• Title/Summary/Keyword: Life safety index

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Effects of Manual Therapy on Obstructive Sleep Apnea: Study Protocol for a Systematic Review (폐쇄성 수면무호흡증에 대한 수기요법의 효과: 체계적 문헌고찰을 위한 프로토콜)

  • Jiwon Park;Kwan-Il Kim
    • Journal of Korean Medicine Rehabilitation
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    • v.34 no.3
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    • pp.65-74
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    • 2024
  • Objectives This study aims to establish a protocol for a systematic review to evaluate the effectiveness and safety of manual therapy (MT) for obstructive sleep apnea (OSA). Methods We will conduct a search for relevant randomized controlled trials using seven databases, including MEDLINE/PubMed, Embase, and the Cochrane Central Register of Controlled Trials. The study includes patients with OSA treated with MT. Comparators include all other treatments excluding MT. The primary outcome is the apnea-hypopnea index; secondary outcomes include mean peripheral oxygen saturation, snoring index, quality of sleep, quality of life, peak nasal inspiratory flow, and adverse events. Results Two independent researchers will select studies based on inclusion criteria and extract necessary data. Risk of bias (RoB) will be assessed using the Cochrane RoB 2.0 tool. Meta-analysis will be conducted if there are two or more studies with the same outcome measure; otherwise, a qualitative analysis will be performed. Subgroup analysis will be conducted based on the type of MT, and evidence certainty will be evaluated using the Grading of Recommendations Assessment, Development, and Evaluation approach. Conclusions This study will evaluate the effect of MT on OSA. By systematically reviewing various MTs, it aims to refine application methods in clinical practice and provide a foundation for future research.

Study on Displacement Behavior of Abandoned Mine Goaf Cave According to Filling Factor (충전율에 따른 폐광산 채굴적 공동의 변위거동에 관한 연구)

  • Kim, Dong-Rak;Seo, In-Shik
    • Journal of the Korean Society of Industry Convergence
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    • v.14 no.4
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    • pp.151-156
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    • 2011
  • The domestic mine development community the countermeasure establishment is insufficient about ground sinkage, not only the mine which is a in line is partial from the mine of the most which has become the rest mine and abandoned mine or the index sinkage occurs. The ground sinkage which occurs from the abandoned mine area most after operation is stopped, a long time passes and accurately predicts an occurrence location and a time with the residual sinkage which occurs, is difficult. Underground goaf of the abandoned mine and the closed shaft When considering the potentiality which causes the instability of ground, is a possibility of reaching a damage in the ground infrastructure or life. The underground shaft which is formed specially with mine development and goaf operates with the obstacle factor in the development project of the mine area, the ground sinkage which is caused by with sinkage, operates with the large safety accident occurrence factor where the important infrastructure of the railroad, road, residential area etc. is damaged. Therefore, In this paper, the goaf cave of the abandoned mine area, for the displacement behavior according to the filling factor of the material is to analyze the numerical analysis.

Application of ELISA for the Detection of Sulfamethazine Residue in Live Cattle

  • Lee, H.J.;Lee, M.H.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.3
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    • pp.378-381
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    • 2001
  • Sulfamethazine has been widely used in swine for prevention or treatment of infections. Recently, the safety of the drug to consumers has been questioned because of carcinogenic effects. To prevent unwanted drug residues entering the human food chain, both government authorities and industries have established extensive control measures. The demands for reliable, simple, sensitive, rapid and low-cost methods for residue analysis of foods are increasing nowadays. In this study, we established a rapid prediction test for the detection of cattle with violative tissue residues of sulfamethazine. The recommended therapeutic dose of sulfamethazine (withdrawal time, 15 days) was administered to each of 10 cattle. Blood was sampled before drug administration and during the withdrawal period. The concentration of sulfamethazine in plasma, determined by a semi-quantitative ELISA, was compared to that of an internal standard (10 ppb). The absorbance ratio of internal standard to sample (B/Bs) was employed as an index to determine whether drug residues in cattle tissues were negative or positive. That is, a B/Bs ratio less than 1 was considered residue positive and if larger than 1 was considered negative. All 10 plasma samples from non-treated cattle showed negative to sulfamethazine. Sulfamethazine was detected in plasmas of treated cattle until Day 7 of withdrawal period. The present study showed that the semi-quantitative ELISA could be easily adapted in predicting residues of sulfamethazine in live cattle.

