• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2021년도 춘계학술대회
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• pp.189-192
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• 2021

항적추적 기술에 딥러닝 기반 LSTM(Long Short-Term Memory) 모델을 적용하는 연구로서 기존의 항적추적기술의 경우, 항공기의 등속, 등가속, 급기동, 선회(3D) 비행 등 비행 특성에 따른 칼만 필터 기반의 LMIPDA를 활용한 실시간 항적 추적 시 등속, 등가속, 급기동, 선회(3D) 비행 가중치가 자동으로 변경된다. 이러한 과정에서 등속 비행 중 급기동 비행과 같이 비행 특성이 변경될 때, 항적 손실 및 항적 추적 성능이 하락하여 비행 특성 가중치 변경성능을 향상시킬 필요성이 있다. 본 연구는 레이더의 오차 모델이 적용된 시뮬레이터의 Plot과 표적을 딥러닝 기반 LSTM(Long Short-Term Memory) 모델을 적용하여 학습시키고, 칼만 필터를 활용한 항적추적 결과와 딥러닝 기반 LSTM(Long Short-Term Memory) 모델을 적용한 항적추적결과를 비교함으로써 미리 비행 특성의 변경과정을 예측하여 등속, 등가속, 급기동, 선회(3D) 비행 가중치변경을 신속하게 함으로써 항적추적성능을 향상하기 위한 연구이다.

• 대한한의학회지
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• 제25권4호
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• pp.51-60
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• 2004

Objective : The effect Saenggitang (GT), which has been used for amnesia, in Oriental Medicine, on memory and learning ability, was investigated. Methods : Hot water extracts (HWE) of SGT were used for the studies. In passive avoidance performances (step through test), active avoidance performances (lever press test), Motor activity, pentobarbital-induced sleep, 20 and 50 mg/100g of SGT-HWE ameliorated the memory retrieval deficit induced by 40% ethanol. Results : The SGT-HWE did not affect the ambulatory activity of normal mice in normal condition. 20 and 50 mg/100g of SGT-HWE enhanced contextual fear memory, but not cued fear memory in a fear conditioning task, which requires the activation of the NMDA (N-methyl-D-aspartase) receptor. SGT-HWE did not affect the motor activity measured by the titling type ambulometer test performed immediately and 24 hr after the administration. SGT-HWE prolonged the sleeping time induced by 50 mg/kg pentobarbital in mice and decreased SMA (spontaneous motor activity) in active avoidance performances (lever press test). Conclusion : These results indicate that the SGT-HWE have an improving effect on the memory retrieval disability induced by ethanol and may act as a stimulating factor for activating the NMDA receptor. and the SGT-HWE has a tranquilizing and anti-anxiety action.

• BMB Reports
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• 제41권3호
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• pp.242-247
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• 2008

MSS, a comprising mixture of maesil (Prunus mume Sieb. et Zucc) concentrate, disodium succinate and Span80 (3.6 : 4.6 : 1 ratio) showed a significant improvement of memory when daily administered (460 mg/kg day, p.o.) into the normal rats for 3 weeks. During the spatial learning of 4 days in Morris water maze test, both working memory and short-term working memory index were significantly increased when compared to untreated controls. We investigated a molecular signal transduction mechanism of MSS on the behaviors of spatial learning and memory. MSS treatment increased hippocampal mRNA levels of NR2B and TrkB without changes of NR1, NR2A, ERK1, ERK2 and CREB. However, the protein levels of pERK/ERK and pCREB/CREB were all significantly increased to $1.5{\pm}0.17$ times. These results suggest that the improving effect of spatial memory for MSS is linked to MAPK/ERK signaling pathway that ends up in the phosphorylation of CREB through TrkB and/or NR2B of NMDA receptor.

