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In-vitro Anticancer and Antioxidant Activity of Gold Nanoparticles Conjugate with Tabernaemontana divaricata flower SMs Against MCF -7 Breast Cancer Cells

  • Preetam Raj, J.P;Purushothaman, M;Ameer, Khusro;Panicker, Shirly George
    • Korean Chemical Engineering Research
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    • v.54 no.1
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    • pp.75-80
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    • 2016
  • Biologically stabilized gold nanoparticles were synthesized from the flower aqueous extract of T. divaricata. The synthesized nanoparticles were characterized by UV-Vis spectrophotometer, Zeta sizer, FTIR and TEM analysis. T. divaricata reduced gold nanoparticles having particle size and potential of 106.532 nm and -10.2 mV, respectively, with a characteristic peak of 550 nm in UV-visible spectrophotometer. FTIR graph after comparison between the crude flower extract and gold nanoparticles showed three major shifts in the functional groups. The morphology and size of the gold nanoparticles were examined by HRTEM analysis, which showed that most of the nanoparticles were nearly spherical with size of 100 nm. The gold nanoparticles synthesized demonstrated potent anticancer activity against MCF-7 cell line. The findings conclude that the antioxidant molecule present in T. divaricata may be responsible for both reduction and capping of gold nanoparticles which possess potential applications in medicine and pharmaceutical fields.

Implementation of Visualization System for Multi-sensor Data Analysis (다중 센서 데이터의 분석을 위한 가시화 시스템의 구현)

  • Kwon Hyuk-Don;Koo Sang-Ok;Jung Seung-Dae;Kim Bok-Dong;Jung Soon-Ki
    • Proceedings of the Korea Information Processing Society Conference
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    • 2006.05a
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    • pp.415-418
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    • 2006
  • 다양한 데이터에 대해 정확한 분석이 요구되는 분야가 증가하면서, 데이터를 효율적으로 가시화하는 방법에 대한 요구도 증가하고 있다. 분석에 효율적인 가시화란 데이터의 특성을 잘 표현함으로써 분석가가 데이터를 직관적으로 이해할 수 있도록 도와주는 것을 말한다. 이를 통해 데이터를 분석하는 시간을 줄이고 정확한 결과를 얻는데 도움을 준다. 본 논문에서는 가스 배관을 검사하기 위한 Geometry 피그(PIG:Pipeline Inspection Gauge)와 MFL 피그로부터 얻어지는 데이터를 다양한 방법으로 가시화하고 분석에 효과적인 가시화와 시스템의 구현에 대해 다룬다. 각 피그의 다중 센서를 통해 얻어온 데이터를 Line graph, Pseudo Color Image, 3D Surface, Polar View, 3D Pipeline View와 같은 다양한 방법으로 가시화하고 view들 간의 동기화 및 사용자 지정 view 배치를 통해 빠르고 정확한 분석을 가능하게 하는 여러 가지 방법에 대해 설명한다.

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A Spatial Data Cubes with Concept Hierarchy on Spatial Data Warehouse (공간 데이터 웨어하우스에서 개념 계층을 지원하는 공간 데이터 큐브)

  • Ok Geun-Hyoung;Lee Dong-Wook;You Byeong-Seob;Bae Hae-Young
    • Proceedings of the Korea Information Processing Society Conference
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    • 2006.05a
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    • pp.35-38
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    • 2006
  • 데이터 웨어하우스에서는 OLAP(On-Line Analytical Processing) 연산을 제공하기 위해 다차원 데이터를 큐브의 형태로 관리한다. 특히, 공간 차원과 같이 데이터 큐브의 차원에 개념 계층이 존재하는 경우 사용자는 특정 계층에 대한 집계 결과를 요구한다. 기조의 데이터 큐브의 구조들은 차원의 개념 계층을 지원하지 못하거나 지원하더라도 시간이나 공간적 비용에 대해 비효율적이다. 본 논문에서는 공간 데이터 웨어하우스에서 공간 개념 계층을 이용하여 효율적인 계층별 영역 집계연산을 지원하는 공간 데이터 큐브를 제안한다. 이는 개념 계층을 DAG(Directed Acyclic Graph) 형태로 표현하여 구성된 여러 개의 차원들을 공간차원의 지역성을 기준으로 연결한 구조이다. 이러한 구조를 갖는 큐브를 이용하면, 데이터 검색 시 상위 계층부터 아래 방향으로 탐색하기 때문에 각 차원에 대한 효율적인 검색이 가능하다. 특히, 공간 개념 계층에 대한 DAG를 이용하면, 공간적 지역성에 따른 영역 검색을 지원할 수 있다. 성능평가에서 개념 계층이 적용된 질의에 대한 실험을 통해 제안 기법이 기존 기법들에 비해 저장 공간 효율성 및 질의 응답 성능이 우수함을 증명한다.

