• Title/Summary/Keyword: Life-forms

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Placement of a Subclavian Tunneled Hemodialysis Catheter with the Patient's Arm Raised May Reduce the Risk of Complications: Two Cases Report (쇄골하정맥을 통한 매립혈액투석카테터 삽입시 상지 거상법의 유용성: 2예 보고)

  • Jimin Yoo;Dong Jae Shim;Doyoung Kim;Seung Hwan Baek;Chang Suk Park;Jeong Whee Lee
    • Journal of the Korean Society of Radiology
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    • v.84 no.2
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    • pp.477-482
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    • 2023
  • The subclavian vein is an uncommon route for tunneled hemodialysis catheter (tHDC) placement because of its potency for future dialysis access. However, when favored access routes have been exhausted because of repeated catheterization or limited life expectancy, the subclavian vein can be used for urgent hemodialysis. A subclavian catheterization has a technical problem. The subclavian vein often forms a right angle with the vena cava, and advancing stiff peel-away sheath can cause a vascular injury. However, raising the patient's arm can alter the position of the guidewire and, therefore, change the angle of the vein favorable for tHDC placement. Herein, we report two patients who underwent subclavian catheterization; one experienced an injury to the superior vena cava after undergoing the conventional procedure, whereas the other patient with raised arm during the catheterization procedure had safe catheter placement.

Seeking Alternative Directions in Confirmation Education for Korean Protestant Church (한국교회 견신례 교육의 대안적 방향에 관한 연구)

  • Shin-Geun Jang
    • Journal of Christian Education in Korea
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    • v.75
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    • pp.7-31
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    • 2023
  • Purpose of study: The purpose of this essay is to seek an alternative direction for confirmation education within the context of Korean Protestant Church, addressing the following issues: 1) Confusion in the use of terminology on confirmation, 2) Superficial understanding of confirmation, and the absence or privatization of confirmation theology, 3) Formalized confirmation education based on the concept of rites of passage, and 4) The absence of denominationally structured confirmation education. Research content and method: To achieve this purpose, this essay attempts to foster an intradisciplinary and interactive dialogue on confirmation through a biblical, historical, and theological approach. Biblically, confirmation is to be understood as the unity of the baptism of water and the baptism of Holy Spirit, associated with the consecration of the baptized as royal priests through the baptism of Holy Spirit. Historically, as a part of the rite of Christian initiation, confirmation was a unified rite that has undergone a process of separation and reunification. Theologically, the rite of confirmation affirms the covenant of the Triune God given in baptism and is positioned between baptism and the Lord's Supper. Conclusions and Suggestions: In conclusion, this essay suggests an alternative form of Confirmation education that is oriented towards the following objectives: 1) Education that forms the identity given in the baptismal covenant, 2) Education that reflects characteristics of both baptism and the Lord's Supper, 3) Education that integrates the Bible, doctrine, and life of confirmand and, 4) Education based on an organic educational system.

Evaluating the Impact of Walkability Environments on Leisure Walking Using Google Street View and Deep Learning - A Case Study of Yongsan District, Seoul - (구글 스트리트 뷰와 딥러닝을 활용한 보행 친화적 환경이 여가보행에 미치는 영향 평가 - 서울특별시 용산구를 대상으로 -)

  • Lee, Da-Yeon;Lee, Ji-Yun;Lee, Jae Ho
    • Journal of the Korean Institute of Landscape Architecture
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    • v.52 no.4
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    • pp.45-55
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    • 2024
  • This study aims to distinguish between utilitarian walking and leisure walking activities and analyze the correlation between these types of walking and the walking environment. To measure the walking environment, we utilized Google Street View (GSV) and employed semantic segmentation deep learning techniques to quantitatively assess urban walking environment elements as perceived by pedestrians. A survey was conducted to measure utilitarian walking, leisure walking, and perceived walking environment satisfaction, collecting valid responses from 192 participants. Using the survey data, we visualized utilitarian walking, leisure walking, and perceived walking environment satisfaction, and analyzed the correlation between these variables and the walkability scores. The results indicated that leisure walking had a significant positive correlation with walkability (Pearson's r = 0.121, p-value = 0.012), while there was no significant correlation between utilitarian walking and walkability (Pearson's r = 0.093, p-value = 0.055). These findings suggest that people prioritize mobility efficiency over the walking environment for utilitarian walking, whereas the quality of the walking environment significantly influences the frequency of leisure walking. Based on these results, the study proposes specific strategies to improve the walking environment around residential areas to promote leisure walking. These strategies include creating vertical gardens or various forms of three-dimensional gardens on narrow walkways and improving sidewalk design. The findings of this study can contribute to promoting leisure walking by creating walk-friendly environments, ultimately enhancing urban sustainability and the quality of life for residents.

