• Transactions of the Korean Society of Automotive Engineers
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• v.16 no.6
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• pp.109-114
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• 2008

An improvement of vehicle fuel economy is one of the most important topic in automotive engineering. Lots of engineers make efforts to achieve 1% of fuel economy improvement. Engine friction is an important factor influencing vehicle fuel economy. This paper focuses on effect of engine friction on vehicle fuel economy during warm-up. A computer simulation is one of the powerful tools in automotive engineering field. Recently Simulation is attempting to virtual experiment not using expensive instruments. It is possible to presuppose fuel economy by changing the characteristic of accessories using CRUISE(vehicle simulation software). In this paper, fuel consumption at each part of the vehicle is analyzed by both of experiment and simulation. The results of fuel economy analysis on experiment substitute for Cruise to calculate fuel economy. The simulation data such as engine speed, brake torque, shift pattern, vehicle speed, fuel consumption level is well correlated to experiment data. In this paper, the change of warm-up time, faster or slower, through simulation is performed. As a result of the fast warm-up, fuel economy is improved up to 1.7%.

• Journal of the Korean Society of Marine Environment & Safety
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• v.21 no.6
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• pp.721-728
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• 2015

Due to paradigm shift in administration, the field of police administration, like its civilian counterpart, is spending effort to improve customer-oriented civil complaint service system, and this is leading to a negative factor in service providers, emotional labor, among police officers. This study examines amount of emotional labor of maritime police officers, and verify the effects of emotional labor on exhaustion. Results show maritime police officers experience about the same amount of emotional labor as other public workers, and emotional labor has effects on work exhaustion. In other words, perception of incongruity of emotion has positive effects on exhaustion on cynical attitude. Attention to emotional expression has negative effects on decrease of job effectiveness. As such, if the problem of emotional labor is neglected, it leads to exhaustion and can become a significant obstacle to performance due to negative organizational influence. Also, it can lead to serious physical and mental problems on the individual level. Therefore, policy implementation to prevent this problem is necessary.

• Archives of Pharmacal Research
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• v.27 no.5
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• pp.524-530
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• 2004

Epilepsy or the occurrence of spontaneous recurrent epileptiform discharges (SREDs, seizures) is one of the most common neurological disorders. Shift in the balance of brain between excitatory and inhibitory functions due to different types of structural or functional alterations may cause epileptiform discharges. N-Methyl-D-aspartate (NMDA) receptor dysfunctions have been implicated in modulating seizure activities. Seizures and epilepsy are clearly dependent on elevated intracellular calcium concentration ([C $a^{2+}$]$_{i}$ ) by NMDA receptor activation and can be prevented by NMDA antagonists. This perturbed [C $a^{2+}$]$_{i}$ levels is forerunner of neuronal death. However, therapeutic tools of elevated [C $a^{2+}$]$_{i}$ level during status epilepticus (SE) and SREDs have not been discovered yet. Our previous study showed fast inhibition of ginseng total saponins and ginsenoside R $g_3$ on NMDA receptor-mediated [C $a^{2+}$]$_{i}$ in cultured hippocampal neurons. We, therefore, examined the direct modulation of ginseng on hippocampal neuronal culture model of epilepsy using fura-2-based digital $Ca^{2+}$ imaging and neuronal viability assays. We found that ginseng total saponins and ginsenoside R $g_3$ inhibited $Mg^{2+}$ free-induced increase of [C $a^{2+}$]$_{i}$ and spontaneous [C $a^{2+}$]$_{i}$ oscillations in cultured rat hippocampal neurons. These results suggest that ginseng may playa neuroprotective role in perturbed homeostasis of [C $a^{2+}$]$_{i}$ and neuronal cell death via the inhibition of NMDA receptor-induced SE or SREDs.d SE or SREDs..

• Journal of the Korean Chemical Society
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• v.37 no.8
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• pp.735-743
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• 1993

The electrocatalytic reduction of oxygen is investigated by cyclic voltammetry and chronoamperometry at glassy carbon electrode and carbon microelectrode coated with a variety of cobalt phenylprophyrins in various pH solutions. Oxygen reduction catalyzed by the monomeric porphyrin Co(Ⅱ)-TPP mainly occurs through the 2e$^-$ reduction pathway resulting in the formation of hydrogen peroxide whereas electrocatalytic process carried out 4e$^-$ reduction pathway of oxygen to H$_2$O at the electrodes coated with cofacial bis-cobalt phenylporphyrins in acidic solution. The electrocatalytic reduction of oxygen is irreversible and diffusion controlled. The reduction potentials of oxygen in various pH solutions have a straight line from pH 4 to pH 13, but level off in strong acidic solution. The reduction potentials of oxygen shift to positive potential more 400 mV at the electrode coated with monomer Co-TPP compound than bare glassy carbon electrode while 750 mV at the electrode coated with dimer Co-TPP compound.

