• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.2
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• pp.423-428
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• 2010

In the initial design phase of superscalar microprocessors, a performance model is necessary. A theoretic performance model is very useful since performance for various architecture parameters can be obtained by simply computing equations, without repeating simulations, Previous studies established theoretic performance models using the relation between the instruction window size and the issue width, with the penalties due to branch mispredictions and cache misses. However, the study was intended for unlimited number of functional units, which is insufficient for the real case application. This paper proposes a superscalar microprocessor theoretical performance model which also works for the limited functional units. To enhance the accuracy of our limited functional unit model, instruction dependency rates are employed. By using trace-driven data of SPEC 2000 integer programs as input, this paper shows that the theoretically computed performance of superscalar microprocessor with limited number of functional units is quite similar to the measured performance.

• Journal of the Korean Society of Clothing and Textiles
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• v.37 no.3
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• pp.247-259
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• 2013

This study conceptually approaches and clearly compares the similarities and differences of fashion and architecture through a focus on their correlations. This study identifies the conceptual definitions of functional minimalism by an examination of function that represents the largest similarity between architecture and fashion. This study classifies the nature of functional minimalism and studies cases for each architectural classification in the areas of: the simplicity of a structure, unitarity pursuit of economic value, repeatability in an efficiency unit, reducibility stressing property, and multi-functional spatiality. The characteristics of functional minimalism fashion are distinguish as: simplicity in a structure that highlight structural lines in non-decorated design, unitarity pursuit of economic value represented in united process and pattern for its economic effect, repeatability in an efficiency unit represented through the repeated decoration of a functional unit, reducibility stressing a property that emphasizes property with a dominant design element through a highlight of the characteristics of materials and multi-functional spatiality that represents variability in clothes through an expansion of limited spatial function. This study approaches each discipline with a clear understanding of the differences between the two and suggests standards for a comparative study of architecture and fashion.

• The Journal of Korean Physical Therapy
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• v.13 no.3
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• pp.643-651
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• 2001

Osteoarthritis(OA) is a widespread, slowly developing disease with a high prevalence rate increasing with age. The most common big joints involved in OA is the knee, where the disease particulary strikes, causing difficulties in rising from a chair. climbing stairs, kneeling. standing, and walking. The primary complaints of these patients include pain, stiffness. instability, and loss of function. The purpose of this study was to assess the impact of self-reported symptoms and limited flexion, and limited extension on functional impairment in patients with knee osteoarthritis. In the data collection, a total of 206 who had visited the physiotherapy unit at six different departments of orthopedics were interviewed in K City from June to September, 2000. The results of the study summarized are as fellows: 1. There was a significant difference among different degree group of limited flexion(p<0.05). A group difference was demonstrated between <5 ${\sim}$ 15 and 16 > (F=16.21, p<0.05). In the relationship between the degree of limited flexion and the level of functional impairment, the h igher the range of limited flexion, the lower the level of functional impairment. 2. In the relationship between the degree of limited extension and the level of functional impairment, a group difference was revealed between the non-limitation group and the <10 and 11 < However, no significant difference was noted between 11 ${\sim}$ 20 and 21 >(F= 13.37, p<0.05). In conclusion, finding above suggest that functional impairment is closely correlated with limited tlexion and extenion

• Journal of Microbiology and Biotechnology
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• v.26 no.5
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• pp.854-866
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• 2016

The production cost of biodiesel from microalgae is still not competitive, compared with that of petroleum fuels. The genetic improvement of microalgal strains to increase triacylglycerol (TAG) accumulation is one way to reduce production costs. One of the most promising approaches is the isolation of starch-deficient mutants, which have been reported to successfully increase TAG yields. To date, such a stable mutant is not available in an oleaginous marine microalga, despite several advantages of using marine species for biodiesel production. Algae in the genus Dunaliella are known to tolerate high salt concentration and other environmental stresses. In addition, the cultivation processes for large-scale outdoor commercialization have been well established for this genus. In this study, Dunaliella tertiolecta was used to screen for starch-deficient mutants, using an iodine vapor-staining method. Four out of 20,016 UV-mutagenized strains showed a substantial reduction of starch content. A significantly higher TAG content, up to 3-fold of the wild-type level, was observed in three of the mutants upon induction by nitrogen depletion. The carotenoid production and growth characteristics of these mutants, under both normal and oxidative stress conditions, were not compromised, suggesting that these processes are not necessarily affected by starch deficiency. The results from this work open up new possibilities for exploring Dunaliella for biodiesel production.

• Journal of The Korea Institute of Healthcare Architecture
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• v.16 no.1
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• pp.35-42
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• 2010

As a functionally complicated facility, it requires rational strategy to accommodate multi-functional needs to plan a hospital. Ambulatory surgery units located in large hospitals have problems such as longer waiting time and congestion for patients due to complicated planning and organization within limited area, which raise needs for independent ambulatory surgery centers to enable smoother medical treatment for patients. To design an independent ambulatory surgery center, understanding of zoning and layout of each unit needs is particularly required. This study focuses on research of efficient zoning/organization of day surgery unit and circulation arrangements of ambulatory surgery centers by analyzing various examples abroad, which will eventually help finding appropriate way of planning domestic ambulatory surgery centers. Specific area of research includes ambulatory surgery process, programmatic requirements, spatial organization of the facility, layout of surgery unit and circulation arrangements of ambulatory surgery centers.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10887-10891
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• 2015

