• Journal of the Korean Wood Science and Technology
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• 제31권1호
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• pp.16-21
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• 2003

느릅나무 근피의 메탄올 추출물을 분획하여 항균성을 측정한 결과 항균력이 가장 우수한 수용성 분획을 silicagel column chromatograpy 및 TLC에 의해 분리·정제한 다음 정제 화합물을 UV, IR, ¹H-NMR, ¹³C-NMR를 사용하여 구조를 동정하고 그 화합물의 항균력을 검정하였다. 수용성 분획물로부터 두 종류의 정제 화합물을 단리하였다. 기기분석 결과, 화합물 B는 Catechin rhamnoside로 확인되었다. 단리된 정제화합물은 Staphylococcus aureus 및 Salmonella typhimurium에 대하여 항균활성을 나타내었다.

• Journal of Species Research
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• 제12권1호
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• pp.68-89
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• 2023

This is the second catalog listing unrecorded invertebrates discovered during the research project 'Discovery of Korean Indigenous Species'. The data to compile the catalog were primarily gathered from the final reports of the project, between 2013 and 2021. We present 38 previously undocumented species, belonging to four phyla (Platyhelminthes, Annelida, Rotifera and Arthropoda). Samples were collected from intertidal coastal waters, soil, freshwater ponds, reservoirs and hosts in South Korea. In this study, we provide brief taxonomic information, including collection site (GPS), diagnosis, specimen vouchers, figures of representative individuals and the Korean name newly assigned, for each species. All data were reviewed and updated by experts working on the respective taxonomic group. The aim of the present study is to publish species that have been previously reported through the project. Upon publication, these species will be added to the 'National Species List of Korea', curated by the National Institute of Biological Resources(NIBR).

• 한국축산식품학회지
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• 제43권4호
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• pp.612-624
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• 2023

The gut-brain axis encompasses a bidirectional communication pathway between the gastrointestinal microbiota and the central nervous system. There is some evidence to suggest that probiotics may have a positive effect on cognitive function, but more research is needed before any definitive conclusions can be drawn. Inflammation-induced by lipopolysaccharide (LPS) may affect cognitive function. To confirm the effect of probiotics on oxidative stress induced by LPS, the relative expression of antioxidant factors was confirmed, and it was revealed that the administration of probiotics had a positive effect on the expression of antioxidant-related factors. After oral administration of probiotics to mice, an intentional inflammatory response was induced through LPS i.p., and the effect on cognition was confirmed by the Morris water maze test, nitric oxide (NO) assay, and interleukin (IL)-1β enzyme-linked immunosorbent assay performed. Experimental results, levels of NO and IL-1β in the blood of LPS i.p. mice were significantly decreased, and cognitive evaluation using the Morris water maze test showed significant values in the latency and target quadrant percentages in the group that received probiotics. This proves that intake of these probiotics improves cognitive impairment and memory loss through anti-inflammatory and antioxidant mechanisms.

• 대한물리치료과학회지
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• 제25권1호
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• pp.11-19
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• 2018

Purpose : The purpose of this study was to examine the effects of ankle kinesio taping on postural control function during exercise in university students. Method : Thirty subjects were randomly allocated to three groups: Y taping group (n=20), I taping group (n=20) and Non-taping group (n=20). All groups underwent the same exercise program including stretching for 30 minutes. The exercise program proceeded in the following order: five minutes of stretching, a 20-minutes exercise program, and additional five 5 minutes of stretching. Of the eight exercise methods suggested by Purcell et al, seven were chosen (lateral shuffle, forward & backward running, agility ladder, figure-of-8, forward jogging while jumping over cones, wall jumps and zigzags); $90^{\circ}$ cuts with lateral shuffle were omitted. The postural control functions was measured participants's perceptions of stability, confidence, and reassurance using methods suggested by Purcell et al,. Result : The confidence was significant difference in I taping group compared to Non taping group. The reassurance was significant difference in Y taping group and I taping group compared to Non taping group. Conclusion : The Kinesio taping increased confidence, and reassurance during exercise in university students. Additional research on Kinesio taping for improving range of motion and agility is need.

• Journal of Ginseng Research
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• 제42권1호
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• pp.75-80
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• 2018

Background: The aim of the present study was to evaluate the potential protective effects of six ginsenosides (Rb1, Rb2, Rc, Rd, Rg1, and Rg3) isolated from Panax ginseng against tacrolimus (FK506)-induced apoptosis in renal proximal tubular LLC-PK1 cells. Methods: LLC-PK1 cells were treated with FK506 and ginsenosides, and cell viability was measured. Protein expressions of mitogen-activated protein kinases, caspase-3, and kidney injury molecule-1 (KIM-1) were evaluated by Western blotting analyses. The number of apoptotic cells was measured using an image-based cytometric assay. Results: Reduction in cell viability by $60{\mu}M$ FK506 was ameliorated significantly by cotreatment with ginsenosides Rg1 and Rb1. The phosphorylation of p38, extracellular signal-regulated kinases, and KIM-1, and cleavage of caspase-3, increased markedly in LLC-PK1 cells treated with FK506 and significantly decreased after cotreatment with ginsenoside Rb1. The number of apoptotic cells decreased by 6.0% after cotreatment with ginsenoside Rb1 ($10{\mu}M$ and $50{\mu}M$). Conclusion: The antiapoptotic effects of ginsenoside Rb1 on FK506-induced apoptosis were mediated by the inhibition of mitogen-activated protein kinases and caspase activation.

