• 기술사
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• 제35권4호
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• pp.29-33
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• 2002

WATER, the best known and most abundant of all chemical compounds occurring in relatively pure form on the earth"s surface . And life, the material of which organisms are made by water and protoplasm. Especially, between human life and water must be joined by human"s protoplasm, proteins, nucleic acids cells energy exchange and anothers. Therefore. health of mankind is In according to drink enough clean water and to use good water environment.

• 동아시아식생활학회지
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• 제2권1호
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• pp.103-107
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• 1992

The antitumor activity of Omija water extract on sarcoma 180 transplanted intraperitoneal administration in ICR mice was investigated. combined treatment with Omija water extract and Cyclophosphamide augmented antivity against the solid form of Sarcoma 180 in ICR mice.

• 건축역사연구
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• 제7권3호
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• pp.137-149
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• 1998

The purpose of this study is to learn from a lesson of the historical fact, the Team 10's break away from the CIAM, which is selected as the most important event in the whole 20th century architecture by author as a historian. The CIAM, organized in 1928 by leading European architects in order to propose new architecture in the industrial era, expanded to the world, met almost annually with an idea of economic efficiency, new functional order, and industrial production for thirty years. Young architects had conflicted with old established group from 6th congress, and after 10th congress they met independently in 1959; the CIAM was disappeared and the Team 10 was born. Main issue of the break-away was human aspect. The Team 10 started from real man, concept of 'human contact', 'sense of community', and 'belonging' instead of abstract functional order. Although CIAM did not suggest inhumane architecture, their biological criteria with sunlight, air, sufficient site became physical determinism. Critique against the Team 10, unsuccess for making humane architecture leads to underestimation like a generational hegemony struggle. However, architect is not specialist of life but form. Historical reevaluation for Team 10 should be that they are the first group to raise an human issue in architecture. Success or not to solve the problem belongs to another domain. After 1960, modern architecture was attacked from the common people, not clients but 'users'. Academic circle tried to solve the problem with behavioral approach through a clear process, 'design method' and with phenomenological approach on real human experience. However practice became reactionary tendency, to make form a little complex, they became post-modern and deconstruction form. Failure of the Team 10's form proved that a complex form does not necessarily make a good life of people. In the Korean historic situation of colony ruling, confusion of liberation, and the War, we did not know the existence of both CIAM and Team 10. After 1970s' economic development, we have just copied Western form from Modern via Post-Modern to Deconstruction. If we make architecture people mattered, we should start from the basic, learning from the Team's break-away, instead of copying.

• 동의생리병리학회지
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• 제22권1호
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• pp.194-198
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• 2008

The treatment before growing into disease is the highest level of the spirit of oriental preventive public medicine. Specially the treatmentt is very important in the life style disease of the aged society, and it is closely connected the human body-form diagnosis reflecting the character of individual physiology and pathology. The human body-form diagnosis explain systematically the color of face, the form and movement of the body, the smell and the taste, the mentality, many or few of $Yin{\cdot}Yang$, the state of pulse, the Meridian, the state of pathology and the direction of the treatment, and therefore the human body-form diagnostis method has also the practical ity on classifying the type. As the spirit of oriental preventive public medicine is based on the Meridian control method and food cooking control method, it has an important effect on the general management of the disease, the making on the beautiful face and the healthy body, the prolongation of life, the management of the individual-ordered health.

• 한국생태학회:학술대회논문집
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• 한국생태학회 1998년도 춘계공동 학술발표대회
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• pp.97.2-97.2
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• 1998

• 한국환경복원기술학회지
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• 제14권6호
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• pp.57-69
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• 2011

The present paper deals with a research of life form and vegetation of the plants extant in the habitat of endangered Parnassius bremeri in Uiseong, Gyeongsangbuk-do with a view to restore their habitat and create substitute habitats. The research found that there are a total of 130 vascular plants including 47 families, 96 genera, 113 species, 1 subspecies and 16 varieties. In terms of their life form, hemicryptophytes (H) is the majority of dormancy form with 41 species or 31.54%, while $R_5$ is majority of radicoid form with 72 species or 55.38%, gravitational disseminule form ($D_4$) is majority among the disseminule forms with 68 species or 52.31% and erect type (e) is majority of growth form with 57 species or 43.85%. Major constituents of the habitat are Sedum kamtschaticum, Selaginella tamariscina, Orostachys japonica, Arundinella hirta, Cymbopogon tortilis var. goeringii, Themeda triandra var. japonica, Carex humilis, Indigofera kirilowii, Imperata cylindrica var. koenigii, Festuca ovina, Artemisia capillaris, etc., all of species which are in the initial stage of succession and show simultaneously features characteristic of vegetation on the rock. In the habitat 1. Sedum kamtschaticum- Selaginella tamariscina community and Pinus densiflora community are distributed whereas, in the habitat 2. Sedum kamtschaticum-Selaginella tamariscina community, Sedum kamtschaticum-Carex humilis community, Sedum kamtschaticum-Cymbopogon tortilis var. goeringii community and Sedum kamtschaticum-Imperata cylindrica var. koenigii community are growing and in the habitat 3. Sedum kamtschaticum-Selaginella tamariscina community, Selaginella tamariscina community, Sedum kamtschaticum-Indigofera kirilowii community and Quercus acutissima community are seen distributed there, too. Typical of food plants growing in the habitat is Sedum kamtschaticum, found mostly in the rocky area and its surroundings. Absorption plants are those that usually bloom in the season when imagoes emerge. From the research, it becomes evident that the blooming season of Sedum kamtschaticum, obviously a food plant, corresponds exactly to the emergence timing of imagoes. Cirsium japonicum var. ussuriense, Rosa multiflora, Erigeron annuus, Spiraea prunifolia var. simpliciflora are found to belong to these plants.

