• Title/Summary/Keyword: Limited Life

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Life Estimation of Hot Forging Die by Plastic Deformation and Wear (소성변형 밀 마멸에 대한 열간 단조 금형의 수명 평가)

  • 이현철;김병민;김광호
    • Journal of the Korean Society for Precision Engineering
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    • v.20 no.2
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    • pp.66-75
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    • 2003
  • This paper describes about the estimation method of die lift by wear and plastic deformation in hot forging process. The thermal load and the thermal softening are happened by the high temperature in hot forging process. Tool lift decreases considerably due to the softening of the surface layer of a tool caused by high thermal load and long contact time between tool and billet. Also, tool life is to a large extent limited by wear, heat crack and plastic deformation in hot forging process. Above all, the main factors which affects die accuracy and tool lift are wear and the plastic deformation of a die. The new developed technique for predicting tool life applied to estimate the production quantity for a spindle component and these techniques assist to improve the tool life in hot forging process.

Role of Water in Bread Staling: A Review

  • Choi, Young-Jin;Ahn, Soon-Cheol;Choi, Hyun-Shik;Hwang, Duck-Ki;Kim, Byung-Yong;Baik, Moo-Yeol
    • Food Science and Biotechnology
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    • v.17 no.6
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    • pp.1139-1145
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    • 2008
  • Bread is an essential food consumed worldwide. Bread rapidly loses its desirable texture and flavor qualities associated with freshness through a process known as staling. The shelf life of bread is limited by this staling leading to economical losses in the range of one billion dollars per year. There are a number of mechanisms thought to be related to the staling process, such as water migration and redistribution, starch retrogradation, and gluten transformation. In this review, roles of water and water migration on bread staling are summarized and discussed.

Overview of hepatitis B and C infection (B형 및 C형 간염의 이해)

  • Kim, Ji-Hoon
    • The Journal of the Korean life insurance medical association
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    • v.30 no.1
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    • pp.11-20
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    • 2011
  • Both the enterically transmitted forms of viral hepatitis, hepatitis A and E are self-limited and do not cause chroni chepatitis. Chronic hepatitis occurs in patients with hepatitis B and C as well as in patients with chronic hepatitis D superimposed on chronic hepatitis B. Chronic hepatitis such as hepatitis B or C is important in terms of insurance underwriting and claims. General review of hepatitis B and C was performed in this article.

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Phylogenetic relationship of the wild silkworm, Bombyx mandarina, inferred from aninternal transcribed spacer (ITS) of rDNA

  • Kim, Kyung-ah;Nho, Si-kab
    • Proceedings of the Korean Society of Sericultural Science Conference
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    • 2003.04a
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    • pp.42-42
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    • 2003
  • The wild silkworm, Bombyx mandarina, was believed the only ancestor of B. mori, inhabits the limited area of Eastern Asia including China, Korea and Japan. However, the geographic dimorphism of B. mandarina was reported with chromosome number and arylphorin gene. In connection with those dimorphism, we studied the genetic differences of ITS-2 region in rDNA purposing the differentiation and geographic variation within the species of B. mandarina. (omitted)

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A Longitudinal Analysis of the Association between Transition into Marriage and Life Satisfaction and Childhood Parental Divorce as a Moderator (결혼과 삶의 만족도의 관계에 대한 종단분석 및 아동기 부모 이혼의 조절효과)

  • Lee, Yoonjoo
    • Human Ecology Research
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    • v.59 no.1
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    • pp.113-125
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    • 2021
  • Previous research on the association between marriage and life satisfaction is limited due to the lack of attempts to investigate the time profiles of life satisfaction around marriage. This study addresses unresolved questions about the positive association between marriage and life satisfaction as well as tests if it is moderated by childhood parental divorce. Using 14 waves of the Korean Welfare Panel Study(N=3,890 individuals or 25,338 person-year observations), the author first used an ordinary least squares model with clustered standard errors and found that married people reported higher life satisfaction before marriage, compared to people who remained single during the survey. This result supports a social selection perspective. Next, the author used a fixed effects regression model and found that the transition into marriage was associated with an initial rise and subsequent decline in life satisfaction. Life satisfaction increased after reaching its lowest level in the third year of marriage. Life satisfaction after the transition into marriage was significantly higher than that observed three or more years prior to marriage. The result supports a social causation perspective. Such changing patterns were not moderated by parental divorce during childhood. This study advances the current literature on marriage and life satisfaction by using a nationally representative longitudinal data set as well as by testing social selection and causation perspectives.

