• Safety and Health at Work
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• 제7권4호
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• pp.299-306
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• 2016

Background: Noncompliance of operators with work procedures is a recurrent problem. This human behavior has been said to be situational and studied by many different approaches (ergonomic and others), which consider the noncompliance with work procedures to be obvious and seek to analyze its causes as well as consequences. Methods: The object of the proposed method is to solve this problem by focusing on the performance of work procedures and ensuring improved performance on a continuous basis. Results: This study has multiple results: (1) assessment of the work procedures' performance by a multicriteria approach; (2) the use of a continuous improvement approach as a framework for the sustainability of the assessment method of work procedures' performance; and (3) adaptation of the Stop-Card as a facilitator support for continuous improvement of work procedures. Conclusion: The proposed method emphasizes to put in value the inputs of continuous improvement of the work procedures in relation with the conventional approaches which adopt the obvious evidence of the noncompliance to the working procedures and seek to analyze the cause-effect relationships related to this unacceptable phenomenon, especially in strategic industry.

• 한국가스학회지
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• 제16권5호
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• pp.21-27
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• 2012

대학 실험실이나 연구시설에서 실험실 사고에 의해 인적 및 물적 손실이 꾸준히 발생되고 있어서 실험실 사고예방의 필요성이 제기되고 있다. 실험실 사고예방을 위해 무엇보다 중요한 것은 사고의 체계적인 분석이다. 국내에서 산업재해에 관한 분석 연구는 수행되어 왔으나, 실험실 사고 분석에 관한 연구는 수행되지 않았다. 본 연구에서는 실험실 사고예방 대책 수립을 위해 설문지를 개발하였고, 설문지는 대학과 연구기관에 전자우편이나 방문조사로 사고사례를 수집하였다. 사고사례 데이터는 계절별, 사고 분류형태, 발생형태, 기인물 및 상해종류 별로 분석 고찰하였다. 이 연구결과는 실험실 종사자의 안전 확보와 사고예방을 위한 기초자료로 활용하고자 하였다.

• Safety and Health at Work
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• 제13권1호
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• pp.86-92
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• 2022

Background: A laboratory where chemicals are handled can be considered a hazardous environment, and hence, prudent practices should be strictly enforced. If not, deadly accidents and incidents could occur due to a lack of safety practices and poor safety culture. The purpose of this study is to analyze the existing safety culture and propose potential recommendations to enhance the level of safety education in the chemical laboratories in the Western Province of Sri Lanka. Methods: A survey questionnaire was administered among the laboratory supervisors of the chemical laboratories in the Western Province of Sri Lanka in 2019. Results: Even though 80 surveys were distributed among prospective participants, only 46 surveys were submitted, which is 58% of the response rate. Most of the individuals who participated in the survey were females below 35 years old, and approximately 96% of the participants had at least one year of working experience in the same laboratory setting. The majority considered safety as an important factor that requires further improvements with third-party safety inspections; however, 54% of the respondents mentioned that those inspections were conducted by the employees from their laboratory. Conclusion: From the study, it has been discovered that employees have knowledge of safety culture to a certain extent. A significant percentage (83%) of participants believed that further safety measures are required for a safer laboratory. However, the study revealed that the attitudes of some employees should be changed to have a better safety culture. Hence the authors would like to suggest having annual training sessions and well-formulated safety policies to improve the safety culture.

• 웰빙융합연구
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• 제6권3호
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• pp.25-32
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• 2023

Purpose: This study is to improve awareness of MSDS in order to prevent university accidents and protect university laboratory workers. In order to improve awareness, measures to increase accessibility through auxiliary means (warning signs, One Page Sheet MSDS, etc) and ways to strengthen safety training (improvement and strengthen MSDS training). Research design, data and methodology: A questionnaire survey was adopted as a research method for this study. Question items were selected, modified, and supplemented by referring to the previous paper. Results: As a result of the survey, MSDS found that it was difficult to find the information they wanted and that there were many technical terms and limitations in using it. In addition, MSDS training is underway, but few university laboratory workers felt that training was helping. This shows that the effectiveness of training is virtually insignificant. Therefore, it seems that improvement measures are needed to solve this. Conclusions: One Sheet MSDS, an effective way for university laboratory workers to communicate information, and MSDS information should be provided with warning signs with large phrases and good visibility. In addition, this study proposes a One Sheet MSDS that prioritizes important MSDS items over all items in the MSDS, and in the field of education, several improvements are proposed, such as "To prevent problems and answers from being shared on the Internet" and "To improve the difficulty of checking the online curriculum".

• Safety and Health at Work
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• 제9권4호
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• pp.473-478
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• 2018

Background: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of volatile chemical. University researchers in chemical laboratories suffer a phenomenon of multi-exposition to chemical agents at low concentration during long periods of time although in an irregular form. Many of these chemical agents have similar properties to those suspicious of causing MCS. This article studies the prevalence of MCS in laboratory researchers. Methods: The study group is university researchers in chemical laboratories. The control group was obtained from administrative personnel who work in the same universities and therefore, are not exposed to chemical products from the laboratories, but have the same exposition to the rest of environmental polluting agents from the area and from the buildings of the university. In this study, it is used the Quick Environmental Exposure and Sensitivity Inventory (QEESI) (sensitivity of 92%/specificity of 95%). Results: The results showed that the prevalence of MCS for the university researchers is not related to exposition by inhalation to multiple chemical agents, at low concentration. Conclusions: The results disagree with one of the main etiological hypotheses of MCS, which is based on the existence of hypersensitive people, who presents a response after prolonged expositions to very low concentrations during a long period of time.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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• pp.135-135
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• 2002

