• Computational Structural Engineering : An International Journal
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• 제2권1호
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• pp.25-32
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• 2002

Natural draught cooling towers often develop visible crack structures as consequences of progressive damage processes over their life-time. The aim of this paper is a numerical demonstration of the progressive damage process of cooling towers, representatively for the reinforced concrete structures, in order to improve the durability and extend the life-time of structures subjected to such damage processes. For the analyses, the applied material model for reinforced concrete will be briefly introduced. An existing natural draught cooling tower with a pronounced crack structure, in which this crack structure indicates the typical damage pattern of large cooling towers will be numerically simulated. The change of dynamical behavior of the structure with regard to natural frequencies, reflecting the global damage process due to the degrading stiffness of the structure in dependence of the load type and intensity, will be presented and discussed.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 춘계학술대회논문집A
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• pp.7-12
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• 2000

The automatic turbine startup system provides turbine control based on thermal stress. During the startup, control system monitors and evaluates main components of turbine using damage mechanism and life assessment. In case of valve chest, the temperature of inner/outer wall is measured by thermo-couples and the safety of these values are evaluated by using allowable ${\Delta}T$ limit curve during the startup. Because allowable ${\Delta}T$ limit curve includes life assessment, it is possible to apply this curve to turbine control system. In this paper, low cycle fatigue damage and combined rupture and low cycle fatigue damage criterion proposed for yielding the allowable ${\Delta}T$ limit curve of CV(control valve) chest. To calculate low cycle fatigue damage, the stress analysis of valve chest has peformed using FEM. Automatic turbine startup to assure service life of CV was achieved using allowable ${\Delta}T$ limit curve.

• 대한기계학회논문집A
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• 제26권1호
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• pp.1-6
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• 2002

The automatic turbine startup system provides turbine control based on thermal stress. During the startup, control system monitors and evaluates main components of turbine using damage mechanism and life assessment. In case of valve chest, the temperature of inner/outer wall is measured by thermo-couples and the safety of these values are evaluated by using allowable △T limit currie during the startup. Because allowable ΔT limit curve includes life assessment, it is possible to apply this curve to turbine control system. In this paper, low cycle fatigue damage, combined rupture and low cycle fatigue damage criterion were proposed for yielding the allowable ΔTf limit curve of CV(control valve) chest. To calculate low cycle fatigue damage, the stress analysis of valve chest has been performed using FEM. Automatic turbine startup to assure service life of CV was achieved using allowable ΔT limit curve.

• Journal of Microbiology and Biotechnology
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• 제14권4호
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• pp.852-858
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• 2004

The morbidity and mortality of colon cancer are increasing, because of the westernization of food habit. Probiotics such as lactic acid bacteria (LAB) have been known to play an important role in retarding colon carcinogenesis by possibly influencing metabolic, immunologic, and protective functions in the colon. In this study, we evaluated the effect of B. polyfermenticus SCD on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) induced DNA damage in CHO-K, cells and human lymphocytes, and on proliferation of human colon cancer cell. Using the Comet assay to detect DNA damage, we found that B. polyfermenticus SCD protected cells from the DNA damage induced by MNNG in $CHO-K_1$ cells and in human lymphocytes. B. polyfermenticus SCD was also found to inhibit the growth of colon cancer cells in a dose-dependent manner, detected by the MTT assay. These results indicate that B. polyfermenticus SCD has the potential to inhibit not only DNA damage induced by a carcinogen, but also the proliferation of colon cancer cells.

• BMB Reports
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• 제42권8호
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• pp.500-505
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• 2009

Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA of rat hepatocytes damaged by oxidative stress. In addition, a reaction mixture of PLE and RGE showed synergistic inhibitory effect against DNA damage. These results suggest that PLE and RGE have a cellular defensive effect against DNA damage induced by ROS.

• Structural Engineering and Mechanics
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• 제62권2호
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• pp.225-236
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• 2017

The purpose of this work is to predict ductile fracture of structural steel under extremely low cyclic loading experienced in earthquake. A cumulative damage model is proposed on the basis of an existing damage model originally aiming to predict fracture under monotonic loading. The cumulative damage model assumes that damage does not grow when stress triaxiality is below a threshold and fracture occurs when accumulated damage reach unit. The model was implemented in ABAQUS software. The cumulative damage model parameters for steel base metal, weld metal and heat affected zone were calibrated, respectively, through testing and finite element analyses of notched coupon specimens. The damage evolution law in the notched coupon specimens under different loads was compared. Finally, in order to examine the engineering applicability of the proposed model, the fracture performance of beam-column welded joints reported by previous researches was analyzed based on the cumulative damage model. The analysis results show that the cumulative damage model is able to successfully predict the cracking location, fracture process, the crack initiation life, and the total fatigue life of the joints.