Fruit Characteristics of the Secondary Bearing Shoots of Blueberry 'Scintilla' Grown in a Heated Greenhouse (가온 하우스 재배 블루베리 '신틸라'에 있어서 2차 결과지의 과실 특성)

  • Mi Geon Cheon;Kyung Mi Park;Sang Woo Choi;Seong-Tae Choi;Hye Suk Yoon;Weong Gwang Kim;Jin Gook Kim
    • Journal of Bio-Environment Control
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    • v.32 no.4
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    • pp.336-341
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    • 2023
  • This study examines the characteristics of berries from secondary bearing shoots of 'Scintilla' southern highbush blueberry, grown hydroponically in the Jinju, Gimhae, and Uiryeong regions of Gyeongnam Province. Typically, 'Scintilla' forms flower buds at the tips of regular bearing shoots during the previous season, yielding berries in the current season. However, under heated cultivation, we observed a proliferation of secondary bearing shoots that produce berries in the same growing season. Flowering and harvesting on secondary bearing shoots were delayed by 52 and 36 days, respectively, compared to regular bearing shoots. However, these shoots exhibited a 54% increase in diameter and a 10% increase in length. We found no significant difference in berry size and soluble solid content between the two types of shoots. Notably, berries from the secondary bearing shoots had higher potassium and lower calcium and magnesium concentrations. We conclude that berries from secondary bearing shoots could be marketable, provided the bushes are healthy. These findings provide valuable insights for optimizing cultural practices to improve the yield and quality of blueberries under specific environmental conditions.

Expression Properties and Skin Permeability of Human Basic Fibroblast Growth Factor with or without PTD Fused to N- or C-terminus in Escherichia coli (대장균 발현시스템에서 단백질 전달 도메인 PTD가 인간 섬유아세포 성장인자(FGF2)의 N- 또는 C-말단에 결합 되었을 때 미치는 재조합 단백질 복합체의 발현 특성과 피부 투과능력)

  • Park, In-Sun;Choe, Chung-Hyeon;Kwon, Bo-Ra;Choi, Young-Ji;Kwon, Tae-Ho;Yu, Kang-Yeol;Lee, Juhyung;Choo, Young-Moo
    • Journal of Life Science
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    • v.28 no.3
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    • pp.275-283
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    • 2018
  • Human fibroblast growth factor (FGF) has the potential to be a commercially important therapeutic or cosmeceutical agent due to its ability to generate tissue and heal wounds. Granting permeability into skin tissues increases the therapeutic effects of FGF. Thus, several researchers have attempted the fusion of FGF conjugates with protein transduction domains (PTDs) to investigate the transduction ability and therapeutic effects of FGF. Less is known, however, about whether the location of PTD fused to the N- or C-terminus of FGF proteins has a significant impact on the folding and stability in Escherichia coli, and eventually, on transduction. Here, we report cloning of human basic fibroblast growth factor (FGF2) as a control and FGF2 with PTD fused to the N- or C-terminal ends of FGF proteins by an overlap extension PCR. We performed expression, verified expression properties of recombinant FGF2 without or with PTD fused to the N-terminus and the C-terminus, and investigated transduction ability into tissue by treating the dorsal skin of mice subjects. As a result, FGF2 and FGF2-PTD (fused to C-terminus) fusion protein were expressed as soluble forms suitable for straight-forward purification, unlike insoluble PTD-FGF2 (fused to N-terminus), but only FGF2-PTD fusion protein could transduce into the dorsal skin tissue of the mice subjects. Our results suggest that FGF2 with PTD fused to the C-terminus is more efficient than other options in terms of expression, purification, and delivery into skin tissue, as it does not require labor-intensive, costly, and time-consuming methods.

