• Journal of Chest Surgery
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• v.12 no.2
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• pp.119-126
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• 1979

This is one case report of the extremely rare congenital cardiac malformation, Double-outlet of left ventricle in corrected transposition of great arteries. 11-year-old boy complained acrocyanosis and exertional dyspnea, the parents noticed cyanosis since birth. Physical examination revealed acrocyanosis, clubbed fingers and toes, G-III pansystolic murmur on 2nd and 3rd ICS, LSB. Right heart catheterization revealed significant $O_2$ jump in ventricular level. Right and left ventriculography showed the both catheters arriving in the same ventricle i.e. anterior chamber, morphological left ventricle was in right and anterior position, simultaneous visualization of aorta and pulmonary artery and aorta locating anterior and right side of pulmonary artery. Echo cardiogram surely disclosed interventricular septum. Conclusively it was clarified that the patient has Double-outlet of left ventricle and corrected transposition of great arteries [S.L.D.]. Operation was performed to correct the anomalies under extracorporeal circulation with intermittent moderate hypothermia. Right-sided ventriculotomy disclosed the following findings. 1. Right-sided ventricle was morphological left ventricle. 2. Left-sided ventricle was morphological right ventricle. 3. Right side atrioventricular valve was bicuspid. 4. Left side atrioventricular valve was tricuspid. 5. Aortic valve was superior, anterior and right side of pulmonary valve. 6. Subpulmonary membranous stenosis. 7. Non-committed ventricular septal defect. We made a tunnel between VSD and aorta with Teflon patch so that arterial blood comes through VSD and the tunnel into aorta. After correction the patient needed assisted circulation for 135 min. to have adequate blood pressure. Postoperatively by any means, adequate blood pressure could not be maintained and expired in the evening of operation day.

• Journal of Biomedical Engineering Research
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• v.23 no.2
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• pp.101-107
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• 2002

This paper presents a segmentation algorithm to extract endocardial contour and epicardial contour of left ventricle in MR Cardiac images. The algorithm is based on a generalized gradient vector flow(GGVF) snake and a prediction of initial contour(PIC). Especially. the proposed algorithm uses physical characteristics of endocardial and epicardial contours, cross profile correlation matching(CPCM), and a mixed interpolation model. In the experiment, the proposed method is applied to short axis MR cardiac image set, which are obtained by Siemens, Medinus, and GE MRI Systems. The experimental results show that the proposed algorithm can extract acceptable epicardial and endocardial walls. We calculate quantitative parameters from the segmented results, which are displayed graphically. The segmented left vents role is visualized volumetrically by surface rendering. The proposed algorithm is implemented on Windows environment using Visual C ++.

• Journal of Veterinary Clinics
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• v.32 no.6
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• pp.486-490
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• 2015

Two-demensional echocardiography is routinely used for evaluation of cardiac function. Visualization of the endocardial border is essential for the assessment of global and regional left ventricular with cardiac disease. SonoVue$^{TM}$ is a microbubble contrast agent that consists of sulfur hexafluoride-filled microbubbles in a phospholipid shell. There were many studies about contrast echocardiographic examination using SonoVue$^{TM}$ contrast agent, and various doses of SonoVue$^{TM}$ were used. To our knowledge, in published veterinary medicine, there was not reported for diagnostic efficient dose of SonoVue$^{TM}$ to evaluate contrast enhanced left ventricular endocardial border delineation (LVEBD). The purpose of this study is to compare the visualization time of LVEBD and find efficient dose of SonoVue$^{TM}$ for using various doses in dogs. Ten healthy Beagles were recruited to the study. Three different doses (0.03 ml/kg, 0.05 ml/kg and 0.1 ml/kg) of SonoVue$^{TM}$ were injected. Endocardial segments were assigned based on previously established methodology, where by the four-chamber views of the LV were divided into 6 segments. In this study, Contrast enhancement of the LVEBD after each injection was evaluated visually at the time point of overall contrast enhancement (Segmental scoring 5+) in the LV by three investigators in a blind manner. Statistical analysis was performed with SPSS version 14.0. All data were analyzed using one-way ANOVA, the multiple comparison Scheffe test. When data for the three offsite readers were combined, mean durations of useful contrast were $3.54({\pm}2.14)$, $6.15({\pm}2.61)$, and $24.39({\pm}11.10)$ seconds for the 0.03 ml/kg, 0.05 ml/kg, and 0.1 ml/kg SonoVue$^{TM}$ doses, respectively. After injection of contrast agent, there were no significant change in side effects such as urticaria, angioedema, hypersensitivity reactions, and digestive system disorders. This study suggests that efficient dose of SonoVue$^{TM}$ contrast agent for improvement of the left ventricle visualization is 0.1 ml/kg. The duration of useful enhancement of LVEBD and the reproducibility were also the highest at the 0.1 ml/kg dosage.

• Korean Journal of Veterinary Research
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• v.55 no.1
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• pp.47-52
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• 2015

The purpose of this study was to determine if contrast media would enhance visualization of the endocardium for assessment of left ventricle (LV) function. In addition, differences between pre- and post-contrast evaluation for the cardiac output measurements including the modified Simpson's method and automated contour tracking (ACT) method were examined. Ten clinically healthy adult beagle dogs (three males and seven females) between 2~3 years old and weighing 6.6~10.8 kg were used. Echocardiographic examinations were performed to compare pre- and post-contrast LV endocardium visualization using a segmental scoring method. Two different methods for measuring cardiac output were also compared. LV visualization was significantly enhanced in post-contrast echocardiography (p < 0.01). Significant differences between pre- and post-contrast measurements for the modified Simpson's method (p < 0.05) were also observed. No significant difference was found for the ACT method. Contrast echocardiography provides better LV chamber opacification and significantly improves wall segment visualization. Furthermore, contrast echocardiography for measuring cardiac output is helpful for the modified Simpson's method.

