• Title/Summary/Keyword: Level set methods

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Features of Implementing Pedagogical Practices on the Example of EU Countries' Experience

  • Mykhailo Poplavskyi
    • International Journal of Computer Science & Network Security
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    • v.24 no.2
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    • pp.129-135
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    • 2024
  • Studying at a modern university involves using modern methods and the latest advances in science and education, which applies to Ukraine and all higher education institutions in Europe, determining the relevance of the study and its international significance. The study aims to analyze and implement effective and innovative practices that can be used in integrated educational programs, which include interactive work in education at the European level. The use of general scientific approaches, such as theoretical, statistical, and empirical, allows achieving the set goals. The central hypothesis of the research is the presentation of the best pedagogical practices in the educational program, which includes interactive and universal. The results of the study prove the effectiveness of interactive training. Future research is devoted to developing new pedagogical practices and the development of algorithms for their implementation.

Postgraduate Students’ Use of E-Resources in Nigerian University Libraries: What is the Influence of User Education?

  • Abubakar, Daniel;Adetimirin, Airen
    • Journal of Information Science Theory and Practice
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    • v.4 no.3
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    • pp.43-56
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    • 2016
  • Introduction. Inadequate methods for acquiring user education could affect the level of library user education possessed by postgraduate students, and ultimately influence the purposes of their usage of e-resources provided in their university libraries. Despite the global acceptance that e-resources are contributing to postgraduate student’s research work, however, it has been documented that there is low use of e-resources in university libraries in Nigeria among postgraduate students. This drift could have negative consequences on their overall development. Therefore, this study determined how influential library user education is on the use of e-resources by postgraduate students in Nigerian university libraries.Methods. A survey research design and multi-stage sampling technique was adopted to select 2,726 from 54,578 postgraduate students from four faculties in 16 federal conventional universities in Nigeria. The data set was collected using a questionnaire and an interview schedule for e-resources librarians/system librarians and was analysed using percentage and Pearson’s product moment correlation.Results. The majority of the students were at the Master’s level (57.5%). The gender shows a ratio of 59.0% male and 41.0% female. Most Nigerian students enrol for postgraduate programmes in their thirties ‘30-39’ years. The use of e-resources by the postgraduates was low (weighted average of 2.45). The relationship between level of library user education and postgraduate students’ use of e-resources was positive, slightly strong, and significant (r = 318; df = 2284; p< .05).Conclusion. User education has positively inclined postgraduate students to the use of e-resources in their libraries. Therefore, libraries should employ all methods for acquiring user education for postgraduate students.

The Quality Performance Management of CMMI in the Era of Industry 4.0 (4차 산업혁명 시대의 CMMI 품질성과관리 연구)

  • Cho, Kyoung-Shik;Shin, Wan Seon
    • Journal of Korean Society for Quality Management
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    • v.47 no.1
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    • pp.17-32
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    • 2019
  • Purpose: CMMI is a process model used to assess or improve an organization's software development capabilities. This paper deals with the quality indicators when using CMMI and their priorities for possible improvement. Methods: The 22 process areas and 167 practices of CMMI are matched with 60 indicators of Quality Scorecard(QSC) first to analyze the balance of CMMI in terms of prevention, appraisal, and final result categories and second to isolate a set of key areas for quality focused performance measures. Results: A total of 86.2% (144 out of 167) CMMI practices were mapped to QSC. According to the CMMI level of maturity, level 2 and 3 accounted for more than 75% of the total. The practices at the maturity level of 4 and 5 were mapped to more than 52% of the final result's measurements. It has been observed that CMMI practices need further elaboration at higher levels to consider prevention, appraisal, and final results simultaneously. Conclusion: In order to improve the quality performance of the organization by applying CMMI, the final result measures should be refined in metrics, cycles, and methods, and then corrective actions could be conducted to improve the performance of CMMI practices. This strategy would help the practitioners benefit from CMMI in fostering the overall quality level of key activities for the organization's business goals.

