• Title/Summary/Keyword: Life curve

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Blockchain-Based Smart Home System for Access Latency and Security (지연시간 및 보안을 위한 블록체인 기반 스마트홈 시스템 설계)

  • Chang-Yu Ao;Kang-Chul Kim
    • The Journal of the Korea institute of electronic communication sciences
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    • v.18 no.1
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    • pp.157-164
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    • 2023
  • In modern society, smart home has become a part of people's daily life. But traditional smart home systems often have problems such as security, data centralization and easy tampering, so a blockchain is an emerging technology that solves the problems. This paper proposes a blockchain-based smart home system which consists in a home and a blockchain network part. The blockchain network with 8 nodes is implemented by HyperLeger Fabric platform on Docker. ECC(Elliptic Curve Cryptography) technology is used for data transmission security and RBAC(role-based access control) manages the certificates of network members. Raft consensus algorithm maintains data consistency across all nodes in a distributed system and reduces block generation time. The query and data submission are controlled by the smart contract which allows nodes to safely and efficiently access smart home data. The experimental results show that the proposed system maintains a stable average query and submit time of 84.5 [ms] and 93.67 [ms] under high concurrent accesses, respectively and the transmission data is secured through simulated packet capture attacks.

Semen Analysis and Improvement of Artificial Seminal Plasma According to Sperm Activity in Eel Anguilla japonica (뱀장어(Anguilla japonica) 정자 활성에 따른 정액 분석 및 인공정장액 개선)

  • Han-Sik Kim;Shin-Kwon Kim;Bae-Ik Lee;Yongwoon Ryu;Min-Gyu Shin;Su-Jin Park;Youn-Hee Choi
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.56 no.4
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    • pp.401-410
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    • 2023
  • This study examined the characteristics of eel Anguilla japonica sperm using the CASA (computer-assisted sperm analysis) system and attempted to provide the composition for artificial seminal plasma by regulating of inorganic elements. Sperm samples were first divided into four groups based on motility and progressive motility: (A) 0-10%, (B) 10-40%, (C) 40-70%, and (D) 70-100%. For observing sperm velocity variations, VCL, which is curve motion velocity, showed the highest values in all groups. The directional factor, beat cross frequency, was lower in higher activity groups, showing an opposite correlation with sperm activity. The head sizes of spermatozoa in higher activity groups were significantly larger than those in lower activity groups. The Na+ and K+ ions were important in the inorganic composition of seminal plasma in this species. Furthermore, regulating the composition in artificial seminal plasma improved the formula compared to the existing element, exhibiting 120 mM Na and 30 mM K when the sperm was conserved for a long time and 120 mM NA and 40 mM K when the sperm was conserved for a short time.

Genome wide association study for growth in Pakistani dromedary camels using genotyping-by-sequencing

  • Sajida Sabahat;Asif Nadeem;Rudiger Brauning;Peter C. Thomson;Mehar S. Khatkar
    • Animal Bioscience
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    • v.36 no.7
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    • pp.1010-1021
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    • 2023
  • Objective: Growth performance and growth-related traits have a crucial role in livestock due to their influence on productivity. This genome-wide association study (GWAS) in Pakistani dromedary camels was conducted to identify single nucleotide polymorphisms (SNPs) associated with growth at specific camel ages, and for selected SNPs, to investigate in detail how their effects change with increasing camel age. This is the first GWAS conducted on dromedary camels in this region. Methods: Two Pakistani breeds, Marecha and Lassi, were selected for this study. A genotyping-by-sequencing method was used, and a total of 65,644 SNPs were identified. For GWAS, weight records data with several body weight traits, namely, birthweight, weaning weight, and weights of camels at 1, 2, 4, and 6 years of age were analysed by using model-based growth curve analysis. Age-specific weight data were analysed with a linear mixed model that included fixed effects of SNP genotype as well as sex. Results: Based on the q-value method for false discovery control, for Marecha camels, five SNPs at q<0.01 and 96 at q<0.05 were significantly associated with the weight traits considered, while three (q<0.01) and seven (q<0.05) SNP associations were identified for Lassi camels. Several candidate genes harbouring these SNP were discovered. Conclusion: These results will help to better understand the genetic architecture of growth including how these genes are expressed at different phases of their life. This will serve to lay the foundations for applied breeding programs of camels by allowing the genetic selection of superior animals.

