• Title/Summary/Keyword: Laser parameters

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Laser Induced Microjet Drug Delivery System: Drug Permeation Depending on Laser Wavelength and Pulse Duration (레이저 유도 마이크로젯을 활용한 약물 전달 방식: 레이저 파장 및 펄스길이에 따른 약물 침투 분석)

  • Jang, Hun jae;Ham, Hwi chan;Yoh, Jai ick
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.41 no.7
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    • pp.463-468
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    • 2017
  • For transdermal drug delivery, needless injection system is composed of laser and microjet injector. Main mechanism of microjet injector is the laser-induced bubble. Nd:YAG and Er:YAG laser are used as a power source. Laser parameters such as pulse duration and wavelength are considered, which are core parameters to control the bubble motion. The Nd:YAG laser, pulse duration is short than bubble life time making cavitation like bubble while in Er:YAG laser, long pulse duration and high absorption in water drive bubble as a boiling bubble. Detailed motion of bubble and microjet is captured by the high speed camera. So it is observed that microjet characteristics are determined by the bubble behavior. The performance of drug delivery system is evaluated by fluorescent staining of guinea pig skin.

Analysis of Scaling Parameters of the Batch Unscented Transformation for Precision Orbit Determination using Satellite Laser Ranging Data

  • Kim, Jae-Hyuk;Park, Sang-Young;Kim, Young-Rok;Park, Eun-Seo;Jo, Jung-Hyun;Lim, Hyung-Chul;Park, Jang-Hyun;Park, Jong-Uk
    • Journal of Astronomy and Space Sciences
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    • v.28 no.3
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    • pp.183-192
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    • 2011
  • The current study analyzes the effects of the scaling parameters of the batch unscented transformation on precision satellite orbit determination. Satellite laser ranging (SLR) data are used in the orbit determination algorithm, which consists of dynamics model, observation model and filtering algorithm composed of the batch unscented transformation. TOPEX/Poseidon SLR data are used by utilizing the normal point (NP) data observed from ground station. The filtering algorithm includes a repeated series of processes to determine the appropriate scaling parameters for the batch unscented transformation. To determine appropriate scaling parameters, general ranges of the scaling parameters of ${\alpha}$, ${\beta}$, k, $\lambda$ are established. Depending on the range settings, each parameter was assigned to the filtering algorithm at regular intervals. Appropriate scaling parameters are determined for observation data obtained from several observatories, by analyzing the relationship between tuning properties of the scaling parameters and estimated orbit precision. The orbit determination of satellite using the batch unscented transformation can achieve levels of accuracy within several tens of cm with the appropriate scaling parameters. The analyses in the present study give insights into the roles of scaling parameters in the batch unscented transformation method.

The Study on Laser Cladding of Heat Resisting Steel Using EuTroLoy 16006 Powder(I) - Characteristics of 1 Pass Clad Layer with Process Parameters - (EuTroLoy 16006 분말을 이용한 내열강의 레이저 클래딩에 관한 연구(I) - 공정변수에 따른 1패스 클래드 층의 특성 -)

  • Kim, Jong Do;Lee, Eun Jin;Kim, Cheol Gyu
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.4
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    • pp.299-305
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    • 2017
  • Re-engineering is gaining attention due to severe environmental pollution and economic crisis. Although re-engineering in shipbuilding has been carried out steadily, technological advancements, domestic ship repair and maintenance industries are not as prevalent as shipbuilding industries. In order to solve this problems, laser cladding can significantly aid with technical development. Laser cladding produces an outstanding clad layer with minimal dilution and little porosity. In this study, prior to applying laser cladding to an exhaust valve face, the effects of various parameters that affect the characteristics of the 1 pass clad layer were investigated. When laser power was increased, the clad layer width became broader and the height was decreased. In addition, it was identified that the hardness of the clad layer was inversely proportional to the power, and the entire clad layer was diluted through an EDS chemical composition analysis.