Effect of Dietary Lifestyle of the Elderly on the Health-Related Quality of Life: Based on the 2011-2020 Korea national health and nutrition examination survey (노인의 식생활 형편이 건강관련 삶의 질에 미치는 영향: 2011-2020년 국민건강영양조사 자료를 이용하여)

  • Hyun-Jung Jung;Ji-Kyeong Park
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.4
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    • pp.199-211
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    • 2023
  • Purpose : Rapid population aging in South Korea is emerging as serious social problems, and interest in the health-related quality of life of the elderly is also increasing. Therefore, this study attempted to provide basic data to develop measures to improve the health-related quality of life of the elderly by identifying the impact of the elderly's dietary lifestyle on the health-related quality of life. Methods : Utilizing raw data from the Korea national health and nutrition examination survey spanning from 2011 to 2020, this study focused on individuals aged 65 and above. After excluding cases with missing data, 12,731 individuals were included in the final analysis. Various statistical methods including frequency analysis, t-tests, ANOVA, Scheffé test and hierarchical regression analysis were performed using SPSS 25.0 for windows. The statistical significance level (α) was set at .05. Results : The main results of this study were as follows. Firstly, dietary lifestyle exhibited variations depending on gender, age, education level, individual income, basic livelihood type, household type, self-rated health status, and chewing difficulty (p<.001). Secondly, there were disparities in health-related quality of life (as measured by the EQ-5D index) based on gender, age, education level, residence, individual income, basic livelihood security, self-rated health status, and chewing difficulty (p<.001). Thirdly, the EQ-5D index showed that elderly individuals' dietary lifestyle adversely impacted their health-related quality of life (F=353.74, p<.001). Conclusion : Therefore, it is necessary to prepare policies to improve the health-related quality of life by maintaining a proper diet for the elderly, and customized support and management is required taking into account the elderly's gender, age, education level, individual income, basic livelihood security, household type, self-rated health status, chewing difficulty etc.

Development of a Malignancy Potential Binary Prediction Model Based on Deep Learning for the Mitotic Count of Local Primary Gastrointestinal Stromal Tumors

  • Jiejin Yang;Zeyang Chen;Weipeng Liu;Xiangpeng Wang;Shuai Ma;Feifei Jin;Xiaoying Wang
    • Korean Journal of Radiology
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    • v.22 no.3
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    • pp.344-353
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    • 2021
  • Objective: The mitotic count of gastrointestinal stromal tumors (GIST) is closely associated with the risk of planting and metastasis. The purpose of this study was to develop a predictive model for the mitotic index of local primary GIST, based on deep learning algorithm. Materials and Methods: Abdominal contrast-enhanced CT images of 148 pathologically confirmed GIST cases were retrospectively collected for the development of a deep learning classification algorithm. The areas of GIST masses on the CT images were retrospectively labelled by an experienced radiologist. The postoperative pathological mitotic count was considered as the gold standard (high mitotic count, > 5/50 high-power fields [HPFs]; low mitotic count, ≤ 5/50 HPFs). A binary classification model was trained on the basis of the VGG16 convolutional neural network, using the CT images with the training set (n = 108), validation set (n = 20), and the test set (n = 20). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated at both, the image level and the patient level. The receiver operating characteristic curves were generated on the basis of the model prediction results and the area under curves (AUCs) were calculated. The risk categories of the tumors were predicted according to the Armed Forces Institute of Pathology criteria. Results: At the image level, the classification prediction results of the mitotic counts in the test cohort were as follows: sensitivity 85.7% (95% confidence interval [CI]: 0.834-0.877), specificity 67.5% (95% CI: 0.636-0.712), PPV 82.1% (95% CI: 0.797-0.843), NPV 73.0% (95% CI: 0.691-0.766), and AUC 0.771 (95% CI: 0.750-0.791). At the patient level, the classification prediction results in the test cohort were as follows: sensitivity 90.0% (95% CI: 0.541-0.995), specificity 70.0% (95% CI: 0.354-0.919), PPV 75.0% (95% CI: 0.428-0.933), NPV 87.5% (95% CI: 0.467-0.993), and AUC 0.800 (95% CI: 0.563-0.943). Conclusion: We developed and preliminarily verified the GIST mitotic count binary prediction model, based on the VGG convolutional neural network. The model displayed a good predictive performance.