• Journal of Biosystems Engineering
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• 제34권5호
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• pp.325-330
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• 2009

This study was performed to develop accelerated life test methods for agricultural tractor transmission receiving variable load. To acquire parameters for calculation of accelerated life test, endurance tests were performed under different torque conditions. Test results showed that the shape factor of Weibull distribution was 1.5 and fatigue damage exponent was 5.4. The calculated test time was 5,877 hours under the conditions of average life (MTBF) 3,000 hours and 90% reliability for one test sample. According to the linear cumulative damage rule, test time could be reduced using increased test load. Test time could be reduced by 252 hours when 1.2 times of the rated load compared with 0.67 times of the rated equivalent load calculated by load spectrum of the agricultural tractor. Calculated acceleration coefficient was 23.3.

• 한국정밀공학회지
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• 제19권8호
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• pp.71-76
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• 2002

In this study low cycle fatigue (LCF) behavior of 12Cr steel at high temperature are described. Secondly, comparisons between predicted lives and experimental lives are made for the several sample life prediction models. Two minute hold period in either tension or compression reduce the number of cycles to failure by about a factor of two. Twenty minute hold periods in compression lead to shorter lives than 2 minute hold periods in compression. Experiments showed that life predictions from classical phenomenological models have limitations. More LCF experiments should be pursued to gain understanding of the physical damage mechanisms and to allow the development of physically-based models which can enhance the accuracy of the predictions of components. From a design point-of-view, life prediction has been judged acceptable for these particular loading conditions but extrapolations to thermo-mechanical fatigue loading, for example, require more sophisticated models including physical damage mechanisms.

• Journal of Microbiology and Biotechnology
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• 제32권7호
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• pp.927-937
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• 2022

To confirm the therapeutic effect of the water extract from Ecklonia cava (WEE) against PM_2.5 induced systemic health damage, we evaluated gut health with a focus on the microbiota and metabolites. Systemic damage in mice was induced through PM_2.5 exposure for 12 weeks in a whole-body chamber. After exposure for 12 weeks, body weight and food intake decreased, and WEE at 200 mg/kg body weight (mpk) alleviated these metabolic efficiency changes. In addition, PM_2.5 induced changes in the length of the colon and fecal water content. The administration of the WEE at 200 mpk oral dose effectively reduced changes in the colon caused by PM_2.5 exposure. We also attempted to confirm whether the effect of the WEE is mediated via regulation of the microbiota-gut-brain axis in mice with PM_2.5 induced systemic damage. We examined changes in the fecal microbiota and gut metabolites such as short-chain fatty acids (SCFAs) and kynurenine metabolites. In the PM_2.5 exposed group, a decrease in the abundance of Lactobacillus (Family: Lactobacillaceae) and an increase in the abundance of Alistipes (Family: Rikenellaceae) were observed, and the administration of the WEE showed a beneficial effect on the gut microbiota. In addition, the WEE effectively increased the levels of SCFAs (acetate, propionate, and butyrate). Furthermore, kynurenic acid (KYNA), which is a critical neuroprotective metabolite in the gut-brain axis, was increased by the administration of the WEE. Our findings suggest that the WEE could be used as a potential therapeutic against PM_2.5 induced health damage by regulating gut function.

• Steel and Composite Structures
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• 제51권1호
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• pp.53-61
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• 2024

Aluminum foams sandwich panel (AFSP) has been used in engineering field, where cyclic loading is used in most of the applications. In this paper, the fatigue life of AFSP prepared by the bonding method was investigated through a three-point bending test. The mathematical statistics method was used to analyze the influence of different plate thicknesses and core densities on the bending fatigue life. The macroscopic fatigue failure modes and damage mechanisms were observed by scanning electron microscopy (SEM). The results indicate that panel thickness and core layer density have a significant influence on the bending fatigue life of AFSP and their dispersion. The damage mechanism of fatigue failure to cells in aluminum foam is that the initial fatigue crack begins the cell wall, the thinnest position of the cell wall or the intersection of the cell wall and the cell ridge, where stress concentrations are more likely to occur. The fatigue failure of aluminum foam core usually starts from the semi-closed unit of the lower layer, and the fatigue crack propagates layer by layer along the direction of the maximum shear stress. The results can provide a reference for the practical engineering design and application of AFSP.