• Title/Summary/Keyword: Light Sensitivity

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Design of Integrated-Optic Biosensor Based on the Evanescent-Field and Two-Horizontal Mode Power Coupling of Si3N4 Rib-Optical Waveguide (Si3N4 립-광도파로의 두-수평모드 파워결합과 소산파 기반 집적광학 바이오센서 설계)

  • Jung, Hongsik
    • Journal of Sensor Science and Technology
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    • v.29 no.3
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    • pp.172-179
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    • 2020
  • We studied an integrated-optic biosensor configuration that operates at a wavelength of 0.63 ㎛ based on the evanescent-wave and two horizontal mode power coupling of Si3N4 rib-optical waveguides formed on a Si/SiO2/Si3N4/SiO2 multilayer thin films. The sensor consists of a single-mode input waveguide, followed by a two-mode section which acts as the sensing region, and a Y-branch output for separating the two output waveguides. The coupling between the two propagating modes in the sensing region produces a periodically repeated optical power exchanges along the propagation. A light power was steered from one output channel to the other due to the change in the cladding layer (bio-material) refractive index, which affected the effective refractive index (phase-shift) of two modes through evanescent-wave. Waveguide analyses based on the rib optical waveguide dimensions were performed using various numerical computational software. Sensitivity values of 12~23 and 65~165 au/RIU, respectively for the width and length of 4 ㎛, and 3841.46 and 26250 ㎛ of the two-mode region corresponding to the refractive index range 1.36~1.43 and 1.398~1.41, respectively, were obtained.

Sensitivity improvement of $CeO_2$ oxygen sensor by betterment of surface characteristics through chemical mechanical polishing process (CMP 공정을 통한 표면 특성 개선에 의한 $CeO_2$ 산소 센서 감도 향상 연구)

  • Jung, Pan-Gum;Jun, Young-Kil;Ko, Pil-Ju;Kim, Nam-Hoon;Lee, Woo-Sun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.11a
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    • pp.65-65
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    • 2007
  • Microstructure and surface roughness of the sensing materials should be improved to use them in advanced sensor applications because the uneven surface roughness degrades the light reflection, pattern resolution, and devices performance. Chemical mechanical polishing (CMP) processing was selected for improving the surface roughness of $CeO_2$ which is one of the well known materials for the oxygen gas sensors. Surface roughness and removal rate of spin coated $CeO_2$ thin films were examined with a change of CMP process parameters such as down force and table speed. The optimized process condition, reflected by the surface roughness with the hillock-free surface as well as the excellent removal rate with the good uniformity, was obtained. The effects of the improved surface roughness on the sensing property of $CeO_2$ thin films were also confirmed. The improved sensitivity of $CeO_2$ thin films for oxygen sensors were obtained after CMP process by the improved surface characteristics. Therefore, we conclude that sensing property of $CeO_2$ thin film is strongly dependent on the surface roughness of $CeO_2$ thin films by using CMP process.

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pH-Sensitivity Control of PEG-Poly(${\beta}$-amino ester) Block Copolymer Micelle

  • Hwang, Su-Jong;Kim, Min-Sang;Han, Jong-Kwon;Lee, Doo-Sung;Kim, Bong-Sup;Choi, Eun-Kyung;Park, Heon-Joo;Kim, Jin-Seok
    • Macromolecular Research
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    • v.15 no.5
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    • pp.437-442
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    • 2007
  • Poly(ethylene glycol) methyl ether (PEG)-poly(${\beta}$-amino ester) (PAE) block copolymers were synthesized using a Michael-type step polymerization, and the construction of pH-sensitive polymeric micelles (PM) investigated. The ${\beta}$-amino ester block of the block copolymers functioned as a pH-sensitive moiety as well as a hydrophobic block in relation to the ionization of PAE, while PEG acted as a hydrophilic block, regardless of ionization. The synthesized polymers were characterized using $^1H-NMR$, with their molecular weights measured using gel permeation chromatography. The $pK_b$ values of the pH-sensitive polymers were measured using a titration method. The pH-sensitivity and critical micelle concentration (CMC) of the block copolymers in PBS solution were estimated using fluorescence spectroscopy. The pH dependent micellization behaviors with various bisacrylate esters varied within a narrow pH range. The critical micelle concentration at pH 7.4 decreased from 0.032 to 0.004 mg/mL on increasing the number of methyl group in the bisacrylate from 4 to 10. Also, the particle size of the block copolymer micelles was determined using dynamic light scattering (DLS). The DLS results revealed the micelles had an average size below 100 nm. These pH-sensitive polymeric micelles may be good carriers for the delivery of an anticancer drug.

