• Journal of the Korea Institute of Military Science and Technology
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• v.20 no.3
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• pp.345-351
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• 2017

A wind tunnel test for the scaled parachute models was performed to verify aerodynamic characteristics for practical usage of Korean low cost low altitude aerial delivery system. The cruciform shaped cargo parachute models for heavy and light weight were ejected into wind tunnel test section; and the drag forces acting on the models in steady condition were measured in accordance with velocity. Also, the maximum opening forces during inflation were obtained and captured by a high speed camera to analyze the inflation characteristics and evaluate the design of the low cost aerial delivery system. The results showed a reliable stability and met the design requirement of delivery operation system for R.O.K Air Force.

• Polymer(Korea)
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• v.36 no.2
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• pp.149-154
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• 2012

The amphiphilic copolymer by the conjugation of biocompatible chitosan and antioxidant lipoic acid was studied as a drug delivery carrier. The amphiphilic copolymer was self-assembled to form nanoparticles in the aqueous solution. 5-Fluorouracil widely used as an anticancer drug was encapsulated inside the nanoparticles by a solid dispersion method. The degree of branching of lipoic acid on chitosan was controlled to obtain the optimal condition for the drug delivery carrier. The sizes of nanoparticles were about 250 nm by the dynamic light scattering. The encapsulation efficiency of nanoparticles were about 10%. The copolymer with 42% degree of branching showed the best performance as a drug delivery carrier.

• The Journal of the Korea institute of electronic communication sciences
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• v.7 no.5
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• pp.1079-1085
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• 2012

Many researchers worldwide have been making a lot of effort to find sustainable clean energy source to replace the current fossil fuels. However, solar energy is considered as the ultimate energy solution to supply the world total power consumption. Light can be used for lighting, heating, wired and wireless communications, etc. Moreover, even light-driven motors which can directly convert optical energy into kinetic energy are studied recently. In this paper, we analyze optical energy delivery through multi-core optical fibers. Our estimation shows that an optical power of 2 kW can be transmitted through a multi-core fiber and an optical power of >10 MW can be transmitted through a bundle of optical fibers with a diameter of several centimeters. It seems competitive compared with the electric power delivery through a copper cable.

• Journal of the Semiconductor & Display Technology
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• v.14 no.1
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• pp.45-49
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• 2015

Process gases with vapor or liquid phase as well as gas phase may experience alteration in itself or be contaminated in the fluid pipe to the process chamber. And thus it result in as particles or defects on the substrates in semiconductor, LCD, LED manufacturing. Purifiers and filters are used for control of contamination. However, none of detection device is available in the delivery line. In this paper, we propose simple device with lighting and sensing in order to predict contamination of the fluid or the tube wall. For some general purpose gases, it showed constant voltage output regardless of the flow rates. But, the smoke and the moisture in the air lowered the figure due to its concentration. Numerical values for several solid and liquid media were obtained. And, the operating temperature tendency was investigated.

• Journal of the Korean Applied Science and Technology
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• v.33 no.4
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• pp.667-675
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• 2016

Nanoemulsions are actively used in several applications for pharmaceutical, cosmetic and chemical industries. In this study, we propose the use of microfluidizer known as high pressure homogenizer to prepare lipid nanoemulsion as a potent cosmetic delivery carrier. The lipid nanoemulsions were prepared by O/W emulsion with hydrogenated lecithin and different type of oils. Effects of oil type on the stability of the lipid nanoemulsion were investigated with Dynamic Light Scattering (DLS) and Zeta-potential. Arbutin was used as model drug for transdermal administration through hairless mouse skin. Transdermal arbutin delivery using the lipid nanoemulsions was studied with HPLC method.

• Advances in materials Research
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• v.9 no.2
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• pp.109-114
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• 2020

The purpose of this study was to observe the trend of compounds release from acrylic resin oral prosthesis when used for drug delivery as well as a restoration. In this study, 10 specimens of heat-cured polymethylmethacrylate material were prepared and loaded with methylene blue biological stain. The specimens were then submerged in vials with 5 ml distilled water for 24 hours. The extraction procedure continued for 4 days, each day the specimens were immersed in another 5 ml distilled water vial. All extracted solutions were analyzed by visible light spectroscopy for absorbance comparison. The statistical results showed that the absorbance values were significantly different in the first day of extraction than the following days. However, there was no statistical difference among the 2^nd, 3^rd and 4^th days of extraction. Biological stain loading to acrylic resin at the mixing stage, and then after extraction in distilled water, showed a burst release during the first day followed by a constant release during the following few days.