• 예술인문사회 융합 멀티미디어 논문지
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• 제9권3호
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• pp.747-756
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• 2019

통역을 학습하는 학생들은 수업 외에도 추가적인 학습 및 훈련을 수행한다. 동시통역 및 순차통역에서 두 언어의 구조가 다르기 때문에 통역가는 발표 내용을 빠르게 기억해야 한다. 단기 기억 향상을 위해서 통역을 학습하는 학생들은 메모리 훈련을 수행한다. 메모리 훈련은 파트너가 필요하기 때문에 학습 효율성이 저하되고 자가 학습이 불가능하다. 이를 해결하기 위해서 컴퓨터 기반의 단기 기억 훈련 시스템이 제안되었다. 지문 내 단어를 특수문자로 변경함으로써 학생들이 파트너 없이도 자가 학습이 가능하다. 하지만 컴퓨터는 휴대성이 떨어지기 때문에 외부에서는 학습 능률이 저하된다. 제거되는 단어보다 키워드로 제공하는 단어의 수가 더 많아서 학습 난이도가 저하된다. 이를 해결하기 위해서, 본 논문에서는 스마트 단말 기반의 문장구역 훈련 시스템을 제안하였다. 스마트 단말은 휴대성이 높아 학습의 제한이 없어 효율이 증가한다. 제안하는 훈련 시스템에서는 삭제되는 단어수가 키워드보다 더 많도록 하여 학습 난이도가 증가한다. 제안한 훈련 시스템을 구현하고 기능을 검증하였다.

• PNF and Movement
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• 제6권3호
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• pp.19-28
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• 2008

Purpose : The objective of this study was to determine efficacy of sleep-dependent motor learning. Methods : This is a literature study with books and internet. We searched the PubMed, Science Direct, KISS and DBpia. Key words were Sleep-dependent, motor learning, RAM and LTP. Results : Procedural memory, like declarative memory, undergoes a slow, time-dependent period of consolidation. A process has recently been described wherein performance on some procedural task improves with the mere passage of time and has been termed "enhancement". Some studies have reported that the consolidation/enhancement of perceptual and motor skill is dependent on sleep. Specially, rapid-eye-movement(REM) sleep seems to benefit procedural aspects of memory. Conclusion : Motor learning is very important for CNS injury patients. And also distribution of practice sessions is important because REM sleep is to benefit procedural aspects of memory consolidation.

• 정보학연구
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• 제1권1호
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• pp.65-84
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• 1998

메모리 기반 추론 기법은 분류시 입력 패턴과 저장된 패턴들 사이의 거리를 이용하는 교사 학습 기법으로써, 거리 기반 학습 알고리즘이라고도 한다. 메모리 기반 추론은 k_NN 분류기에 기반한 것으로, 학습은 추가 처리 없이 단순히 학습 패턴들을 메모리에 저장함으로써 수행된다. 본 논문에서는 기존의 k-NN 분류기보다 효율적인 분류가 가능하고, 점진적 학습 기능을 갖는 새로운 알고리즘을 제안한다. 또한 제안된 기법은 노이즈에 민감하지 않으며, 효율적인 메모리 사용을 보장한다.

• 대한한방소아과학회지
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• 제19권1호
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• pp.67-82
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• 2005

Objectives : This study was conducted to find out the effect of Yukmijiwhangtanggamibang (YM) on growth, learning and memory of rats. Methods : It was divided SD rats into Sham group, 192 Saporin injection(SA+Saline) group and Injection of 192 Saporin with YM(SA+YM) group. Growth measure length of bone and tail. Memory performance was used aquisition test and learning retention of morris water maze. It was detected acetylcholinesterase(AChE), cholineacetyltransferase(ChAT) at medial septum and hippocampus by immunohistochemistry Results : Body Weight of the SA+YM Group increased effectively, as compared with SA Saline group. Growth of bone in the SA+YM Group increased effectively, as compared with SA+Saline group. Growth of Tail in the SA+YM Group increased effectively, as compared with SA_Saline group. The SA+YM Group in Aquisition Test improved effectively, as compared with SA+Saline group. The SA+YM Group in Learning Test improved effectively, as compared with SA+Saline group. The numbers of ChAT cells in Medial septum increased effectively, as compared with SA+Saline group. The numbers of ChAT cells in CA1 of Hippocampus increased, but was not effective. Conclusion : These results suggest that YM has an improving effect on the impaired learning through the effects on memory registration and retrieval.