Efficacy of Portable Low Power Laser Therapy on Pain and Functions in Chronic Low Back Pain (만성 요통 환자에서의 휴대용 저출력 레이저 치료기의 통증 및 기능 효과)

  • Cho, Yeon Wook;Kim, Tae Hee;Lim, Oh Kyung;Lee, Ju Kang;Park, Ki Deok
    • Clinical Pain
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    • v.19 no.1
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    • pp.1-7
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    • 2020
  • Objective: A prospective, assessor-blinded, randomized controlled trial was conducted in patients with chronic low back pain to evaluate the efficacy of portable low power laser therapy (LPLT) and the effect when combined with exercise therapy on pain and functions. Method: 60 patients were recruited and 56 patients, excluding 4 dropouts, were randomly allocated to the LPLT group (Group 1: 19 patients), placebo laser therapy with exercise group (Group 2: 18 patients), and LPLT with exercise group (Group 3: 19 patients). Laser therapy and exercise was performed five times a week for 4 weeks. Visual analogue scale (VAS), Schober test, lumbar range of motion (ROM) measures (flexion, extension and lateral flexion), Oswestry Disability index (ODI) were measured at baseline, at 4 weeks after intervention, and at 6 weeks after 2 weeks of no intervention. Results: Statistically significant improvements were noted in all group by time interaction with respect to all outcome parameters (p<0.05). All parameters in each group improved not only in the period of treatment (4 weeks), but also in the final evaluation (6 weeks) 2 weeks after the end of treatment. Post-hoc analysis showed statistically significant difference between the LPLT with exercise group and the other groups in all outcome parameters except for the ODI at 4 weeks and at 6 weeks. Conclusion: Portable LPLT is effective treatment in reducing pain and improving lumbar ROM and with exercise is more effective than laser or exercise monotherapy for the chronic low back pain patients.

The Microstructure Characteristics of Laser Remelted Cobalt-Based Hardfacing Alloys (레이저 Remelting 처리된 Co 기지 하드페이싱 합금의 미세조직 특성)

  • Han Won Jin;Kim Woo Sung
    • Laser Solutions
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    • v.7 no.2
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    • pp.27-38
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    • 2004
  • Laser remelting of surface of cobalt-based hardfacing alloy can eliminate impurities and cracks and improve the wear resistance. In this present study, Stellite ${\sharp}6\;and\;{\sharp}21$ harfacing alloys were remelted by a 3kW CO2 laser. Hardness distribution and microstructures in the laser remelted zone was investigated. Our results showed that in proper laser parameters laser remelted surface of hardfacing alloy had more refined microstructure and more increased micro-hardness than the base material.

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Laser Welding Application in Car Body Manufacturing

  • Shin, H.O.;Chang, I.S.;Jung, C.H.
    • International Journal of Korean Welding Society
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    • v.3 no.1
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    • pp.2-7
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    • 2003
  • Laser welding application for car body manufacturing has many advantages in the stiffness and the lightness of vehicle, the productivity of assembly line, and the degree of freedom in design. This presentation will express the innovation of car body manufacturing including parameter optimization, process modeling, and system integration. In this application the investment for systems was cut down dramatically by real time switching over the laser path between two welding stations. Points of technical discussion are as follows; optimization of parameters such as laser power, robot speed and trajectory, compact and useful design of jig & fixture to assure welding quality for 3 sheet-layer zinc-coated steel, system integration between 4㎾ Nd:YAG laser device and the other systems, on-line real time welding quality monitoring system, perfect safety standards for high power laser, minimization of consumption costs such as arc lamp, protective glass for optic, etc. This application was successfully launched mass production line in 2001. The laser-welded line of side panel consists of 122 stitches totally. And the length is about 2.4m.

