as red, green, gray appeared in addition to blue or white and in social contribution activities, many dresses of vivid and dark tones of red appeared in the dress code as semi-formal. In conclusion, the stylistic features of Kate Middleton and the Royal Family are largely in the form of royal and noble, low cost and chic, and body-conscious styling.

• Journal of the Korean Society for Railway
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• v.19 no.2
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• pp.243-250
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• 2016

As sustainable growth has been emphasized in the field of transportation, the railway system has been promoted as an environmentally-friendly transport mode. However, mode shifts from other transport modes to railway have been sluggish. In this context, to enhance the understanding of railway's competitive advantages and disadvantages, this research evaluates travelers'preferences for public transport modes for inter-regional trips: such understanding should make it possible to formulate effective policy for promoting railways. To this end, passenger recognition of competitive transport modes has been measured by applying multidimensional scaling analysis for six major inter-regional public transport services - KTX, ITX-Samaeul, Mugunghwa-ho, premium express bus, general express bus, and airline. As a result, we can conceptualize the recognition similarity in two-dimensional space, and understand how travelers perceive the six major transport modes.

• Journal of Korean Elementary Science Education
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• v.39 no.1
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• pp.133-144
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• 2020

The purpose of this study is to identify the effect of Teacher Participation-oriented Education Program (TPEP) for Elementary School Teachers to Improve Class Expertise in Science Classes with a focus on visual attention. The participants were two elementary school teachers in Seoul and taught science subjects. The lesson topic applied to this study were 'Structure and Function of Our Body' in the second semester of fifth grade and 'Volcano and Earthquake' in the second semester of fourth grade. The mobile eye tracker SMI's ETG 2w, which is a binocular tracking system was used in this study. In this study, the actual practice time, participant's visual attention, visual intake time average, and visual intake time average were analyzed by class phase. The results of the study are as follows. First, as a result of analyzing the actual class execution time, the actual class execution time was almost in line with the lesson plan after the TPEP application. Second, visual attention in the areas related to teaching and learning activities was high after applying TPEP. Factors affecting the progress of the class and cognitive burdens were identified quantitatively and objectively through visual attention. Third, as a result of analyzing the visual intake time average of participants, there was a statistically significant difference in all classes. Fourth, as a result of analyzing the visual intake time average of participants, the results were statistically significant in the introduction(video), activity 1, activity 2, and activity 3 stages in the lecture type class. The Teacher Participation-oriented Education Program (TPEP) for Elementary School Teachers to Improve Class Expertise in Science Classes can extend elementary science class expertise such as self-class analysis, eye tracking, linguistic, gesture, and class design beyond traditional class analysis and consulting.

• Journal of the Korea Institute of Building Construction
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• v.18 no.3
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• pp.277-283
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• 2018

This study is conducted to improve the manufacturing process of the modular construction method, which is a pre-fabricated construction method recognized for its advantage on the shortening of construction time. This study first identified the factors that result in shortening of pre-fabrication processes in the current module-processing factory. In addition, those identified factors were further considered for installing the M.E.P. system that is being outsourced on the main module in the production line. A manufacturing process of the construction modules, which considers installation of a M.E.P. system most suitable for shortening the time on the outsourcing of modular construction, is introduced throughout the research. Furthermore, this study suggests the factors in need of improvement during design phase of modular construction and improvement measures to consider the quality of unit modules by focusing on the module parts that are most exposed to defects.

• The Journal of the Korea institute of electronic communication sciences
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• v.8 no.7
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• pp.1025-1032
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• 2013

The purpose of this study was to examine how socio-demographic characteristics and delinquent behaviors affect the suicidal ideation among the Korean high school students. Using the 35,668 senior high school student cases of 2009 Korean Youth Health Risk Behavior On-line Survey data, it conducted a secondary data analysis. Frequency analysis, chi-square test and logistic regression analysis was done. Being female, living without parents, low economic status, poor academic record, technical school students, young students, poor academic record, internet addition, problem drinking, smoking cigarettes and experience of drug use significantly increased probability of their suicidal thoughts. Findings may be used for tackle the issues of suicidal thoughts among the Korean senior high school students.

• Journal of the Korean Society of Clothing and Textiles
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• v.40 no.6
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• pp.967-978
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• 2016

This study examines consumers' multi-channel choices in the search phase and purchasing phase stage according to price sensitivity and product characteristics in order to propose a multichannel strategy. For the research, one-way ANOVA, t-test, clustering analysis, and crosstabs are used for the descriptive analysis of 317 surveys on men and women conducted in 2014. The findings are as follows. First, consumers that both experience goods and search goods rely on surrounding advice as well as a search channel regardless of price sensitivity. Second, channel selection differs by price sensitivity when it comes to purchasing phase. Consumers with high price sensitivity tend to purchase from online channels; however, consumers with low price sensitivity tend to purchase from off line channels in cases of search goods. Meanwhile, cases of experience goods have no meaningful result. Third, consumers are divided into 3 groups by the tendency of channel selection. In case of experience goods, search channel choice is aligned with purchasing channel; however, search channel choice is not aligned with purchasing channel in search goods. This study provides clear information on fashion consumers' behavior on multi-channel choices compared to ones for search goods consumers on strategic strategies for fashion companies.