The development of the seismic fragility curves of existing bridges in Indonesia (Case study: DKI Jakarta)

  • Veby Citra Simanjuntak;Iswandi Imran;Muslinang Moestopo;Herlien D. Setio
    • Structural Monitoring and Maintenance
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    • v.10 no.1
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    • pp.87-105
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    • 2023
  • Seismic regulations have been updated from time to time to accommodate an increase in seismic hazards. Comparison of seismic fragility of the existing bridges in Indonesia from different historical periods since the era before 1990 will be the basis for seismic assessment of the bridge stock in Indonesia, most of which are located in earthquake-prone areas, especially those built many years ago with outdated regulations. In this study, seismic fragility curves were developed using incremental non-linear time history analysis and more holistically according to the actual strength of concrete and steel material in Indonesia to determine the uncertainty factor of structural capacity, βc. From the research that has been carried out, based on the current seismic load in SNI 2833:2016/Seismic Map 2017 (7% probability of exceedance in 75 years), the performance level of the bridge in the era before SNI 2833:2016 was Operational-Life Safety whereas the performance level of the bridge designed with SNI 2833:2016 was Elastic - Operational. The potential for more severe damage occurs in greater earthquake intensity. Collapse condition occurs at As = FPGA x PGA value of bridge Era I = 0.93 g; Era II = 1.03 g; Era III = 1.22 g; Era IV = 1.54 g. Furthermore, the fragility analysis was also developed with geometric variations in the same bridge class to see the effect of these variations on the fragility, which is the basis for making bridge risk maps in Indonesia.

Numerical Model for Cerebrovascular Hemodynamics with Indocyanine Green Fluorescence Videoangiography

  • Hwayeong Cheon;Young-Je Son;Sung Bae Park;Pyoung-Seop Shim;Joo-Hiuk Son;Hee-Jin Yang
    • Journal of Korean Neurosurgical Society
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    • v.66 no.4
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    • pp.382-392
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    • 2023
  • Objective : The use of indocyanine green videoangiography (ICG-VA) to assess blood flow in the brain during cerebrovascular surgery has been increasing. Clinical studies on ICG-VA have predominantly focused on qualitative analysis. However, quantitative analysis numerical modelling for time profiling enables a more accurate evaluation of blood flow kinetics. In this study, we established a multiple exponential modified Gaussian (multi-EMG) model for quantitative ICG-VA to understand accurately the status of cerebral hemodynamics. Methods : We obtained clinical data of cerebral blood flow acquired the quantitative analysis ICG-VA during cerebrovascular surgery. Varied asymmetric peak functions were compared to find the most matching function form with clinical data by using a nonlinear regression algorithm. To verify the result of the nonlinear regression, the mode function was applied to various types of data. Results : The proposed multi-EMG model is well fitted to the clinical data. Because the primary parameters-growth and decay rates, and peak center and heights-of the model are characteristics of model function, they provide accurate reference values for assessing cerebral hemodynamics in various conditions. In addition, the primary parameters can be estimated on the curves with partially missed data. The accuracy of the model estimation was verified by a repeated curve fitting method using manipulation of missing data. Conclusion : The multi-EMG model can possibly serve as a universal model for cerebral hemodynamics in a comparison with other asymmetric peak functions. According to the results, the model can be helpful for clinical research assessment of cerebrovascular hemodynamics in a clinical setting.

Study on the performance indices of low-strength brick walls reinforced with cement mortar layer and steel-meshed cement mortar layer

