• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7339-7344
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• 2013

To analyze the effects of a new unknown peptide DEF on the growth of tumor cells, a fused polypeptide TAT-DV1-DEF was designed and synthesized. The lung adenocarcinoma cell line GLC-82 treated with TAT-DV1-DEF was analyzed with a cell counting kit 8, and the location of polypeptides in cells was observed under laser confocal microscopy. The efficiency of polypeptide transfection and changes in nuclear morphology were analyzed by flow cytometry and fluorescence microscopy, respectively. Finally, the mechanism of tumor cell growth inhibition was evaluated by Western blotting. We found that TAT-DV1-DEF could significantly inhibit the growth of the lung adenocarcinoma cell line GLC-82, but not the normal human embryonic kidney cell line HEK-293. Polypeptides were found to be mostly localized in the cytoplasm and some mitochondria. The efficiency of polypeptide transfection in the two cell types was approximately 99%. Apoptotic nuclei were observed under fluorescence microscopy upon treatment with polypeptides and DAPI staining. Western blot analyses indicated that the polypeptide inhibition of tumor cell growth was apoptosis dependent. In the present study, we demonstrated that fused polypeptides could induce apoptosis of the lung adenocarcinoma cell line GLC-82, indicating that the new unknown peptide DEF has antitumor effects.

• Proceedings of the Korean Geotechical Society Conference
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• 2004.03b
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• pp.509-516
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• 2004

The measurement of abnormal change of temperature(temperature anomaly) will help determine the safety of various engineering constructions, as the measurement in body often used to diagnose one's health. Temperature anomaly can be occurred in leakage or seepage of water flow in rocks, and in ground water table etc. Grouting materials injected in fractured rocks generate heat during hardening process. The degree of temperature change is associated directly with heat flow characteristics, that is, thermal conductivity, specific heat capacity. density of the surrounding rocks and can afford to assess the grouting efficiency. However, in practice, the use of traditional temperature measuring technique composed of only one single thermal sensor has been fundamentally limited to acquire thermal data sufficient to use for that, partly due to the time-consuming measuring work, partly due to the non-consecutive quality of data. Thus, in this paper, a new concept of temperature measuring technique, what we call, thermal line sensor technique is introduced. In this, the sensors with an accuracy of $0.02^{\circ}$ are inserted at regular intervals in one line cable and addressed by a control device, which enables to fundamentally enhance the capability of data acquisition in time and space. This new technology has been demonstrated on diverse field model experiments. The results were simply meant to be illustrative of a potential to be used for various kinds of temperature measurements encountered in grouting and leakage problems.

• Korean Journal of Optics and Photonics
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• v.28 no.6
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• pp.295-303
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• 2017

In this paper, we have studied a method of forming a line beam using a UV LED. The existing linear-type UV LED curing optical system is composed of several cylindrical lenses, but problems such as optical system alignment, enlargement of the module, efficiency, etc. may arise in the future. As an alternative to these problems, a bar-type TIR lens having a freeform surface only in the y-axis direction is designed, to verify that it shows advantages in maximum illuminance, uniformity of illuminance, and flux efficiency.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.23 no.12
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• pp.127-135
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• 2009

In this paper, the Interleaved AC/DC boost converter using two inductor with voltage-doubler characteristic when it operates with a duty cycle greater than 0.5 is proposed. Generally, the low-line(Input AC 110[V]) operation of the AC/DC boost converter is much less efficient than high-line (Input AC 220[V]) operation. The proposed Interleaved AC/DC boost converter operates as a voltage doubler at low-line. Its low-line range have higher power factor and improved efficiency compared with that of conventional converter. This research proposed the Interleaved AC/DC boost converter for voltage-doubler characteristic. The principle of operation, feature and design considerations is illustrated and the validity of verified through the experiment with a 300[W] based experimental circuit.

