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Influence of Extracts of Biotae Orientalis on the Efficiency of Hair Growth in Hair Removed C57BL/6N Mice (측백엽(側柏葉) 추출물의 발모효과(發毛效果)에 관한 실험적 연구)

  • Tak, Min-Jin;Jung, Il-Kook;Kim, Dae-Keun;Jung, Han-Sol;Lee, Chang-Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.1
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    • pp.136-144
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    • 2007
  • Biotae Orientalis has been widely used for treatment of relaxion of smooth muscle, gastrointestinal hemorrhage and alopecia in Oriental Medicine. This experiment examined the effect of an extracts, obtained from the acetone and MeOH extracts of dried or fresh Biotae Orientalis, on hair growing activity of the C57BL/6N mice after topical application to skin. First, We examined on hair growth activity of extracts of Biotae Orientalis compare to control and 1% minoxidil groups. Second, We investigated on the number of hair follicle and mast cells after topical application of extracts of the Biotae Orientalis to skin for 16 day. Third, We investigated immunoreactive density of vascular endothelial growth factor(VEGF), protein kinase C-${\alpha}$(PKC-${\alpha}$) and stem(mast) cell factor(SCF) in skin of C57BL/6N mice by immunohistochemical methods. I fourth investigated changes of subpopulation of splenocytes and thymocytes in C57BL/6N mice for 16day using laser flow cytometry. The results were as follows : Hair growing effect of acetone and MeOH extracts of dried and fresh Biotae Orientalis was observed in 70%, 90% and 60% in hair removed skin area in 16 day respectively. Immunoreactive density of VEGF and PKC-${\alpha}$ in skin of experimental groups was weakly stained compare to control group in 10 day. Immunoreactive density of stem cell factor in skin of experimental group was heavily stained compare to control group in 10 day. Splenic TH/TC Iymphocytes of lived MeOH extracts group significantly increased compare to control group. TH cells in thymic T lymphocytes were increased compare to control group. These experiment suggest that acetone and MeOH extracts of Biotae Orientalis may be used for topical treatment of alopecia areata.

An Error Examination of 3D Face Automatic Recognition (3차원 안면자동인식기의 형상복원 오차검사)

  • Suk, Jae-Hwa;Cho, Kyung-Rae;Cho, Yong-Beum;Yoo, Jung-Hee;Kwak, Chang-Kyu;Lee, Soo-Kyung;Kho, Byung-Hee;Kim, Jong-Won;Kim, Kyu-Kon;Lee, Eui-Ju
    • Journal of Sasang Constitutional Medicine
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    • v.18 no.2
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    • pp.41-49
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    • 2006
  • 1. Objectives The Face is an important standard for the classification of Sasang Contitutions. We are developing 3D Face Automatic Recognition Apparatus to analyse the facial characteristics. So We should examine a shape demobilization error of 3D Face Automatic Recognition Apparatus. 2. Methods We compared facial shape data be demobilized by 3D Face Automatic Recognition Apparatus with facial shape data that be demobilized by 3D laser scanner. The subject was two korean men. And We analysed the average error and the maximum error of two data. In this process, We used one datum point(the peak of nose) and two datum line(vertical section and horizontal section). 3. Results and Conclusions In each this comparison, the average error of vertical section was 1.962574mm and 2.703814mm. and the maximum error of vertical section was 16.968249mm and 18.61464mm. the average error of horizontal section was 4.173203mm and 21.487479mm. and the maximum error of horizontal section was 3.571210mm and 17.13255mm. Also We complemented this apparatus a little and We reexamined a shape demobilization error of 3D Face Automatic Recognition Apparatus again. Accuracy of a shape demobilization was improved a little. From now on We complement accuracy of a shape demobilization in 3D Face Recognition Apparatus.