• Journal of Chest Surgery
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• v.47 no.4
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• pp.434-436
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• 2014

Left ventricular thrombus is a common complication related to acute myocardial infarction. Removing this with an incision of the free wall of the left ventricle may cause fatal cardiac dysfunction or arrhythmias. Furthermore, performing incision and suture on the fragile myocardium of an acute myocardial infarction patient may cause serious bleeding complications. If there is a patient with left ventricular thrombus who needs thoracotomy for another reason, the case is attempted with the thought that if effective intraventricular visualization and manipulation can be done, fatalities caused by incision and suture may be reduced. For patients undergoing cardiopulmonary bypass, if intracardiac manipulation is required, an endoscope can be used, and given the potential complications after the incision and suturing of the infarcted tissue, the benefits are deemed sufficient.

• Journal of KIISE:Computer Systems and Theory
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• v.27 no.7
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• pp.629-638
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• 2000

The main difference between mono-volume rendering and multi-volume rendering is data intermixing. In this paper, we first propose a selective rendering method for fast visualizing specific volume according to the surface level and then present data intermixing method for multiple volumes. The selective rendering method is to generate distance transformed volume using a distance transform to determine the minimum distance to the nearest interesting part and then render it. The data intermixing method for multiple volumes is to combine several volumes using intensity weighted intermixing method, opacity weighted intermixing method, opacity weighted intermixing method with depth information and then render it. We show the results of selective rendering of left ventricle and right ventricle generated from EBCT cardiac images and of data intermixing for combining original volume and left ventricular volume or right ventricular volume. Our method offers a visualization technique of specific volume according to the surface level and an acceleration technique using a distance transformed volume and the effective visual output and relation of multiple images using three different intermixing methods in three-dimensional space.

• Journal of KIISE:Computer Systems and Theory
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• v.27 no.9
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• pp.768-776
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• 2000

본 논문에서는 심혈관 조영영상으로부터 좌심실의 형태 및 운동을 가시화하기 위해 기하학적 정보와 물리적 정보를 통합한 동적 가우시안 블럽(dynamic gaussian blob)모델을 개발하였다. 동적 가우시안 블럽 모델은 superellipsoid에 3차원 가우시안 형태함수를 갖는 단일 유한요소를 통합한 것으로, 좌심실에 작용되는 가상적인 힘에 의해 형태를 적하하고, 심박동 전 주기에서의 운동을 추적한다. 또한 벽 운동 정도에 따라 다른 색을 지정하여 볼 수 있도록 함으로써 벽 운동에 이상이 있는 부위를 육안으로 쉽게 판별할 수 있도록 하였다. 이와 같은 좌심실의 동적.색체 가시화는 형태가 변황되는 심장질환이나 허혈이나 심근경색증처럼 심실벽 운동에 이상이 있는 질환의 진단을 도울 수 있다.

• Proceedings of the Korean Information Science Society Conference
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• 2000.04b
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• pp.670-672
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• 2000

본 논문에서는 단일광자방출 전산화단층촬영영상 (SPECT)을 이용하여 좌심실의 내.외벽의 운동을 분리하여 추적하는 방법을 제시한다. 좌심실의 운동은 크게 평행이동, 회전이동, 비강체 변형으로 나뉘어 분석된다. 운동 추적을 위해 사용된 역동적 변형 솔리드는 물체중심 변동 좌표계로써 특징점들의 모드형태벡터를 사용하고, 좌심실 역동성을 유한요소방법에 의해 시뮬레이션한다. 또한, 변형 모델에 대해 묵시적으로 표준화된 parameterization을 하지 않고, 의료영상으로부터 얻은 자료값을 직접 이용하기 위해 노드간 보간함수로써 3차원 가우시안 함수를 사용한다. 그리하여 보다 자연스러운 방식으로 연속적으로 변화하는 좌심실의 운동을 추적할 수 있다. 이러한 분리된 내.외벽 운동 분석은 운동 기능에 이상이 있는 심질환 분석을 보다 효과적으로 도울 수 있다.

• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.1
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• pp.62-69
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• 2012

Purpose: The present study has an objective of effectively separating and making observations on a portion of radiopharmaceutical excreted via digestive organ to remain in the organ and invade a heart shadow. Materials and methods: When heart shadow is blocked by the organ in tests during a resting phase and a loaded phase, additional images were obtained using immobilization device. The immobilization devices were used to tilt the upper body forward from supine position. Results: In the reconstructed image for the separated case, as compared with the case where a part of organ is overlapped with heart, in terms of an overall mean value for each parameter, the end-diastolic volume increased by 2.75 mL, the end-systolic volume decreased by 3.16 mL, the left ventricle cardiac coefficient increased by 3.58%, and the area of defect region decreased by 3.58 and 3.92 cm for loading and resting phase, respectively. Conclusions: In the present study with myocardial perfusion SPECT, overlapped areas of heart and other organs could be effectively separated and visualization by the use of an immobilization device.