• Title/Summary/Keyword: Later Examination

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False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases

  • Dasheng Li;Dawei Wang;Jianping Dong;Nana Wang;He Huang;Haiwang Xu;Chen Xia
    • Korean Journal of Radiology
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    • v.21 no.4
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    • pp.505-508
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    • 2020
  • The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. The nucleic acid test or genetic sequencing serves as the gold standard method for confirmation of infection, yet several recent studies have reported false-negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). Here, we report two representative false-negative cases and discuss the supplementary role of clinical data with rRT-PCR, including laboratory examination results and computed tomography features. Coinfection with SARS-COV-2 and other viruses has been discussed as well.

A Case of Parotid Metastasis from Sebaceous Carcinoma of the Eyelids (이하선으로 전이된 안검의 피지샘 암종 1예)

  • Chae, Hee Sung;Yang, Hui Joon;Paik, Seung Won;Kim, Ji-Hoon
    • Korean Journal of Head & Neck Oncology
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    • v.36 no.2
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    • pp.21-25
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    • 2020
  • Sebaceous carcinoma is a relatively rare and aggressive malignant tumor. Periocular area (especially eyelid) is the most common lesion to occur, and the most common extraocular lesion is the parotid gland. Because the lesion also mimic other benign inflammatory diseases, this leads to delayed diagnosis or misdiagnosis. Here, we report a 58-year-old male patient who presented with a non-tender painless left parotid mass after wide excision of sebaceous carcinoma in the left eyelid two years ago. When he was diagnosed with sebaceous carcinoma of left eyelid, there was a small left parotid tumor on the computed tomography. But no further examination and treatment were performed. Two years later, physical examination revealed growing parotid tumor and multiple neck nodes on the left side. After radical parotidectomy and neck dissection, histological examination showed a sebaceous carcinoma and neck node metastasis. Considering the aggressiveness of sebaceous carcinoma, further evaluation for parotid glands should be considered when sebaceous carcinoma of the eyelid was discovered. Postoperative chemoradiotherapy was performed for disease control. Follow up after two years, and computed tomography showed no sign of recurrence.

Heterotopic bone formation in normal gastric cardiac mucosa (정상 위 분문부 점막에서 발견된 이소성 골 형성)

  • Eom, Seok Hyeon;Park, Chang Hwan;Chung, Duk Won;Lee, Sang Hyeok;Seo, Ji Young;Kim, Yeong Sung;Kwak, Dong Hyup;Kim, Jung Hee
    • Journal of Yeungnam Medical Science
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    • v.33 no.2
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    • pp.146-149
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    • 2016
  • Heterotopic bone formation in the gastrointestinal tract is a rare phenomenon. Most reported cases were associated with benign and malignant neoplasms, except for a case in which heterotopic bone formation was found in a patient with Barrett's esophagus. The exact pathogenesis of the disease has not yet been established. However, most heterotopic bones found in the gastrointestinal tract were associated with mucinproducing tumors of the appendix, colon, and rectum. Inflammation may also play a role in osseous metaplasia in a case with bone formation at the base of an ulcer in Barrett's esophagus. Here, we report on a patient with heterotopic bone formation in normal gastric cardiac mucosa. A 50-year-old female visited our hospital for a routine health examination. She had no gastrointestinal symptoms, and her physical examination, blood test, X-ray, urine, and stool examination results were normal. A 0.3 cm sized polypoid lesion located just below the squamocolumnar junction was observed on upper gastrointestinal endoscopy. A piece of biopsy was taken. Histologically, a lamella bone trabecula and chronic inflammatory cells were observed in the gastric cardiac mucosa. The follow-up endoscopy performed one month later showed no residual lesion.