A Study on the Shortening Effect of Train Running Time as Railway curve sections improvement (철도곡선부 개량에 따른 열차운행시간 단축효과에 관한 연구)

  • 조규전;이남수;정의환
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.14 no.2
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    • pp.229-239
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    • 1996
  • for shortening of running time on existing line, speed up railways feel strongly the necessity of it, for fully realizing a role of transportation system, for human life style is high. and increasing of time value. Especially curved lines zone have crucial effects on the speed of train, in case the shortening of running time, it is thought, speed up in curved lines zone, considering a character of route alignment in korea, we obtain saving time using lateral force index for safety running of train and comfortable ride of passengers. The results of this study show that all curved zone improvements for the shortening of the train running time more efficiently than extension of transition curve.

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A Study on the Condition of LED Lights Flicker (국내 LED 조명등에서 플리커 현상에 관한 연구)

  • Heo, Min;Ko, Jae-jun;Kim, Chung-hyeok
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.29 no.11
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    • pp.729-735
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    • 2016
  • It is highly important issue to use an energy efficiently for sustainable prosperity of mankind. From this point of view, using LED lighting can be a good alternative because it has a lot of advantages such as high efficiency, long life time and eco-friendly manufacturing process. That is the reason why using LED lighting has been encouraged worldwide. However, in situations that LED lighting is replacing traditional lighting quickly, the problem of the flicker of LED lighting has emerged as an important issue. Therefore, in foreign countries like US or Japan in order to ensure the reliability of LED lighting, study for flickering effects of the human body and test methods are have been actively conducted. But related research in domestic situation is an insufficient condition. In this study, a flicker characteristic was measured conventional lamps such as incandescent lamps or fluorescent lamp and 81 items of LED lightings which are distributed in domestic markets.

Analysis of Flood Resilience of the Stormwater Management Using SWMM Model (SWMM 모델을 이용한 우수 관리 홍수 탄력성 분석)

  • Hwang, Soonho;Kim, Jaekyoung;Kang, Junsuk
    • Proceedings of the Korea Water Resources Association Conference
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    • 2021.06a
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    • pp.126-126
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    • 2021
  • Stormwater reduction plays an important role in the safety and resilience to flooding in urban areas. Due to rapid climate change, the world is experiencing abnormal climate phenomena, and sudden floods and concentrated torrential rains are frequently occurring in urban basins and the amount of outflow due to stormwater increases. In addition, the damage caused by urban flooding and inundation due to extreme rainfall exceeding the events that occurred in the past increases. To solve this problem, water supply, drainage, and water supply for sustainable urban development, the water management paradigm is shifting from sewage maintenance to water circulation and water-sensitive cities. So, in this study, The purpose of this study is to examine measures to increase the resilience of urban ecosystem systems for urban excellence reduction by analyzing the effects of green infra structures and LID techniques and evaluating changes in resilience. In this study, for simulating and analysis of runoff for various stormwater patterns and LID applications, Storm Water Management Model (SWMM) was used.

