• Journal of Periodontal and Implant Science
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• 제50권6호
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• pp.392-405
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• 2020

Purpose: Titanium implants are widely used in the treatment of dentition defects; however, due to problems such as osseointegration failure, peri-implant bone resorption, and periimplant inflammation, their application is subject to certain restrictions. The surface modification of titanium implants can improve the implant success rate and meet the needs of clinical applications. The goal of this study was to evaluate the effect of the use of porous titanium with a chitosan/hydroxyapatite coating on osseointegration. Methods: Titanium implants with a dense core and a porous outer structure were prepared using a computer-aided design model and selective laser sintering technology, with a fabricated chitosan/hydroxyapatite composite coating on their surfaces. In vivo and in vitro experiments were used to assess osteogenesis. Results: The quasi-elastic gradient and compressive strength of porous titanium implants were observed to decrease as the porosity increased. The in vitro experiments demonstrated that, the porous titanium implants had no biological toxicity; additionally, the porous structure was shown to be superior to dense titanium with regard to facilitating the adhesion and proliferation of osteoblast-like MC3T3-E1 cells. The in vivo experimental results also showed that the porous structure was beneficial, as bone tissue could grow into the pores, thereby exhibiting good osseointegration. Conclusions: Porous titanium with a chitosan/hydroxyapatite coating promoted MC3T3-E1 cell proliferation and differentiation, and also improved osseointegration in vitro. This study has meaningful implications for research into ways of improving the surface structures of implants and promoting implant osseointegration.

• Current Optics and Photonics
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• 제3권3호
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• pp.256-262
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• 2019

Extensive tumor resection accompanied by radiotherapy and chemotherapy is the standard of care for malignant gliomas. However, there is a significant obstacle to the complete resection of the tumor due to the difficulty of distinguishing tumor and normal brain tissue with a conventional surgical microscope. Recently, multiple studies have shown the possibility of fluorescence-guided surgery in malignant gliomas. The most used fluorescence dyes for brain tumor surgery are 5-aminolevulinic acid (5-ALA) and indocyanine green (ICG). In this paper, a new fluorescence guided operation system, which can detect both 5-ALA and ICG fluorescent images simultaneously, is presented. This operation system consists of light emitting diodes (LEDs) which emits 410 nm and 740 nm wavelengths. We have performed experiments on rats in order to verify the operation of the newly developed operation system. Oral administration and imaging were performed to observe the fluorescence of 5-ALA and ICG fluorescence in rats. When LEDs at wavelengths of 410 nm and 740 nm were irradiated on rats, 628 nm wavelength with a violet fluorescence color and 825 nm wavelength with a red fluorescence color were expressed in 5-ALA and ICG fluorescent material, respectively, thus we were able to distinguish the tumor tissues easily. Previously, due to the poor resolution of the conventional surgical microscope and the fact that the color of the vein is similar to that of the tumor, the tumor resection margin was not easy to observe, thus increasing the likelihood for cancer recurrence. However, when the tumor is observed through the fluorescence guided operation system, it is possible to easily distinguish the color with the naked eye and it can be completely removed. Therefore, it is expected that surgical removal of cancerous tumors will be possible and surgical applications and surgical microscopes for cancer tumor removal surgery will be promising in the future.

• Imaging Science in Dentistry
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• 제51권2호
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• pp.107-115
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• 2021

Purpose: This study aimed to demonstrate the presence of dental caries through a photoacoustic imaging system with visible and near-infrared wavelengths, highlighting the differences between the 2 spectral regions. The depth at which carious tissue could be detected was also verified. Materials and Methods: Fifteen permanent molars were selected and classified as being sound or having incipient or advanced caries by visual inspection, radiography, and optical coherence tomography analysis prior to photoacoustic scanning. A photoacoustic imaging system operating with a nanosecond pulsed laser as the light excitation source at either 532 nm or 1064 nm and an acoustic transducer at 5 MHz was developed, characterized, and used. En-face and lateral(depth) photoacoustic signals were detected. Results: The results confirmed the potential of the photoacoustic method to detect caries. At both wavelengths, photoacoustic imaging effectively detected incipient and advanced caries. The reconstructed photoacoustic images confirmed that a higher intensity of the photoacoustic signal could be observed in regions with lesions, while sound surfaces showed much less photoacoustic signal. Photoacoustic signals at depths up to 4 mm at both 532 nm and 1064 nm were measured. Conclusion: The results presented here are promising and corroborate that photoacoustic imaging can be applied as a diagnostic tool in caries research. New studies should focus on developing a clinical model of photoacoustic imaging applications in dentistry, including soft tissues. The use of inexpensive light-emitting diodes together with a miniaturized detector will make photoacoustic imaging systems more flexible, user-friendly, and technologically viable.