• Journal of the Korean Society of Tobacco Science
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• v.24 no.1
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• pp.46-52
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• 2002

This study was carried out to investigate the transfer rate of I-menthol constituent into cigarette case and delivery rate to cigarette smoke. Test sample was used a light-type standard brand cigarette made in Korea. I-Menthol contents was measured according to A.O.A.C(1990) method by G.C and smoking conditions was a puff volume of 35$m\ell$ and 2.0s duration, taken once per minute to filter tipping paper plus 3mmwith 20 cigarettes. Migration rate of menthol into cigarette case had an interrelation with triacetin contents into filter and 6% triacetin level was most suitable. I-Menthol transferred to filter part from tobacco sheet by 20.2% in one month after cigarette manufacture, and the transfer was continued subsequently. Maximum menthol transfer in five months was 4.1% to foils and other packing materials and the loss outside of cigarette pack was also 3.9% below. The migration balance of menthol into cigarette pack and the delivery to cigarette smoke were the optimum condition when menthol was added at the ration of 30% in filter to 70% in the other parts into cigarette.

• Macromolecular Research
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• v.15 no.7
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• pp.646-655
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• 2007

To achieve targeted drug delivery for chemotherapy, a ligand-mediated nanoparticulate drug carrier was designed, which could identity a specific receptor on the surfaces of tumor cells. Biodegradable poly(ethylene oxide)/poly$({\varepsilon}-caprolactone)$ (PEG/PCL) amphiphilic block copolymers coupled to biotin ligands were synthesized with a variety of PEG/PCL compositions. Block copolymeric nanoparticles harboring the anticancer drug paclitaxel were prepared via micelle formation in aqueous solution. The size of the biotin-conjugated PEG/PCL nanoparticles was determined by light scattering measurements to be 88-118 nm, depending on the molecular weight of the block copolymer, and remained less than 120 nm even after paclitaxel loading. From an in vitro release study, biotin-conjugated PEG/PCL nanoparticles containing paclitaxel evidenced sustained release profiles of the drug with no initial burst effect. The biotin-conjugated PEG/PCL block copolymer itself evidenced no significant adverse effects on cell viability at $0.005-1.0{\mu}g/mL$ of nanoparticle suspension regardless of cell type (normal human fibroblasts and HeLa cells). However, biotin-conjugated PEG/PCL harboring paclitaxel evidenced a much higher cytotoxicity for cancer cells than was observed in the PEG/PCL nanoparticles without the biotin group. These results showed that the biotin-conjugated nanoparticles could improve the selective delivery of paclitaxel into cancer cells via interactions with over-expressed biotin receptors on the surfaces of cancer cells.

• Proceedings of the Korean Vacuum Society Conference
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• 2016.02a
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• pp.105.2-105.2
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• 2016

For the rational design and facile fabrication of novel nanostructures, we present a new approach to generating arrays of three-dimensionally tunable nanostructures by exploiting light-matter interaction. To create controlled three-dimensional (3D) nanostructures, we utilize the 3D spatial distribution of light, induced by the light-matter interaction, within the matter to be patterned. As a systematic approach, we establish 3D modeling that integrates the physical and chemical effects of the photolithographic process. Based on a comprehensive analysis of structural formation process and nanoscale features through this modeling, we are able to realize three-dimensionally tunable nanostructures using facile photolithographic process. Here we first demonstrate the arrays of three-dimensionally controlled, stacked nanostructures with nanoscale, tunable layers. We expect that the promising strategy would open new opportunities to produce the arrays of tunable 3D nanostructures using more accessible and facile fabrication process for various biomedical applications ranging from biosensors to drug delivery devices.

• Journal of the Korean Applied Science and Technology
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• v.15 no.4
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• pp.11-20
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• 1998

The propagation of light radiation in a turbid medium is an important problem that confronts dosimetry of therapeutic laser delivery and the development of diagnostic spectroscopy. Scattered light is measured as a function of the position(distance r, depth z) between the axis of the incident beam and the detection spot. Turbid sample yields a very forward-directed scattering pattern at short range of position from source to detector, whereas the thicker samples greatly attenuated the on-axis intensity at long range of position. The portions of scattered light reflected from or transmitted throughphantom depend upon internal reflectance and absorption properties of the phantom. Monte Carlo simulation method for modelling light transport in tissue is applied. It uses the photon is moved a distance where it may be scattered, absorbed, propagated, internally reflected, or transmitted out of tissue. The photon is repeatedly moved until it either escape from or is absorbed by the phantom. In order to obtain an optimum therapeutic ratio in phantom material, optimum control the light energy fluence rate is essential. This study is to discuss the physical mechanisms determining the actual light dose in phantom. Permitting a qualitative understanding of the measurements. It may also aid in designing the best model for laser medicine and application of medical engineering.