• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.313-313
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• 2017

Cold stress is one of the most influenced factors to rice yield. In order to identify genes related to cold stress in fertility stage, genome-wide association study (GWAS) was conducted. Cultivated 129 rice germplasm were moved in the growth chamber under the condition of $12^{\circ}C/RH70%$(12h day/12h night when the rice plant was grown in 10 DBH(days before heading). Also, rice plant as control was moved in the green house under condition of $28^{\circ}C/RH70%$(12h day/12h night). After 4 days the plants were moved in a greenhouse. The fertility of rice plant were monitored after the grain were fully grown. The most tolerant rice germplasm to cold stress were Cheongdo-Hwayang-12 and IR38 as 63.1 and 61.8 of fertility and the most recessive rice germplasm were Danyang38 and 8 rice germplasm as 0. As a result of GWAS with re-sequencing data and fertility after cold treatment germplasm using genome association and prediction integrated tool (GAPIT), 99 single-nucleotide polymorphisms (SNPs) were observed by applying a significance threshold of -logP>4.5 determined by QQ plot. With SNPs region, 14 candidate genes responded to cold stress in fertility stage were identified.

• Industrial Engineering and Management Systems
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• 제14권2호
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• pp.183-195
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• 2015

In this paper, we propose a two-stage group acceptance sampling plan for generalized inverted exponential distribution under truncated life test. Median life is considered as a quality parameter. Design parameters are obtained to ensure that true median life is longer than a given specified life at certain level of consumer's risk and producer's risk. We also explore situations under which design parameters based on median lifetime can be used for other percentile points. Tables and specific examples are reported to explain the proposed plans. Finally a real data set is analyzed to implement the plans in practical situations and some suggestions are given.

• Asian Pacific Journal of Cancer Prevention
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• 제16권16호
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• pp.6929-6934
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• 2015

Background: Real life management of hepatocellular carcinoma occasionally deviates from guidelines for recommended therapy. Aims: To evaluate how frequent this deviation happens in our center and assess its impact on outcome. Materials and Methods: The treatment of 770 patients (87% males, mean age 57.8 years) was analyzed and the effect of deviation on outcome over 36 months was examined. Results: Of Barcelona Clinic liver cancer stages 0 and A patients, 65.8% received resection, ablation, liver transplantation or transarterial chemoembolisation for unresectable tumors more than 5 cm in diameter, and 34.2% received treatment recommended for later stages. Of stage B patients, 62.2% received recommended therapy, 34.3% of patients received supportive therapy or sorafenib and 3.5% received upward treatment stage migration. Among stage C patients, 7.6% received sorafenib, and most (79.2%) were given supportive care. Deviation from recommended therapy occurred in 34.2%, 37.7%, and 92.4% in stages 0-A, B and C. Survival of stage 0-A patients who received downwards treatment stage migration was lower than those who received recommended treatment (p <0.001). Upward treatment stage migration in stages B, C and D did not improve survival compared to those who received recommended treatment. Conclusions: Deviation from recommended therapy had a negative impact on survival in Barcelona Clinic liver cancer stage A patients.

• Journal of Hospice and Palliative Care
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• 제7권1호
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• pp.8-16
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• 2004