Chilling Tolerance of Photosynthesis in Plants is Dependent on the Capacity to Enhance the Levels of the Xanthophyll Cycle Pigments in Response to Cold Stress

  • Kim, Hyun-Ju;Kang, In-Soon;Lee, Chin-Bum;Lee, Choon-Hwan;Cho, Sung-Ho;Moon, Byoung-Yong
    • Journal of Photoscience
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    • v.12 no.1
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    • pp.33-39
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    • 2005
  • Plants possess the ability to dissipate the excitation energy for the protection of photosynthetic apparatus from absorbed excess light. Heat dissipation is regulated by xanthophyll cycle in thylakoid membranes of chloroplasts. We investigated the mechanistic aspects of xanthophyll cycle-dependent photoprotection against low-temperature photoinhibition in plants. Using barley and rice as chilling-resistant species and sensitive ones, respectively, chilling-induced chlorophyll fluorescence quenching, composition of xanthophyll cycle pigments and mRNA expression of the zeaxanthin epoxidase were examined. Chilled barley plants exhibited little changes in chlorophyll fluorescence quenching either of photochemical or non-photochemical nature and in the photosynthetic electron transport, indicating low reduction state of PS II primary electron acceptor. In contrast to the barley, chilled rice showed a marked decline in those parameters mentioned above, indicating the increased reduction state of PS II primary electron acceptor. In addition, barley plants were shown to have a higher capacity to elevate the pool size of xanthophyll cycle pigments in response to cold stress compared to rice plants. Such species-dependent regulation of xanthophyll cycle activity was correlated with the gene expression level of cold-induced zeaxanthin epoxidase. Chilled rice plants depressed the gene expression of zeaxanthin epoxidase, whereas barley increased its expression in response to cold stress. We suggest that chilling-induced alterations in the pool size of xanthophyll cycle pigments related to its capacity would play an important role in regulating plant's sensitivity to chilling stress.

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Simulation Studies for Noninvasive Optical Measurements of Blood-Scattering Changes in a Skin Model with a Large Blood Vessel

  • Zephaniah, Phillips V;Paik, Seung-ho;Nam, Jungyong;Chang, Ki Young;Jung, Young-Jin;Choi, Youngwoon;Lee, Joonhyung;Kim, Beop Min
    • Current Optics and Photonics
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    • v.3 no.1
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    • pp.46-53
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    • 2019
  • Monte Carlo simulations were performed for a three-dimensional tissue model with and without an embedded large vessel, to understand how varying vessel geometry affects surface light distribution. Vessel radius was varied from 1 to 5 mm, and vessel depth from 2 to 10 mm. A larger difference in surface fluence rate was observed when the vessel's radius increased. For vessel depth, the largest difference was seen at a depth of approximately 4 mm, corresponding to human wrist region. When the vessel was placed at depths greater than 8 mm, very little difference was observed. We also tested the feasibility of using two source-detector pairs, comprising two detectors distinctly spaced from a common source, to noninvasively measure blood-scattering changes in a large vessel. High sensitivity to blood-scattering changes was achieved by placing the near detector closer to the source and moving the far detector away from the source. However, at longer distances, increasing noise levels limited the sensitivity of the two-detector approach. Our results indicate that the approach using two source-detector pairs may have potential for quantitative measurement of scattering changes in the blood while targeting large vessels near the human wrist region.

Effects of Fully Filling Deep Electron/Hole Traps in Optically Stimulated Luminescence Dosimeters in the Kilovoltage Energy Range