• 한국실내디자인학회논문집
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• 제22권6호
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• pp.79-87
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• 2013

The purpose of this study clarifies an expression characteristic of the phenomenal space. The architecture is an interface between human and nature. Nature presents herself as phenomena. Thus, the phenomenal space should be approached as the essence of architecture that is to accommodate nature. Phenomenon is related to everyday life and shares flow naturally within it. The phenomenon and everyday life form a relationship through the mediating elements that are time, place, and image. If these mediating elements are developed as spatialized elements, time becomes the converse, place becomes the overlap, and shape becomes the revealing. Also, spatial components that are substituted with these elements are void/solid, form, and materials. The relational characteristics of phenomenal space can be identified through these, and such characteristics are one-ness, continuity, and coincidence of opposites. Phenomenal space is expressed with spatial tones and accepted as spatial atmospheres. For the analysis, 15 works of swiss architects were selected to which spatial elements were applied. And It were composed that analysis by arranging these components as the relational network found that expression characteristics. Trough the analysis, It was found that expression characteristics of phenomenal space of the architecture of Swiss architects were prototypicality, primitiveness, and originality. As a results, It is considered that the role of the space that contains the value of everyday life, the value of the phenomenon is necessary.

• 한국가구학회지
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• 제28권4호
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• pp.278-285
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• 2017

The meaning and context of objects has been changed in various ways depending on the times. Functionality of objects has been developed in various directions according to the point of view of the objects. Objects have been used as mediums to realize art in daily life, and to realize the relational forms. Based on this, it is confirmed that furniture can be an appropriate medium to articulate everyday life and to derive relational form. The 'furniture as a behavior' has the following characteristics. First, it functions to make daily life unfamiliar. By doing something unfamiliar in everyday life, users experience similar experiences as when they entered the surreal world of art museum. In this way, the possibility of everyday arts is acquired. Second, the mental and behavioral functions of furniture are continuously changed by interaction with the user. Behavior does not occur unconsciously, but involves changes in consciousness that the user intentionally does. Therefore, as the user's level of consciousness grows, personal experience changes, and the behavioral function of the household changes. The study of 'furniture as a behavior' is suggested as one approach to design furniture.

• BMB Reports
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• 제38권6호
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• pp.717-724
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• 2005

The nontoxic B subunit of cholera toxin (CTB) can significantly increase the ability of proteins to induce immunological tolerance after oral administration, when it was conjugated to various proteins. Recombinant CTB offers great potential for treatment of autoimmune disease. Here we firstly investigated the feasibility of silkworm baculovirus expression vector system for the cost-effective production of CTB under the control of a strong polyhedrin promoter. Higher expression was achieved via introducing the partial non-coding and coding sequences (ATAAAT and ATGCCGAAT) of polyhedrin to the 5' end of the native CTB gene, with the maximal accumulation being approximately 54.4 mg/L of hemolymph. The silkworm bioreactor produced this protein vaccine as the glycoslated pentameric form, which retained the GM1-ganglioside binding affinity and the native antigenicity of CTB. Further studies revealed that mixing with silkworm-derived CTB increases the tolerogenic potential of insulin. In the nonconjugated form, an insulin : CTB ratio of 100 : 1 was optimal for the prominent reduction in pancreatic islet inflammation. The data presented here demonstrate that the silkworm bioreactor is an ideal production and delivery system for an oral protein vaccine designed to develop immunological tolerance against autoimmune diabetes and CTB functions as an effective mucosal adjuvant for oral tolerance induction.

• Journal of Microbiology and Biotechnology
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• 제15권6호
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• pp.1397-1401
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• 2005

Bone morphogenetic protein-4 (BMP-4) is a signaling homodimeric molecule that acts as a morphogen to influence cell fate in a concentration-dependent manner. The limited supply of a pure preparation of BMP-4, due to very low level of their expression in vivo, makes it difficult not only to study the biological activities of BMPs, but also to use them as a clinical tool. For a large-scale production of BMP-4, human BMP-4 cDNA was expressed in Chinese hamster ovary (CHO) cells by a recently development vector system, which confers position-independent stable expression of the foreign genes. The CHO cell line expressing recombinant human BMP-4 (rhBMP-4) at the level of $7\;{\mu}g/ml$ could be obtained after stepwise selection with methotrexate. This level of expression is about 70 times higher than those previously reported. The partially processed form of BMP-4 as well as mature form could be detected, when the aliquots of culture media were analyzed by Western blot. The glycosylation pattern and biological activity of the rhBMP-4 were determined by glycosidase treatment and the induction rate of alkaline phosphatase in mouse osteoblastic cells.