목적: 본 연구는 자궁경부암 환자의 삶의 질을 파악하고, 질병 진행 단계와 치료 형태에 따른 삶의 질을 분석하는데 있다. 방법: 자료 수집은 3개의 종합병원에서 자궁경부암 환자 67명을 대상으로 하였으며, 자료수집 기간은 3월 15일부터 6월 4일까지 이었다. 연구 도구로는 Ferrell[18]의 삶의 질-암 환자용 도구(Quality of Life-cancer version)를 번역하여, 자궁경부암 환자에게 맞지 않는 4문항을 제외한 총 37문항으로 사용하였다. 자료 분석은 SPSS 통계프로그램을 이용하여, t-test, ANOVA, Scheffe test로 검증하였고 도구의 신뢰도 검증은 Cronbach's Alpha를 산출하였다. 결과: 자궁경부암 환자의 질병 진행 단계에 따른 삶의 질 정도는 유의한 차이가 있었다.(F=5.06, P=.003) 질병 진행 단계에 따른 영역별 삶의 질 정도에서는 신체적 안녕 영역(F=3.97 P=.012), 정신적 안녕 영역(F=3.91, P=.013), 사회적 안녕 영역(F=4.96, P=.004)에는 유의한 차이를 보였으나, 영적 안녕 영역(F=1.36, P=.262)은 유의한 차이를 보이지 않았다. 치료 형태에 따른 삶의 질정도는 유의한 차이를 보이지 않았다.(t=-1.83, P=.073) 치료 형태에 따른 영역별 삶의 질정도에서는 정신적 안녕 영역(t=-2.14, P=.037), 사회적 안녕 영역(t=-2.15, P=.036)에는 유의한 차이를 보였으나, 신체적 안녕 영역(t=-.93, P=.356), 영적 안녕 영역(t=.73, P=.469)에는 유의한 차이가 없었다. 결론: 자궁경부암 환자의 삶의 질은 질병 진행단계와 치료 형태 및 일반적 특성에 따라 차이가 있었다. 그러므로 자궁경부암 환자에게 질병 진행 단계와 치료 형태 및 일반적 특성을 고려한 간호 중재를 적용할 필요가 있다.

• 한국수산과학회지
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• 제46권6호
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• pp.970-972
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• 2013

We examined the relative growth of Microstomus achne during early life stages of laboratory-reared larvae and juveniles. Turning points in the relative growth of preanal length and upper jaw length against total length occurred during the settlement period (11.12-19.91 mm in total length). However, turning points in the relative growth of head length and eye diameter, as compared to total length, occurred during metamorphosis (17.57-22.47 mm in total length). Our results suggest that Microstomus achne concentrates its energy on the feeding apparatus (jaw) and digestive organs (intestine) rather than sensory or neural organs (eye, head) during early larval stage growth.

• 대한간호학회지
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• 제30권4호
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• pp.956-966
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• 2000

The purpose of this study was to examine the comparative between depression and stress related to life events among women in the menopausal stage. Menopausal stages were divided into two groups: Pre and post-menopausal stages. The degree of depression and stress related to life events between pre and post menopausal women were compared to each other. Women, aged between 41 and 59 years, answered self-reported questionnaires which included Zung's depression scale and life events scale modified by Lee (1984). Findings were as follows; 1) The mean score of premenopausal women who experienced depression was 39.66, and for post-menopausal women the score was 41.45. There was no significant differences in depression levels between pre and post menopausal group.s (t=-1.55, p=.122). 2) Menopausal women experienced low levels of stress related to life events. There were no significant differences between pre and post menopausal groups(t=.527, p>.05). Both pre and post menopausal groups were highly concerned about education issues of their children and disharmony between couples. 3) There was a significant relationship between depression and stress related to life events among post-menopausal groups (r=.22, p<.01). Based on the findings of this study, the menopausal depression was associated with stress related to life events, especially among post-menopausal women. Feelings of lost fertility and feminine attributies result in menopausal depression, which is significantly correlated with women's negative perception of their life events. Therefore, nursing intervention needs to develop to help reduce the levels of depression and overcome their negative perception of the menopausal experience. Nurses should develop nursing strategies to help menopausal women to have positive perceptions and enhance quality of life by assisting their adaptability to physiological and psychological changes related to menopause.