  • Chun, Minsoo;Jin, Hyeongmin;Lee, Sung Young;Kwon, Ohyun;Choi, Chang Heon;Park, Jong Min;Kim, Jung-in
    • Journal of Radiation Protection and Research
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    • v.47 no.3
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    • pp.134-142
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    • 2022
  • Background: This study investigated the characteristics of optically stimulated luminescence dosimeters (OSLDs) with fully filled deep electron/hole traps in the kV energy ranges. Materials and Methods: The experimental group consisted of InLight nanoDots, whose deep electron/hole traps were fully filled with 5 kGy pre-irradiation (OSLDexp), whereas the non-pre-irradiated OSLDs were arranged as a control group (OSLDcont). Absorbed doses for 75, 80, 85, 90, 95, 100, and 105 kVp with 200 mA and 40 ms were measured and defined as the unit doses for each energy value. A bleaching device equipped with a 520-nm long-pass filter was used, and the strong beam mode was used to read out signal counts. The characteristics were investigated in terms of fading, dose sensitivities according to the accumulated doses, and dose linearity. Results and Discussion: In OSLDexp, the average normalized counts (sensitivities) were 12.7%, 14.0%, 15.0%, 10.2%, 18.0%, 17.9%, and 17.3% higher compared with those in OSLDcont for 75, 80, 90, 95, 100, and 105 kVp, respectively. The dose accumulation and bleaching time did not significantly alter the sensitivity, regardless of the filling of deep traps for all radiation qualities. Both OSLDexp and OSLDcont exhibited good linearity, by showing coefficients determination (R2) > 0.99. The OSL sensitivities can be increased by filling of deep electron/hole traps in the energy ranges between 75 and 105 kVp, and they exhibited no significant variations according to the bleaching time.

Analysis of the first core of the Indonesian multipurpose research reactor RSG-GAS using the Serpent Monte Carlo code and the ENDF/B-VIII.0 nuclear data library

  • Hartanto, Donny;Liem, Peng Hong
    • Nuclear Engineering and Technology
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    • v.52 no.12
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    • pp.2725-2732
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    • 2020
  • This paper presents the neutronics benchmark analysis of the first core of the Indonesian multipurpose research reactor RSG-GAS (Reaktor Serba Guna G.A. Siwabessy) calculated by the Serpent Monte Carlo code and the newly released ENDF/B-VIII.0 nuclear data library. RSG-GAS is a 30 MWth pool-type material testing research reactor loaded with plate-type low-enriched uranium fuel using light water as a coolant and moderator and beryllium as a reflector. Two groups of critical benchmark problems are derived on the basis of the criticality and control rod calibration experiments of the first core of RSG-GAS. The calculated results, such as the neutron effective multiplication factor (k) value and the control rod worth are compared with the experimental data. Moreover, additional calculated results, including the neutron spectra in the core, fission rate distribution, burnup calculation, sensitivity coefficients, and kinetics parameters of the first core will be compared with the previous nuclear data libraries (interlibrary comparison) such as ENDF/B-VII.1 and JENDL-4.0. The C/E values of ENDF/B-VIII.0 tend to be slightly higher compared with other nuclear data libraries. Furthermore, the neutron reaction cross-sections of 16O, 9Be, 235U, 238U, and S(𝛼,𝛽) of 1H in H2O from ENDF/B-VIII.0 have substantial updates; hence, the k sensitivities against these cross-section changes are relatively higher than other isotopes in RSG-GAS. Other important neutronics parameters such as kinetics parameters, control rod worth, and fission rate distribution are similar and consistent among the nuclear data libraries.

Study on the Screening of the $SO_2$ Resistant Species for Landscape in Air Polluted Area (대기오염지역(大氣汚染地域) 조경용(造景用) 수종(樹種)의 개발(開發)을 위(爲)한 $SO_2$에 대한 내연성(耐煙性) 비교(比較) 연구(硏究))

  • Lim, Soo-Kil;Lee, Joong-Bae
    • Korean Journal of Environmental Agriculture
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    • v.12 no.2
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    • pp.153-161
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    • 1993
  • This study was conducted to compare the resistance and sensitivity of trees with 6 native species exposing to 4 different levels of $SO_2$gas(0.4, 0.7, 1.5 and 3.0 ppm) respectively. The results are summarized as follows : 1. Visible injuries appeared as spots in the region of intervein on the leaves for all the species and the color of the spots changed from light green and/or brown to light brown, dark brown, and/or redish brown. 2. The sensitivity of the species to $SO_2$ was high in the descending order of Zizyphus jujuba, Cataegus pinnatifida, Viburnum sargentii, Weigela subsessilis, Euonymus japonica, and Acer ginnala. 3. The resistance of the species to $SO_2$ was high in the descending order of Acer ginnala, Eunymus japonica Viburnum sargentii, Weigela subsessilis, Zizyphus jujuba, and Crataegus pinnatifida. 4. When the trees were exposed to $SO_2$gas, the contents of chlorophyll a, b, and a+b were consostently lower than those of control, and water soluble sulfur contents in the leaves were higher than those of control. 5. There was no significant correlation between stomatal resistance and the sensitivity(or resistance) of the trees exposed to $SO_2$ gas. 6. In this study, it was concluded that Acer ginnala was more suitable species than the others for landscape in air polluted area because it showed high resistance, low sensitivity, and low stromal resistance to $SO_2$gas exposure.