Ultrastructure of the Integument of Capillaria hepatica (syn. Calodium hepatica) (간모세선충(Capillaria hepatica) 표피의 미세구조)

  • Kim, Soo-Jin;Min, Byoung-Hoon;Lee, Haeng-Sook;Lee, Byoung-Wook;Joo, Kyoung-Hwan
    • Applied Microscopy
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    • v.39 no.2
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    • pp.167-173
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    • 2009
  • Capillaria hepatica is a parasitic nematode which causes hepatic capillariasis in rodents and other mammals, including man. Rat species of the genus Rattus are main primary host and rates of genus Rattus of up to 100% have been reported. Infection to reservoir and other mammalian hosts occur incidentally due to ingestion of water or food contaminated with C. hepatica embryonated eggs. The worms mature exclusively inside the liver, but they die and disassemble soon after egg spawning in rats. Dead worms and their eggs cause immune response of focal necrosis and inflammation within the liver. C. hepatica adult with a thin and long body is similar to capillary. The members of Order Trichurida are characterized by having a stichosome and the bacillary bands in front of the body. As already mentioned, the adult C. hepatica residesin the liver, where it deposits groups of eggs, and finally die in the encapsulated tissue of the liver. They produce eggs that elicit a marked granulomatous reaction that eventually destroy the worms. And the adult worms were mixed with eggs. So the complete isolation of the worm and observation of intact ultrastructure is very difficult. In this study, integument structure of C. hepatica isolated from the liver of mouse at 7 weeks after inoculation of embryonated eggs were observed with scanning and transmission electron microscopy. As a results, body length of isolated C. hepatica was about 99 mm. Cuticle, bacillary band and bacillary pore were obtained in the integument of worm. Bacillary pore across cuticular surface of the worm were observed. According to the existence of cap material, external forms of bacillary pore can be divided into three types such as flat, ingression, and ingression with the cap material type. The complete isolation of the worm and observation of ultrastructure of integument will provide the fundamental data which is important in the nematode research including C. hepatica.

Oxidative Stress-dependent Structural and Functional Regulation of 2-cysteine Peroxiredoxins In Eukaryotes Including Plant Cells (산화 스트레스에 의존한 식물 및 진핵세포 2-시스테인 퍼록시레독신의 기능 조절)

  • Jang, Ho-Hee;Kim, Sun-Young;Lee, Sang-Yeol
    • Journal of Plant Biotechnology
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    • v.33 no.1
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    • pp.1-9
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    • 2006
  • Peroxiredoxins (Prxs) are ubiquitously distributed and play important functions in diverse cellular signaling systems. The proteins are largely classified into three groups, such as typical 2-Cys Prx, atypical 2-Cys Prx, and 1-Cys Prx, that are distinguished by their catalytic mechanisms and number of Cys residues. From the three classes of Prxs, the typical 2-Cys Prx containing the two-conserved Cys residues at its N-terminus and C-terminus catalyzes $H_2O_2$ with the use of thioredoxin (Trx) as an electron donor. During the catalytic cycle, the N-terminal Cys residue undergoes a peroxide-dependent oxidation to sulfenic acid, which can be further oxidized to sulfinic acid at the presence of high concentrations of $H_2O_2$ and a Trx system containing Trx, Trx reductase, and NADPH. The sulfinic acid form of 2-Cys Prx is reduced by the action of sulfiredoxin which requires ATP as an energy source. Under the strong oxidative or heat shock stress conditions, 2-Cys Prx in eukaryotes rapidly switches its protein structure from low-molecular-weight species to high-molecular-weight protein structures. In accordance with its structural changes, the protein concomitantly triggers functional switching from a peroxidase to a molecular chaperone, which can protect its substrate denaturation from external stress. In addition to its N-terminal active site, the C-terminal domain including 'YF-motif' of 2-Cys Prx plays a critical role in the structural changes. Therefore, the C-terminal truncated 2-Cys Prxs are not able to regulate their protein structures and highly resistant to $H_2O_2$-dependent hyperoxidation, suggesting that the reaction is guided by the peroxidatic Cys residue. Based on the results, it may be concluded that the peroxidatic Cys of 2-Cys Prx acts as an '$H_2O_2$-sensor' in the cells. The oxidative stress-dependent regulation of 2-Cys Prx provides a means of defense systems in cells to adapt stress conditions by activating intracellular defense signaling pathways. Particularly, 2-Cys Prxs in plants are localized in chloroplasts with a dynamic protein structure. The protein undergoes conformational changes again oxidative stress. Depending on a redox-potential of the chloroplasts, the plant 2-Cys Prx forms super-molecular weight protein structures, which attach to the thylakoid membranes in a reversible manner.

