• Journal of Microbiology and Biotechnology
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• v.17 no.8
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• pp.1330-1337
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• 2007

To better understand the gene expression of the cold-adapted polar diatom, we conducted a survey of the Chaetoceros neogracile transcriptome by cDNA sequencing and expression of interested cDNAs from the Antarctic diatom. A non-normalized cDNA library was constructed from the C. neogracile, and a total of 2,500 cDNAs were sequenced to generate 1,881 high-quality expressed sequence tags (ESTs) (accession numbers EL620615-EL622495). Based on their clustering, we identified 154 unique clusters comprising 342 ESTs. The remaining 1,540 ESTs did not cluster. The number of unique genes identified in the data set is thus estimated to be 1,694. Taking advantage of various tools and databases, putative functions were assigned to 939 (55.4%) of these genes. Of the remaining 540 (31.9%) unknown sequences, 215 (12.7%) appeared to be C. neogracile-specific since they lacked any significant sequence similarity to any sequence available in the public databases. C. neogracile consisted of a relatively high percentage of genes involved in metabolism, genetic information processing, cellular processes, defense or stress resistance, photosynthesis, structure, and signal transduction. From the ESTs, the expression of these putative C. neogracile genes was investigated: fucoxanthin chlorophyll (chl) a,c-binding protein (FCP), ascorbate peroxidase (ASP), and heat-shock protein 90 (HSP90). The abundance of ASP and HSP90 changed substantially in response to different culture conditions, indicating the possible regulation of these genes in C. neogracile.

• Korean Journal of Clinical Pharmacy
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• v.29 no.2
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• pp.115-124
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• 2019

The purpose of this systematic review and meta-analysis was to assess the preventive effect of theophylline on acute kidney injury and the ameliorative effect of theophylline on renal function in asphyxiated neonates. A literature search of the PubMed/Medline, Embase, and Cochrane Library databases for information published up to February 2019 was conducted. All studies that reported the incidence rate of acute kidney injury, serum creatinine level, and glomerular filtration rate after the randomized administration of theophylline or placebo were included. In total, eight studies involving 498 neonates were eligible. The incidence rate of acute kidney injury was significantly lower in the theophylline group than in the placebo group (risk ratio [RR]: 0.42, 95% confidence interval [CI]: 0.32-0.55, p < 0.001). The changes in serum creatinine level in the theophylline group were significantly higher than those in the placebo group from the first day of life to 3 and 5 days of age (weighted mean difference [WMD]: -0.51, 95% CI: -0.62 to -0.40, p < 0.001, and WMD: -0.26, 95% CI: -0.34 to -0.18, p < 0.001, respectively). The changes in glomerular filtration rate in the theophylline group were significantly higher than those in the placebo group from the first day of life to 3 days of age and the last day of follow-up (WMD: 12.30, 95% CI: 9.39-15.21, p < 0.001, and WMD: 9.35, 95% CI: 6.43-12.27, p < 0.001, respectively). These results suggested that theophylline has a beneficial effect on the prevention of acute kidney injury in neonates with perinatal asphyxia.

• Journal of Korean Traditional Oncology
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• v.17 no.2
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• pp.1-16
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• 2012

Background : Integrative cancer treatment is a holistic approach embracing body, mind, and spirit incorporating conventional treatments of surgery, chemotherapy, radiation and personalized complementary treatments. Wheel Balance Therapy (WBT) of East-West Cancer Center(EWCC), Dunsan Oriental Hospital of Daejeon University was developed to balance out all factors involved in cancer care based on the traditional theories of oriental medicine. Objective : This work aims to analytically review literatures on WBT and its related components. Methods : Literatures published from January 1st, 1990 to April 30th, 2011 were reviewed focusing on 4 main components of WBT; herbal medicine, immune activation, anti-cancer diet, and breathing/meditation. Data were retrieved from medical search engines and electronic data bases including Pubmed, Research Information sharing Service (RISS), Korean-studies Information Service System (KISS), China National Knowledge Infrastructure (CNKI), and Korea's National Digital Library (KNDL). Results : In this review, EWCC's most commonly prescribed formulas are explored. The composition of the formulas, their use in clinical settings as well as the background studies and other therapeutic efficacies are explained. Information on incorporating anti-cancer dietary support and breathing and meditation techniques, other therapies practiced as part of the center's integrative cancer care are also covered. Conclusion : WBT based on holistic theories of oriental medicine embracing body, mind, and spirit is expected to further contribute in promotion of cancer patients' quality of life and prolonged survival time.

• The KIPS Transactions:PartA
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• v.13A no.7 s.104
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• pp.561-572
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• 2006

Performance of the mobile devices greatly depends on the efficient resource management because they are usually resource-restricted. In particular, the dynamic storage allocation algorithms very important part of the mobile device's operating system and OS-like software platform. The existing dynamic storage allocation algorithms did not consider application's execution style and the type, life-time, and characteristics of memory objects that the application uses. Those algorithms, as a result, could not manage memory efficiently Therefore, this Paper analyzes the mobile application's execution characteristics and proposes anew dynamic storage allocation algorithm which saves the memory space and improves mobile application's execution speed. The test result shows that the proposed algorithm works 6.5 times faster than the linked-list algorithm[11], 2.5 times faster better than the Doug. Lea's algorithm[12] and 10.5 times faster than the Brent algorithm[14].

