• 한국환경복원기술학회지
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• 제16권4호
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• pp.83-97
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• 2013

The traditional village forests in Korea such as Dangsan forests and Bibo forests form unique cultural landscape and they are national cultural assets with histories of more than several hundred years. It is important to have sustainable right to enjoy cultural heritage as well as maintaining its authenticity. Cultural assets are meaningful only when they are managed to succeed to next generations. Dangsan forests and Bibo forests need to be named properly and recognized by society as a precious cultural heritage for many generations to come in order to claim the value as traditional cultural landscapes in Korea. The traditional village forest in Dangin-ri, Wando-gun was composed of a Dangsan forest and five Bibo forests. Although this traditional village forest is large in size, it was not on the report of Cultural Heritage Administration(2005) investigated for 'Village forest of island region in Jeollanam-do'. The objective of this study was to investigate the characteristics of the traditional village forest in Dangin-ri to grant correct name and to enhance its value. In this study the characteristics of a Dangsan forest and five Bibo forests were investigated from 2006 to 2013 for physical features such as size, shape, location, tree species composition, and diameter at breast height(DBH), as well as cultural aspects and tradition. Currently the naming and designation of natural monuments by the cultural heritage administration(CHA) is based on the rule enacted in 1934. Many Dangsan forests were named as evergreen forests. This type of names does not represent the meaning of traditional village forest. It was suggested that this traditional village forest is to be named as 'Dangsan Forest and Bibo Forests at Dangin-ri, Wando-gun'. This traditional village forest needs to reclaim authenticity and rebuild its original appearance by restoration of the disturbed areas, especially in Bibo forest I.

• 한국환경과학회지
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• 제19권4호
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• pp.415-425
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• 2010

The purpose of the present study was to analyze the vegetation structure and distributional characteristics of Abies koreana forests in Mt. Halla, and to provide basicdata for an ecological study on Abies koreana in Mt. Halla. The results of the analysis showed that the mean importance percentage(M.I.P,) of Abies koreana in the Youngsil and Bangaeoreum and the Azalea field were 28.3%, 23.6%, and 46.4%, respectively. The ratios of DBH (diameter at breast height) to height were similar in all region, except in the Azalea field, where Abies koreana of various ages, both young and old, were found. The species diversity (H) of the upper and lower layers in the Youngsil and Bangaeoreum and in the Azalea field were 0.625 and 0.810, 0.731 and 0.848, and 0.342 and 0.757, respectively. A total of 52 community were distributed at locations higher than 1,300m above sea level. The proportions of each community in the whole Abies koreana forest were 56.5%(Azalea field), 11.0% (Youngsil trail at 1,550-1,650 m above sea level), and 8.1%(Janggumok and Kundurewat region). The total area of the Abies koreana forest was calculated to be 795.3ha by combining all the areas of each community. An Abies koreana forest with the largest area was found at locations 1,500-1,600 m above sea level, taking up 38.8% of the total Abies koreana forest area. For the slopes of the distributional area of Abies koreana, 46.1%(highest proportion) of the total area was $10\sim25^{\circ}$, and for the azimuth of the distributional area, 17.4%(the highest proportion) of the total area was $0-45^{\circ}$. The vegetation structure showed large differences between areas. It was found, however, that the distribution was mostly in the areas with a relatively gentle slope. It is suggested that research be done to forecast the possible changes in the differences in the vegetation structures between different areas caused by climate changes. In addition, there is a need to monitor the Abies koreana and alpine plants in the subalpine zones of Mt. Halla, which are sensitive to climate change, to obtain the basic data that are necessary for the protection and maintenance of the ecosystem.

• Asian-Australasian Journal of Animal Sciences
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• 제15권12호
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• pp.1760-1764
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• 2002