A Study on Avant-Garde Fine Art during the period of Japanese Colonial Rule of Korea, centering on 'Munjang' (a literary magazine) (일제강점기 '전위미술론'의 전통관 연구 - '문장(文章)' 그룹을 중심으로)

  • Park, Ca-Rey
    • The Journal of Art Theory & Practice
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    • no.4
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    • pp.57-76
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    • 2006
  • From the late 1920s to the 1930s, Korea's fine art community focused on traditional viewpoints as their main topic. The traditional viewpoints were discussed mainly by Korean students studying in Japan, especially oil painters. Such discussions on tradition can be divided into two separate halves, namely the pre- and post-Sino-Japanese War (1937) periods. Before the war, the modernists among Korea's fine art community tried to gain a fuller understanding of contemporary Western modern art, namely, expressionism, futurism, surrealism, and so forth, on the basis of Orientalism, and borrow from these schools' in order to create their own works. Furthermore, proponents of Joseon's avant-garde fine arts and artists of the pro-fine art school triggered debate on the traditional viewpoints. After the Sino-Japanese War, these artists continued to embrace Western modern art on the basis of Orientalism. However, since Western modern fine art was regressing into Oriental fine art during this period, Korean artists did not need to research Western modern fine art, but sought to study Joseon's classics and create Joseon's own avant- garde fine art in a movement led by the Munjang group. This research reviews the traditional view espoused by the Munjang group, which represented the avant-garde fine art movement of the post-war period. Advocating Joseon's own current of avant-garde fine art through the Munjang literary magazine, Gil Jin - seop, Kim Yong-jun and others accepted the Japanese fine art community's methodology for the restoration of classicism, but refused Orientalism as an ideology, and attempted to renew their perception of Joseon tradition. The advocation of the restoration of classicism by Gil Jin-seop and Kim Yong-jun appears to be similar to that of the Yasuda Yojuro-style restoration of classicism. However, Gil Jin-seop and Kim Yong-jun did not seek their sources of classicism from the Three-Kingdoms and Unified Silla periods, which Japan had promoted as a symbol of unity among the Joseon people; instead they sought classicism from the Joseon fine art which the Japanese had criticized as a hotbed of decadence. It was the Joseon period that the Munjang group chose as classicism when Japan was upholding Fascism as a contemporary extremism, and when Hangeul (Korean writing system) was banned from schools. The group highly evaluated literature written in the style of women, especially women's writings on the royal court, as represented by Hanjungnok (A Story of Sorrowful Days). In the area of fine art, the group renewed the evaluation of not only literary paintings, but also of the authentic landscape paintings refused by, and the values of the Chusa school criticized as decadent by, the colonial bureaucratic artists, there by making great progress in promoting the traditional viewpoint. Kim Yong-jun embraced a painting philosophy based on the painting techniques of Sasaeng (sketching), because he paid keen attention to the tradition of literary paintings, authentic landscape paintings and genre paintings. The literary painting theory of the 20th century, which was highly developed, could naturally shed both the colonial historical viewpoint which regarded Joseon fine art as heteronomical, and the traditional viewpoint which regarded Joseon fine art as decadent. As such, the Munjang group was able to embrace the Joseon period as the source of classicism amid the prevalent colonial historical viewpoint, presumably as it had accumulated first-hand experience in appreciating curios of paintings and calligraphic works, instead of taking a logical approach. Kim Yong-jun, in his fine art theory, defined artistic forms as the expression of mind, and noted that such an artistic mind could be attained by the appreciation of nature and life. This is because, for the Munjang group, the experience of appreciating nature and life begins with the appreciation of curios of paintings and calligraphic works. Furthermore, for the members of the Munjang group, who were purists who valued artistic style, the concept of individuality presumably was an engine that protected them from falling into the then totalitarian world view represented by the Nishita philosophy. Such a 20th century literary painting theory espoused by the Munjang group concurred with the contemporary traditional viewpoint spearheaded by Oh Se-chang in the 1910s. This theory had a great influence on South and North Korea's fine art theories and circles through the Fine Art College of Seoul National University and Pyongyang Fine Art School in the wake of Korea's liberation. In this sense, the significance of the theory should be re-evaluated.