• 농업생명과학연구
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• 제50권4호
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• pp.147-155
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• 2016

본 연구에서는 육상양식장에서 배출되는 부산물의 자원화 방안으로 뱀장어 양식장에서 배출되는 고형오물에 미강, 탈지대두박과 같은 식품 부산물을 첨가하여 유산균, 황국균, 고초균을 단계적으로 접종하여 발효시킨 발효사료의 성분 변화를 측정하였다. 발효사료의 제조 단계별 수분함량은 유산균을 이용한 1단 발효물 14.6%, 황국균과 고초균을 이용한 2단, 3단 발효물은 각각 33.0%와 34.0% 였다. pH는 1단 발효물에서는 유산균에 의한 젖산의 분비로 인해 5.38로 나타났으며 2단, 3단 발효물은 각 5.66과 7.26으로 측정되어 pH가 상승하는 것으로 나타났다. 피트산의 함량은 1단 발효물은 0.126g/100g, 2단 발효물은 0.004g/100g, 3단 발효물은 0.093g/100g으로 나타나는 것을 확인 할 수 있었다. 질소 함량을 측정한 결과 아미노태질소 함량은 2단 발효물이 1226.37mg%로 높았고, 3단 발효물에서 710.18mg%로 다소 감소하였으며, 암모니아태질소 함량은 1단 발효물 0.988mg/kg에서 3단 발효물 1.502mg/kg로 증가되었다. 총질소 함량은 1단 발효물 2.78%와 2단 발효물 4.08% 그리고 3단 발효물 4.85%로 증가되었다. 3가지 미생물로 연속적인 발효가 진행될수록 피트산은 감소하고 단백질 분해율이 높아지는 경향이 나타났고 3단 발효에 의해 저분자 질소성분 함량이 증가한 것으로 미루어 소화 흡수성이 높은 사료화가 진행됨을 추측할 수 있다.

• 가정과삶의질연구
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• 제8권1호
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• pp.83-100
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• 1990

The purposes of the study are to understand of rural family life cycle(FLC) and to get a FLC model for the twentieth in rural area. Data for the study were collected from 603 farm households in rural area. The major findings are as follows; 1) The age of first marriage was 21.5 years old(urban : 22.4), the first bearing 23.2(24.2), the last bearing 31.7(32.6), the first child marriage 47.2(46.5), and the last child marriage 59.7(52.7). The number of child and interval were 3.9 persons and 2.9 years respectively. From the survey results, the rural family life cycle was established. Establishment stage(from the marriage to the 1st child birth) : 21-23 yrs. Extension stage(from the 1st child birth to the last child birth) : 23-32 yrs. Complete extension stage(from the last child birth to the 1st child's marriage) : 32-47 yrs. Shrinking stage(from the 1st child's marriage to the last child's marriage) : 47-60 yrs. Complete shrinking stage(from the last child's marri ge to the death of husband) : 60-63 yrs. Dissolution stage(from the death of husband to the death of wife) : 53-75 yrs. 2) In general, the older the age, the younger the first marriage age, the greater the number of child, and the longer the interval of child bearing. The last child's marriage was too last to have the period of recovery stage. In terms of FLC by marital chorts, the later the year of marriage, the older the age of the first marriage and first baby bearing, the smaller the number of child, and the faster the launching stage. The higher the educational level, the older age of the first marriage and the first baby bering, the smaller the number of child, and the shorter the interval of child bearing. 3) Two types of rural FLC model for the twentieth were formulated. Type A was formulated based on the survey results and type B was formulated based on 『'88 population dynamics survey』 of Economic Planning Board(EPB). 「TYPE A」*Establishment stage(from the marriag to the 1st child birth) : 22.5-23.5 yrs. one child : the 1st child's marriage(49.5yrs), the death of husband(64.2yrs), the death of wife(71.7yrs) two children : the last child's birth(25.7yrs), the last child's marriage(51.7 yrs) three children : the last child's birth(27.9yrs) the last child's marriage(53.9yrs) 「TYPE B」*Establishment stage(from the marriage to the 1st child birth) : 25.3-26.3 yrs. one child : the lst child's marriage(52.3yrs), the death of husband(67.0yrs), the death of wife(74.5yrs) two children : the last child's birth(27.8yrs), the last child's marriage(53.8 yrs.) three children : the last child's birth(29.3yrs), the last child's marriage(55.3yrs).