Background: Helicobacter pylori (H. pylori) is a well known major cause of gastric cancer and even when asymptomatic infected patients are at elevated risk. Functional dyspepsia (FD) is also one of the most common gastrointestinal diseases, which greatly impacts the quality of life. H. pylori infection and psychosocial stress are frequently associated with FD but limited studies have confirmed the relationships, especially in Southeast Asian countries. Here we aimed to investigate the prevalence and impact of H. pylori infection, anxiety and depression on Thai FD patients. Materials and Methods: This cross-sectional study was conducted in a tertiary care center in Thailand, during February 2013-January 2014. All FD patients were diagnosed and categorized by Rome III criteria into epigastric pain syndrome (EPS) and postprandial distress syndrome (PDS) groups. The Hospital Anxiety and Depression Scale was used to evaluate psychological status. The presence of H. pylori was defined as positive with H. pylori culture, positive rapid urease test or positive histology. Results: Three hundred FD patients were included, 174 (58%) female. Overall mean age was 54.8+15.1 years. There were 192 (64%) patients with PDS and 108 (36%) with EPS. H. pylori infection was demonstrated in 70 (23.3%) patients. Anxiety and depression were documented in 69 (23%) and 22 (7.3%), respectively. H. pylori infection, anxiety and depression were significantly higher in PDS than EPS patients (27.1% vs 16.7%; p=0.04; OR=1.86; 95%CI=1.01-3.53 and 29.7% vs 11.1%; p=0.0002; OR=3.4; 95%CI=1.7-7.1 and 10.4% vs 1.9%; p=0.006; OR=6.2; 95%CI=1.4-38.9, respectively). Conclusions: H. pylori infection, anxiety and depression were commonly found in Thai FD patients and more prevalent in PDS than EPS. H. pylori eradication might be the key to success for the treatment of Thai FD patients and prevent the development of gastric cancer.

• Journal of Microbiology and Biotechnology
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• v.22 no.6
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• pp.780-787
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• 2012

The maize pathogen Gibberella moniliformis produces fumonisins, a group of mycotoxins associated with several disorders in animals and humans, including cancer. The current focus of our research is to understand the regulatory mechanisms involved in fumonisin biosynthesis. In this study, we employed a proteomics approach to identify novel genes involved in the fumonisin biosynthesis under nitrogen stress. The combination of genome sequence, mutant strains, EST database, microarrays, and proteomics offers an opportunity to advance our understanding of this process. We investigated the response of the G. moniliformis proteome in limited nitrogen (N0, fumonisin-inducing) and excess nitrogen (N+, fumonisin-repressing) conditions by one- and two-dimensional electrophoresis. We selected 11 differentially expressed proteins, six from limited nitrogen conditions and five from excess nitrogen conditions, and determined the sequences by peptide mass fingerprinting and MS/MS spectrophotometry. Subsequently, we identified the EST sequences corresponding to the proteins and studied their expression profiles in different culture conditions. Through the comparative analysis of gene and protein expression data, we identified three candidate genes for functional analysis and our results provided valuable clues regarding the regulatory mechanisms of fumonisin biosynthesis.

• Journal of Yeungnam Medical Science
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• v.21 no.2
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• pp.167-176
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• 2004

Background: Electromagnetic fields (EMF) are ubiquitous in modern society including medical field. As the technology of medical instruments and telecommunications has developed rapidly, it has influenced on our lives in many ways. Modern medical practice requires high quality medical equipments, which have a great deal of electromagnetic interference and susceptibility. The purpose of this study were to evaluate electromagnetic condition under usual clinical condition and to suggest a practical guideline in general hospital. Materials and Methods: The actual state of the electromagnetic interference in the medical field was studied under usual clinical conditions including operating rooms, intensive care units, magnetic resonance imaging unit, and hyperthermia unit. Results: There was considerable noise as a result of electromagnetic fields from medical equipments including electrosurgical units and hyperthermia unit, and cellular phones, which could induce serious functional derangements of functioning medical devices. Conclusion: It will be necessary to evaluate the individual electromagnetic situations under various medical conditions and to define a limited zone for cellular phone as well as reposition medical equipments to secure a safer medical practice and to minimize electromagnetic interference.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.35 no.4
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• pp.16-23
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• 2012

At present, the significance of a new manufacturing system that can shift from 'mass production' and consider life cycles of a product is pointed out and extremely expected. In such a situation, it is recognized that the modular design, often called 'unit design,' is the important design methodology which realizes the new production system enabling 'cost reduction,' 'flexible production of a multi-functional artifact,' 'settlement of an environmental issue,' and so on. A module (unit) of a product is generally defined as 'the parts group made into the sub-system from a certain specific viewpoint.' So far, there have been many researches related to the modular design. However, they are often limited to a certain viewpoint (objective). This paper proposes a simple but effective method for multi-objective modular design. In the proposed method, a new design metric, called similarity index, is proposed to evaluate the modular design candidates from the multiple viewpoints.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.38 no.12
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• pp.44-55
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• 2001

MAC(Multiply and ACcumulate) is the core operation of multimedia data processing. Because MAC units implemented on traditional DSP units or embedded processors have latency of three cycles and cannot operate on multiple data simultaneously, then, performances are seriously limited. Many high end general purpose microprocessors have SIMD MAC unit as a functional unit. But these high end MAC units must support pipeline structure for various operation modes and high clock frequency, which makes control logic complex and increases chip area. In this paper, a 64bit SIMD MAC unit for embedded processors is designed. It is implemented to have a latency of one clock cycle to remove pipeline control logics and a minimal area overhead for SIMD support is added to existing Booth multipliers.