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The Formation Process of Tribal Landscape through Place Attachment of the Haeju Oh Family at Gohak-ri, Geochang (거창 고학리 해주오씨의 장소애착을 통해 본 종족경관의 형성과정)

  • Lee, Hyun-Woo
    • Journal of the Korean Institute of Landscape Architecture
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    • v.41 no.5
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    • pp.28-37
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    • 2013
  • This research, which sought to conjecture the formation process of tribal landscape while confirming the method and characteristic of place attachment of the Haeju Oh Family, which is rooted within the village and the Yongwon Pavilion and Garden of Gohak-ri, Mari-myeon, Geochang-gun, Gyeongnam, reached the following conclusion based on the interpretation and analysis of cultural and scenic elements such as the names and sculptures nearby the village and Yongwon Pavilion and Garden. This place is where Goohwagong Oh Sue, a Haeju person, settled down. This is also where his descendants were refined while yearning for their ancestors. The Yongwon Pavilion was established in 1964. It can be sufficiently known that this place was managed and maintained as a garden-like place where the spirit of yearning was shared and which was the basis of the life and entertainment of descendants after being the monumental place for Master Oh Guhwa, through stories, documents, nearby facilities, and writings on many rocks. It is clear that the meaning of 'Bang-Hak(訪鶴) and Jung-Hak (停鶴)' which is carved in many places around this area and Gohak-ri, which symbolizes the Hakbong(crane peak), the vein of Wonjak-dong which is one of the Ahneuisamdong(three outstanding scenic places of Ahneui), is a scenic language explaining the ecological settlement and lives of the Haeju Oh Family. When considering the definition of a sense of place as "a 'social device' made by discussions and practice rather than its existing as a substance," the many structures scattered around the village, Yongwon Pavilion Garden, and nearby designations show the monumental place inheritance of tribal group clearly exhibiting the characteristics of a Korean sense of place. Ever since Guhwagon Oh Sue settled down in Guhak-ri, the tribal group of Haeju Oh Family went through a life settlement phase and landscape formation phase by realizing the sense of place. Afterwards, while yearning for ancestors and repeatedly rooting down in the place, territoriality expanded and the place was reproduced. In particular, timber houses and monuments were constructed during the Japanese Colonization Period, and after independence, the Yongwon Pavilion was constructed through place reproduction, and monumental tribal landscape is currently being expressed in various forms to this day. Thus, allowing to reach the conclusion of 'Tribal Landscape of Gohak-ri, Mari-myeong, Geochang-gun,' which we perceive today. The products of territorial expansion formed by the repeating phenomenon of place rootedness and place attachment by tribal groups are in fact the substance of tribal landscape. Through such, it is possible to confirm the true spirit of place attachment and the earnest interest and affection of descendants towards a unique place that is repeatedly constructed and inherited within the group memory.

Evaluation of Cell Death and the Reduction of ERK Phosphorylation in Non-Small Cell Lung Cancer Cells after Exposure to Sodium Butyrate (Sodium butyrate 노출에 의한 비소세포폐암 세포의 세포사멸과 extracellular signal-regulated kinase 인산화의 감소)

  • Park, Ji-Eun;Lee, Seung-Gee;Lim, Hyun-Ju;Kim, Ji-Young;Chung, Jin-Yong;Kim, Yoon-Jae;Lee, Chang-Hun;Lee, Min-Ki;Yoo, Ki-Soo;Yoo, Young-Hyun;Kim, Jong-Min
    • Journal of Life Science
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    • v.19 no.9
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    • pp.1314-1320
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    • 2009
  • Histone deacetylase inhibitor (HDACI) is a new promising candidate as an antineoplastic agent for the treatment of solid and hematologic malignancies. In order to evaluate cell death and to elucidate the related mechanism(s) in NSCLC cells after HDACI, sodium butyrate (SB), a representative HDACI, was used to treat H460 cells for 48 hrs. SB exposure resulted in a significant reduction of cell viability at concentrations below 7.5 mM, and about 50% of cell death occurred at 20 mM. The types of cell death induced by SB were both apoptosis and necrosis, evaluated by Annexin-V staining combined with propidium iodide. SB treatment significantly evoked G2/M cell cycle arrest and subsequently induced cell death with caspase-dependent manner. While ERK protein content was not altered after SB, phosphorylated forms of ERK were markedly reduced. Taken together, SB is significantly able to induce cell death in NSCLC cell line H460, and it is suggested that the reduction of ERK phosphorylation might be closely involved in the cancer cell death mechanism initiated by HDACI.