In order to elucidate the physiological function of circulating IGF-I on muscle protein synthesis in the chicken under malnutritional conditions, we administrated recombinant chicken IGF-I using a osmotic mini pump to fasted young chickens and measured the rate of muscle protein synthesis and plasma metabolite. The pumps delivered IGF-I at the rate of $22{\mu}g/d\{300{\mu}g{\cdot}(kg\;body\;weight{\cdot}d)^{-1}\}$. Fractional rate of protein synthesis in the muscle was measured using a large dose injection of L-[$2,6-^3H$]phenylalanine. Constant infusion of chicken IGF-I did not affect plasma glucose level. Significant interaction between dietary treatment and IGF-I infusion was observed in plasma NEFA and total cholesterol concentrations. When chicks were fasted, IGF-I infusion decreased plasma NEFA and total cholesterol concentrations. On the other hand, IGF-I administration did not affect plasma levels of both metabolites. Fasting reduced plasma triglyceride concentration significantly. IGF-I infusion also decreased the level of plasma triglyceride. Plasma IGF-I concentration of young chickens was halved by fasting for 1 d. IGF-I infusion using an osmotic minipump for 1 d increased plasma IGF-I concentration in fasted chicks to the level of fed chicks. Fasting decreased body weight and the loss of body weight was significantly ameliorated by IGF-I infusion. There was a significant interaction between dietary treatment and IGF-I infusion in the fractional rate of breast muscle protein synthesis. There was no effect of IGF-I infusion on muscle protein synthesis in fed chicks. Muscle protein synthesis reduced by fasting was ameliorated by IGF-I infusion, but did not reach to the level of fed control. Muscle weight of fasted chicks infused with IGF-I was similar to fasted birds without IGF-I infusion, which suggests that muscle protein degradation would be increased by IGF-I infusion as well as protein synthesis in fasted chicks.

• Asian Pacific Journal of Cancer Prevention
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• 제16권4호
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• pp.1449-1453
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• 2015

Background: Oral capecitabine is increasingly replacing intravenous 5-fluorouracil in many chemotherapy regimens. However, data on the risk of febrile neutropaenia (FN) and treatment related death (TRD) with the drug remain sparse outside of clinical trial settings despite its widespread usage. This study aimed to determine these rates in a large cohort of patients treated in the University of Malaya Medical Centre (UMMC). Materials and Methods: We reviewed the clinical notes of all patients prescribed with oral capecitabine chemotherapy for any tumour sites in University Malaya Medical Centre (UMMC) from $1^{st}$ January 2009 till $31^{st}$ June 2010. Information collected included patient demographics, histopathological features, treatment received including the different chemotherapy regimens and intent of treatment whether the chemotherapy was given for neoadjuvant, concurrent with radiation, adjuvant or palliative intent. The aim of this study is to establish the pattern of usage, FN and TRD rates with capecitabine in clinical practice outside of clinical trial setting. FN is defined as an oral temperature > $38.5^{\circ}C$ or two consecutive readings of > $38.0^{\circ}C$ for 2 hours and an absolute neutrophil count < $0.5{\times}10^9/L$, or expected to fall below $0.5{\times}10^9/L$ (de Naurois et al., 2010). Treatment related death was defined as death occurring during or within 30 days of last chemotherapy treatment. Results: Between $1^{st}$ January 2009 and $30^{th}$ June 2010, 274 patients were treated with capecitabine chemotherapy in UMMC. The mean age was 58 years (range 22 to 82 years). Capecitabine was used in 14 different tumour sites with the colorectal site predominating with a total of 128 cases (46.7%), followed by breast cancer (35.8%). Capecitabine was most commonly used in the palliative setting accounting for 63.9% of the cases, followed by the adjuvant setting (19.7%). The most common regimen was single agent capecitabine with 129 cases (47.1%). The other common regimens were XELOX (21.5%) and ECX (10.2%). The main result of this study showed an overall FN rate of 2.2% (6/274). The overall TRD rate was 5.1% (14/274). The FN rate for the single agent capecitabine regimen was 1.6% (2/129) and the TRD rate was 5.4% (7/129). All the TRDs were with single agent capecitabine regimen were used for palliative intent. Conclusions: Oral capecitabine is used widely in clinical practice in a myriad of tumour sites and bears a low risk of febrile neutropaenia. However, capecitabine like any other intravenous chemotherapeutic agent carries a significant risk of treatment related death.