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Ground State Energy of Gd3+ Paramagnetic Ion in PbWO4 : Gd Single Crystal (PbWO4 : Gd 단결정 내의 Gd3+ 상자성 이온에 대한 바닥 상태 에너지)

  • Yeom, Tae Ho
    • Journal of the Korean Magnetics Society
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    • v.26 no.2
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    • pp.45-49
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    • 2016
  • Ground state energy levels of $Gd^{3+}$ ion (effective spin S = 7/2) in $PbWO_4$ single crystal doped with $Gd^{3+}$ paramagnetic impurity at tetragonal symmetry are calculated with spectroscopic splitting parameters and zero field splitting parameters using by effective spin Hamiltonian. It turns out that the zero field splitting energies of $Gd^{3+}$ ion were the same regardless of the directions of $PbWO_4$ : Gd single crystal. The calculated energy differences for ${\mid{\pm}7/2}$ > ${\leftrightarrow}{\mid{\pm}5/2}$ >, ${\mid{\pm}5/2}$ > ${\leftrightarrow}{\mid{\pm}3/2}$ >, and ${\mid{\pm}3/2}$ > ${\leftrightarrow}{\mid{\pm}1/2}$ > transitions were 6.9574 GHz, 6.9219 GHz, and 15.8704 GHz, respectively when the applied magnetic field is zero. The calculated energy level diagrams were different for different directions of applied magnetic field. For B // a- and c-axis, the energy level diagrams are calculated and discussed.

Characteristics of Black Carbon Particles in Ambient Air Using a Single Particle Soot Photometer (SP2) in May 2013, Jeju, Korea (SP2 (Single Particle Soot Photometer)를 이용한 제주도 5월 Black Carbon 특성)

  • Oh, Jun;Park, Jinsoo;Lee, Sanguk;Ahn, Joonyoung;Choi, Jinsoo;Lee, Sangdeok;Lee, Yonghwan;Kim, Hyunjae;Hong, Youdeog;Hong, Jihyung;Kim, Jeongho;Kim, SangWoo;Lee, Gang-Woong
    • Journal of Korean Society for Atmospheric Environment
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    • v.31 no.3
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    • pp.255-268
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    • 2015
  • Single particle soot photometer (SP2) is an advanced instrument capable of real-time measurement of concentration, coating thickness, and size distribution of individual BC particle using laser-induced incandescence. So far, there have been insufficient studies examining the real-time characteristics of BC in Korea. In this study, we examined temporal variations in BC concentration and mass size distribution of BC in volume equivalence diameter at a background site of Aewol, Jeju in May. Average concentration and mass median diameter (MMD) of BC particles measured during the study period (06~ 16 May 2013) were $0.69{\pm}0.48{\mu}g/m^3$ and $196{\pm}17nm$, respectively. The BC concentration measured in Aewol was very similar to that observed in the spring of 2012 in Baengnyeong island, and showed diurnal profiles similar to those in other background areas. MMD of BC ranged from 172 to 222 nm. It was found that the mass size distribution of BC varied depending on the location (ground-based), season, types of air masses, and altitude (aircraft-based).

Update of Digital Map by using The Terrestrial LiDAR Data and Modified RANSAC (수정된 RANSAC 알고리즘과 지상라이다 데이터를 이용한 수치지도 건물레이어 갱신)

  • Kim, Sang Min;Jung, Jae Hoon;Lee, Jae Bin;Heo, Joon;Hong, Sung Chul;Cho, Hyoung Sig
    • Journal of Korean Society for Geospatial Information Science
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    • v.22 no.4
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    • pp.3-11
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    • 2014
  • Recently, rapid urbanization has necessitated continuous updates in digital map to provide the latest and accurate information for users. However, conventional aerial photogrammetry has some restrictions on periodic updates of small areas due to high cost, and as-built drawing also brings some problems with maintaining quality. Alternatively, this paper proposes a scheme for efficient and accurate update of digital map using point cloud data acquired by Terrestrial Laser Scanner (TLS). Initially, from the whole point cloud data, the building sides are extracted and projected onto a 2D image to trace out the 2D building footprints. In order to register the footprint extractions on the digital map, 2D Affine model is used. For Affine parameter estimation, the centroids of each footprint groups are randomly chosen and matched by means of a modified RANSAC algorithm. Based on proposed algorithm, the experimental results showed that it is possible to renew digital map using building footprint extracted from TLS data.