Unifocal Langerhans Cell Histiocytosis of Frontal Bone in a Child (소아 전두골에 발생한 랑게르한스세포 조직구증)

  • Hong, Seong Jae;Cho, Sang Hun;Eo, Su Rak
    • Archives of Craniofacial Surgery
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    • v.14 no.1
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    • pp.69-72
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    • 2013
  • Lateral eyebrow mass with primary skull lesion are rare in pediatric population. Although epidermoid cyst and dermoid cyst are the most commonly encountered skull lesions in pediatric population, Langerhans cell histiocytosis (LCH) is rarely reported. We report a case of LCH arising from the lateral eyebrow with osteolytic lesion involving the frontal bone. A 5-year-old boy was presented with a hard, fixed mass in his lateral eyebrow. Contrast magnetic resonance imaging revealed inhomogeneous enhancement of the mass with direct invasion of the frontal bone and adjacent dura mater. Under general anesthesia, linear incision at the lateral eyebrow region was made. Intraoperative evaluation revealed hard, fixed and well-defined soft tissue mass. The final extirpated mass was $2.5{\times}2.4cm$ in size, and was accompanied by a $1{\times}1cm$ sized defect on the frontal bone with intact dura mater. The surgical wound was closed primarily by a layer-by-layer fashion. Histologic examination was later performed for definite diagnosis. The histologic examination revealed abnormal proliferation of Langerhans cell with granuloma formation. Radionuclide bone scan and positron emission tomography was taken and revealed free of multi-organ involvement. At 3 months after surgery, natural looking contour at the lateral eyebrow region was observed with no tumor recurrence. Differential diagnosis of the hard and fixed mass at the lateral eyebrow region affecting the primary skull lesion from pediatric population includes epidermoid cyst, dermoid cyst and LCH. Generally, brief physical examination with plain X-ray view can be performed for clinical evaluation, but for a definite diagnosis, contrast MRI may be helpful.

The Differential Diagnosis between Allergic and Nonallergic Rhinitis and Management : Focusing on Current update of Medical History and Physical Examination (알레르기 비염과 비알레르기 비염의 감별 진단 및 관리 : 병력 청취 및 진찰 소견에 대한 최신지견 중심으로)

  • Hong, Eu-Gene;Shin, Jun-Hyuk;Jeong, Woo-Yeol;Nam, Hae-Jeong;Kim, Kyu-Seok;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.27 no.4
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    • pp.101-109
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    • 2014
  • Objective : The purpose of this study is to summarize the differential diagnosis between allergic and nonallergic rhinitis and suggest management. Methods : We reviewed the current update of medical history and physical examination for allergic and nonallergic rhinitis. Then we analyzed clinical characteristics according to onset age, gender incidence and state of nasal symptoms, etc. Results : 1. Patients with nonallergic rhinitis tend to develop symptoms at a later age(>35 years of age), and there is a female-to-male incidence ratio for nonallergic rhinitis of 2:1 to 3:1. 2. Patients with nonallergic rhinitis report nasal congestion, nasal rhinorrhea and more often report postnasal drip rather than sneezing and itching, which are predominant symptoms of allergic rhinitis. And the nasal mucosa in nonallergic rhinitis usually looks normal. 3. Patients with nonallergic rhinitis have few complaints of concomitant symptoms of allergic symptoms and the absence of other atopic diseases in the patient or in the family supports the diagnosis of nonallergic rhinitis. 4. Common triggers of nonallergic rhinitis are nonspecific irritant exposures and many patients with nonallergic rhinitis find that antihistamines have no benefit. Conclusions : The differential diagnosis between allergic and nonallergic rhinitis is clinical and relies on a detailed medical history and physical examination.

The Analysis on the Emotional Evaluation Methods of Environmental Design Elements Using the Eye Mark Recorder and the Repertory Grid Method

  • Jung, A-Young
    • International Journal of Contents
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    • v.7 no.4
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    • pp.77-83
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    • 2011
  • This paper is an inquiry into the human sensibility on view from high-rise housing in a viewpoint of architectural environment design that pay attention to multi-family high-rise housing which is becomes a trend in recent years. And this paper is the fundamental approach for applying this result to later architectural environmental plan of multi-family high-rise housing. In this paper, we used repertory grid method as a cognitive psychological way of analysis and eye mark recorder measurement experiments as a physiological way of examination. In the conclusions, examined human sensibilities on views-focused on the analysis result of eye mark recorder measurement experiments through repertory grid method that are carried on the main subject-and described problems after this and possibilities in the same time.