• 대한방사성의약품학회지
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• 제1권1호
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• pp.38-45
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• 2015

Most tumors are believed to overexpress several receptors, and small peptides targeting these receptors were developed for diagnosis and tumor therapy during past decade. Here we report that fibroadenoma can be visualized by bladder cancer specific peptide. A 9-mer bladder cancer specific peptide, which was discovered from the phage display method, was synthesized by peptide synthesizer, and additional tyrosine was conjugated at the N-terminal for radioiodination (Y-BP). Y-BP was radiolabeled with $^{131/124}I$ using Iodogen tube. The rat treated with N-butyl-N-(4-hydroxybutyl)nitrosamine for 8 weeks was allowed to grow until large size tumor was developed under axilla. The tumor model was microPET imaged sequentially using [$^{18}F$]FDG and radioiodinated $^{124}I-Y-BP$. The tumor was excised and examined by immunostaining studies. Radioiodinated $^{124}I-Y-BP$ was purified using fast protein liquid chromatography (FPLC) in > 90% radiochemical purity. The whole tumor was well visualized by [$^{18}F$]FDG with several intense focal uptake within tumor. The tumor was also clearly seen with $^{124}I-Y-BP$ at 4 h post-injection, and to our surprise the tumor uptake of $^{124}I-Y-BP$ lasted up to three days. The tumor was diagnosed histologically as a fibroadenoma derived from mammary gland. In conclusion, the bladder cancer specific peptide showed the good potential as a new radiotracer for the detection of breast fibroadenoma.

• 한국축산식품학회지
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• 제28권2호
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• pp.240-245
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• 2008

본 연구에서는 식품 내에 존재하는 트랜스지방산 함량에 대한 기초 자료를 수집하기 위하여 서울 지역에서 수거한 레토르트식품류 2종, 분유류 6종, 비스킷류 7종 피자류 3종을 선택하여 총 4종류의 18종의 시료를 분석하였다. 레토르트식품류 2종, 분유류 6종, 비스킷류 1종은 chloroform-methanol(CM) 추출법에 의하여 조지방을 추출하였으며 비스킷류 6종, 피자류 3종은 chloroform-methanol(CM) 추출법과 acid digestion 추출법을 각각 이용하여 조지방을 추출한 후 gas chromatography(GC)에 의해 트랜스지방산 함량을 분석하였다. 레토르트식품류의 총 지방 중 트랜스지방산 함량은 1-2.8%이며 분유류의 트랜스지방산 함량은 0.4-2.4%로서 제품의 브랜드와 제조회사에 따라 차이가 많이 났다. 비스킷류의 트랜스지방산 함량은 0-2.95%로서 제품 간 가장 많은 차이를 나타내었으며 이는 첨가물의 종류에 따라 달라지는 것으로 사료된다. 피자류에서는 2.8-3.45%의 높은 트랜스지방산 함유율을 나타내었다.

• 한국동물위생학회지
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• 제31권1호
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• pp.161-166
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• 2008

Deep pectoral myopathy (DPM), also known as Oregon muscle disease or green muscle disease, was first described in 1968 by Dickinson et al as "degenerative myopathy" in turkeys. Even though this condition was first recognized in adult meat-type turkey and chicken breeders, it is becoming more and more common in meat-type growing birds. DPM occurs exclusively in birds that have been specially selected for breast muscle development. It is generally recognized that DPM is an ischemic necrosis that develops in the deep pectoral muscle (supracoracoideus or pectoralis minor muscle) mainly because this muscle is surrounded by inelastic fascia and the sternum, which do not allow the muscle mass to swell in response to the physiological changes occurring when muscle are exercised, as in wing flapping. The lesion does not impair the general health of birds and is generally found during cut-up and deboning, moreover, it can be both unilateral or bilateral, affecting just one or both pectoralis minor muscle, respectively. No public health significance is associated to DPM, but it is aesthetically undesirable. The fillet should be removed, whereas the rest of the carcass is still fit for human consumption. However, the required trimming operations determine the downgrading of the products and produce an economic loss for the industry, especially because it affects the more valuable part of the carcass. The incidence of DPM increases with market weight in broilers, with more cases reported in higher-yielding strains and in males. Increased bird activity (flock nervousness, flightiness, struggle, and wing flapping) induced by factors such as feed or water outages, lighting programs and intensity, human activity, and excessive noises in and around chicken houses should be looked at as a trigger for the development of DPM in broiler. However, most of the studies conducted to evaluate the incidence of DPM in poultry are concerned with parental commercial breeding stocks under experimental conditions (Bianchi et al. 2006. Poult Sci 85 : 1843-1846). There is a possible genetic relationship between the selection for large-breasted birds and this condition. Management procedures that discourage excessive wing flapping would reduce the incidence (Jordan and Pattison. 1998. Poultry diseases. 398-399).