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Water Physiology of Panax ginseng. 1. Habitat observation. cultural experience, weather factors and characteristics of root and leaf (인삼의 수분생리 1. 자생지관찰.재배 경험.기상요인과 근 및 엽의 특성)

  • Park, Hoon
    • Journal of Ginseng Research
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    • v.4 no.2
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    • pp.197-221
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    • 1980
  • Habitat observation, cultural experience of old and present plantation, weather factors in relation to crop stand and water physiology of root and leaf were reviewed. According to habitat observation ginseng plants love water but plate wit talus well grow at drained place with high moisture content in air and soil while ginseng plants were not found in dry or wet place. According to cultivation experience ginseng plants require abundant water in nursery and main field but most old planters believe that ginseng plaints are draught-loving thus require little water. The experience that rain especially in summer i.e unfavorable might be due to mechanical damage of leaves arid leaf disease infection, or severe leaf fall which is caused by high air temperature and coinsided with rain. According to crop stand observation in relation to weather factors abunsant water increased each root weight but decreased total yield indicating tile increase of missing root rate. Rain in summer was unfavorable too. Though rain in June was favorable for high yield general experience that cloudy day and rain were unfavorable might be due to low light intensity under shade. Present leading planters also do loot consider the importance of water in main field. Water content is higher in top than in root and highest in central portion of root and in stem of top. For seedling the heavier the weight of root is tile higher the water content while it reveries from two years old. Water potential of intact root appeared to be -2.89 bar suggesting high sensitivity to water environment. Under water stress water content severly decreased only in leaf. Water content of leaf appeared to be 78% for optimum, below 72% for functional damage and 68% for perm anent wilting. Transpiration or curs Principally through stomata in lower side of leaf thus contribution of upper side transpiration decreased with the increase of intensity. Transpiration is greater in the leaves grown under high light intensity. Thus water content is lower with high light inte nsity under field condition indicating that light is probable cause of water stress in field. Transpiration reached maximum at 10K1ut The decrease of transpiration at higher temperature seems to be due to the decrease of stomata aperture caused by water stress. Severe decrease of photosynthesis under water stress seems to be principally due to functional damage which is not caused by high temperature and Partly due to poor CO2 supply. Water potential of leaf appeared to be -16.8 bar suggesting weakness in draught tolerance. Ginseng leaves absorb water under high humidity. Water free space of leaf disc is %mailer than that of soybean leaf and water uptake appears to be more than two steps.

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Usefulness of Color-overlay Pattern of Breast Elastic Ultrasonography (유방 탄성초음파의 Color overlay pattern에 대한 유용성)

  • An, Hyun;Im, In-Chul
    • Journal of the Korean Society of Radiology
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    • v.11 no.5
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    • pp.401-406
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    • 2017
  • Breast cancer rates are increasing every year, biopsy for diagnosing breast cancer is increasing as well. Biopsy also invasive test, have bad side effects from patients anxiety, infection, bleeding. In this study, Conduct a survey of 69 patients who brest lesion patient, both B-mode ultrasound and elastography exam and B-mode ultrasound was classified according to the BI-RADS category, and the elastography exam was classified according to the Color overlay pattern that the value of the kPa expressed in relation to the propagation velocity of Transverse waves. The optimal cut off value of the highest sensitivity and specificity was 54.70 kPa. In the color overlay pattern, Dark Blue 42 people, Light blue ~ Red 27 people classified results and BI-RADS classification results, benign 40 people and malignant 29 people classified results showed similar results. Therefore, It is judged that the color overlay pattern is positive when classified into Dark Blue, and malignant when classified into Light blue ~ Red. In conclusion, breast elastography is expected to play a innovative role in reducing the number of breast cancer examinations and classify between benign and malignant tumor.