• 한국약용작물학회지
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• 제25권6호
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• pp.353-360
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• 2017

Background: A critical features of Alzheimer's disease (AD) is cognitive dysfunction, which partly arises from decreased in acetylcholine levels. AD afftected brains are characterized by extensive oxidative stress, which is thought to be primarily induced by the amyloid beta ($A{\beta}$) peptide. In a previous study, Cinnamomum loureiroi tincture inhibited acetylcholinesterase (AchE) activity. That study identified AChE inhibitor in the C. loureiroi extract. Furthermore, the C. loureiroi extract enhanced memory in a trimethyltin (TMT)-induced model of cognitive dysfunction, as assessed via two behavioral tests. Rosa laevigata extract protected against oxidative stress-induced cytotoxicity. Administrating R. laevigata extracts to mice significantly reversed $A{\beta}$-induced learning and memory impairment, as shown in behavioral tests. Methods and Results: We conducted behavioral to examine the synergistic effects of C. loureiroi and R. laevigata extracts in inhibiting AChE and counteracting TMT-induced learning and memory losses. We also performed biochemical assays. The biochemical results showed a relationship between increased oxidative stress and cholinergic neurons damage in TMT-treated mice. Conclusions: A diet containing C. loureiroi and R. laevigata extracts ameliorated learning and memory impairments in the Y-maze and passive avoidance tests, and exerted synergistic inhibitory effect against AChE and lipid peroxidation.

• 대한본초학회지
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• 제35권5호
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• pp.33-39
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• 2020

Objectives : Increasing evidence supports the biological and pharmacological activities of essential oils on the central nervous system such as pain, anxiety, attention, arousal, relaxation, sedation and learning and memory. The purpose of present work is to investigate the protective effect and molecular mechanism of cypress essential oil (CEO) against scopolamine (SCO)-induced cognitive impairments in C57BL/6 mice. Methods : A series of behavior tests such as Morris water maze, passive avoidance, and fear conditioning tests were conducted to monitor learning and memory functions. Immunoblotting and RT-PCR were also performed in the hippocampal tissue to determine the underlying mechanism of CEO. Results : SCO induced cognitive impairments as assessed by decreased step-through latency in passive avoidance test, relatively low freezing time in fear conditioning test, and increased time spent to find the hidden platform in Morris water maze test. Conversely, CEO inhalation significantly reversed the SCO-induced cognitive impairments in C57BL/6 mice comparable to control levels. To elucidate the molecular mechanisms of memory enhancing effect of CEO we have examined the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus. CEO effectively elevated the protein as well as mRNA expression of BDNF via activation of cAMP response element binding protein (CREB). Conclusions : Our findings suggest that CEO inhalation effectively restored the SCO-impaired cognitive functions in C56BL/6 mice. This learning and memory enhancing effect of CEO was partly mediated by up-regulation of BDNF via activation of CREB.

• 대한한의학회지
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• 제30권2호
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• pp.1-16
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• 2009

Objectives: This study investigated the effect of Yukmijihwangtang on cerebral ischemia-induced learning and memory impairment by middle cerebral artery (MCA) occlusion in rats. Methods: The ability of learning and memory of rats was measured using the eight-arm radial maze and the passive avoidance test, and profile of cholinergic neuron was assessed in the medial septum and hippocampus region by immuno-histochemistry. Results: 1. No differences were found between groups in the number of correct choices in acquisition performance during the eight-arm radial maze task. 2. No differences were found between groups on day 1 in the error rate in acquisition performance, which is defined as the number of enters into the same arm more than once within five minutes. After 5 to 6 days of test, the number of errors was significantly reduced in the Yukmijihwangtang group (forebrain ischemia group with Yukmijihwangtang treatment), compared with the ischemia group. 3. The memory processes significantly improved in the Yukmijihwangtang group according to results of the passive avoidance test. 4. The appearance of AchE (acetylcholinesterase) in the CA1 region of hippocampus significantly decreased in the ischemia group, compared with the sham group (untreated group). The appearance of AchE in the same region significantly increased in the Yukmijihwangtang group, compared with the ischemia group. 5. The appearance of ChAT (choline acetyltransferase) in the CA1 region of the hippocampus and medial septum decreased in the ischemia group, compared with the sham group. The appearance of ChAT in the same region significantly increased in the Yukmijihwangtang group, compared with the ischemia group Conclusions: This study provides evidence that Yukmijihwangtang is effective for reviving the ability of learning and memory and damaged neurons in rats with experimental cerebral ischemia.