• 대한소아치과학회지
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• 제41권3호
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• pp.247-256
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• 2014

이 연구의 목적은 대전지역 미취학 어린이의 비수유성 빨기 습관의 유병률을 조사하고 이 유병률에 영향을 미치는 기여요인과의 관련성을 평가하며 비수유성 빨기 습관이 유치열의 교합에 어떤 영향을 주는지 알아보고자 하는 것이다. 구강검진을 위해 개인치과에 내원한 만 18개월에서 65개월 사이의 어린이 841명을 검사하고 그 보호자를 대상으로 설문조사를 시행하였다. 전체 설문에 대답한 어린이 중 32.8%에서 비수유성 빨기 습관이 있었으며 여아에서 37.7%로 남아보다 유의하게 더 높았다. 모유 수유의 기간이 길어짐에 따라 비수유성 빨기 습관 유병률은 유의한 감소를 보였으며 출생순서와 엄마의 직업유무는 관련성이 없었다. 손가락빨기가 전체 비수유성 빨기 습관 어린이 중 62.6%로 인공젖꼭지빨기(37.4%)에 비해 더 우세하였고 습관의 지속기간 또한 유의하게 길었다. 비수유성 빨기 습관의 지속기간이 길어질수록 유치열 교합이상이 더 많이 관찰되었다.

• 한국의류학회지
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• 제27권3_4호
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• pp.407-417
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• 2003

The purpose of this study is to develop designs and patterns of a functional brassiere. For this purpose, women who have protruding and drooping breasts with 75B for their brassiere size were sampled. The fitting test for the fitness and function of test brassiere and control brassiere were carried out twice and compared the results from the both in terms of front, rear and side looks. The results of this study can be summarized as follows; 1. The results from measuring the level of sag and spread, and volume and protrusion of breasts shows that there are some distinctive differences in the measurements before and after wearing the test brassiere and the test brassiere is proved to be very effective in correcting breasts' shapes. 2. Front look: Since the two front cutting lines of the test brassiere served to have the curved main part pressing against the breasts, it could support breasts to more than satisfactory level. In addition, upperline panel and side panels of the test brassiere were found to have the upperline of the upper cup pressed against the breasts and at the same time it pressed and gathered the flab around upper part of the breasts and armpits that helped to rearrange the shape of the breasts. It is also proved that the two-pieced test brassier was found to be more functional in supporting the lower cup of the breasts. 3. Rear look: The test brassier was made up of two wide U-shaped wings with 2.5cm tape on its lower sides. Each wing has 4 lines and 3 hems (5.5cm). For this reason, the test brassiere was tighter and better fitted on its back. 4. Side look and entire look: The wings of the test brassiere might look wider than that of the control brassier which has conventional straight-shaped wings, but it was analyzed that the test brassiere held the upper and lower sides of the wings more effectively to be more pressed against the breast. Therefore, the test brassiere scored higher in terms of adjusting to body movements, while the control brassiere looked better in overall terms. 5. The functional brassier fur protruding and drooping breasts developed from the experiments of this study is a full side stretch brassiere which covers the entire breasts satisfactorily. The pattern drafting methods are suggested in to .

• 한국정보통신학회논문지
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• 제22권10호
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• pp.1277-1286
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• 2018

본 논문에서는 공개의료정보 빅데이터 분석을 위해 클라우드 환경에서 아파치 하둡 기반의 클라우드 환경을 도입하여 컴퓨팅 자원의 유연한 확장성을 제공하고 실제로, 로그데이터가 장기간 축적되거나 급격하게 증가하는 상황에서 스토리지, 메모리 등의 자원을 신속성 있고 유연하게 확장을 할 수 있는 기능을 포함했다. 또한, 축적된 비정형 로그데이터의 실시간 분석이 요구되어질 때 기존의 분석도구의 처리한계를 극복하기 위해 본 시스템은 하둡 (Hadoop) 기반의 분석모듈을 도입함으로써 대용량의 로그데이터를 빠르고 신뢰성 있게 병렬 분산 처리할 수 있는 기능을 제공한다. 빅데이터 분석을 위해 빈도분석과 카이제곱검정을 수행하고 유의 수준 0.05를 기준으로 단변량 로지스틱 회귀분석과 모델별 의미 있는 변수들의 다변량 로지스틱 회귀분석을 시행 하였다. (p<0.05) 의미 있는 변수들을 모델별로 나누어 다변량 로지스틱 회귀 분석한 결과 Model 3으로 갈수록 적합도가 높아졌다.