The Evaluation of Paraphilia and Paraphilic Disorder (성도착증과 성도착 장애의 평가)

  • Lee, Jang Kyu;Lee, Soo Jung;Lim, Myung Ho
    • Anxiety and mood
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    • v.12 no.2
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    • pp.86-96
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    • 2016
  • Paraphilia and paraphilic disorder is one of mental disorders making it difficult to assess and treat. Recently, a number of methods for assessing the paraphilia are being developed gradually outside south Korea. And the reliability and validity of various assessment tools are being reported. The standardization of the assessments and questionnaires was not made yet. For assessment of paraphilia that has been reported from abroad, the author comprehensively organized clinical interview, physical examination, psycho-physiological methods, self-reporting scale of sexual thoughts, fantasies and attitudes and multiple self-reporting scale of sexual interests and described the clinical significance of the assessment tools. The national standardization of both self-reported questionnaire and physical evaluations is expected to be completed later.

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Examination of the Practical Model for STEAM Education through Case Studies (STEAM 교육 사례 분석을 통한 실천 모형 탐색)

  • KIM, Ji-Won;WON, Hyo-Heon
    • Journal of Fisheries and Marine Sciences Education
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    • v.27 no.6
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    • pp.1676-1684
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    • 2015
  • The study was conducted to develop the Practical STEAM education Model. To achieve the goal, we did analysis advanced research, comprehensive review of literature, consultation with research team. As a result, the Practical STEAM education Model is consisted as follow; integrated subjects, object, value and aim, curriculum(method, assessment). The result has defined the concept and theoretical framework of STEAM education curriculum as application aspects, it would help to develop the program with STEAM education curriculum. Later in this study is to develop programs and organize. and It intends to become the base to be able to interest and interest in science education by structured around the status of problems that can be found in the life of around themes STEAM.

HORNER'S SYNDROME AFTER ORTHOGNATHIC SURGERY (악교정수술 후 발생한 호르너 증후군)

  • Kim, Woon-Kyu;Kim, Su-Gwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.27 no.2
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    • pp.184-188
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    • 2001
  • Horner's syndrome as a complication of orthognathic surgery is given little attention of head and neck surgery and is a relatively benign and transient condition. A 18-year-old male referred to our department with long and anteriorly projected chin. The cephalometric evaluation revealed a skeletal Class III relationship. A 10-mm setback of the mandible to eliminate Class III relationship and 4-mm vertical reduction genioplasty were performed. Three weeks after operation, the patient was recognized anhidrosis in left face and the head, and ptosis of left eye. The trauma to cervical sympathetic nerve during left sagittal split ramus osteotomy was thought to be the cause of Horner's syndrome. Patient was treated by dermatologic and opthalmologic care. Follow-up examination 8 months later, he was recovery of horner's symptom.

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Fine Needle Aspiration Cytology of Ganglioneuroma - A Case Report - (신경절신경종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Kim, Hee-Kyung;Jin, So-Young;Lee, Dong-Wha
    • The Korean Journal of Cytopathology
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    • v.14 no.1
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    • pp.12-16
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    • 2003
  • Ganglioneuroma is a well-differentiated, benign tumor of the sympathetic nervous system. These tumors belong to a family of neoplasm that exhibit a wide range of differentiation, with neuroblastoma at one end and ganglioneuroma at the other. Because it share morphologic features with other both benign and malignant neural tumors, accurate preoperative diagnosis is often difficult. Nonetheless, it is critical for proper management. Fine needle aspiration cytology (FNAC) in the diagnosis of the ganglioneuroma has been a little documented. We describe a case of mediastinal ganglioneuroma in a 33-month-old girl. The diagnosis was suggested on FNAC and was confirmed by histopathologic examination later.