• Journal of Ceramic Processing Research
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• 제20권6호
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• pp.589-596
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• 2019

Pigments with minute particle sizes, such as carbon black (CB) and pigment red 48:2 (P.R.48:2), are the most important types of pigment and have been widely used in many industrial applications. However, minute particles have large surface areas, high oil absorption and low surface energy. They therefore tend to be repellent to the vehicle and lose stability, resulting in significant increases in viscosity or reaggregation in the vehicle. Therefore, finding the best way to improve the dispersion properties of minute particle size pigments presents a major technical challenge. In this study, minute particle types of CB and P.R.48:2 were treated with nitrogen gas plasma generated via radio frequency-plasma enhanced chemical vapor deposition (RF-PECVD) to increase the dispersion properties of minute particles in deionized (DI) water. The morphologies and particle sizes of untreated and plasma treated particles were evaluated using scanning electron microscopy (SEM) and atomic force microscopy (AFM). The average distributions of particle size were measured using a laser particle sizer. Fourier transform infrared spectroscopy was carried out on the samples to identify changes in molecular interactions during plasma processing. The results of our analysis indicate that N2 plasma treatment is an effective method for improving the dispersibility of minute particles of pigment in DI water.

• 한국산림과학회지
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• 제110권1호
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• pp.72-81
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• 2021

본 연구는 다양한 임목 정보를 측정하고 효과적으로 관리하기 위해 스마트폰 애플리케이션과 웹 애플리케이션 서버(Web Application Server, WAS)를 개발하였다. 수고, 방위, 고도, 경사, 위치 좌표는 스마트폰에 내장된 동작센서를 통해 취득된 각도를 삼각법에 적용하여 측정하였으며, 흉고직경 및 거리는 Google AR Core에서 제공하는 AR API(Application Programming Interface)를 응용하여 측정할 수 있도록 하였다. 웹 애플리케이션 서버는 스마트폰이 측정한 데이터를 수신하여 저장, 조회, 출력하고 수목의 위치를 카카오 맵에 표시할 수 있도록 개발하였다. 또한, 개발된 애플리케이션의 정확성을 평가하기 위해 인공 침엽수림에서 잣나무 90본, 천연 혼효림에서 무작위로 90본을 선정하여 버텍스 및 윤척과 비교하였다. 비교 결과, 흉고직경과 수고 모두 95% 수준에서 유의한 결과를 나타내었으며, 흉고직경의 경우 인공 침엽수림이 평균 0.6745 cm, 천연 혼효림에서는 평균 1.0139 cm의 오차를 보였다. 수고는 인공 침엽수림이 평균 0.6714 cm, 천연 혼효림은 평균 1.3297 m의 오차를 보였다.

• 대한임베디드공학회논문지
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• 제17권1호
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• pp.9-17
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• 2022

As the COVID-19 pandemic situation worsens, the time spent indoors increases, and the exposure to indoor environmental pollution such as indoor air pollution and noise also increases, causing problems such as deterioration of human health, stress, and discord between neighbors. This paper designs and implements a system that measures and monitors indoor air quality and noise, which are representative evaluation criteria of the indoor environment. The system proposed in this paper consists of a particulate matter measurement subsystem that measures and corrects the concentration of particulate matters to monitor indoor air quality, and a noise measurement subsystem that detects changes in sound and converts it to a sound pressure level. The concentration of indoor particulate matters is measured using a laser-based light scattering method, and an error caused by temperature and humidity is compensated in this paper. For indoor noise measurement, the voltage measured through a microphone is basically measured, Fourier transform is performed to classify it by frequency, and then A-weighting is performed to correct loudness equality. Then, the RMS value is obtained, high-frequency noise is removed by performing time-weighting, and then SPL is obtained. Finally, the equivalent noise level for 1 minute and 5 minutes are calculated to show the indoor noise level. In order to classify noise into direct impact sound and air transmission noise, a piezo vibration sensors is mounted to determine the presence or absence of direct impact transmitted through the wall. For performance evaluation, the error of particulate matter measurement is analyzed through TSI's AM510 instrument. and compare the noise error with CEM's noise measurement system.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.1075-1084
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• 2022

The use of Hi-Tech in cultural heritage preservation and the promotion of cultural heritage values in general, particularly artifacts, opens new opportunities for attracting tourists while also posing a challenge due to the need to reward high-quality excursions to visitors historical and cultural values. Building Information Modeling (BIM) and Hi-Tech in new building management have been widely adopted in the construction industry; however, Historic Building Information Modeling (HBIM) is an exciting challenge in 3D modeling and building management. For those reasons, the Scan-to-HBIM approach involves generating an HBIM model for existing buildings from the point cloud data collected by Terrestrial 3D Laser Scanner integrated with Virtual Reality (VR), Augmented Reality (AR), contributes to spatial historic sites simulation for virtual experiences. Therefore, this study aims to (1) generate the application of Virtual Reality, Augmented Reality to Historic Building Information Modeling - based workflows in a case study which is a monument in the city; (2) evaluate the application of these technologies to improve awareness of visitors related to the promotion of historical values by surveying the experience before and after using this application. The findings shed light on the barriers that prevent users from utilizing technologies and problem-solving solutions. According to the survey results, after experiencing virtual tours through applications and video explanations, participant's perception of the case study improved. When combined with emerging Hi-Tech and immersive interactive games, the Historic Building Information Modeling helps increase information transmission to improve visitor awareness and promote heritage values.

