• Journal of The Korean Ophthalmological Society
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• v.59 no.11
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• pp.1097-1102
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• 2018

Purpose: To report a case of toxic optic neuropathy caused by chlorfenapyr ingestion accompanied by central nervous system involvement. Case summary: A 44-year-old female visited our clinic complaining of reduced visual acuity in both eyes for 7 days. She had ingested a mouthful of chlorfenapyr for a suicide attempt 2 weeks prior to the visit. Gastric lavage was performed immediately after ingestion at the other hospital. Her best-corrected visual acuity was finger count 30 cm in the right eye and hand motion in the left eye. Both pupils were dilated by 5.0 mm and the response to light was sluggish in both eyes. A relative afferent pupillary defect was detected in her left eye. Funduscopy revealed optic disc swelling in both eyes. Magnetic resonance imaging of the brain showed a symmetric hyper-intense signal in the white matter tract including the internal capsule, corpus callosum, middle cerebellar peduncle, and brainstem. The patient was diagnosed with toxic optic neuropathy induced by chlorfenapyr ingestion, and underwent high-dose intravenous corticosteroid pulse therapy. Three days later, the best-corrected visual acuity was no light perception in both eyes. Three months later, optic atrophy was observed in both eyes. Optical coherence tomography revealed a reduction in the thicknesses of the retinal nerve fiber layer and ganglion cell and inner plexiform layer in the macular area. Conclusions: Ingestion of even a small amount of chlorfenapyr can cause severe optic nerve damage through the latent period, despite prompt lavage and high-dose steroid treatment.

• Journal of the Korea Convergence Society
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• v.10 no.1
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• pp.155-161
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• 2019

As composite is the light weight material whose durability and mechanical property are more superior than the existing general material. By taking notice of the composite with light weight, this study was about to investigate the static fracture characteristic of the bonded CFRP structure jointed with adhesive. Also, CFRP double cantilever beam with the variable of laminate angle was designed and the static fracture analysis was carried out. The laminate angles of CFRP double cantilever beam designed for this study were $30^{\circ}$, $45^{\circ}$ and $60^{\circ}$ individually. As the study result, the specimen with the laminate angle of $45^{\circ}$ was shown to have the durability better than those with the layer angles of $30^{\circ}$ and $45^{\circ}$. It was checked that the specimen with the laminate angle of $30^{\circ}$ had the weakest durability among all specimens. The damage data of the bonded CFRP structure by laminate angle could be secured through this study result. As the damage data of bonded interface obtained on the basis of this study result are utilized, the esthetic sense can be shown by being grafted onto the machine or structure at real life.

• Composites Research
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• v.37 no.3
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• pp.219-225
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• 2024

It is essential to develop a light-weight, high-performance structure for the deployable reflector antenna, which is the payload of a reconnaissance satellite, considering launch and orbital operation performance. Among them, the composite main reflector is a key component that constitutes a deployable reflector antenna. In particular, the development of a high-performance main reflector is required to acquire high-quality satellite images after agile attitude control maneuvers during satellite missions. To develop main reflector, the initial design of the main reflector was confirmed considering the structural performance according to the laminate stacking design and material properties of the composite main reflector that constitutes the deployable reflector antenna. Based on the initial design, four types of composite main reflectors were manufactured with the variable for manufacturing process. As variables for manufacturing process, the curing process of the composite structure, the application of adhesive film between the carbon fiber composite sheet and the honeycomb core, and the venting path inside the sandwich composite were selected. After manufacture main reflector, weight measurement, non-destructive testing(NDT), surface error measurement, and modal test were performed on the four types of main reflectors produced. By selecting a manufacturing process that does not apply adhesive film and includes venting path, for a composite main reflector with light weight and structural performance, we developed and verified a main reflector that can be applied to the SAR(Synthetic Aperture Rader) satellite.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.1
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• pp.117-123
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• 2002

