• Title/Summary/Keyword: Level 3 PSA

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3D Reconstruction Using Segmentation of Myocardial SPECT (SPECT 심근영상의 영상분할을 이용한 3차원 재구성)

  • Jung, Jae-Eun;Lee, Jun-Haeng;Choi, Seok-Yoon;Lee, Sang-Bock
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.6
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    • pp.2240-2245
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    • 2010
  • Myocardial imaging in SPECT (Single Photon Emission Computed tomography) scan of the gamma-ray emitting radiopharmaceuticals to patients after intravenous radiopharmaceuticals evenly spread in the heart region of interest by recording changes in the disease caused by a computer using the PSA test is to diagnose. Containing information on the functional myocardial perfusion imaging is a useful way to examine non-invasive heart disease, but the argument by noise and low resolution of the physical landscape that is difficult to give. For this paper, the level of myocardial imaging by using the three algorithms to split the video into 3-D implementation of the partitioned area to help you read the proposed plan. To solve the difficulty of reading level, interest in using the sheet set, partitioned area of the left ventricle was ranked the partitioned area was modeled as a 3-D images.

On the Cultural Characteristics and Wood-Decayedness of Wood-Decaying Fungi in Korea (목재부후균의 배양적 특성과 부후성에 관한 연구)

  • 윤정구;홍순우;백수봉
    • Korean Journal of Microbiology
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    • v.19 no.3
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    • pp.128-136
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    • 1981
  • In order to investigate early identification of species of the wood-decaying fungi in the the mycelial stage, the authors isolated of 41 species, 28 genus, 9 family at 8 locations in Korea and cultivated these isolates on the various kinds of solid media. After investigating such cultural characteristics as oxidase reactions with tannic and gallic acid, various morphological features of colony and growth grade, appeared on the various media, the authors obtained the following results : 1. The oxidase reactions with tannic and gallic acid in the PDTA, DTA, PDGA and DGA media are available for identificantion of the wood-decaying fungi. 2. The oxidase reactions with guaiacol, pyrogallol and hydroquinone in the PDGUA, PDPA and PDHA media are not so much available for identification of the wood-decaying fungi. 3. Morphological features of colonies such as mycelium color, floccose, floccose-powdery, mycelloid, powdery-mycelloid, velvet, radiate, contoured, rosulate and growth grade on the PDA, PSA and PXA media are useful for identification of wood-decaying fungi. 4. It is believed that early identification in species level of wood-decaying fungi using cultural characteristics in the mycelial stage is possible. 5. The key for the identification of 41 species of wood-decaying fungi is proposed by the cultural characteristics using several solid media.

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UNCERTAINTY AND SENSITIVITY STUDIES WITH THE PROBABILISTIC ACCIDENT CONSEQUENCE ASSESSMENT CODE OSCAAR

  • HOMMA TOSHIMITSU;TOMITA KENICHI;HATO SHINJI
    • Nuclear Engineering and Technology
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    • v.37 no.3
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    • pp.245-258
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    • 2005
  • This paper addresses two types of uncertainty: stochastic uncertainty and subjective uncertainty in probabilistic accident consequence assessments. The off-site consequence assessment code OSCAAR has been applied to uncertainty and sensitivity analyses on the individual risks of early fatality and latent cancer fatality in the population outside the plant boundary due to a severe accident. A new stratified meteorological sampling scheme was successfully implemented into the trajectory model for atmospheric dispersion and the statistical variability of the probability distributions of the consequence was examined. A total of 65 uncertain input parameters was considered and 128 runs of OSCAAR with 144 meteorological sequences were performed in the parameter uncertainty analysis. The study provided the range of uncertainty for the expected values of individual risks of early and latent cancer fatality close to the site. In the sensitivity analyses, the correlation/regression measures were useful for identifying those input parameters whose uncertainty makes an important contribution to the overall uncertainty for the consequence. This could provide valuable insights into areas for further research aiming at reducing the uncertainties.

Association between Nutrient Intakes and Benign Prostate Hyperplasia (영양소 섭취와 전립선비대증과의 연관성 연구)

  • Park Hyesook;Chang Namsoo;Kim Eunjung;Yun Hana;Lee Hunjae;Lee BoEun;Kim HanHae;Kwon Sungwon;Seong Yu Jin
    • Journal of Nutrition and Health
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    • v.37 no.9
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    • pp.801-808
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    • 2004
  • Benign prostatic hyperplasia (BPH) is the most common prostate disease in middle aged and elderly men. Therefore, identifying risk factors for BPH is crucial for understanding the etiology and for undertaking interventions or targeting strategies. The survey was carried out in two steps: first, pilot study was conducted prior to the main study in order to estimate baseline characteristics. Second, main study investigated prevalence and risk factors of BPH by clinical diagnostic tests and questionnaire. A total of 641 male aged 50-79 years participated in this community-based cross-sectional study. Using 24 hour recall of food consumption, we found that animal fat intakes increased the risk of BPH with adjusted for age, chronic bronchitis, PSA level, drinking frequency, and excercise frequency (odds ratio 1.84,95% confidence interval 1.10-3.06) . Although BPH has been considered as unavoidable disease with advancing age, if these dietary risk factors are clearly identified, it can be prevented effectively by laying special emphasis on those at risk.

