• Title/Summary/Keyword: Lignans

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Antioxidative Activities of Triterpenoids and Lignans from Acanthopanax divaricatus var. albeofructus (백모오가피로부터 분리된 트리터페노이드 및 리그난의 항산화작용)

  • 김지연;양기숙
    • YAKHAK HOEJI
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    • v.48 no.4
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    • pp.236-240
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    • 2004
  • Acanthopanax species (Araliaceae) traditionally has been used as analgesics, stimulant of immune system, and replenishment of body functions. Acanthopanax divaricatus var. albeofructus is indigenous plant to Korea. The antioxidant activities of compounds from A divaricatus var. albeofructus were determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) method and thiobarbituric acid reactive substance (TBARS) assay on human plasma low-density lipoprotein (LDL). The triterpenoid and lignan constituents from this plant showed antioxidant activities and the lignan, l-sesamin exhibited the most potent antioxidant activity in Cu$^{2+}$ -induced LDL oxidation.n.

NMR Techniques for the Structure Elucidation and Conformational Analysis of Natural Products

  • Cordell, Geoffrey A.
    • Korean Journal of Pharmacognosy
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    • v.19 no.3
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    • pp.153-169
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    • 1988
  • The combined use of the J-modulated selective INEPT and CSCM 1DNMR techniques is described for the structure elucidation of several new classes of compound including prionitin, the loureirins and larreantin, and for the regiosubstitution of the furanonaphthoquinones. Spectroscopic studies on the conformation of the cytotoxic agent savinin are also described, together with the NMR assignments and preliminary biosynthetic experiments on the antitumor antibiotic staurosporine.

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A New Furofuran Lignan from Geranium thunbergii Sieb. et Zuccc.

  • Liu, Qing-He;Jeong, Ji-Eun;Choi, Eun-Jin;Moon, Young-Hee;Woo, Eun-Rhan
    • Archives of Pharmacal Research
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    • v.29 no.12
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    • pp.1109-1113
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    • 2006
  • A new furofuran lignan, 4-hydroxykobusin (3), together with known lignans, kobusin (1), and 7,7'-dihydroxybursherenin (2), were isolated from the whole plant of Geranium thunbergii Sieb. et Zucc (Geraniaceae). The structures were determined based on the spectral data and a comparison with the published data. This is the first report of the presence of furofuran lignan in Geranium species.

The Chemistry of Secondary Products from Acanthopanax Species and their Pharmacological Activities

  • Shin, Kuk-Hyun;Lee, Sang-Hyun
    • Natural Product Sciences
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    • v.8 no.4
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    • pp.111-126
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    • 2002
  • The chemistry of secondary products from Acanthopanax species and their pharmacological activities were reviewed. A nitrogenous compound, a furan compound, a quinoid, benzoids, coumarins, phenylpropanoids, lignans, flavonoids, terpenoids, phytosterols, polyacetylenes, a pyrimidine, cyclitols, monosaccharides and an aliphatic alcohol have been isolated from Acanthopanax species and have been shown to have various levels of activities such as anti-bacterial, anti-cancer, anti-gout, anti-hepatitis, anti-hyperglycemic, anti-inflammatory, anti-leishmanicidic, anti-oxidant, anti-pyretic, anti-xanthine oxidase, choleretic, hemostatic, hypocholesterolemic, immunostimulatory and radioprotectant effects, etc.