Impacts of death perceptions, terminal care stress, and life satisfaction on attitudes toward end-of-life care among nurses at a tertiary hospital (죽음인식, 임종간호 스트레스, 삶의 만족도가 상급종합병원 간호사의 임종간호태도에 미치는 영향)

  • Yoon Young Shin;Haejung Lee
    • Journal of Korean Biological Nursing Science
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    • v.26 no.3
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    • pp.218-227
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    • 2024
  • Purpose: This study investigated the factors influencing attitudes toward end-of-life care among nurses at a tertiary hospital in Korea. Specifically, it examined the roles of nurses' characteristics, death perceptions, terminal care stress, and life satisfaction. Methods: The participants included 150 nurses working at a tertiary hospital, who were recruited between August 15 and September 19, 2023. Data were collected through an online survey and analyzed using descriptive statistics, the t-test, analysis of variance, Pearson correlation coefficients, and multiple regression analysis with SPSS/WIN 28.0. Results: Nurses' attitudes toward end-of-life care were positively correlated with death perceptions (β = .28, p < .001), 3 years or more of clinical experience (β = .25, p = .001), the experience of an acquaintance death (β = .22, p = .002) and life satisfaction (β = .20, p = .004). These variables explained 34.0% of the total variance in attitudes toward end-of-life care. Conclusion: It is essential to develop and implement individualized end-of-life nursing education programs, particularly utilizing simulations, for nurses with limited clinical experience and low levels of death perceptions. Further research should explore attitudes toward end-of-life care among various healthcare providers with a broader regional scope to improve the overall quality of end-of-life care.

An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts

  • Cho, Sung-Yup;Kang, Wonyoung;Han, Jee Yun;Min, Seoyeon;Kang, Jinjoo;Lee, Ahra;Kwon, Jee Young;Lee, Charles;Park, Hansoo
    • Molecules and Cells
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    • v.39 no.2
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    • pp.77-86
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    • 2016
  • Cancer is a heterogeneous disease caused by diverse genomic alterations in oncogenes and tumor suppressor genes. Despite recent advances in high-throughput sequencing technologies and development of targeted therapies, novel cancer drug development is limited due to the high attrition rate from clinical studies. Patient-derived xenografts (PDX), which are established by the transfer of patient tumors into immunodeficient mice, serve as a platform for co-clinical trials by enabling the integration of clinical data, genomic profiles, and drug responsiveness data to determine precisely targeted therapies. PDX models retain many of the key characteristics of patients' tumors including histology, genomic signature, cellular heterogeneity, and drug responsiveness. These models can also be applied to the development of biomarkers for drug responsiveness and personalized drug selection. This review summarizes our current knowledge of this field, including methodologic aspects, applications in drug development, challenges and limitations, and utilization for precision cancer medicine.

A Study on the Effectiveness of Floor Area Ratio Incentive System for Long-Life Housing Certification System (사례 분석을 통한 장수명주택의 용적률 인센티브 실효성 검토)

  • Jung, Yoon-Hye;Kang, Ji-Yeon;Kim, Hyung-Geun;Park, Ji-Young
    • Land and Housing Review
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    • v.11 no.2
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    • pp.69-74
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    • 2020
  • The purpose of this study is to investigate the effect of floor area ratio incentive system for Long-life housing certification system by simulation of five recently built apartment complexes. Apartments that are certified as superior in Long-life housing can receive 10% of the floor are incentive in Seoul. However, the difference between base and permitted floor area ratio are in general residential area of class 2 and 3 is not more than 20%. limit of feasible allowance incentive is limited. Even if there is an unrealized permitted floor area ratio, there is no reason to apply the Long-life housing certification system preferentially. Because the items of the floor area ratio incentive provided by the District Unit Plan are various, it shows that the floor space ratio incentive for Long-life housing certification system has little effectiveness. To enhance the feasibility of incentives for the Long-life housing certification system, improvement in the urban planning level, including district unit planning, including the design criteria for apartments in Seoul, is needed.

Comparison of Bacterial Community of Healthy and Erwinia amylovora Infected Apples

  • Kim, Su-Hyeon;Cho, Gyoengjun;Lee, Su In;Kim, Da-Ran;Kwak, Youn-Sig
    • The Plant Pathology Journal
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    • v.37 no.4
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    • pp.396-403
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    • 2021
  • Fire blight disease, caused by Erwinia amylovora, could damage rosaceous plants such as apples, pears, and raspberries. In this study, we designed to understand how E. amylovora affected other bacterial communities on apple rhizosphere; twig and fruit endosphere; and leaf, and fruit episphere. Limited studies on the understanding of the microbial community of apples and changes the community structure by occurrence of the fire blight disease were conducted. As result of these experiments, the infected trees had low species richness and operational taxonomic unit diversity when compared to healthy trees. Rhizospheric bacterial communities were stable regardless of infection. But the communities in endosphere and episphere were significanlty affected by E. amylovora infection. We also found that several metabolic pathways differ significantly between infected and healthy trees. In particular, we observed differences in sugar metabolites. The finding provides that sucrose metabolites are important for colonization of E. amylovora in host tissue. Our results provide fundamental information on the microbial community structures between E. amylovora infected and uninfected trees, which will contribute to developing novel control strategies for the fire blight disease.