  • Lele Wu;Caoming Tang;Rui Luo;Shimin Huang;Shaoge Cheng;Tao Yang
    • Earthquakes and Structures
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    • v.24 no.6
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    • pp.439-453
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    • 2023
  • Older brick masonry structures generally suffer from low strength defects. Using a cement mortar layer (CML) or steel-meshed cement mortar layer (S-CML) to reinforce existing low-strength brick masonry structures (LBMs) is still an effective means of increasing seismic performance. However, performance indices such as lateral displacement ratios and skeleton curves for LBMs reinforced with CML or S-CML need to be clarified in performance-based seismic design and evaluation. Therefore, research into the failure mechanisms and seismic performance of LBMs reinforced with CML or S-CML is imperative. In this study, thirty low-strength brick walls (LBWs) with different cross-sectional areas, bonding mortar types, vertical loads, and CML/S-CML thicknesses were constructed. The failure modes, load-carrying capacities, energy dissipation capacity and lateral drift ratio limits in different limits states were acquired via quasi-static tests. The results show that 1) the primary failure modes of UBWs and RBWs are "diagonal shear failure" and "sliding failure through joints." 2) The acceptable drift ratios of Immediate Occupancy (IO), Life Safety (LS), and Collapse Prevention (CP) for UBWs can be 0.04%, 0.08%, and 0.3%, respectively. For 20-RBWs, the acceptable drift ratios of IO, LS, and CP for 20-RBWs can be 0.037%, 0.09%, and 0.41%, respectively. Moreover, the acceptable drift ratios of IO, LS, and CP for 40-RBWs can be 0.048%, 0.09%, and 0.53%, respectively. 3) Reinforcing low-strength brick walls with CML/S-CML can improve brick walls' bearing capacity, deformation, and energy dissipation capacity. Using CML/S-CML reinforcement to improve the seismic performance of old masonry houses is a feasible and practical choice.

Leak Before Break Evaluation of Surge Line by Considering CPE under Beyond Design Basis Earthquake (설계초과지진시 CPE를 고려한 밀림관 파단전누설 평가)

  • Seung Hyun Kim;Youn Jung Kim;Han-geol Lee;Sun Yeh Kang
    • Transactions of the Korean Society of Pressure Vessels and Piping
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    • v.18 no.1
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    • pp.19-25
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    • 2022
  • Nuclear Power Plants (NPP) should be designed to have sufficient safety margins and to ensure seismic safety against earthquake that may occur during the plant life time. After the 9.12 Gyeongju earthquake accident, the structural integrity of nuclear power plants due to the beyond design basis earthquake is one of key safety issues. Accordingly, it is necessary to conduct structural integrity evaluations for domestic NPPs under beyond design basis earthquake. In this study, the Level 3 LBB (Leak Before Break) evaluation was performed by considering the beyond design basis earthquake for the surge line of a OPR1000 plant of which design basis earthquake was set to be 0.2g. The beyond design basis earthquake corresponding to peak ground acceleration 0.4g at the maximum stress point of the surge line was considered. It was confirmed that the moment behaviors of the hot leg and pressurized surge nozzle were lower than the maximum allowable loading in moment-rotation curve. It was also confirmed that the LBB margin could be secured by comparing the LBB margin through the Level 2 method. It was judged that the margin was secured by reducing the load generated through the compliance of the pipe.

Impact of monthly arteriovenous fistula flow surveillance on hemodialysis access thrombosis and loss

  • Ara Ko;Miyeon Kim;Hwa Young Lee;Hyunwoo Kim
    • Journal of Medicine and Life Science
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    • v.20 no.3
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    • pp.115-125
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    • 2023
  • Arteriovenous fistula flow dysfunction is the leading cause of vascular access thrombosis and loss in patients undergoing hemodialysis. However, data regarding the influence of access flow rate measurements on the long-term outcomes of access are limited. This study aims to identify accesses at a high risk of thrombosis and loss among patients undergoing hemodialysis by measuring the access flow rate and exploring an optimal threshold value for predicting future access thrombosis. We enrolled 220 patients with arteriovenous fistula undergoing hemodialysis. The primary outcome was the occurrence of access thrombosis. Access flow rates were measured monthly using the ultrasound dilution method and were averaged using all measurements from patients with patent access. In patients experienced access thrombosis, those immediately before the thrombosis were selected. Using these data, we calculated the access flow rate threshold for thrombosis occurrence by analyzing the receiver operating characteristic curve, and the patients were divided into two groups according to whether access flow rates were higher or lower than 400 mL/min. During a median follow-up period of 3.1 years, 4,510 access flows were measured (median measurements per patient, 33 times; interquartile range, 11-54). A total of 65 access thromboses and 19 abandonments were observed. Access thrombosis and loss were higher in the lowflow group than in the high-flow group. This study revealed that low access flow rates are strongly associated with access thrombosis occurrence and subsequent loss of arteriovenous fistulas in patients undergoing hemodialysis.