Molecular authentication of Lepidii seu Descurainiae Semen by the development of matK amplification primers and analysis of sequences (matK 증폭용 primer 개발 및 염기서열 분석을 통한 정력자(葶藶子) 유전자 감별)

  • Moon, Byeong Cheol;Kim, Wook Jin;Yang, Sungyu;Park, Inkyu;Yeo, Sang Min;Noh, Pureum
    • The Korea Journal of Herbology
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    • v.33 no.3
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    • pp.25-35
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    • 2018
  • Objectives : Lepidii seu Descurainiae Semen has been frequently adulterated with the seeds of several inauthentic plant species. However, the accurate identification of these plant seeds is very difficult. To develop a reliable genetic authentication tool for Lepidii seu Descurainiae Semen, we analyzed matK sequence. Methods : To obtain the matK sequences of plant materials, genomic DNA was extracted from 24 samples and PCR amplification was carried out using matK-AF/matK-8R universal primer set and matK-LDSF/matK-LDSR primer set. For identifying species-specific nucleotides and phylogenetic analysis, matK regions were sequenced and comparatively analyzed by the ClustalW and Maximum Likelihood method. Results : We developed a new primer set to amplify matK region in Lepidii seu Descurainiae Semen and closely related plant samples. From the comparative analysis of matK sequences, we identified species-specific marker nucleotides for D. sophia, L. apetalum, L. latifolium, E. cheiranthoides, E. macilentum, and D. nemorosa, respectively. Furthermore, phylogenetic analysis revealed clear classification depending on the species. These results indicated that the matK sequence obtained a new primer set in this study was useful to identify Lepidii seu Descurainiae Semen in species level. Conclusions : We developed a primer set and identified species-specific marker nucleotides enough to distinguish authentic Lepidii seu Descurainiae Semen and adulterants at the species level based on the matK sequences. These genetic tool will be useful to prevent adulteration and to standardize the quality of Lepidii seu Descurainiae Semen.

Meaning and Definition of Partial Charges (부분 전하의 의미와 정의)

  • Cho, Seung Joo
    • Journal of Integrative Natural Science
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    • v.3 no.4
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    • pp.231-236
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    • 2010
  • Partial charge is an important and fundamental concept which can explain many aspects of chemistry. Since a molecule can be regarded as neclei surrounded by electron cloud, there is no way to define a partial charge accurately. Nevertheless, there have been many attempts to define these seemingly impossible parameters, since they would facilitate the understanding of molecular properties such as molecular dipole moment, solvation, hydrogen bonding, molecular spectroscopy, chemical reaction, etc. Common methods are based on the charge equalization, orbital occupancy, charge density, and electric multipole moments, and electrostatic potential fitting. Methods based on the charge equalization using electronegativity are very fast, and therefore they have been used to study many compounds. Methods to subdivide orbital occupancy using basis set conversion, relies on the notion that molecular orbitals are composed of atomic orbitals. The main idea is to reduce overlap integral between two nuclei using converted orthogonal basis sets. Using some quantum mechanical observables like electrostatic potential or charge multipole moments. Using potential grids obtained from wavefunction, partial charges can be fitted. these charges are most useful to describe intermolecular electrostatic interactions. Methods to using dipole moment and its derivatives, seems to be sensitive the level of theory, Dividing electron density using density gradient being the most rigorous theoretically among various schemes, bears best potential to describe the charge the most adequately in the future.

