• Title/Summary/Keyword: Leakage reduction

Search Result 485, Processing Time 0.025 seconds

Plant Extracts and Plant-Derived Compounds: Promising Players in Countermeasure Strategy Against Radiological Exposure: A Review

  • Kma, Lakhan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.6
    • /
    • pp.2405-2425
    • /
    • 2014
  • Radiation exposure leads to several pathophysiological conditions, including oxidative damage, inflammation and fibrosis, thereby affecting the survival of organisms. This review explores the radiation countermeasure properties of fourteen (14) plant extracts or plant-derived compounds against these cellular manifestations. It was aimed at evaluating the possible role of plants or its constituents in radiation countermeasure strategy. All the 14 plant extracts or compounds derived from it and considered in this review have shown some radioprotection in different in vivo, ex-vivo and or in vitro models of radiological injury. However, few have demonstrated advantages over the others. C. majus possessing antioxidant, anti-inflammatory and immunomodulatory effects appears to be promising in radioprotection. Its crude extracts as well as various alkaloids and flavonoids derived from it, have shown to enhance survival rate in irradiated mice. Similarly, curcumin with its antioxidant and the ability to ameliorate late effect of radiation exposure, combined with improvement in survival in experimental animal following irradiation, makes it another probable candidate against radiological injury. Furthermore, the extracts of P. hexandrum and P. kurroa in combine treatment regime, M. piperita, E. officinalis, A. sinensis, nutmeg, genistein and ginsan warrants further studies on their radioprotective potentials. However, one that has received a lot of attention is the dietary flaxseed. The scavenging ability against radiation-induced free radicals, prevention of radiation-induced lipid peroxidation, reduction in radiation cachexia, level of inflammatory cytokines and fibrosis, are some of the remarkable characteristics of flaxseed in animal models of radiation injury. While countering the harmful effects of radiation exposure, it has shown its ability to enhance survival rate in experimental animals. Further, flaxseed has been tested and found to be equally effective when administered before or after irradiation, and against low doses (${\leq}5Gy$) to the whole body or high doses (12-13.5 Gy) to the whole thorax. This is particularly relevant since apart from the possibility of using it in pre-conditioning regime in radiotherapy, it could also be used during nuclear plant leakage/accidents and radiological terrorism, which are not pre-determined scenarios. However, considering the infancy of the field of plant-based radioprotectors, all the above-mentioned plant extracts/plant-derived compounds deserves further stringent study in different models of radiation injury.

A Study on the Supply and Stray Current Distribution of the DC Railway Power System (직류전기철도 급전시스템에서 공급 및 누설전류 분포에 관한 연구)

  • Cho, Woong-Ki;Choi, Kyu-Hyoung
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
    • /
    • v.24 no.6
    • /
    • pp.160-168
    • /
    • 2010
  • This paper presents the analysis of the current as stray current and supplied current of the substation, on the DC railway power system. In DC railway power supply system, the running rails are usually used as the return conductor(negative-polarity) for traction load current. This condition mainly focuses on economic considerations, since it does not require the installation of an additional return conductor. But, problems of low resistance between the running rails for the return conductor and earth allows a significant part of the return load current to leak into the earth. This current is normally called to as leakage or stary current. This stary currents creates serious problems for any electrified matter in the underground. Therefore, reduction of stray current of the DC railway power supply system is also of direct benefit to the operational and safety aspects of the DC railway systems. In this paper, deal with the analysis of the current distribution on the DC railway power system applied the common grounding system, using SPLIT of CDEGS program.

The Safety Design of Corrosive Chemical Handling Process based on Reliability Database (신뢰도 데이터베이스 기반 부식성 화학물질 취급공정의 안전설계)

  • Chu, Chang Yeop;Baek, Jong Bae
    • Journal of the Korean Society of Safety
    • /
    • v.33 no.5
    • /
    • pp.141-149
    • /
    • 2018
  • In a PCB factory, there is a corrosive chemical substance supply system that can causes major leakage accidents. These accidents can give rise to shut down the factory and do residents damage that cause enormous loss of properties. To mitigate these risks, it is necessary to provide a chemical disaster prevention system. Moreover, after considering the situation and environment of the production site, it is of great importance to build an optimal chemical accident prevention system by reflecting risk reduction measures from the point of process design and by assessing quantitative risk based on reliability data. However, because there was no established database of the reliability about facilities and equipment that can be used in the domestic, the business site and consulting organization had being used the reliability data such as USA CCPS(Center for Chemical Process Safety). In these days, Korean institutes are studying on reliability data utilization method of quantitative risk assessment for preventing chemical accidents and domestic utilization algorithms and storage bed of reliability data. This study presents samples of reliability database about the chemical substance supply system that constructed from the history data such as failure, maintenance for 10 years at a PCB factory. Also, this work proposes the safety design criteria for supply facilities of corrosive chemical substance by assessing quantitative risk on the basis of the reliability data.

