• Journal of the korean academy of Pediatric Dentistry
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• v.33 no.4
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• pp.615-623
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• 2006

The purpose of this study was to evaluate the specificity, sensitivity, and diagnostic power of caries activity test using LED fluorescence. The subjects of this study were 55 children of $6{\sim}7$ years old. LED light were irradiated to labial or buccal surface of all teeth. Fluorescence from initial carious lesion of teeth illuminated by an LED light was observed through barrier filter and the number of teeth showing lesion, size and position of lesion were counted. Streptococcus mutans colony counting and dDfFtT rate test were also done and their correlation was compared. And then specificity, sensitivity, diagnostic power of optical caries activity test using LED light were evaluated. 1. There was positive $correlation({\gamma}=0.43)$ between LED fluorescence test and Streptococcus mutans count(P<0.05). 2. When visual examination was defined to standard testing method, the specificity, sensitivity, diagnostic power of LED fluorescence test were 100%, 76.1%, and 100%. 3. When dDfFtT rate was defined to standard testing method, the specificity, sensitivity, diagnostic power of LED fluorescence test were 88.9%, 47.8%, and 95.7%. 4. When S. mutans colony counting was defined to standard testing method, the specificity, sensitivity, diagnostic power of LED fluorescence test were 100%, 58.7%, and 100%. Considering the above results, optical caries activity test using LED light could be regarded as a practical method because of its close relationship with microbiological caries activity test.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.05a
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• pp.283-286
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• 2002

In fiber optic sensor, the error of the measurement is influenced by the surface roughness of the target and surroundings, especially the outside light. To reduce or modify this error, the sensitivity of the fiber optic sensor and the noise change by the surface roughness of the target should be known. The purpose of this paper is to observe the sensitivity of the fiber optic sensor and the noise according to the surface roughness of the target.

• Communications of the Korean Mathematical Society
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• v.20 no.2
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• pp.311-319
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• 2005

In this paper we introduce a new class of parametric nonlinear implicit quasivariational inclusions and obtain some results about the existence and sensitivity analysis of solutions for this kind of quasivariational inclusions.

• Journal of Sensor Science and Technology
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• v.31 no.1
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• pp.1-5
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• 2022

In this paper, the photocurrent characteristics of gate/body-tied (GBT) metal-oxide semiconductor field-effect transistor (MOSFET)-type photodetector with high sensitivity in the 408 nm - 941 nm range are presented. High sensitivity is important for photodetectors, which are used in several scientific and industrial applications. Owing to its inherent amplifying characteristics, the GBT MOSFET-type photodetector exhibits high sensitivity. The presented GBT MOSFET-type photodetector was designed and fabricated via a standard 0.18 ㎛ complementary metal-oxide-semiconductor (CMOS) process, and its characteristics were analyzed. The photodetector was analyzed with respect to its width to length (W/L) ratio, bias voltage, and incident-light wavelength. It was confirmed experimentally that the presented GBT MOSFET-type photodetector has over 100 times higher sensitivity than a PN-junction photodiode with the same area in the 408 nm - 941 nm range.

• Science of Emotion and Sensibility
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• v.12 no.1
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• pp.1-10
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• 2009

The purpose of this study is to find out the relationship between the design factor and the sensitivity in web site. The classification of sensitivity-types consists of the research of books and the survey, and the language specialist's review and the analysis of factor. The research of the Image Scale accomplished through the analysis of the result of sensitivity-types. The major findings of the analysis are summarized as follows. The webpage sensitivity-types are classified into the 7 types, namely 'refreshment', 'calm', 'refinement', 'strongness', 'youth', 'uniqueness', 'futurity'. As a result of analyzing of similarity between the adjectives by multiple standards, the web site Image Scale space consists of the axis between 'heavy-light' and 'soft-hard'. As a result of the research of relationship between the web site design factor and the emotion, the color and the layout influenced into 'soft-hard' much, and the light and the color influenced into 'heavy-light' much.