Nowadays a huge variety of products that aim to assist to quit smoking or reduce addictive symptoms are developed and manufactured with safety evaluation, but the safety of the most recent products of interest which do not contain tobacco and nicotine, and shape cigarettes is not evaluated and guaranteed relatively.(omitted)

• 한국가스학회지
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• 제16권2호
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• pp.60-66
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• 2012

연구개발 활동의 다양화와 융합화에 따라 실험실에서 다양한 종류의 화학물질의 취급 사용과 함께 실험실의 수행업무도 복잡 다양해져 잠재위험이 크다. 또한, 실험조건이 극한의 온도와 압력 하에서 수행되는 경우가 많아 화재폭발 사고 등으로 인명 피해가 발생하고 있다. 본 연구에서는 대학과 연구기관의 실험실에서 화학물질 사용현황과 특성을 파악하여 실험종사자들의 안전성 확보를 위한 조사 도구로서 실험실 설문지를 개발하였다. 개발된 설문지를 이용하여 연구기관과 대학을 대상으로 전자우편과 방문조사로 화학물질 사용량과 폐기량 및 실험실 환경에 대한 인식도 조사를 실시하였다. 수집된 설문지 자료는 엑셀로 빈도 분석을 하여 실험실 사고예방 대책수립을 위한 기초 자료로 활용하고자 한다.

• Toxicological Research
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• 제12권1호
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• pp.113-119
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• 1996

Group of 40 male and 40 female Sprague-Dawley rats was given daily intravenous injections of different dosage of Ginkgo biloba extract(EGb 761), 7.5 mg/kg/day (low dosage group), 15 mg/kg/day (middle dosage group), or 30 mg/kg/day (high dosage group)for 3 month by tail vein according to Established Regulation of Korean National Institute of Safety Research (1994. 4. 14). Appearance, behavior, mortality, and food consumption of rats of treated groups were not affected during the experimental periods. No significant Ginkgo biloba extract(EGb 761)-related changes were found in urinalysis, hematology, serum chemistry, and organ weight. No histopathological lesions were seen in both control and treatment groups. Our results strongly suggest that no toxic changes were found in rat treated intravenously with Ginkgo biloba extract(EGb 761)for 3 month.

• Toxicological Research
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• 제31권2호
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• pp.157-163
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• 2015

Nanotechnology has advanced at an extremely rapid pace over the past several years in numerous fields of research. However, the uptake of nanoparticles (NPs) into the body after administration through various routes may pose a risk to human health. In this study, we investigated the potential ocular toxicity of 20-nm, negatively- charged zinc oxide (ZnO) NPs in rats using micro-computed tomography (micro-CT) and histopathological assessment. Animals were divided into four groups as control group, ZnO NPs treatment group (500 mg/kg/day), control recovery group, and ZnO NPs treatment and recovery group. Ocular samples were prepared from animals treated for 90 days (10 males and 10 females, respectively) and from recovery animals (5 males and 5 females, respectively) sacrificed at 14 days after final treatment and were compared to age-matched control animals. Micro-CT analyses represented the deposition and distribution of foreign materials in the eyes of rats treated with ZnO NPs, whereas control animals showed no such findings. X-ray fluorescence spectrometry and energy dispersive spectrometry showed the intraocular foreign materials as zinc in treated rats, whereas control animals showed no zinc signal. Histopathological examination revealed the retinopathy in the eyes of rats treated with ZnO NPs. Neuronal nuclei expression was decreased in neurons of the ganglion cell layer of animals treated with ZnO NPs compared to the control group. Taken together, treatment with 20-nm, negatively-charged ZnO NPs increased retinopathy, associated with local distribution of them in ocular lesions.

• Asian-Australasian Journal of Animal Sciences
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• 제33권12호
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• pp.2008-2020
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• 2020

Objective: This study was conducted to investigate the effects of dietary corn resistant starch (RS) on the intestinal morphology and barrier functions of broilers. Methods: A total of 320 one-day-old broilers were randomly allocated to 5 dietary treatments: one normal corn-soybean (NC) diet, one corn-soybean-based diet supplementation with 20% corn starch (CS), and 3 corn-soybean-based diets supplementation with 4%, 8%, and 12% corn resistant starch (RS) (identified as 4% RS, 8% RS, and 12% RS, respectively). Each group had eight replicates with eight broilers per replicate. After 21 days feeding, one bird with a body weight (BW) close to the average BW of their replicate was selected and slaughtered. The samples of duodenum, jejunum, ileum, caecum digesta, and blood were collected. Results: Birds fed 4% RS, 8% RS and 12% RS diets showed lower feed intake, BW gain, jejunal villus height (VH), duodenal crypt depth (CD), jejunal VH/CD ratio, duodenal goblet cell density as well as mucin1 mRNA expressions compared to the NC group, but showed higher concentrations of cecal acetic acid and butyric acid, percentage of jejunal proliferating cell nuclear antigen-positive cells and delta like canonical Notch ligand 4 (Dll4), and hes family bHLH transcription factor 1 mRNA expressions. However, there were no differences on the plasma diamine oxidase activity and D-lactic acid concentration among all groups. Conclusion: These findings suggested that RS could suppress intestinal morphology and barrier functions by activating Notch pathway and inhibiting the development of goblet cells, resulting in decreased mucins and tight junction mRNA expression.