• 한국조경학회지
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• 제43권6호
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• pp.25-40
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• 2015

우리나라 관광지는 관광진흥법에 따라 지정 관리되고 있으며, 1969년 태종대 관광지가 지정된 이후 현재까지 총 230개소의 관광지가 지정, 조성, 운영되고 있다. 최초 관광지가 지정된 이후 46년이라는 시간이 흘렀으며, 이는 Butler가 주장한 관광지 수명주기 이론에 따라 영고성쇠와 같은 수명주기의 흐름을 보이고 있을 것으로 추정된다. 이에, 본 연구에서는 Butler의 관광지 수명주기 이론을 적용하여 국내 관광지의 수명주기 단계를 분석하고, 향후 관광지가 변화 발전되어야 할 방향성을 제시하는데 기초자료로 활용하고자 연구를 진행하였다. 연구방법은 대상 관광지별 연간방문객수 데이터를 기반으로 변화추이곡선을 도출하였으며, 방문객수 변화율을 기준으로 관광지 수명주기 단계를 구분하였다. 분석 결과, 국내 관광지의 3분의 1 이상이 정체 쇠퇴 단계에 도달하고 있는 것으로 분석되었으며, 특히 온천, 해안/해수욕장 자원유형 관광지가 정체 쇠퇴단계 비율이 높은 것으로 분석되었다. 정체 쇠퇴단계에 도달해 있는 관광지는 쇠퇴의 원인 분석과 해결방안 모색, 새로운 혁신요소 도입의 필요성이 대두되었다. 본 연구의 결과가 국내 관광지의 수명주기 단계를 결정하는 절대적인 기준이 되기에는 부족한 점이 있으나, 우리나라 관광지의 수명주기 단계를 현상학적으로 파악하기에는 적절한 것으로 사료되며, 본 연구를 바탕으로 정체 쇠퇴단계에 도달한 관광지들의 원인을 규명하고, 이를 토대로 새로운 혁신 도입을 통해 관광지의 재활성화 방안 마련의 기초 연구로 활용될 수 있을 것으로 생각된다.

• Journal of Ecology and Environment
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• 제36권4호
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• pp.223-233
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• 2013

Acid deposition is one of the most serious environmental problems in ecosystems. The present study surveyed the effects of simulated acid rain on leaf litter mass loss and microbial community in the decomposing leaf litter of Sorbus anifolia in a microcosm at $23^{\circ}C$ and 40% humidity. Microbial biomass was measured by substrate-induced respiration (SIR) and phospholipid fatty acids (PLFAs), and the microbial community structures were determined by composition of PLFAs at each interval of decomposition in litter sample and at each pH treatment. The microbial biomass showed peaks at mid-stage of decomposition, decreasing at the late stage. The leaf litter mass loss of S. anifolia decreased with decreasing pH during early and mid-decomposition stages; however the mass loss becomes similar between pH treatments at late-decomposition stage. The acidification remarkably lowers the microbial biomass of bacteria and fungi; however, microbial diversity was unchanged between pH treatments at each stage of litter decomposition. With changes of decomposition stage and pH treatment there were considerable differences in replacement and compensation of microbial species. Fungi/bacteria ratio was considerably changed by pH treatment. The PLFA profile showed significantly larger fungi/bacteria ratio at pH 5 than pH 3 at the early stage of decomposition, and the difference becomes smaller at the later decomposition stage. At low pH, pH 3 and pH 4, the fungi/bacteria ratios were stable according to the litter decomposition stages. Simulated acid rain caused decreases of 10Me17:0, 16:1${\omega}$7c, 18:1${\omega}$7, 15:0, but increase of 24:0. In addition, litter mass loss showed significant positive correlation with microbial biomass measured by SIR and PLFA on the decomposing leaf litter.