Journal of Korean Medicine Rehabilitation (한방재활의학과학회지)

The society of Korean Medicine Rehabilitation (한방재활의학과학회)
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Effects of Manual Therapy on Obstructive Sleep Apnea: Study Protocol for a Systematic Review

폐쇄성 수면무호흡증에 대한 수기요법의 효과: 체계적 문헌고찰을 위한 프로토콜

  • Jiwon Park (Department of Clinical Korean Medicine, College of Korean Medicine, Graduate School, Kyung Hee University) ;
  • Kwan-Il Kim (Department of Clinical Korean Medicine, College of Korean Medicine, Graduate School, Kyung Hee University)
  • 박지원 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 김관일 (경희대학교 대학원 임상한의학과 폐계내과학교실)
  • Received : 2024.06.21
  • Accepted : 2024.06.22
  • Published : 2024.07.31
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Abstract

Objectives This study aims to establish a protocol for a systematic review to evaluate the effectiveness and safety of manual therapy (MT) for obstructive sleep apnea (OSA). Methods We will conduct a search for relevant randomized controlled trials using seven databases, including MEDLINE/PubMed, Embase, and the Cochrane Central Register of Controlled Trials. The study includes patients with OSA treated with MT. Comparators include all other treatments excluding MT. The primary outcome is the apnea-hypopnea index; secondary outcomes include mean peripheral oxygen saturation, snoring index, quality of sleep, quality of life, peak nasal inspiratory flow, and adverse events. Results Two independent researchers will select studies based on inclusion criteria and extract necessary data. Risk of bias (RoB) will be assessed using the Cochrane RoB 2.0 tool. Meta-analysis will be conducted if there are two or more studies with the same outcome measure; otherwise, a qualitative analysis will be performed. Subgroup analysis will be conducted based on the type of MT, and evidence certainty will be evaluated using the Grading of Recommendations Assessment, Development, and Evaluation approach. Conclusions This study will evaluate the effect of MT on OSA. By systematically reviewing various MTs, it aims to refine application methods in clinical practice and provide a foundation for future research.

Keywords

Acknowledgement

This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: RS-2023-KH139413).

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