• 한국지반공학회논문집
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• 제25권8호
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• pp.5-21
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• 2009

암반에 근입된 현장타설말뚝의 주면마찰력에 대한 최근의 연구결과에 따르면 주면마찰력은 암석의 일축압축강도 외에 굴착면의 거칠기, 암반의 재료특성, 초기 수직음력, 말뚝의 직경, 암반의 절리 및 풍화도 등에 크게 영향을 받는 것으로 보고되어 있다. 지금까지 개발된 굴착면 거칠기 시스템들은 공기 중에서만 측정가능하므로 현장의 굴착공내에서 직접 측정하는 것은 불가능하였다. 따라서, 본 연구에서는 수중에서 사용가능한 굴착공 벽면거칠기 측정 시스템(BKS-LRPS)을 개발하였으며, 특수 제작된 보정장치를 통하여 여러 가지 경우에 대한 검증을 수행하였다. 연구결과에 의하면, 개발된 BKS-LRPS는 장치제작조건 및 현장조건을 반영하도록 계획된 검증조건들에 대하여 유효측정영역을 제시할 수 있었다.

• Journal of Microbiology and Biotechnology
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• 제33권6호
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• pp.753-759
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• 2023

The genus Paenibacillus contains a variety of biologically active compounds that have potential applications in a range of fields, including medicine, agriculture, and livestock, playing an important role in the health and economy of society. Our study focused on the bacterium SS4^T (KCTC 43402^T = GDMCC 1.3498^T), which was characterized using a polyphasic taxonomic approach. This strain was analyzed using antiSMASH, BAGEL4, and PRISM to predict the secondary metabolites. Lassopeptide clusters were found using all three analysis methods, with the possibility of secretion. Additionally, PRISM found three biosynthetic gene clusters (BGC) and predicted the structure of the product. Genome analysis indicated that glucoamylase is present in SS4^T. 16S rRNA sequence analysis showed that strain SS4^T most closely resembled Paenibacillus marchantiophytorum DSM 29850^T (98.22%), Paenibacillus nebraskensis JJ-59^T (98.19%), and Paenibacillus aceris KCTC 13870^T (98.08%). Analysis of the 16S rRNA gene sequences and Type Strain Genome Server (TYGS) analysis revealed that SS4^T belongs to the genus Paenibacillus based on the results of the phylogenetic analysis. As a result of the matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF/MS) results, SS4^T was determined to belong to the genus Paenibacillus. Comparing P. marchantiophytorum DSM 29850^T with average nucleotide identity (ANI 78.97%) and digital DNA-DNA hybridization (dDDH 23%) revealed values that were all less than the threshold for bacterial species differentiation. The results of this study suggest that strain SS4^T can be classified as a Paenibacillus andongensis species and is a novel member of the genus Paenibacillus.

• 한국정보통신학회논문지
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• 제1권1호
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• pp.85-93
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• 1997

본 논문에서는, 부분응답 전송시스템의 일반화된 모델을 수정하여 순환적 구조로 설정하고, 이를 극초단펄스의 형성과정에 적용함으로써, 펄스의 폭에 따라 그 스펙트럼을 용이하게 얻어낼 수 있는 새로운 방법을 제안하였다. 이 방법은, 시간영역에서 폭이 매우 좁기 때문에 그 주파수영역의 정확한 형태를 평가하기 어려운 극초단펄스의 스펙트럼 분석을 위하여 편리하게 사용될 수 있다. 또한, 여기서 제시하는 방법은 순환적 알고리듬을 제공하므로, 연속미분법이나 콘볼루션에 의한 방법 등 기존의 알고리듬에 비하여 수치해석적으로 용이하며 이론적 접근에 있어서도 매우 편리하게 이용될 수 있다. 만일, 극초단펄스의 기본형태가 절단형fourier 급수로 정확히 표현되거나, 정형화된 펄스에 의하여 근사화될 수 있다면, 본 논문의 방법은 매우 편리하게 적용된다. 기본형태를 나타내는 Fourier 급수가 소량의 항에서 절단될수록 스펙트럼은 단순한 연산에 의하여 얻어진다. 또한, 다양한 형태의 극초단펄스를 표현하기 위한 방편으로, 최소대역 부분응답 전송시스템의 보편적 형태인 9-Type을 여기에 적용하고, 차수를 증가시켜 FWHM 폭을 현저히 감소시키는 형태를 찾아, 그 스펙트럼을 유도하는 일반적 알고리듬을 제시하였다.