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APPLYING LASER-ARC HYBRID WELDING TECHNOLOGY FOR LAND PIPELINES

  • Booth, G-S;Howse, D-S;Woloszyn, A-C;Howard, R-D
    • Proceedings of the KWS Conference
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    • 2002.10a
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    • pp.169-175
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    • 2002
  • World demand for natural gas has generated the need for many new land transmission pipelines to be installed in the next decade or so. Although mechanized gas metal arc welding is well developed, there are opportunities for cost savings by using alternative welding processes. Hybrid Nd:YAG laser - gas metal arc welding enables fibre optic delivery of the laser energy to a robotic welding head to be combined with the addition of extra energy and a consumable to produce good quality, deep penetration welds in a single pass. The present paper describes initial procedure development to optimize the laser and gas metal arc welding parameters for making joints in pipeline steel. Satisfactory joint quality was obtained and it is intended to develop the process to prototype field trials.

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Laser micromachining of micron-size aperture for electron beam microcolumn application using the piezo-switched Nd:YAG laser (Piezo Q-Switched Nd:YAG 레이저에 의한 초미니 전자빔 장치용 Micron-Size Aperture의 레이저 미세가공)

  • 안승준;김대욱;김호섭;최성수
    • Journal of the Korean Vacuum Society
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    • v.8 no.4A
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    • pp.456-460
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    • 1999
  • Experimental studies of laser micromachining on Mo diaphragm using piezo Q-switched Nd:YAZ laser have been performed. Application of miniaturized micorcolumn electron gun arrays as a potential electron beam lithography or portable mini-scanning electron microscope (SEM) application have recently extensively examined. The conventional microcolumn fabrication technique would give a limitation on the minimization of aberration, In this paper, we obtained 20~30 $\mu \textrm m$aperture of laser micromachining on Mo diaphragm using piezo Q-swithed Nd:YAG laser. The geometrical figures, such as the diameter and the preciseness of the drilled aperture are dependent upon the total energy of the laser pulse train, laser pulse width, and the diameter of laser spot in addition to the materials-dependent parameters.

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A Study on Fabrication of Conductor Patterns on AlN Ceramic Surface by Laser Direct Writing (레이저 직접묘화법에 의한 AlN 기판상의 전도성 패턴 제작에 관한 연구)

  • Lee, Je-Hoon;Seo, Jung;Han, Yu-Hee
    • Laser Solutions
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    • v.3 no.2
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    • pp.25-33
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    • 2000
  • One of perspective direction of microfabrication is direct laser writing technology that allows to create metal, semiconductive and dielectric micropatterns on substrate surface. In this work, a two step method, the combination of seed forming process, in which metallic Al seed was selectively generated on AlN ceramic substrate by direct writing technique using a pulsed Nd : YAG laser and subsequent electroless Ni plating on the activated Al seed, was presented. The effects of laser parameters such as pulse energy, scanning speed and pulse frequency on shape of Alseed and conductor line after electroless Ni plating were investigated. The nature of the laser activated surface is analyzed from XPS data. The line width of this metallic Al and Ni is analyzed using SEM. As a results, Al seed line with 24㎛ width and 100㎛ isolated line space is obtained. Finally, laser direct writing can be applied in the field between thin and thick film technique in electronic industry.

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Micro patterning of conductor line by laser induced forward transfer(LIFT) (LIFT 방법에 의한 전도성 미세 패터닝 공정 연구)

  • 이제훈;한유희
    • Laser Solutions
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    • v.2 no.3
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    • pp.52-61
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    • 1999
  • The laser induced forward transfer(LIFT) technique employs a pulsed laser to transfer parts of a thin metal film from an optically transparent target onto an arbitrary substrate in close proximity to the metal film on the target. In this work, a two-step method, the combination of LIFT process, in which a Au film deposited on the $Al_2$O$_3$ substrate by Nd:YAG laser and subsequent Au electroless metal plating on the by LIFT process generated Au seed, was presented. The influence of laser parameters, wavelength, laser power, film thickness and overlap ratio of pulse tracks, on the shapes of deposit and conductor line after electroless plating is experimentally studied. As a results, the threshold power densities for ablation, deposition and metallization were determined and comparison of threshold value between the wave length 1064nm and the second harmonic generated 532nm. In odor to determine a possible application in the electronic industry, a smallest conduct spot size, line width and isolated line space were generated.

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