To investigate the antiinflammatory and analgesic effects of Sophorae radix extracts administered to the arthritic rat model, immunohistochemical stains for CGRP in the L4, L5 and L6 spinal cord and ganglia were done, and paw swelling thickness were measured. Complete Freund,s Adjuvant(CFA) were injected to subcutaneous tissue of left foot paw of rats to induce arthritis. Sophorae radix extracts was administered immediately after CFA injection for 10 days. The spinal cord and ganglia were frozen sectioned(30㎛). These sections were stained by CGRP immunohistochemical staining method, and observed with light microscope. The results were as follows : 1. The change of paw swelling thickness of experimental group decreased from 4 day to 10day after CFA injection compared to control group. 2. The change of differential leukocytes counts of experimental group increased the ratio of lymphocytes. and decreased the ratio of neutrophils compared to control group. 3. The change of CGRP immunoreactive nerve fiber of dorsal horn of experimental group was dense stained compared to control group. 4. The number of CGRP immunoreactive neurons of L4 and L5 spinal cord of experimental group was less than in those control group. These results suggested that Sophorae radix extracts reduces the number of CGRP immunoreactive neurons and nerve fibers of spinal cord and ganglia, and decrease paw swelling thickness in arthritic rat model, which may be closely related to analgesic and antiinflammatory effects of Sophorae radix.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.52.3-53
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• 2015

The GMT-Consortium Large Earth Finder (G-CLEF) is a fiber-fed, optical band high dispersion echelle spectrograph that selected as the first light instrument for the Giant Magellan Telescope (GMT). This G-CLEF has been designed to be a general- purpose echelle spectrograph with the precisional radial velocity (PRV) capability of 10 cm/sec as a goal. The preliminary design review (PDR) was held on April 8 to 10, 2015 and the scientific observations will be started in 2022 with four mirrors installed on GMT. We have been participating in this preliminary design study in flexure control camera (slit monitoring system), calibration lamp sources, dichroic assembly and the fabrication of the proto-Mangin Mirror. We present the design concept on the parts KASI undertaken, introducing the specifications and capabilities of G-CLEF.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.24 no.2
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• pp.122-133
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• 2015

The requirements for the successful treatment of all-ceramic restorations are not so different from the ones of conventional restorations. "The provisional restoration followed by an adequate tooth reduction" and "the accurately fitting prostheses with corresponding to final impression" can be the examples of them. Nevertheless, the one which all-ceramic restorations are distinguished from conventional restorations is the additional procedure of so called "bonding". In addition to the application of resin cement between "inner surface of restoration and outer surface of abutment", bonding technology can be also applied to the treatment process of "Post and Core" in particular if the abutments are non-vital teeth. Core build-up for all-ceramic crown is conducted with fiber post and tooth colored composite by considering the properties of the restorations transmitting light. We know well that a vital abutment is easier than a non-vital one to get the targeted goals for clinical success in connection with esthetics and structure. The creation of "Post and Core" with bonding technique is a decisive factor for a long-term success if the abutment is non-vital tooth with dentinal collapse. I would like to share my clinical experience about "post & core build-up and all-ceramic restoration bonding" out of several success strategies of all-ceramic crown with this review article.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.16 no.3
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• pp.290-302
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• 1994

This study was aimed to clarify the histopathological changes in the experimental animal model subjcted to rigid fixation performed across the frontonasal sutrue in growing rabbits. Sixteen rabbits aged 6 weeks used. In experimental group(n=12), rigid fixation with miniplates and screws was performed across the frontonasal suture. Control group(n=4) was those with periosteal elevation only. Experimental animals were sacrificed on the 2nd, 4th, 8th, and 12th week after operation, and frontonasal suture area was excised for light microscopic and scanning electron microscopic examination. The results obtained were as follows : 1. In control groups, collagen fiber bundles ran in the midportion of bone sutrue and cambial layers were seen at bone surface. Sutural surfaces are beveled and external and internal bony projected portions were observed. 2. In experimental groups, distance of bone suture was decreased by new bone formation on the 2nd week, while increased by bone resorption at the miniplate applied area and bone formation in the adjacent bone on the 4th week. 3. In experimental groups, the original bone surface was almost resorbed and new bone formation was found on the 8th week. Regulary-run collagen fibers, smooth and dense bone surfaces were similar to the bone patterns of control groups on the 12th week. Above results suggest that bone formation is restricted where the miniplate is applied, while compensatory growth is appeared in the adjacent bont. It is considered that rigid fixation with miniplates and acrews results in a little disturbance of sutural growth of the craniofacial bone in infancy and children when applied for short duration.