A Pungsu(Fengshui) Study on the Location of Traditional Residence of Gim Myeong-Gwan in Jeongeup (정읍 김명관고택 입지의 풍수고찰)

  • Han, Jong-Koo
    • Journal of the Korean Institute of Rural Architecture
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    • v.25 no.4
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    • pp.17-24
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    • 2023
  • This study is about the traditional house of Kim Myeong-Gwan, the founder of Gwangsan Kim clan(光山金氏) and the 30th grandson of Heunggwang, the 49th king of the Unified Silla Dynasty. He sought a place to take refuge due to a plot and built a house in Jeongeup, adjacent to Yeonsan or Nonsan, Chungcheong-do, which is the home of the Gwangsan Kim clan. The location of old houses was analyzed through Hyeongselon(形勢論) and hyeongguklong(形局論) of Pungsu theory. The results of fengshui analysis of the house through fengshui literature that was presumed to have been used at the time are as follows.The dragon(龍) shows an auspicious condition in which the dragon vein is well connected from its roots in the Honam vein to Guksabong Mountain on Josan Mountain, Bibongsan Mountain on Sojo Mountain, and Mt. Changhasan reaching Jusan Mountain. Hyeol(穴) is a type of Wahyeol(窩穴) and is a Hwalwa(濶窩). Hyeolseong(穴星) is a Jeongche-Hyeolseong(正體穴星) and is a Suseong Hyeol(水星穴). HyeolJung(穴證) and Hyeolgi(穴忌) have the conditions to create hyeol. As for Sa(砂), the height of Hyeonmu(玄武) is not that high, but the Jujak(朱雀) is relatively high, the left blue dragon(左靑龍) is complemented by the outer blue dragon(外靑龍), and the right white tiger(右白虎) does not sufficiently surround the house. To compensate for this, Bibosu trees(裨補樹) were planted at the time of the construction of the house. As for the Water element, it appears to be auspicious as it approaches the old house in the form of a curve, but it has the disadvantage of not sufficiently surrounding the house, so an artificial pond is dug as a Bibo Pungsu(裨補風水). Through this study, it was found that Pungsu was applied as an important consideration factore in selecting the location of the house, and that Pungsu was not just a theory but had a practical effect in preserving the life and property of the family under the risky circumstances of the time.

CT-Based Fagotti Scoring System for Non-Invasive Prediction of Cytoreduction Surgery Outcome in Patients with Advanced Ovarian Cancer

  • Na Young Kim;Dae Chul Jung;Jung Yun Lee;Kyung Hwa Han;Young Taik Oh
    • Korean Journal of Radiology
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    • v.22 no.9
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    • pp.1481-1489
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    • 2021
  • Objective: To construct a CT-based Fagotti scoring system by analyzing the correlations between laparoscopic findings and CT features in patients with advanced ovarian cancer. Materials and Methods: This retrospective cohort study included patients diagnosed with stage III/IV ovarian cancer who underwent diagnostic laparoscopy and debulking surgery between January 2010 and June 2018. Two radiologists independently reviewed preoperative CT scans and assessed ten CT features known as predictors of suboptimal cytoreduction. Correlation analysis between ten CT features and seven laparoscopic parameters based on the Fagotti scoring system was performed using Spearman's correlation. Variable selection and model construction were performed by logistic regression with the least absolute shrinkage and selection operator method using a predictive index value (PIV) ≥ 8 as an indicator of suboptimal cytoreduction. The final CT-based scoring system was internally validated using 5-fold cross-validation. Results: A total of 157 patients (median age, 56 years; range, 27-79 years) were evaluated. Among 120 (76.4%) patients with a PIV ≥ 8, 105 patients received neoadjuvant chemotherapy followed by interval debulking surgery, and the optimal cytoreduction rate was 90.5% (95 of 105). Among 37 (23.6%) patients with PIV < 8, 29 patients underwent primary debulking surgery, and the optimal cytoreduction rate was 93.1% (27 of 29). CT features showing significant correlations with PIV ≥ 8 were mesenteric involvement, gastro-transverse mesocolon-splenic space involvement, diaphragmatic involvement, and para-aortic lymphadenopathy. The area under the receiver operating curve of the final model for prediction of PIV ≥ 8 was 0.72 (95% confidence interval: 0.62-0.82). Conclusion: Central tumor burden and upper abdominal spread features on preoperative CT were identified as distinct predictive factors for high PIV on diagnostic laparoscopy. The CT-based PIV prediction model might be useful for patient stratification before cytoreduction surgery for advanced ovarian cancer.