Removal Efficiency of Microstickies by Flotation Process (부유부상 공정의 마이크로 스틱키 제거 효율에 관한 연구)

  • Park, Il;Lee, Hak-Lae
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.37 no.3
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    • pp.1-8
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    • 2005
  • Increase in the utilization rate of recycled paper and closing level of papermaking system increased the problem associated with stickies that include decrease in process runnability and product quality. It is required to establish a process for removing the micro stickies to solve the problems associated with stickies. In this study, the application of flotation process as a method to remove micro stickies was examined. Model micro stickies (MMS) were prepared using microcrystalline cellulose (MCC) and pressure sensitive adhesives (PSA), and the influence of three nonionic surfactants on the removal efficiency of MMS from flotation process was examined. Also the effect of surfactants on the deposition of micro stickies that remaining in the papermaking wet end onto wire was examined. Removal efficiency of MMS by flotation was increased when the proportion of nonionic surfactant with propylene oxide (PO) type hydrophilic tail was increased and stock pH was 7. It was suggested that this nonionic surfactant minimized the increase of surface energy of hydrophobic MMS. The MMS with high hydrophobicity remaining in the papermaking system, however, would cause more serious deposition problems on papermaking wet end. Therefore, it is of great importance to increase the removal efficiency of MMS in flotation process for the prevention of papermaking system contamination caused by stickies deposition.

Implicit Treatment of Technical Specification and Thermal Hydraulic Parameter Uncertainties in Gaussian Process Model to Estimate Safety Margin

  • Fynan, Douglas A.;Ahn, Kwang-Il
    • Nuclear Engineering and Technology
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    • v.48 no.3
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    • pp.684-701
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    • 2016
  • The Gaussian process model (GPM) is a flexible surrogate model that can be used for nonparametric regression for multivariate problems. A unique feature of the GPM is that a prediction variance is automatically provided with the regression function. In this paper, we estimate the safety margin of a nuclear power plant by performing regression on the output of best-estimate simulations of a large-break loss-of-coolant accident with sampling of safety system configuration, sequence timing, technical specifications, and thermal hydraulic parameter uncertainties. The key aspect of our approach is that the GPM regression is only performed on the dominant input variables, the safety injection flow rate and the delay time for AC powered pumps to start representing sequence timing uncertainty, providing a predictive model for the peak clad temperature during a reflood phase. Other uncertainties are interpreted as contributors to the measurement noise of the code output and are implicitly treated in the GPM in the noise variance term, providing local uncertainty bounds for the peak clad temperature. We discuss the applicability of the foregoing method to reduce the use of conservative assumptions in best estimate plus uncertainty (BEPU) and Level 1 probabilistic safety assessment (PSA) success criteria definitions while dealing with a large number of uncertainties.

Risk Assessment of Integrated Leak Rate Test(ILRT) Extension for Korea Standard Nuclear Power Plant (한국표준형원전의 격납건물종합누설률 시험 주기연장에 대한 리스크 평가)

  • Chi, Moon-Goo;Hwang, Seok-Won;Oh, Ji-Yong
    • Journal of the Korean Society of Safety
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    • v.26 no.5
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    • pp.99-104
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    • 2011
  • An ILRT Interval for a nuclear power plant in Korea was extended from once in five years to once in ten years. Therefore, it is necessary to evaluate risk impact for ILRT interval extensions. In this paper, input data were generated for the reference plants, KSNP, using raw data such as meteorological data, population distribution data and source term data. And, using MACCS II code the risk impact assessment was performed based on the two methodologies of NUREG-1493 and NEI Interim Report. The risk impact derived from an ILRT interval extension was identified not to be significant. It is considered to apply this study and results to making an accident management plan and safety goal, and to the field of public acceptance.