• Atmosphere
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• v.27 no.2
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• pp.177-188
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• 2017

The development mechanisms of an unusual heavy snowfall event, which occurred in the coast of Jeju Island on 23 January 2016 were investigated through a thermodynamic approach. The formation of heavy snowfall was attributed to the enhanced thermal convection in two ways. First, the convection was enhanced by the air-sea temperature difference between the cold air advection in low-troposphere associated with the strengthening of the Siberian High and abnormal warm sea surface temperature, which is $1{\sim}2^{\circ}C$ higher than normal year over the Yellow Sea (YS). Second, the convective instability was increased by the vertical temperature gradient between the 7 days-sustained cold air advection in low-troposphere and the abrupt cold air intrusion in mid-troposphere induced by the southward shift of a cold cut-off vortex ($-45^{\circ}C$) at the formation stage. Compared to the twelve hours prior to the formation, the low-level moisture increased by 5% through the moisture supply from the YS, and the air-sea temperature difference increased from $18.5^{\circ}C$ to $28.5^{\circ}C$. Furthermore, the upward sensible (latent) heat flux increased 1.5 (1.2) times over the YS before the twelve hours prior to the formation. Thereafter, the sustained moisture supply and upward turbulent heat flux helped to maintain the snowstorm.

• Journal of Biomedical Engineering Research
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• v.20 no.3
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• pp.299-305
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• 1999

In thls paper, the representative beal textraction algorIthms for the diagnostic parameter extraction in noisy signal were compared. We used the avernge, median, mode, and trmmed mean to calculale the central tendency. In our experimenl, we have restricted to four kinds of noises -EMG noise, 60Hz powerline inlerference, ahrupl baseline shift, and baselme drift due to respimtion-which were commonly occurred in ECG mgnal, then we have calculated signal-to-noise ratios(SNRs) for the ECG corrupted with each noise and all noises together. As the result of this paper, we have proved that the average method has super lor performance than the others in the ECG corrupted wilh EMG noise. When the signal mcludes extreme value such as abrupt baseline shIft, the median, mode, trimmed mean methods have supenor performance in the SNR ratios. Especially when the ECG corrupted with baseline drift due to respirallon, the trimmed mean method was most efficient because ST level change was 0 V.

• The Korean Journal of Physiology
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• v.20 no.2
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• pp.165-174
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• 1986

The voltage clamp studies were undertaken to elucidate the properties of the slow inward current, $i_{si}$, in the small preparations of the rabbit sinoatrial node. The slow inward current, $i_{si}$, which is known to be responsible for the late one-third of pacemaker potential and whole range of upstroke phase of action potential was analysed with the effects of isoprenaline, cobalt, ouabain and higenamine. The results obtained are as follows; 1) Voltage of SA node preparation was held at zero current level, usually-40mV and the slow inward current, $i_{si}$, was activated by depolarizing clamp pulses. Peak values of $i_{si}$, in steady state were at $-10{\pm}0mV$ in most preparations. 2) Isoprenaline, ${\beta}-agonist$ increased $i_{si}$ and no shift was noticed in voltage-dependency. 3) Cobalt ion in the concentration of 1 mM abolished is, in entire range of membrane potential and the difference of two current levels before and after $Co^{2+}$ treatment could be considered as pure $i_{si}$ magnitude. 4) In the therapeutic concentration of ouabain $(5{\times}10^{-8}M)$ slightly increased is, and reduced the time to reach the peak value. 5) Higenamine $(10^{-6}M)$ changed the configurations of action potential (i. e. rapid upstroke phase and notch in the spike) and increase spontaneous rate. It also increased is, and the effect of higenamine was blocked ${\beta}-blocker$, propranolol $(10^{-6}M)$.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.11
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• pp.1049-1057
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• 2020

