• 정신신체의학
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• 제4권1호
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• pp.71-78
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• 1996

The objective of this study is to evaluate the relationship of hopelessness and suicidal lethality of suicide attempters. The subjects were 72 persons who attempted suicide and came to the emergency room of Chungbuk National University Hospital from April 1st, 1995 to March 31st, 1996. The hopelessness of suicide attempter was assessed by Beck Hopelessness Scale(BHS), and the suicidal lethality was assessed by Risk-Rescue score. The Risk-Rescue Scores exhibited no significant differences in demographic characteristics (sex, age, education, religion, marital status, socioeconomic class, occupation) and psychiatric diagnoses. But the Risk-Rescue scores were significantly higher in high BHS group(BHS score ${\geq}$ 9) than in low BHS group(BHS score <9) and positive correlation was observed between the BHS and the Risk-Rescue score(Rs=0.77 : p<0.05). These results suggest that level of hopelessness be a major risk factor for suicidal lethality.

• 미생물학회지
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• 제25권3호
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• pp.249-253
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• 1987

Effects of Ac pulse at low voltage on Saccharomyces cerevisiae were studied. The treatment of yeast suspensions contained 0.2m NaCl with 500mA for 350 sec at $40^{\circ}C$ was shown about 50% of lethality, whereas in the treatment of the same suspensions with 250mA for 250 sec at the temperature ($10^{\circ}C$) corresponding to about 10% of lethality, growth was completely inhibited instead of lethality. The effect of growth inhibition was due to occurrence of auxotrophic strains under experimental conditions. Detection of auxotrophic yeasts was done tentatively with the difference of the number of viable yeast cells between direct counting by methylene blue staining and plate-count on yeast morphology agar.

• 한국항공우주학회지
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• 제38권3호
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• pp.288-293
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• 2010

본 논문은 장 단거리 공대공 미사일의 치사율을 계산하고, 대상 미사일의 모델을 구성하여 모의 발사 시험 프로그램을 개발하고자 한다. 신뢰성 있는 치사율을 계산하기 위해서는 신관과 탄두에 대한 많은 자료와 실험이 필요하지만 현실적으로 그런 작업을 수행 하기엔 한계가 있다. 따라서 본 논문에서는 참고문헌[3-6]에서 획득한 치사율에 대한 자료를 분석하여 치사율을 계산하였다. 모의시험을 위한 시뮬레이션 프로그램은 MATLAB/SIMULINK를 이용하여 6 DOF 시뮬레이션 모델을 구성하였으며, 수직, 수평 가속도 피드백을 이용한 자동비행 알고리즘과 PNG(Proportional Navigation Guidance)을 이용한 유도명령 알고리즘, 그리고 시간지연과 오차를 고려한 탐색기(seeker)의 동적 모델을 구성하여 적용하였다. 최종적으로 정면발사, 측면발사, 후면발사의 3가지 경우에 대하여 모의 비행을 수행하여 결과를 정리하였으며, 이때 목표물은 일정한 방향을 가지고 등속비행을 하는 것으로 설계하였다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제32권1호
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• pp.17-27
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• 2021

Objectives: Deliberate self-poisoning (DSP) is the most common suicide method and can be life-threatening. The purpose of this study was to investigate the factors related to the lethality of DSP and the characteristics of the adolescent group. Methods: A retrospective study was conducted on patients who had visited an academic hospital's regional emergency medical center between 2015 and 2018. The data reviewed through their medical records included sociodemographic factors, clinical variables, and psychiatric treatment. Four groups (Q1-Q4) were categorized by descriptive analysis using the risk-rescue rating scale. Results: A total of 491 patients were enrolled in this study. This study showed that high lethality had statistically significant associations with male sex, older age, admitting suicidal intentions, and the use of herbicides for suicide. Logistic regression analyses showed a significant association between high-lethality and female [odds ratio (OR)=0.50, 95% confidence interval (CI)=0.30-0.81, p=0.01], non-psychiatric drugs (over-the-counter drug: OR=2.49, 95% CI=1.08-5.74, p=0.03; herbicide: OR=8.65, 95% CI=3.91-19.13, p<0.01), and denial of suicide intent (OR=0.28, 95% CI=0.15-0.55, p<0.01). Conclusion: This study showed the clinical factors associated with the high lethality of DSP and suggested that efforts were needed to care for and thoroughly examine patients with DSP.

• 한국식품영양과학회지
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• 제30권2호
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• pp.222-227
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• 2001

The members of the genus Vibrio include harmless aquatic strain as well as strains capable of causing infections in human and fish. Pathogenic mechanisms are only understood for Vibrio cholerae O1 and O139 and not for the majority of Vibrio species. Twelve clinical and nonclinical strains were examined by in vitro and in vivo experiments for the importance of extracellular enzymes as a virulence determinant of Vibrio species. In vivo cytotoxicity assay was performed by injecting approximately $10^{8}$ cells/mL into mice (BALB/c). V. harvyi and V. vulnificus showed 100% lethality within 3hr after bacterial injection. V. fluvialis and four strains of V. parahaemolyticus showed 50% lethality within 4hr. V. mimicus, V. alginolyticus and V. furnissii revealed 30% lethality within 9hr. Nonclinical strains, V. campbellii and V. ordalii, did not show any lethality. In vitro protease and hemolytic activities were also good indicators for clinical and nonclinical strains of Vibrio species. The clinical strains showed much higher activities than nonclinical strains. The activity of some clinical strains of re-isolates was evidently increased. Most clinical strains had $\beta$ hemolytic activity. The results demonstrate that the prevalent distribution of extracellular proteases in pathogenic Vibrio sp. implies their importance as a virulence determinant.