Molecular Cloning and Characterization of a cDNA for the PSI-H Subunit Homolog of Photosystem I in Chinese Cabbage (배추로부터 광계 I의 PSI-H Subunit Homolog의 클로닝 및 분자생물학적 특성 연구)

  • Cha, Joon-Yung;Choi, Young-Jin;Lee, Hyo-Shin;Kim, Ki-Yong;Park, Geun-Je;Jo, Jin-Ki;Son, Dae-Young
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.22 no.1
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    • pp.51-58
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    • 2002
  • PSI-H is an intrinsic membrane protein known to be essential for efficient electron flow in PSI complex. We isolated a cDNA clone encoding a PSI-H subunit homolog from Chinese cabbage (Brassica campestris L.). The cDNA, designated bpsaH, had an insert of 435 bp and a full open reading frame that would encode a protein of 145 amino acids. The amino acid sequence deduced from the cDNA sequence is 79.3% identical to that of spinach, suggesting the cDNA most likely encodes Chinese cabbage PSI-H subunit. The bpasH was expressed at high level in leaf tissue and low level in flower bud, whereas it was undetectable in root tissue.

CDC6 mRNA Expression Is Associated with the Aggressiveness of Prostate Cancer

  • Kim, Ye-Hwan;Byun, Young Joon;Kim, Won Tae;Jeong, Pildu;Yan, Chunri;Kang, Ho Won;Kim, Yong-June;Lee, Sang-Cheol;Moon, Sung-Kwon;Choi, Yung-Hyun;Yun, Seok Joong;Kim, Wun-Jae
    • Journal of Korean Medical Science
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    • v.33 no.47
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    • pp.303.1-303.10
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    • 2018
  • Background: Cell division cycle 6 (CDC6) is an essential regulator of DNA replication and plays important roles in the activation and maintenance of the checkpoint mechanisms in the cell cycle. CDC6 has been associated with oncogenic activities in human cancers; however, the clinical significance of CDC6 in prostate cancer (PCa) remains unclear. Therefore, we investigated whether the CDC6 mRNA expression level is a diagnostic and prognostic marker in PCa. Methods: The study subjects included 121 PCa patients and 66 age-matched benign prostatic hyperplasia (BPH) patients. CDC6 expression was evaluated using real-time polymerase chain reaction and immunohistochemical (IH) staining, and then compared according to the clinicopathological characteristics of PCa. Results: CDC6 mRNA expression was significantly higher in PCa tissues than in BPH control tissues (P = 0.005). In addition, CDC6 expression was significantly higher in patients with elevated prostate-specific antigen (PSA) levels (> 20 ng/mL), a high Gleason score, and advanced stage than in those with low PSA levels, a low Gleason score, and earlier stage, respectively. Multivariate logistic regression analysis showed that high expression of CDC6 was significantly associated with advanced stage (${\geq}T3b$) (odds ratio [OR], 3.005; confidence interval [CI], 1.212-7.450; P = 0.018) and metastasis (OR, 4.192; CI, 1.079-16.286; P = 0.038). Intense IH staining for CDC6 was significantly associated with a high Gleason score and advanced tumor stage including lymph node metastasis stage (linear-by-linear association, P = 0.044 and P = 0.003, respectively). Conclusion: CDC6 expression is associated with aggressive clinicopathological characteristics in PCa. CDC6 may be a potential diagnostic and prognostic marker in PCa patients.

Synthesis of Polymeric Surfactants Using CSTR and Their Emulsion PSA Properties (연속 교반 반응기를 이용한 고분자 유화제 합성 및 에멀션 점착 물성)

  • Seung-Min Lim;Myung-Cheon Lee
    • Journal of Adhesion and Interface
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    • v.24 no.3
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    • pp.77-85
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    • 2023
  • In this research, polymeric anionic surfactants having various molecular weights and acid values were synthesized using a continuous stirred tank reactor (CSTR). The CSTR has an advantage of higher production rate and more constant product properties compared to batch and semi-batch reactors. The polymeric surfactants were made using butyl acrylate as a hydrophobic group and acrylic acid as a hydrophilic group. The synthesized polymeric surfactants were ionized with alkali solution and were used as an anionic surfactant. To investigate the properties as a surfactant, the properties of the synthesized surfactant, such as acid value, critical micelle concentration (CMC) and molecular weight, were measured. The results showed that the acid values of the polymeric surfactants were 60 to 380 and a number average molecular weight were 8,000 to 13,000 g/mol. Also, it was found that the CMC was around 0.01 g/ml, which showed similar level values with ordinary surfactant. To prove the performance of the polymeric surfactant, acrylic emulsion PSAs were synthesized using the acquired polymeric surfactant. The results showed that the maximum peel strength of 21.24 N/25mm when acid value was 150 and molecular weight was 8,500 g/mol. The values of peel strength and initial tack of acrylic emulsion PSAs using polymeric surfactant synthesized in this study showed much higher than those of reference PSAs synthesized using ordinary anionic surfactant, SDS (Sodium Dodecyl Sulfate) and SDS/TRX (Triton X-100).