The Study of Optimized Combustion Tuning for Fossil Power Plant (발전보일러의 최적연소조정에 대한 실험적 연구)

  • Jung, Jae-Jin;Song, Jung-Il
    • 한국태양에너지학회:학술대회논문집
    • /
    • 2009.04a
    • /
    • pp.102-108
    • /
    • 2009
  • Fossil power plants firing lower grade coals or equipped with modified system for NOx controls are challenged with maintaining good combustion conditions while maximizing generation and minimizing emissions. In many cases significant derate, availability losses and increase in unburned carbon levels can be attributed to poor combustion conditions as a result of poorly controlled local fuel and air distribution within the boiler furnace. In order to develop a on-line combustion tuning system, field test was conducted at operating power boiler. During the field test the exhaust gases' $O_2$, NOx and CO was monitored by using a spatially distributed monitoring grid located in the boiler's high temperature vestibule and upper convective back-pass region. At these locations, the flue gas flow is still significantly stratified, and air in-leakage is minimal which enables tracing of poor combustion zones to specific burners and over-fire air ports. using these monitored information we can improving combustion at every point within the furnace, therefore the boiler can operate at reduced excess $O_2$ and gas temperature deviation, reduced furnace exit gas temperature levels while also reducing localized hot spots, corrosive gas conditions, slag or clinker formation and UBC. Benefits include improving efficiency, reducing NOx emissions, increasing output and maximizing availability. Discussion concerning the reduction of greenhouse gases is prevalent in the world. When taking a practical approach to addressing this problem, the best way and short-term solution to reduce greenhouse gases on coal-fired power plants is to improve efficiency. From this point of view the real time optimized combustion tuning approach is the most effective and implemented with minimal cost.

  • PDF

A Study on the Improvement of Personal Information Protection in Small and Medium-sized Medical Institutions (중소형 의료기관의 개인정보 보안실태 및 개선방안)

  • Shin, Min ji;Lee, Chang Moo;Cho, Sung Phil
    • Convergence Security Journal
    • /
    • v.19 no.4
    • /
    • pp.123-132
    • /
    • 2019
  • Rapid developments of IT technology has been creating new security threats. There have been more attacks to get patients' sensitive personal information, targeting medical institutions that are relatively insufficient to prevent and defend against such attacks. Although the government has required senior general hospitals to get the ISMS certification since 2016, such a requirement has been burdensome for small and medium-sized medical institutions. Therefore, this study was designed to draw measures to identify and improve the privacy status of the medical institution by dividing it into management, physical and cyber areas for small and medium-sized medical institutions. The results of this study showed that the government should provide financial support and managerial supervision for the improvement of personal information protection of small and medium-sized medical institutions. They also suggested that the government should also provide medical security specialists, continuous medical security education, disaster planning, reduction of medical information management regulations not suitable for small and medium sized institutions.

Femtocell Searching Technique Using Synchronization Signals for Next-Generation Mobile Communication Systems (차세대 이동통신 시스템에서 동기신호를 이용한 펨토셀 탐색 기법)

  • Kim, Yeong Jun;Cho, Yong Soo
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.38A no.1
    • /
    • pp.44-57
    • /
    • 2013
  • In this paper, we propose a femtocell searching technique which can prevent a macrocell UE(user equipment) from losing synchronism to its serving macrocell near closed access femtocells in co-channel deployment due to the leakage of femtocell signals by using a CS(Common Signal). The CS, commonly transmitted by femtocells in a macrocell at the same time, enables the macrocell UEs to be kept synchronized with their serving macrocells since the CINR(Carrier to Interference and Noise Ratio) of base stations in macrocell can be kept high even near closed access femtocells. Also, the CS is designed in such a way that a macrocell UE can recognize the existence of femtocell by using the metric CSCINR(Common Signal Carrier to Interference and Ratio) measured with CS. In addition, the proposed femtocell searching technique can reduce the frequency of femtocell searching trial by using the metric on mobility of a macrocell UE defined in this paper, and the reduction of the frequency of handover trial can be also expected as a byproduct.

The Study of Optimized Combustion Tuning Method for Fossil Power Plant (발전용 보일러의 최적연소조정기법에 대한 실험적 연구)

  • Jung, Jae-Jin;Song, Jung-Il
    • Journal of the Korean Solar Energy Society
    • /
    • v.29 no.5
    • /
    • pp.45-52
    • /
    • 2009
  • Fossil power plants firing lower grade coals or equipped with modified system for $NO_x$ controls are challenged with maintaining good combustion conditions while maximizing generation and minimizing emissions. In many cases significant derate, availability losses and increase in unburned carbon levels can be attributed to poor combustion conditions as a result of poorly controlled local fuel and air distribution within the boiler furnace. In order to develop a on-line combustion tuning system, field test was conducted at operating power boiler. During the field test the exhaust gases' $O_2,\;NO_x$ and CO was monitored by using a spatially distributed monitoring grid located in the boiler's high temperature vestibule and upper convective rear pass region. At these locations, the flue gas flow is still significantly stratified, and air in-leakage is minimal which enables tracing of poor combustion zones to specific burners and over-fire air ports. using these monitored information we can improving combustion at every point within the furnace, therefore the boiler can operate at reduced excess $O_2$ and gas temperature deviation, reduced furnace exit gas temperature levels while also reducing localized hot spots, corrosive gas conditions, slag or clinker formation and UBC. Benefits include improving efficiency, reducing $NO_x$ emissions, increasing output and maximizing availability. Discussion concerning the reduction of greenhouse gases is prevalent in the world. When taking a practical approach to addressing this problem, the best way and short-term solution to reduce greenhouse gases on coal-fired power plants is to improve efficiency. From this point of view the real time optimized combustion tuning approach is the most effective and implemented with minimal cost.