Redefinition of the Original Benchmark Height using Long-term Tide Observations Analysis and GPS Levelling Methods (장기간 조위관측자료 분석과 GPS 수준측량 수준원점 성과 재정의)

  • Jung, Tae-Jun;Yoon, Hong-Sic;Hwang, Jin-Sang;Lee, Dong-Ha
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.29 no.4
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    • pp.393-403
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    • 2011
  • In this study, we suggested the period of tide observations is proper to calculate the mean sea level(MSL) precisely on Incheon tide station using wavelet analysis, and newly determined then the vertical reference surface of Korea using the calculated MSL. In order to calculate the height difference between the calculated MSL and specific ground station (ICGP) near the Incheon tide stations, we performed the laser measurements directly to the sea surface where located below ICGP. The orthometric-height of ICGP was determined that corrected the height difference to the calculated MSL using linear interpolation method. Finally, we connected the orthometric-height of ICGP with the original benchmark (ORBM) using GPS leveling methods for determining the new orthometric-height of ORBM. As the results, there is a variation amount of 0.026m between the new MSL was calculated in this study and old MSL was calculated in 1910's. Also, there is a difference of 0.035m between the new and old orthometric-heights of ORBM. The connection (or leveling) error of 0.009m was revealed in new orthometric height of ORBM with consideration of MSL variation which may caused by the error of GPS ellipsoid height and/or geoid model. In this study, we could be determined precisely the orthometric-height of ORBM based on the new MSL of Incheon Bay using only GPS leveling method, not a spirit leveling method. Therefore, it is necessary to determine the vertical datum strictly using long-term and continuously tide observations more than 19 years and to use the GPS leveling method widely in the height leveling work for the effective changeover from the orthonormal to the orthometric in national height system.

A Study on the Skin Disease of Sanghanron 《傷寒論》 and Geumgweyoryak 《金匱要略》 (《상한론(傷寒論)》, 《김궤요략(金匱要略)》의 피부증상(皮膚症狀) 및 질환(疾患)에 대한 연구(硏究))

  • Kang, Na-Ru;Han, Jung-Min;Ko, Woo-Shin;Yoon, Hwa-Jung
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.25 no.1
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    • pp.55-74
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    • 2012
  • Objective : The purpose of this study is to investigate the skin disease in Sanghanron"傷寒論" and Geumgweyoryak"金匱要略". Methods : We conducted a study on the original text paragraphs of Sanghanron and Geumgweyoryak containing the skin disease and analysis of Woo, Oh, Sung, Zhang, etc. We drew a parallel between skin disease from Sanghanron and Geumgweyoryak and matching diagnoses from western medicine. Results : The results were as follows. 1. In Sanghanron and Geumgweyoryak pruritus was related to psychogenic pruritus and similar to skin disease caused by decrease of sweating, dry skin in cholinergic urticaria, atopic dermatitis and eczema, etc. in western medicine. 2. In Geumgweyoryak ichthyosis was caused by woman's disease, after menopause, chronic disease and malnutrition and related to winter itch and xerotic eczema in western medicine. 3. In Sanghanron Goose bumps, keratosis follicularis, acute and chronic urticaria and cold urticaria were occurred because of poorly managed fever care and side effect of antibiotic. 4. In Geumgweyoryak red face was similar to face flushing and side effects, which is after drug and laser treatment on face, in western medicine. 5. In Geumgweyoryak urticaria was, in a broad sense, skin disease with pruritus and secondary infection resulted from scratch. Skin diseases with pruritus are similar to urticaria, dermatitis herpetiformis, lichen planus, atopic dermatitis, contact dermatitis, psoriasis, nummular eczema, lichen simplex chronicus, prurigo nodularis, neurodermatitis and internal disease with pruritus in western medicine. 6. In Geumgweyoryak spots in the skin were caused by fever and similar to allergic purpura and SLE symptom in western medicine. 7. In Geumgweyoryak bullous disease with yellowish discharge was similar to eczema, pustule, atopic eczema, etc. in western medicine. 8. In Geumgweyoryak repeated inflammation of oral cavity, genitals, eyes and skin was similar to Behcet's disease in western medicine. 9. In Sanghanron and Geumgweyoryak boil was similar to abscess and acute lymphadenitis in western medicine caused by oily foods and infections. 10. In Geumgweyoryak swelling and boil were occurred in a poor health. Damage from metalic material could cause a convulsion and was similar to tetanus in western medicine. Conclusion : We analyzed the original text paragraphs of Sanghanron and Geumgweyoryak and explanations about skin disease. As a results, we found out etiology, pathogenesis, treatments of the skin disease in Sanghanron and Geumgweyoryak. Further we compared with western medicine to develop better understanding of the skin disease.