• Strategy21
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• 통권44호
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• pp.79-102
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• 2018

2015년 미 해군에서 발간한 미 수상함대전략(Surface Force Strategy)에 따르면, 미 해군은 반접근-지역거부(Anti-Acess and Anti-Denial, A2/AD) 전략에 대한 대응책으로 '분산된 치명성(Distributed Lethality, DL)'이라는 신 작전개념을 개발 중에 있다. 이 개념은 각 유닛(unit)의 공격력(offensive power)을 향상시키고 지리적으로 분산 시킴으로써(geographical dispersion) 생존성을 향상시키는데 목적을 두고 있다. 하지만 동맹국(한국/일본 등)이 '분산된 치명성(DL)' 개념에 기여할 수 있는 영역이 다양함에도 불구하고, 지금까지 미 해군 내에서는 동맹국과 어떻게 공조해야 할 것인가에 대한 논의가 부족한 것이 사실이다. 따라서, 미 해군은 향후 '분산된 치명성(DL)' 이라는 작전개념에 동맹국이 줄 수 있는 이점을 추가적으로 적용하는 '동맹국을 활용한 분산된 치명성(Distributed Lethality with Allies, DL+A)' 개념을 발전시켜야 할 것이다. '동맹국을 활용한 분산된 치명성(DL+A)' 개념이란 동맹국이 가지고 있는 전력, 시설, 플랫폼 등 가용자산을 최대한 활용하여 기존의 '분산된 치명성(DL)' 개념을 강화시키는 신 작전개념이다. 미 해군은 본 논문에서 제시하는 신 작전개념(DL+A)을 적용함으로써 다양한 영역(정찰, 군수, 지리적 요충지, 플랫폼)에서 동맹국으로부터 지원을 받을 수 있을 것이다. 또한, 동맹국은 미 해군의 신 작전개념을 적용함으로써 A2/AD 전략에 대비한 안보능력을 향상시킬 수 있을 것이다.

• 대한안전경영과학회지
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• 제25권4호
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• pp.117-129
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• 2023

This study tested the effect on the toxicity of formaldehyde to select a shelter site due to formaldehyde leakage. As a result of the experiment, the range of ERPG-2 and 3 is between 2.2km and 9.6km, ASET is 6 minutes at 1km, 15 minutes at 3km, 22 minutes at 5km, and the lethality rate is 99.9% at 1km and 9% at 3km. In areas where refuge time is less than 15 minutes or the lethality rate is more than 2%, a shelter is installed. This is because if there are only a few evacuees, the evacuation time may take longer than the pre-movement time of 15 minutes or less specified in PD 7974-6:2004, and the lethality rate with the lowest number of deaths was calculated to be 2%. The shelter must be equipped with a hepa-filter, positive pressure equipment, air purifier, air respirator, goggles, chemical protective clothing type 4 and sufficient parking space must be secured to ensure the safety of evacuees.

• 대한안전경영과학회지
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• 제26권2호
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• pp.11-22
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• 2024

This study aims to present safety distances by the damage impact assessment of the leakage of propylene oxide. As a result of the experiment, the pressure 1psi range was 52m to 169m, the radiant heat 18kW/m² range was 63m to 163m, the AEGL-2 range was analyzed as 224m to 414m, and the fire ball diameter was analyzed to be 45m to 121m. Additionally, the extent of damages was proportional to the amount of propylene oxide stored or handled. The safe distance for a 10% lethality due to overpressure and radiant heat was calculated to be 134m, and the safe distance for a 0% lethality was 169m. Toxicity was measured at 134m with a lethality 0%. Therefore, the safety distance due to leakage of propylene oxide is calculated to be between 134m and 169m.

• 약학회지
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• 제40권1호
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• pp.84-89
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• 1996

This study was done to investigate the effect of glycyrrhizin on the lethality induced by galactosamine and lipopolysaccharide coadministration in mice. Glycyrrhizin was injecte d intravenously as a multiple dose at 20, 15, 10, 5, and O hr before galactosamine and lipopolysaccharide coadministration. Lethality and tumor necrosis factor (TNF${\alpha}$) level in serum were surveyed as markers of glycyrrhizin effect. Glycyrrhizin had no effect on the lethality induced by galactosamine and lipopolysaccharide when glycyrrhizin was administered as a single dose. Glycyrrhizin reduced the lethality induced by galactosamine and LPS in dose-dependent manner when glycyrrhizin was administered as a multiple dose at 20, 15, 10, 5 and O hr before galactosamine and lipopolysaccharide coadministration. Glycyrrhizin reduced the serum TNF${\alpha$ level.

• 한국시뮬레이션학회논문지
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• 제28권1호
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• pp.109-115
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• 2019

격실 내 인명 살상확률을 계산하는 문제는 무기체계의 효과분석에 있어서 중요한 문제이다. 본 연구에서는 바닥 면이 정사각형인 직육면체 형태의 격실에서 격실 크기에 따른 인명 살상확률 100%를 만족하는 최소 화약량을 산출하는 식을 개발한다. 내부 폭발로 인해 생성된 폭풍파의 압력 이력은 고속 계산 폭압 모델로 계산하였고, 폭풍파에 노출된 인명의 살상확률은 Axelsson SP 방법론을 적용하여 계산하였다. 한 변의 길이가 5m에서 15m인 정사각형을 바닥 면으로 하는 격실 안에서 무게 20kg에서 170kg의 TNT가 폭발하는 총 176 가지의 시나리오들에 대해 시뮬레이션이 수행되었다. 선형 모델 및 화약밀도기반 모델을 개발하여 표적 격실의 바닥 면의 한 변의 길이에 따른 인명피해 100%를 만족하는 최소 폭약량을 예측하였다.