Processed Panax ginseng, Sun Ginseng, Decreases Oxidative Damage Induced by tert-butyl Hydroperoxide via Regulation of Antioxidant Enzyme and Anti-apoptotic Molecules in HepG2 Cells

  • Lee, Hye-Jin;Kim, Jin-Hee;Lee, Seo-Young;Park, Jeong-Hill;Hwang, Gwi-Seo
    • Journal of Ginseng Research
    • /
    • v.36 no.3
    • /
    • pp.248-255
    • /
    • 2012
  • Potential antioxidant effect of processed ginseng (sun ginseng, SG) on oxidative stress generated by tert-butyl hydroperoxide (t-BHP) was investigated in HepG2 cells. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and lactate dehydrogenase (LDH) leakage test demonstrated that SG dose-dependently prevents a loss of cell viability against t-BHP-induced oxidative stress. Also, SG treatment dose-dependently relieved the increment of activities of hepatic enzymes, such as aspartate aminotrasferase and alanine aminotransferase, and lipid peroxidation mediated by t-BHP treatment in HepG2 cells. SG increased the gene expression of antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase. However, high dose of SG treatment caused decrease in mRNA level of glutathione peroxidase as compared to low dosage of SG-treated cells. The gene expression of glutathione reductase was found to be slightly increased by SG treatment. In addition, SG extract attributed its hepaprotective effect by inducing the mRNA level of bcl-2 and bcl-xL but reducing that of bax. But, the gene expression of bad showed no significant change in SG-treated HepG2 cells. These findings suggest that SG has hepatoprotective effect by showing reduction of LDH release, activities of hepatic enzymes and lipid peroxidation and regulating the gene expression of antioxidant enzymes and apoptosis-related molecules against oxdative stress caused by t-BHP in HepG2 cells.

THD Analysis of a Surface Textured Parallel Thrust Bearing: Effect of Dimple Radius and Depth (Surface Texturing한 평행 스러스트 베어링의 열유체윤활 해석: 딤플 반경과 깊이의 영향)

  • Jeong, YoHan;Park, TaeJo
    • Tribology and Lubricants
    • /
    • v.30 no.5
    • /
    • pp.303-310
    • /
    • 2014
  • In order to reduce friction and improve reliability, researchers have applied various surface texturing methods to highly sliding machine elements such as mechanical seals and piston rings. Despite extensive theoretical research on surface texturing, previous numerical results are only applicable to isothermal and iso-viscous conditions. Because the lubricant flow pattern of textured bearing surfaces is much more complicated than that for non-textured bearings, the Navier?Stokes equation is more suitable than the Reynolds equation for the former. This study carries out a thermohydrodynamic (THD) lubrication analysis to investigate the lubrication characteristics of a single micro-dimpled parallel thrust bearing cell. The analysis involves using the continuity, Navier?Stokes, energy, temperature?viscosity relation, and heat conduction equations with the commercial computational fluid dynamics (CFD) code FLUENT. This study discretizes these equations using the finite volume method and solves them using the SIMPLE algorithm. The results include finding the streamlines, pressure and temperature distributions, and variations in the friction force and leakage for various dimple radii and depths. Increasing the dimple radius and decreasing the depth causes a recirculation flow to form because of a strong vortex, and the oil temperature greatly increases compared with the non-textured case. The present numerical scheme and results are applicable to THD analysis of various surface-textured sliding bearings and can lead to further study.

Study on the Fire Safety Estimation for a Pilot LNG Storage Tank (PILOT LNG저장탱크의 화재안전성 평가에 관한 연구)

  • 고재선;김효
    • Fire Science and Engineering
    • /
    • v.18 no.3
    • /
    • pp.57-73
    • /
    • 2004
  • Quantitative safety analysis through a fault tree method has been conducted for a fire broken out over the spilling LNG from a pilot LNG tank, which may have 4 types of scenarios causing potentially risky results. When we consider LNG release from venting pipelines as a first event, any specific radius of Low Flammable Limit(LFL) has not been built up. The second case of LNG outflow from the rupture of storage tank which will be the severest has been analyzed and the results revealed various diffusion areas to the leaking times even with the same amount of LNG release. As a third case LNG leakage from the inlet/outlet pipelines was taken into consider. The results showed no significant differences of LFL radii between the two spilling times of 10 and 60 minutes. Hence, we have known the most affecting factor on the third scenario is an initial amount of LNG release. Finally, the extent of LFL was calculated when LNG pipelines around the dike area were damaged. In addition, consequence analysis has been also performed to acquire the heat radiation and flame magnitude for each case.