Multiple Linkage Disequilibrium Mapping Methods to Validate Additive Quantitative Trait Loci in Korean Native Cattle (Hanwoo)

  • Li, Yi;Kim, Jong-Joo
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.7
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    • pp.926-935
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    • 2015
  • The efficiency of genome-wide association analysis (GWAS) depends on power of detection for quantitative trait loci (QTL) and precision for QTL mapping. In this study, three different strategies for GWAS were applied to detect QTL for carcass quality traits in the Korean cattle, Hanwoo; a linkage disequilibrium single locus regression method (LDRM), a combined linkage and linkage disequilibrium analysis (LDLA) and a $BayesC{\pi}$ approach. The phenotypes of 486 steers were collected for weaning weight (WWT), yearling weight (YWT), carcass weight (CWT), backfat thickness (BFT), longissimus dorsi muscle area, and marbling score (Marb). Also the genotype data for the steers and their sires were scored with the Illumina bovine 50K single nucleotide polymorphism (SNP) chips. For the two former GWAS methods, threshold values were set at false discovery rate <0.01 on a chromosome-wide level, while a cut-off threshold value was set in the latter model, such that the top five windows, each of which comprised 10 adjacent SNPs, were chosen with significant variation for the phenotype. Four major additive QTL from these three methods had high concordance found in 64.1 to 64.9Mb for Bos taurus autosome (BTA) 7 for WWT, 24.3 to 25.4Mb for BTA14 for CWT, 0.5 to 1.5Mb for BTA6 for BFT and 26.3 to 33.4Mb for BTA29 for BFT. Several candidate genes (i.e. glutamate receptor, ionotropic, ampa 1 [GRIA1], family with sequence similarity 110, member B [FAM110B], and thymocyte selection-associated high mobility group box [TOX]) may be identified close to these QTL. Our result suggests that the use of different linkage disequilibrium mapping approaches can provide more reliable chromosome regions to further pinpoint DNA makers or causative genes in these regions.

Molecular Markers for the Rapid Detection of Colletotrichum coccodes, an Anthracnose Pathogen of Tomato (토마토 탄저병균 Colletotrichum coccodes 신속 검출 분자 마커)

  • Kim, Jun Young;Woon, Jang Si;Kim, Hyun Ju;Kim, Seong Hwan
    • The Korean Journal of Mycology
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    • v.46 no.2
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    • pp.186-192
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    • 2018
  • Rapid and accurate detection methods for Colletotrichum coccodes, an anthracnose pathogen of pepper and tomato, were developed using PCR. A specific primer set, coccoTef-F/coccoTef-R, which was constructed by analyzing tef-$1{\alpha}$ genes from 13 species and 22 strains of Colletotrichum, could specifically detect C. coccodes at a level of 10 ng by conventional PCR method and at 10 pg by real-time PCR. The PCR-based methods were also capable of detecting C. coccodes in pepper and tomato seeds artificially infected with the pathogen. The developed PCR methods can be applied for rapid and accurate inspection of C. coccodes in the seeds intended for export or import.

Factors influencing Cognitive Function in Women Cancer Patients Receiving Chemotherapy (항암화학요법을 받는 여성암 환자의 인지기능에 영향을 미치는 요인)

  • Jun, Eun-Young
    • Journal of Haehwa Medicine
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    • v.23 no.2
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    • pp.23-32
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    • 2015
  • Objective : The purpose of this study was to examine the level of the cognitive function, and to identify the influencing factors on cognitive function in women cancer patients receiving chemotherapy. This study attempted to provide basic data useful to development of nursing intervention and improve the quality of life in women cancer patients. Methods : As a cross-sectional descriptive study, women with receiving chemotherapy above one cycle were recruited. One hundred and twenty-five women cancer patients who met the study criteria agreed to participate in the study. The questionnaire set consisted of cognitive function, quality of life, depression, anxiety and information on demographic and clinical characteristics. Results : There was no statistically significant difference in clinical characteristics according to the cognitive function. The cognitive function was higher the more low age (F=9.937, p<.001), and the more high education level (F=12.332, p<.001). Multiple regression analysis showed the predictors were significantly related to cognitive function. age, education, and the number of chemotherapy explained 31.8% of the cognitive function. Conclusions : This result of this study provides basic information about factors influencing cognitive function, although study findings are insufficient in explaining related variables among women cancer patients. Even though women cancer patients were receiving chemotherapy, this study showed that the level of cognitive function was high. In order to receive better results and findings the period decreasing cognitive function, further studies are need to measure cognitive function according to the passage of time during or after chemotherapy.

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