The shift from elite education to mass education in Vietnam has met the demand for education for everybody as well as for quality human resource talent for an emerging nation. Under the resource constraint, understanding the quality dimensions of education and its priority level is important for effective and efficient policies. This study was carried out using both qualitative and quantitative methodologies to develop quality criteria and a ranking model. Two rounds of in-depth interviews were conducted with fifteen experts in the field, who were rectors, employers, and recruitment specialists to develop the quality framework applied in Vietnamese universities under total quality management (TQM), starting from the input of the senior secondary school leavers, through a teaching process to the output. The first round of interviews were unstructured questionnaires designed to explore the main factors in quality assessment model. The second round affirmed the experts' agreement on the assessment model. Then, fuzzy logic was applied to rank eight criteria in the quality assessment model into priority order: cost, teaching and administrative staff, leadership, curriculum, student-related factors, internationalization, admissions, and campus. The results are critical for identifying the necessary actions to enhance the education quality and to further research on the optimal quality model.

• Archives of Pharmacal Research
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• v.11 no.1
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• pp.33-40
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• 1988

Two new nitro analogs of tranylcypromine, (E)-2-(p-nitrophenyl)cyclopropylamine ((E)-p-NTCP) and (E)-2-(m-nitrophenyl)cyclopropylamine ((E)-m-NTCP) were synthesized in order to examine the effect of aromatic nitro substitution on the MAO-inhibitory activity of 2-phenylcyclopropylamines. The compounds were obtained by treating t-butyl (E)-2-(p-nitrophenyl) cyclopropanecarbamate and t-butyl (E)-2-(m-nitrophenyl)cyclopropanecarbamate with p-toluenesulfonic acid in $CH_3$CN. Inhibitions of rat brain mitochondrial MAO-A and B by the compounds were examined using serotonin and benzylamine as the substrate at both in vitro and ex vivo levels. It was found from in vitro measurements that (E)-p-NTCP at $6.0{\times}10^{-5}M$ elicited merely 22.5% inhibition against MAO-B without any effect on MAO-A. In contrast, (E)-m-NTCP showed fair degrees of inhibitions of MAO-A and B with $IC_{50}$ values, $2.5{\times}10^{-7}M\;and\;1.4{\times}10^{-6}M$, respectively. It was also noted from (E)-m-NTCP that m-nitro substitution caused a shift of selectivity of the inhibition toward MAO-A. According to ex vivo measurements at 1.5, 3, 6, and 12 hr following the administration of a dose of 0.015 mmol/kg, i.p. to the rats, the inhibition percents of MAO-A by (E)-m-NTCP were 58.6, 63.7 63.6, and 46.6%, slightly lower than those observed by tranylcypromine. Whereas, (E)-m-NTCP at the same dose level did not show significant inhibitions against both MAO-A and MAO-B. Possible reasons for the difference in potencies between (E)-m-NTCP and (E)-p-NTCP were sought in relation to differing electron withdrawing effects of m- and p-substituents which will influence electron density of the side chain amino functions and the partitions.

• Journal of Korean Clinical Nursing Research
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• v.20 no.1
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• pp.15-27
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• 2014

Purpose: The purpose of this study was to identify nurse's intention to keep current job in the hospital. Methods: Data were collected from 1,143 nurse's working in over 300 beds hospital. The questionnaire with 47 items was developed by researchers to measure nurse's intention to keep his/her current nursing job in hospital. The questionnaire was developed through a focus group interview asking nurse's about their work experiences and literature review, and validated by researchers. Using descriptive statistics, data were analyzed in frequency and severity of nurse's intention to keep nursing job. The Cronbach's ${\alpha}$ of the questionnaire was .906. Results: The mean score of nurse's intention to keep current nursing job was 2.66. The highest mean scores of item of nurse's intention to keep nursing job was "as a nurse it is my duty to help others" ($3.19{\pm}0.45$), and the lowest was "the rotating shift helps me doing housework and raise for my kids" ($1.77{\pm}0.64$). And there are significant differences between period of working (F=9.71, p<.001), current position (F=5.91, p<.001), educational level (F=13.44, p<.001), and impulse experience of changing a job (F=71.20, p<.001). Conclusion: The findings of this study showed possibilities to develop programs for heightening the pride of professional nurse and increasing nurse's intention to keep nursing job in order to increase nurse's professional satisfaction and achievement.