• Journal of the Computational Structural Engineering Institute of Korea
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• v.30 no.3
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• pp.223-230
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• 2017

BIM(building information modeling) has been actively applied to construction industries and to maximize its application through the life cycle of structure, various relevant technologies have been proposed. In particular, 4D sequencing management and 5D cost-related management were introduced as an improved version of the design review and interface control by 3D information design. On the other hand, the virtual construction using virtual construction equipment can sophisticatedly handle capacity, dynamic movement, collision boundaries of actual construction machines but it still stays at a low level in a technical sense. In this study, simulation systems based on BIM involving virtual construction equipment have been developed; then it is applied to the actual construction project to evaluate the safety and efficiency of construction equipments. It was confirmed that the simulation systems can be utilized to construct virtual construction site by using an effective 3D library of construction equipment and can plays a key role to secure construction safety and economic feasibility. Specifically, the simulation system are very useful for decision making by construction managers to select the optimum equipment and construction method with a better understanding for safety and cost-saving.

• Journal of the Korea Society of Computer and Information
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• v.19 no.8
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• pp.197-205
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• 2014

The purpose of this study is to analyse on the internet use of Korean older adults focused on their socioeconomic characteristics. For this study, data were collected through the face to face interview with aged over 60 using a questionnaire for the residence of Daegu and Kyungsang Buk-Do areas. Subjects were divided into socioeconomic characteristics such as gender, education level, economic level, religion, and life satisfaction. The data were analysed the elderly's internet use such as frequency of internet access, motivation of internet use, utilization of internet, and usefulness of internet based on their socioeconomic characteristics. The results of this empirical study revealed that there exist a significant differences between internet use and socioeconomic characteristics in elderly people. It is hoped that the results of this study provide an essential data for developing the policy of the elderly's digital divide and welfare.

• Journal of Industrial Convergence
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• v.20 no.1
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• pp.43-51
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• 2022

The purpose of this study is to provide basic information necessary for the establishment of mobile service marketing strategies, educational service development, and engineering education for Generation Z by analyzing the utilitization of various applications by Gen Z. To this end, 177 essays on mobile service usage experience were collected, major topics were analyzed using topic modeling, and these were visualized through word cloud analysis. As a result of the study, the main topics were related to 'transportation' such as movement and public transportation, 'personal management' such as schedule management, financial management, food management, 'transaction' such as checkout, meeting, purchase, 'leisure' such as eating out, travel, study, culture. Additionally, words such as time, thought, people, life, bus, information, confirmation, payment, KakaoTalk, and so on were found to have a high of frequency of use. Also, there was found to be a difference between topics by college. This study is meaningful in that it collected essays, which are unstructured data, and analyzed them through topic modeling.

• Journal of Life Science
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• v.18 no.11
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• pp.1507-1512
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• 2008

In spite of long research period for Salmonella typhi, little information is known about the pathogenesis mechanism of human typhoid fever caused by S. typhi due to lack of infection model in animals. A wild-type of S. typhi Ty2 strain requires cysteine to grow on minimal media. We hypothesized that this cysteine requirement may restrict colonization of S. typhi in animals during infection process. Among the S. typhi strains carrying Salmonella typhimurium genomic library, we have isolated three S. typhi transformants growing on minimal media without cysteine. Although there were three ORFs in DNA of pBP71, the STM1490 ORF complemented cysteine auxotrophy of S. typhi. Analysis of the deduced amino acid sequence of the STM1490 homolog in S. typhi revealed that there are differences in two amino acids. Plasmids containing amino acid substitutions in STM1490 supported S. typhi growth on minimal media without cysteine, indicating irrelevance of these two amino acids to STM1490 function. These results tells us that there are other factors or systems involved in cysteine requirement of S. typhi.

• Journal of the Korean Society for Library and Information Science
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• v.49 no.3
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• pp.209-231
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• 2015

The main purpose of this study is to develop and apply a means of connecting reading movement and Newspaper In Education (NIE) activities utilizing the voluntary participation and cooperation of local school districts and autonomous government entities. This is necessary to revitalize or systematize the environmental social life of reading newspapers and NIE activity. Literary or inquiry research will be initiated in this study in order to quantify the current or actual conditions of this connection, delineating the basic objectives of this study, and determining the developmental directions for continuing this study as related to the connection of reading movement and NIE activity. Anticipated study activities or major tasks are as follows. First, develop a variety of intended programs and learning materials necessary for each. Secondly, develop and establish corresponding online data and educational programs. Thirdly, a "cooperation" system must be established and training programs implemented reinforcing these ideas. And, lastly (and to gain wider acceptance), starting a public relations campaign to show or illustrate the benefits of this study and these intended research activities. In conclusion, if a connection between reading movement and NIE activity are fully established and periodically adjusted by means of continuing discussions on the merits or concerns based on the study findings, the full potential of the reading movement connection with NIE activity will be realized and achieved to its truest meaning and/or highest order.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.30 no.2
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• pp.69-87
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• 2019

As the discussions on sharing research data prevail by the chance of the inauguration of the International Open Data Charter, research support organizations in the United States, the United Kingdom, and Japan are encouraging researchers to deposit their findings in a credible repository. Humanities and social sciences field, in which research data sharing culture and storage infrastructure are immature compared to life science and natural science, also needs to establish and operate a reliable storage infrastructure to guarantee the continuous access and utilization of data. This study analyzed the overall operational status of 305 subject repositories registered in re3data for the humanities and social sciences and clustered them according to the operational level using 5 indicators. As a result, 70% of the population were identified as universal clusters, and 20% of the excellent cluster was found to have the largest number of linguistic fields and the German-operated. In addition, this study confirmed through correspondence analysis that there is a relation between the sub-theme fields of humanities and social sciences and the types of data to be archived. The history and art domians are related to images, and social studies are related to statistical data. Linguistics has also been analyzed to be related to audio, plain text, and code.