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A Prospective, Multi-Center, Double-Blind, Randomized Study to Evaluate the Efficacy and Safety of the Synthetic Bone Graft Material DBM Gel with rhBMP-2 versus DBM Gel Used during the TLIF Procedure in Patients with Lumbar Disc Disease

  • Hyun, Seung-Jae;Yoon, Seung Hwan;Kim, Joo Han;Oh, Jae Keun;Lee, Chang-Hyun;Shin, Jun Jae;Kang, Jiin;Ha, Yoon
    • Journal of Korean Neurosurgical Society
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    • v.64 no.4
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    • pp.562-574
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    • 2021
  • Objective : This study is to evaluate the efficacy and safety of demineralized bone matrix (DBM) gel versus DBM gel with recombinant human bone morphogenetic protein-2 (rhBMP-2) used in transforaminal lumbar interbody fusion (TLIF). Methods : This study was designed as a prospective, multi-center, double-blind method, randomized study. All randomized subjects underwent TLIF with DBM gel with rhBMP-2 group (40 patients) as an experimental group or DBM gel group (36 patients) as a control group. Post-operative observations were performed at 12, 24, and 48 weeks. The spinal fusion rate on computed tomography scans and X-rays films, Visual analog scale pain scores, Oswestry disability index and SF-36 quality of life (QOL) scores were used for the efficacy evaluation. The incidence rate of adverse device effects (ADEs) and serious adverse device effects (SADEs) were used for safety evaluation. Results : The spinal fusion rate at 12 weeks for the DBM gel with rhBMP-2 group was higher with 73.68% compared to 58.82% for the DBM gel group. The 24 and 48 weeks were 72.22% and 82.86% for the DBM gel with rhBMP-2 group and 78.79% and 78.13%, respectively, for the DBM gel group. However, there were no significant differences between two groups in the spinal fusion rate at 12, 24, and 48 weeks post-treatment (p=0.1817, p=0.5272, p=0.6247). There was no significant difference between the two groups in the incidence rate of ADEs (p=0.3836). For ADEs in the experimental group, 'Pyrexia' (5.00%) was the most common ADE, followed by 'Hypesthesia', 'Paresthesia', 'Transient peripheral paralysis', 'Spondylitis' and 'Insomnia' (2.50%, respectively). ADEs reported in control group included 'Pyrexia', 'Chest discomfort', 'Pain', 'Osteoarthritis', 'Nephropathy toxic', 'Neurogenic bladder', 'Liver function analyses' and 'Urticaria' (2.86%, respectively). There was no significant difference between the two groups in the incidence rate of SADEs (p=0.6594). For SADE in the experimental group, ''Pyrexia' and 'Spondylitis' were 2.50%. SADE reported in the control group included 'Chest discomfort', 'Osteoarthritis' and 'Neurogenic bladder'. All SADEs described above were resolved after medical treatment. Conclusion : This study demonstrated that the spinal fusion rates of DBM gel group and DBM gel with rhBMP-2 group were not significantly different. But, this study provides knowledge regarding the earlier postoperative effect of rhBMP-2 containing DBM gel and also supports the idea that the longer term follow-up results are essential to confirm the safety and effectiveness.

Collision Risk Assessment by using Hierarchical Clustering Method and Real-time Data (계층 클러스터링과 실시간 데이터를 이용한 충돌위험평가)

  • Vu, Dang-Thai;Jeong, Jae-Yong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.27 no.4
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    • pp.483-491
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    • 2021
  • The identification of regional collision risks in water areas is significant for the safety of navigation. This paper introduces a new method of collision risk assessment that incorporates a clustering method based on the distance factor - hierarchical clustering - and uses real-time data in case of several surrounding vessels, group methodology and preliminary assessment to classify vessels and evaluate the basis of collision risk evaluation (called HCAAP processing). The vessels are clustered using the hierarchical program to obtain clusters of encounter vessels and are combined with the preliminary assessment to filter relatively safe vessels. Subsequently, the distance at the closest point of approach (DCPA) and time to the closest point of approach (TCPA) between encounter vessels within each cluster are calculated to obtain the relation and comparison with the collision risk index (CRI). The mathematical relationship of CRI for each cluster of encounter vessels with DCPA and TCPA is constructed using a negative exponential function. Operators can easily evaluate the safety of all vessels navigating in the defined area using the calculated CRI. Therefore, this framework can improve the safety and security of vessel traffic transportation and reduce the loss of life and property. To illustrate the effectiveness of the framework proposed, an experimental case study was conducted within the coastal waters of Mokpo, Korea. The results demonstrated that the framework was effective and efficient in detecting and ranking collision risk indexes between encounter vessels within each cluster, which allowed an automatic risk prioritization of encounter vessels for further investigation by operators.

