Korean Journal of Pharmacognosy (생약학회지)
- Volume 19 Issue 3
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- Pages.153-169
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- 1988
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
NMR Techniques for the Structure Elucidation and Conformational Analysis of Natural Products
- Cordell, Geoffrey A. (Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago)
- Published : 1988.09.30
Abstract
The combined use of the J-modulated selective INEPT and CSCM 1DNMR techniques is described for the structure elucidation of several new classes of compound including prionitin, the loureirins and larreantin, and for the regiosubstitution of the furanonaphthoquinones. Spectroscopic studies on the conformation of the cytotoxic agent savinin are also described, together with the NMR assignments and preliminary biosynthetic experiments on the antitumor antibiotic staurosporine.
Keywords
- Structure elucidation;
- conformational analysis;
- biosynthesis;
- NMR techniques;
- lignans;
- alkaloids;
- diterpenes