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A study on Restructuring the Street Network for the Improvement of Traffic Problems in Metropolitan Central Area (대도시 도심교통문제의 개선을 위한 가로망체계의 개편방안에 관한 연구)

  • 임강원;임강원
    • Journal of Korean Society of Transportation
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    • v.5 no.2
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    • pp.81-95
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    • 1987
  • In line with the continued growth of car ownership, the traffic problems in central area of metropoles such as Seoul would become increasingly degraded. comparing with most western cities, the problems in Seoul are characterized by the improportionately high rates of intersection delay, station congestion, traffic accidents caused by weaving conflicts and pedestrian congestion. It is caused by the lack of flexibility I street network, which is prerequisite for upholding the efficacy of traffic management and control, resulted from the simplicity of network graph in terms of connectivity, street density and distribution by width. This pattern has been resulted from the prolonged policy pursuing the street-widening of the nagging bottleneck in such a short period since the 1950s, comparing that most western cities had undergone over several centuries an age of horse-and-vehicle transportation. In order to improve the expected traffic problems in central area over the coming periods of motorization, it is imperative to restructure the street network in Central Seoul so that the efficacy of traffic management and control may be operative. Based upon the long-range planning the street network should be restructured by stages so that cenral traffic may be controled by one-way operation and most through-traffic be detoured around fringe area.

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Short term Sensor's Drift Compensation by using Three Drift Correction Techniques (세 가지 드리프트 보정 기법을 이용한 단기 센서 드리프트 보정)

  • Jeon, Jin-Young;Choi, Jang-Sik;Byun, Hyung-Gi
    • Journal of Sensor Science and Technology
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    • v.25 no.4
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    • pp.291-296
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    • 2016
  • The ideal chemical sensor must show the similar result under the same condition for accurate measurement of gases regardless of time. However, the actual responses of chemical sensors have been shown the lacks of repeatability and reproducibility because of the drift which has been caused by aging and pollution of the sensor and the environment change such as temperature and humidity. If the problems are not properly taken into considerations, the stability and reliability of the system using chemical sensors would be decreased. In this paper, we analyzed the sensor's drift and applied the three different compensation methods(DWT( Discrete Wavelets Transform), Baseline Manipulation, Internal Normalization) for reducing the effects of the drift in order to improve the stability and the reliability of short term of the chemical sensors. And in order to compare the results of the methods, the standard deviation was used as a criterion. The sensor drift was analyzed by a trend line graph. We applied the three methods to the successive data measured for three days and compared the results. As a result of comparison, the standard deviation of DWT showed lowest value. (Before compensation: 7.1219, DWT: 1.3644, Baseline Manipulation: 2.5209, Internal Normalization: 3.1425).

Reducing the Search Space for Pathfinding in Navigation Meshes by Using Visibility Tests

  • Kim, Hyun-Gil;Yu, Kyeon-Ah;Kim, Jun-Tae
    • Journal of Electrical Engineering and Technology
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    • v.6 no.6
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    • pp.867-873
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    • 2011
  • A navigation mesh (NavMesh) is a suitable tool for the representation of a three-dimensional game world. A NavMesh consists of convex polygons covering free space, so the path can be found reliably without detecting collision with obstacles. The main disadvantage of a NavMesh is the huge state space. When the $A^*$ algorithm is applied to polygonal meshes for detailed terrain representation, the pathfinding can be inefficient due to the many states to be searched. In this paper, we propose a method to reduce the number of states searched by using visibility tests to achieve fast searching even on a detailed terrain with a large number of polygons. Our algorithm finds the visible vertices of the obstacles from the critical states and uses the heuristic function of $A^*$, defined as the distance to the goal through such visible vertices. The results show that the number of searched states can be substantially reduced compared to the $A^*$ search with a straight-line distance heuristic.