Three-dimensional Assessment of Facial Soft Tissue after Orthognathic Surgery in Patients with Skeletal Class III and Asymmetry

  • Lee, Jong-Hyeon;Choi, Dong-Soon;Cha, Bong-Kuen;Park, Young-Wook;Jang, Insan
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.35 no.6
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    • pp.360-367
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    • 2013
  • Purpose: The purpose of this study was to perform three-dimensional (3D) assessment of facial soft tissue in patients with skeletal Class III and mandibular asymmetry after orthognathic surgery. Methods: Samples consisted of 3D facial images obtained from five patients with A point-nasion-B point angle less than 2 degrees, and more than 5 mm of menton deviation. All patients had been treated at Gangneung-Wonju National University Dental Hospital from 2009 to 2012. They had undergone orthognathic surgery of Lefort I, and sagittal split osteotomy for correction of skeletal deformity, and orthodontic treatment. Facial scanning was performed before treatment (T1) and post-surgical orthodontic treatment (T2). Linear and angle variables of soft tissue landmarks, antero-posterior facial depth, and facial volume were measured. Results: No significant differences in width of the alar base, mouth width, and nasal canting were observed between T1 and T2. However, lip deviation, menton deviation, alar canting, lip canting, and menton deviation angle were significantly reduced at T2. Antero-posterior facial depth on the axial plane parallel to the left cheilion was significantly reduced on the deviated side and significantly increased on the non-deviated side at T2. Volume of the lower lateral and lower medial parts of the face was reduced on the deviated side, and volume of upper lateral and lower lateral parts on the non-deviated side was significantly increased at T2. Conclusion: After orthognathic surgery, facial asymmetry of soft tissue was improved following skeletal changes, especially the mandibular region. Although the length of the alar base and mouth width did not change, lip and soft tissue menton were displaced to the medial side after treatment. Facial depth also became symmetric after treatment. Facial volume showed a decrease on the lower part of the deviated side and that on lateral parts of the non-deviated side showed an increase after treatment.

Calibration System for Angular Vibration Using Precision Rotary Encoder (고정밀 회전엔코더를 이용한 회전진동 교정시스템)

  • Nam, Seunghwan;Baik, Kyungmin;Cheung, Wan-Sup
    • The Journal of the Acoustical Society of Korea
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    • v.33 no.1
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    • pp.31-39
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    • 2014
  • In this paper, two calibration methods for angular vibration pickups using a precision rotary encoder are proposed. The KRISS (Korea Research Institute of Standards and Science) primary angular vibration calibration system and the calibration procedures are briefly explained. The rotary encoder is shown to be calibrated in two methods: The one is to use the laser interferometer to calibrate the rotary encoder under test and the other is to exploit the certificate of the encoder supplied. Complex sensitivities measured from the first are shown to be less than 0.1 % difference in magnitude and $0.01^{\circ}$ difference in phase shift in reference to those of the primary calibration system. Their expanded uncertainties were observed to be less than 0.6 % in magnitude and $0.4^{\circ}$ in phase shift over the range of 0.4 to 200 Hz. Under the same calibration conditions, complex sensitivities evaluated by the second method are shown be 0.1 % difference in magnitude and $0.6^{\circ}$ difference in phase shift in reference to those of the primary calibration system. Their expanded uncertainties were seen to be less than 4.8 % in magnitude and $2.8^{\circ}$ in phase shift.

A Study on the Selection and Applicability Analysis of 3D Terrain Modeling Sensor for Intelligent Excavation Robot (지능형 굴삭 로봇의 개발을 위한 로컬영역 3차원 모델링 센서 선정 및 현장 적용성 분석에 관한 연구)

  • Yoo, Hyun-Seok;Kwon, Soon-Wook;Kim, Young-Suk
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.33 no.6
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    • pp.2551-2562
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    • 2013
  • Since 2006, an Intelligent Excavation Robot which automatically performs the earth-work without operator has been developed in Korea. The technologies for automatically recognizing the terrain of work environment and detecting the objects such as obstacles or dump trucks are essential for its work quality and safety. In several countries, terrestrial 3D laser scanner and stereo vision camera have been used to model the local area around workspace of the automated construction equipment. However, these attempts have some problems that require high cost to make the sensor system or long processing time to eliminate the noise from 3D model outcome. The objectives of this study are to analyze the advantages of the existing 3D modeling sensors and to examine the applicability for practical use by using Analytic Hierarchical Process(AHP). In this study, 3D modeling quality and accuracy of modeling sensors were tested at the real earth-work environment.