• Composites Research
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• v.28 no.1
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• pp.15-21
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• 2015

The purpose of this paper is to investigate the current trends of composite applications in the marine and leisure fields and to study the development of 33ft class America's cup training CFRP sailing yacht. In the field of marine and leisure, composite materials have been just used to marine and leisure structures, recently. Especially, since the America's cup of sailing yacht racing has required the light weight and high mechanical performance to make a high speed, CFRP have been recognized as the critical material to construct the racing yacht structures. To establish the process of CFRP racing yacht construction, the design optimizations and production methods of carbon mast and CFRP yacht hull were discussed in this paper. Finally, the constructed CFRP sailing yacht exhibited high performance as the racing yacht through the sailing test.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.30 no.2
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• pp.52-58
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• 2002

Measurment of dynamic strain is important to monitor structural integrity. In this paper, the new type of EFPI is proposed to measure the dynamic strain. The second reflecting surface of fiber in this new sensor is deposited gold on to increase its reflectivity. So, it is called the gold-deposited EFPI (G-EFPI) in this paper. In order to explain the principle of measurement of the dynamic strain, two models for the loss of intensity are proposed and an experiment is performed. If a cavity between two reflecting surface increases, the loss of the light that passes through the cavity increases, causing a subsequent decrease in the output intensity of the sensor. Conversely, if the cavity decreases, the amount of loss decreases and the output intensity increases. Also the optimal length of the cavity is proposed to manufacture the G-EFPI with high sensitivity. Finally, the dynamic strainof a composite specimen was measured successfully using the G-EFPI.

• The Korea Journal of Herbology
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• v.20 no.4
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• pp.95-101
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• 2005

Objectives : In order to distinguish Cnidii Rhizoma and Ligustici Chuanxiong Rhizoma (cultivated in Korea and China), their external and internal states were observed via microscopic examination. Methods : The slice of the tested material made by paraffin section technique was colored with Safranine Malachite Green contrast methods, and then observed and photographed by olymphus-BHT. Results : Cnidii Rhizoma, Ligustici Chuanxiong Rhizoma (from Korea), and Ligustici Chuanxiong Rhizoma (from China) all demonstrated similar patterns as following : 1. external form 1) showing irregular nodular form with $2{\sim}7cm$ diameter. 2) having several trochites in parallel, and nodulose root trace on surface. 3) in addition to yellow-white or yellow-gray intersections, yellow-brown oil sacs were distributed, with cambium resembling a form of annulus. 2. internal form 1) its root and rhizome is composed of 10 layers of cork, with narrow cortical layers. 2) its phloem is wide, and oval light yellow-brown oil sacs are distributed around. The closer to the cambium, the smaller it is. 3) cambium is a form of a wave-like ring or an irregular polygon. 4) xylem and vessel are rare, most of which are arranged in a 'V' format, and sometimes xylem fiber is found. 5) pith is composed of parenchymatous cell, and parenchyma is full of starch grains. Conclusions : In conclusion, C officinale, L. chuanxiong (from Korea), and L. chuanxiong (from China) have rhizomes in a similar form with no special difference. Therefore, it is concluded that C. officinale, L. chuanxiong (from Korea), and L. chuanxiong (from China) are categorized into the same species.