• Smart Structures and Systems
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• v.14 no.6
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• pp.1197-1220
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• 2014

Accurate actuator tracking is critical to achieve reliable real-time hybrid simulation results for earthquake engineering research. The frequency-domain evaluation approach provides an innovative way for more quantitative post-simulation evaluation of actuator tracking errors compared with existing time domain based techniques. Utilizing the Fast Fourier Transform the approach analyzes the actuator error in terms of amplitude and phrase errors. Existing application of the approach requires using the complete length of the experimental data. To improve the computational efficiency, two techniques including data decimation and frequency decimation are analyzed to reduce the amount of data involved in the frequency-domain evaluation. The presented study aims to enhance the computational efficiency of the approach in order to utilize it for future on-line actuator tracking evaluation. Both computational simulation and laboratory experimental results are analyzed and recommendations on the two decimation factors are provided based on the findings from this study.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.50 no.7
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• pp.318-324
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• 2001

Efficiency optimization of an indirect vector controlled induction motor drive is proposed. The loss models are used in the validation of the fuzzy logic based on-line efficiency optimization control. At steady state, the fuzzy controller adaptively changes the excitation current on the basis of measured input power, until the maximum efficiency point is reached. The pulsating torque, due to flux reduction, has been compensated by an ingenious feedforward scheme. During transient state, rated flux is established to get the best transient response. Through a comprehensive simulation study, the results confirmed the validity of the proposed method.

• The KSFM Journal of Fluid Machinery
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• v.10 no.2 s.41
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• pp.22-31
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• 2007

This paper describes the shape optimization of rotor blade in a transonic axial compressor rotor. Three surrogate models, Kriging, radial basis neural network and response surface methods, are introduced to find optimum blade shape and to compare the characteristics of object function at each optimal design condition. Blade sweep, lean and skew are considered as design variables and adiabatic efficiency is selected as an objective function. Throughout the shape optimization of the compressor rotor, the predicted adiabatic efficiency has almost same value for three surrogate models. Among the three design variables, a blade sweep is the most sensitive on the object function. It is noted that the blade swept to backward and skewed to the blade pressure side is more effective to increase the adiabatic efficiency in the axial compressor Flow characteristics of an optimum blade are also compared with the results of reference blade.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.10
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• pp.1359-1367
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• 2000

In-situ particle monitors(ISPMs) are widely used for monitoring contaminant particles in vacuum-based semiconductor manufacturing equipment. In the present research, the performance of a Particle Measuring Systems(PMS) Vaculaz-2 ISPM at low pressures has been studied. We generated the uniform sized methylene blue particle beams using three identical aerodynamic lenses in the center of the vacuum line, and measured the detection efficiency of the ISPM. The effects of particle size, particle concentration, mass flow rate, system pressure, and arrangement of aerodynamic lenses on the detection efficiency of the ISPM were examined. Results show that the detection efficiency of the ISPM greatly depends on the mass flow rate, and the particle Stokes number. We also found that the optimum Stokes number ranges from 0.4 to 1.9 for the experimental conditions.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.07b
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• pp.1054-1056
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• 2002

High temperature Kermal diffusion from $POCl_3$ source usually used for conventional process through put of a cell manufacturing line and potentially reduce cell efficiency through bulk like time degradation. To fabricate high efficiency solar cells with minimal thermal processing, spin-on-doping(SOD) technique can be employed to emitter diffusion of a silicon solar cell. A technique is presented to emitter doping of a mono-crystalline solar cell using spin-on doping (SOD). Moreover it is shown that the sheet resistance variation with RTA temperature and time fer mono-crystalline and multi-crystalline silicon samples. This novel SOD technique was successfully used to produces 11.3% efficiency l04mm by 104mm size mono-crystalline silicon solar cells.

• Journal of the Korean Institute of Telematics and Electronics
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• v.24 no.5
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• pp.868-873
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• 1987

Holographic diffraction gratings which are the core element of the optical instruments such as a spectrophotometer have been fabricated using the photoresist as a recording material. A 488nm line from an argon laser is used in making the gratings. Transmission type surface-relief phase grating and reflection type which is fabsricated by coating the aluminum on the transmission type with thickness 2000\ulcornerare fabricated, the spatical frequency of which are 1200 lines/mm. Diffraction efficiency, scattered light and wave-front aberratin are measured to test the performance of the developed gratings. A marimum diffraction efficiency is given when light is incident at the Bragg angle. Theoretical efficiency is about 80%, but measured efficiency of the transmission type and reflection type is 50% and 45%, respectively.