Modified Structural Modeling Method and Its Application: Behavior Analysis of Passengers for East Japan Railway Company

  • Nagata, Kiyoshi;Umezawa, Masashi;Amagasa, Michio;Sai, Fuyume
    • Industrial Engineering and Management Systems
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    • v.7 no.3
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    • pp.245-256
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    • 2008
  • In order to cope with the ill-defined problem of human behavior being immanent uncertainty, several methodologies have been studied in game theoretic, social psychological and political science frameworks. As methods to arrange system elements systematically and draw out the consenting structural model concretively, ISM, FSM and DEMATEL based on graph theory etc. have been proposed. In this paper, we propose a modified structural modeling method to recognize the nature of problem. We introduce the statistical method to adjust the establishment levels in group decision situation. From this, it will become possible to obtain effectively and smoothly the structural model of group members in comparison with the traditional methods. Further we propose a procedure for achieving the consenting structural model of group members based on the structural modeling method. By applying the method to recognize the nature of ill-defined problems, it will be possible to solve the given problem effectively and rationally. In order to inspect the effectiveness of the method, we conduct a practical problem as an empirical study: "Behavior analysis of passengers for the Joban line of East Japan Railway Company after new railway service of Tsukuba Express opened".

A Study on the Risk Assessment Method of Indoor-Impulsive Noise (실내 충격소음 위험 평가 방법에 관한 연구)

  • Chung, Sung Hak;Song, Ki Hyeok
    • Journal of the Korean Society of Safety
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    • v.31 no.2
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    • pp.90-97
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    • 2016
  • The objective of this study is to evaluate the operator's safety for the risk assessment method of impulsive noise division. Literature reviews on the basis of the impulsive noise study, the measuring methods and procedures, based on the results of the analysis process presents a risk assessment methods. In this study, analysis of the MIL-STD-1474D, B-duration graph for the peak noise level to cross the line from the measurement results is limited by the risk retracted. It is possible to determine whether there is quick can be determined whether the risk. Measurement positions measured by the microphone is installed on the risk of applying results are so located within the tolerance impulsive noise in the measurement position can interpret subjective safety is ensured. In addition, Proportional Dose technology was the proposed by the Patterson with the risk assessment method was applied to the indoor-impulsive noise. As results of this study, results for the same value of applying the technique of Proportional Dose technology results calculated by MIL-STD-1474D methods allows 1 count once increased in comparison to the result obtained.

An Application of advanced Dijkstra algorithm and Fuzzy rule to search a restoration topology in Distribution Systems (배전계통 사고복구 구성탐색을 위한 개선된 다익스트라 알고리즘과 퍼지규칙의 적용)

  • Kim, Hoon;Jeon, Young-Jae;Kim, Jae-Chul;Choi, Do-Hyuk;Chung, Yong-Chul;Choo, Dong-Wook
    • Proceedings of the KIEE Conference
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    • 2000.07a
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    • pp.537-540
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    • 2000
  • The Distribution System consist of many tie-line switches and sectionalizing switches, operated a radial type. When an outage occurs in Distribution System, outage areas are isolated by system switches, has to restored as soon as possible. At this time, system operator have to get a information about network topology for service restoration of outage areas. Therefore, the searching result of restorative topology has to fast computation time and reliable result topology for to restore a electric service to outage areas, equal to optimal switching operation problem. So, the problem can be defined as combinatorial optimization problem. The service restoration problem is so important problem which have outage area minimization, outage loss minimization. Many researcher is applying to the service restoration problem with various techniques. In this paper, advanced Dijkstra algorithm is applied to searching a restoration topology, is so efficient to searching a shortest path in graph type network. Additionally, fuzzy rules and operator are applied to overcome a fuzziness of correlation with input data. The present technique has superior results which are fast computation time and searching results than previous researches, demonstrated by example distribution model system which has 3 feeders, 26 buses. For a application capability to real distribution system, additionally demonstrated by real distribution system of KEPCO(Korea Electric Power Corporation) which has 8 feeders and 140 buses.

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A Study on the Hair Line detection Using Feature Points Matching in Hair Beauty Fashion Design (헤어 뷰티 패션 디자인 선별을 위한 특징 점 정합을 이용한 헤어 라인 검출)

  • 송선희;나상동;배용근
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.7 no.5
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    • pp.934-940
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    • 2003
  • In this paper, hair beauty fashion design feature points detection system is proposed. A hair models and hair face is represented as a graph where the nodes are placed at facial feature points labeled by their Gabor features and the edges are describes their spatial relations. An innovative flexible feature matching is proposed to perform features correspondence between hair models and the input image. This matching hair model works like random diffusion process in the image space by employing the locally competitive and globally corporative mechanism. The system works nicely on the face images under complicated background. pose variations and distorted by accessories. We demonstrate the benefits of our approach by its implementation on the face identification system.