• Journal of Photoscience
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• v.9 no.2
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• pp.454-456
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• 2002

It is important to determine the action spectrum of UV-B radiation contained in the sunlight to estimate the risk of skin cancer. We have investigated action spectra for induction of apoptosis and reproductive cell death in L5178Y cells using the Okazaki Large Spectrograph at NIBB. L5178Y cells were exposed to light at different wavelengths in UV-B or UV-A region. Frequencies of apoptosis induction and reproductive cell death were determined by counting cells with chromatin condensation, and by the colony formation assay, respectively. The measured sensitivity spectra for the two end-points were in very good agreement. Sensitivity decreased steeply with increase of wavelength in UV-B region and remains nearly constant in UV-A region. The action spectra were also slightly steeper than that for the minimum erythematic dose (MED), but very similar to the light absorption spectrum of DNA in UV-B region. On the other hand, the spectra for both endpoints were similar to MED spectrum but not DNA spectrum in the UV-A region. Also different time-course and morphological difference of apoptosis were found between UV-B (long time, fragmentation) and UV-A (short time, shrinkage) region. These results suggest that DNA damage induced by UV-B light triggers apoptosis and reproductive cell death, but other damaged targets (membrane, protein and so on) trigger these effects in UV-A region.

• Korean Journal of Clinical Laboratory Science
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• v.43 no.2
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• pp.33-42
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• 2011

Zinc plays a key role in genetic expression, cell division, and cell growth and is essential for the functions of more than 450 metalloenzyme. There are high concentrations of zinc in pigment epithelium in bullfrog eye. Zinc deficiency causes night blindness and abnormal dark adaptation. The purpose of this study was to identify ERG (electroretinogram) b-wave sensitivity during light and dark adaptation in bullfrog retina after zinc and zinc chelators treatment such as histidine and TSQ (N-(6-methoxy-8-qunolyl)-p-toluenesulfon amide). Especially, we focused whether histidine act as a zinc chelator in the Muller cell. The results of our study are summarized as follows: 1) Both zinc and histidine elevated ERG b-wave amplitude and threshold in Muller cells by accelerating rhodopsin regeneration time and increased a-peak absorbance during light adaptation. 2) TSQ reduced those by prolonging rhodopsin regeneration time and decrement of a-peak absorbance during light adaptation. 3) Zinc shortened rhodopsin regeneration time and prolonged a-peak absorbance. These results suggested that histidine may act as a zinc-mediated transporter in presynaptic Muller cell membrane rather than zinc chelator and acts as a GABA-receptor inhibitor which blocks $Cl^-$ influx to the postsynapse.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.377-377
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• 2007

A simplified integration process including packaging is presented, which enables the realization of the portable fluorescence detection system. A fluorescence detection microchip system consisting of an integrated PIN photodiode, an organic light emitting diode (OLED) as the light source, an interference filter, and a microchannel was developed. The on-chip fluorescence detector fabricated by poly(dimethylsiloxane) (PDMS)-based packaging had thin-film structure. A silicon-based integrated PIN photo diode combined with an optical filter removed the background noise, which was produced by an excitation source, on the same substrate. The active area of the finger-type PIN photo diode was extended to obtain a higher detection sensitivity of fluorescence. The sensitivity and the limit of detection (LOD S/N = 3) of the system were $0.198\;nA/{\mu}M$ and $10\;{\mu}M$, respectively.

• Proceedings of the Optical Society of Korea Conference
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• 1999.08a
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• pp.156-157
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• 1999

• Korean Journal of Optics and Photonics
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• v.32 no.3
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• pp.126-132
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• 2021

In this research, we have investigated the sensitivity of an extraordinary optical transmission sensor depending on the angle of incident light. Three types of light, including a collimated beam and focused beams (4× and 10×), were designed for the sensor system. To compare the sensitivity of the sensor, we measured transmittance spectra using deionized water (n=1.333) and refractive-index-matching oils (n=1.360 and 1.380). Those spectra were analyzed in terms of redshifting of the peak, so that we could determine the sensitivity. The sensitivity tended to increase when the collimated beam is used on the system, and we have concluded that the sensitivity could be affected by the incidence angle on an extraordinary optical transmission sensor.