Development of Usability Evaluation Criteria for Senior-Friendly Autonomous Transportation Robot

  • Kim, Seon Chil;Kim, Sun Jung;Choi, Kyongon
    • Journal of the Ergonomics Society of Korea
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    • v.33 no.5
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    • pp.407-422
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    • 2014
  • Objective: The purpose of the study is to develop quantitative usability evaluation criteria for senior-friendly autonomous transportation robot. Background: The Republic of Korea has become the most rapidly aging society, and is anticipated to enter the post-aged society in 2026. To raise the quality of life of a senior with limited mobility and to reduce the burden of caregivers, many high-tech assistive products with information technologies are developed nowadays. The senior-friendly autonomous transportation robot is one person robot vehicle to move a senior to the destination for hospitals, nursing homes or silver town complex. With built-in navigation system and environmental monitoring censors, it automatically seeks the path to the destination and avoids collision to obstacles and pedestrians on the way. Due to the early stage of the product, few usability studies in this field have been done, mostly on general service robots to assist seniors, power wheelchairs and delivery robots. ISO and KS standards for the service robots are focused on safety. Method: Based on the reference usability index, the early draft of the usability evaluation questionnaires was developed. After small group tests and interviews, the experts modified the initial draft to the Usability Evaluation Criteria for Senior-Friendly Autonomous Transportation Robot (UEC-SFATR). Result: UEC-SFATR consisted of 4 subscales - Safety, Controllability, Efficiency and Satisfaction. All of the 4 subscales of UEC-SFATR were passed the reliability criteria by 4 groups of seniors, divided by gender and familiarity of smart-devices. Conclusion: UEC-SFATR covers wider area of user experiences of the SFATR and is a good measurement tool to help both the users and developers of the robot. Application: This study provides guide to the future product development and product competitiveness evaluation by quantifying user experiences for the SFATR.

Recent Evolution of Surgical Treatment for Gastric Cancer in Korea

  • An, Ji-Yeong;Cheong, Jae-Ho;Hyung, Woo-Jin;Noh, Sung-Hoon
    • Journal of Gastric Cancer
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    • v.11 no.1
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    • pp.1-6
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    • 2011
  • Gastric cancer is the most common malignancy and the incidence is steadily increasing in Korea. The principal treatment modality for gastric cancer is surgical extirpation of tumor along with draining lymph nodes. Gastrectomy with D2 lymph node dissection has been well established as a standard of surgery and improved the survival of gastric cancer patients. Recently, technological advances are drastically reshaping the landscape of surgical treatment of gastric cancer. One of the most notable trends is that minimal access surgery becomes dominating the treatment of early stage diseases. For advanced diseases, the standard access surgery is considered a reference treatment. Although there is a pilot study underway to evaluate the feasibility of the application of minimal access surgery to advanced gastric cancer (AGC), the evidence for oncological safety is not yet provided sufficiently. Based on the recent randomized controlled trials, the extent of surgery for AGC has re-defined as para-aortic lymph node dissection dose not add any survival benefit while increasing surgery-related morbidities. In addition, it is now accepted as a standard operation omitting unnecessary procedures such as splenectomy and/or distal pancreatectomy for prophylactic lymph node dissection. Conceptual and technical innovation has contributed to decreasing morbidity and mortality without impairing oncological safety. All these recent advances in the field of gastric cancer surgery would be concluded in maximizing therapeutic index for gastric cancer while improving quality of life.