• Tuberculosis and Respiratory Diseases
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• 제78권4호
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• pp.419-422
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• 2015

We presented a case of unusual endobronchial inflammatory polyps as a complication following endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in a patient with tuberculous lymphadenitis. EBUSTBNA of the right hilar lymph node was performed in a 29-year-old, previously healthy man. The patient was confirmed with tuberculous lymphadenitis and received antituberculosis medication over the course of 6 months. Chest computed tomography, after 6 months of antituberculosis therapy following the EBUS-TBNA showed nodular bronchial wall thickening of the right main bronchus. Histological and microbiological examinations revealed inflammatory polyps. After 7 months, the inflammatory polyps regressed almost completely without need for removal.

• Physical Therapy Rehabilitation Science
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• 제3권1호
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• pp.63-68
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• 2014

Objective: The purpose of this study was to examine the effects of ankle Kinesio taping on range of motion and agility during exercise in university students. Design: Cross-sectional study. Methods: Thirty subjects were randomly allocated to two groups: taping group (n=15) and non-taping group (n=15). All groups underwent the same exercise program including stretching for 30 minutes. The exercise program proceeded in the following order: five minutes of stretching, a 20-minutes exercise program, and additional five minutes of stretching. Of the eight exercise methods suggested by Purcell et al, seven were chosen (lateral shuffle, forward and backward running, agility ladder, figure-of-8, forward jogging while jumping over cones, wall jumps and zigzags); $90^{\circ}$ cuts with lateral shuffle were omitted. The range of motion of ankle dorsiflexion and plantarflexion was measured using the goniometer. Agility was measured using the side hop test. Results: For ankle range of motion, the taping group showed significant differences in dorsiflexion and plantarflexion on both sides (p<0.05). The non-taping group showed significant differences only in left plantarflexion (p<0.05). There was a significant difference in dorsiflexion on both sides between the taping group and the non-taping group (p<0.05). All groups showed significant differences in agility on the left and right ankle (p<0.05). There was a significant difference in left ankles between the taping group and the non-taping group (p<0.05). Conclusions: Kinesio taping increased range of motion and agility during exercise in university students. Additional research on Kinesio taping for improving range of motion and agility is needed.

• ALGAE
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• 제29권1호
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• pp.47-55
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• 2014

To develop effective and safe acne vulgaris therapies with a continuing demand for new solutions, we investigated unique efficacy of an antibacterial agent from marine brown alga Eisenia bicyclis in treating acne vulgaris. The methanolic extract of E. bicyclis exhibited potential antibacterial activity against acne-related bacteria. The ethyl acetate fraction showed the strongest antibacterial activity against the bacteria among solvent fractions. Six compounds (1-6), previously isolated from the ethyl acetate fraction of E. bicyclis, were evaluated for antibacterial activity against acne-related bacteria. Among them, compound 2 (fucofuroeckol-A [FF]) exhibited the highest antibacterial activity against acne-related bacteria with a minimum inhibitory concentration (MIC) ranging from 32 to $128{\mu}g\;mL^{-1}$. Furthermore, FF clearly reversed the high-level erythromycin and lincomycin resistance of Propionibacterium acnes. The MIC values of erythromycin against P. acnes were dramatically reduced from 2,048 to $1.0{\mu}g\;mL^{-1}$ in combination with MIC of FF ($64{\mu}g\;mL^{-1}$). The fractional inhibitory concentration indices of erythromycin and lincomycin were measured from 0.500 to 0.751 in combination with 32 or $64{\mu}g\;mL^{-1}$ of FF against all tested P. acnes strains, suggesting that FF-erythromycin and FF-lincomycin combinations exert a weak synergistic effect against P. acnes. The results of this study suggest that the compounds derived from E. bicyclis can be a potential source of natural antibacterial agents and a pharmaceutical component against acnerelated bacteria.

• 융합보안논문지
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• 제12권1호
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• pp.63-70
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• 2012

오늘날 스마트폰 시장이 폭발적으로 성장함에 따라 일반인과 시각 장애인의 스마트폰 사용에 차이가 발생하여 정보 활용 격차가 날로 심화되고 있다. 본 논문에서는 시각 장애인의 일반인과의 정보 활용 격차를 줄이기 위해 시각 장애인만을 대상으로 한 저렴한 가격의 요철 필름을 사용한 점자를 기반으로 문자 및 숫자 입력 시스템을 제안한다. 제안된 시스템은 점자의 모양을 기반으로 애플의 iOS 상에 요철 필름과 레이아웃을 설계하여 그 레이아웃에 따라 점자 및 숫자 키보드를 설계하였고, 부가적으로 전화, 문자, 단축 다이얼, 응급 구조를 위한 위치전송 기능을 설계하였다. 점자 키보드를 이용하여 입력한 문자는 자동으로 클립보드로 복사되며 다른 응용에서도 이용할 수 있게 하여 시각 장애인이 스마트폰을 편리하게 사용할 수 있도록 구현 하였다.

• 국제물리치료학회지
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• 제4권2호
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• pp.618-624
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• 2013

The purpose of this study was to test the effect of Gastrocnemius and Low Back-muscle isotonic exercise on static dynamic standing balance during the period of 4 weeks. This study was two groups pretest-posttest design. Nineteen subjects who were over 22 years old were randomly assigned to either the experimental group that received the Gastrocnemius muscle exercise(n=9) or the low back muscle exercise(n=10) : The former group performed isotonic exercise(plantar flexion), the latter group performed isotonic exercise(trunk extension) a total of 18 times for three times per week for four weeks. Two groups also performed static and dynamic balance before the exercise and 4weeks after the exercise. The data were analyzed by using the paired t-test and independent t-test. The results were as follows: As compared with change of dynamic balance performance capacity at two groups, a significant difference was shown in the test(p<.05), but not in static balance(p>.05). Also, a significant difference of balance between groups was not shown in the test. In this study indicated that gastrocnemius and low back muscle isotonic exercise will have positive impact on standing balance.