• The Korean Journal of Archival Studies
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• no.42
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• pp.37-71
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• 2014

The purpose of this study was to analyze developed case of archiving on Mega Sport Event for searching effective method on a documentation of Mega Sport Event. In order to conduct this study, literature review method was using about book, thesis and data of internet homepage for exploring the stage on Mega Sports Event and case of Mega Sports Event record management. The field study was conducted about institute related to Olympic record management institution for analysing Mega Sports Event record management. The result of this study is following: Firstly, 2012London Organizing Committee of the Olympic Games's case(The People's Record Project) is useful to ex-ante event phase. Secondly, 2000Sydney Organizing Committee of the Olympic Games's case(Olympic Games Knowledge Management Project) is useful to event operation phase. Thirdly. LA84Foundation's case(Olympic Oral History Project) is useful to ex-post event. The significance of this study which came up with the study result above can be presented as follows. Based on the result of this study, it is assumed that three case for documentation about Mega Sports Event. Lastly, the result of this study was useful to Mega Sports Event record management institution. For the more, it will be conducted to study law of Mega Sport Event record management, humane and Material resource and method related to record management of the Mega Sports Event organizing committee.

• Food Engineering Progress
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• v.21 no.3
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• pp.249-255
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• 2017

Caesalpinia sappan L. is an oriental medicinal plant distributed in the Asia Pacific region including India, Malaysia, and China. The dried heartwood of Caesalpinia sappan has been traditionally used as an analgesic and anti-inflammatory drug. In this study, the effects of extract methods of C. sappan on contents of total polyphenols and flavonoids, antioxidant activity, and cytotoxic activity were evaluated. As a result, hot water extract from C. sappan (CSWE) significantly exhibited contents of total polyphenols and flavonoids (22.6 mg GAE/g and 14.5 mg QE/g) higher than 70% ethanol extract (CSEE) (17.6 mg GAE/g and 13.2 mg QE/g). However, CSEE showed greater antioxidant activity than CSWE in both DPPH and ABTS. Also, the cytotoxicity of C. sappan against three kinds of cancer cell lines was higher in CSEE than in CSWE. These results show that ethanol extract is a better extract method than hot water method to maintain antioxidant and anti-cancer activities.

• Journal of Korean Society of Neurocognitive Rehabilitation
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• v.10 no.2
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• pp.9-18
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• 2018

The research has sought to examine the effect of cognition training using smart device application games on the cognition function of traumatic brain injury patients. The research was conducted to the seventeen traumatic brain injury patients with slight symptoms who were treated with occupational therapy. The patients were divided into the two groups, nine for the experimental group and eight for the control group. The experimental group was assigned to conduct cognition training using smart device application games and traditional cognition training for fifteen minutes each, and the control group has conducted the traditional cognition training for 30 minutes. All arbitrations were conducted for 30 minutes a day, five times a week and for four weeks. To assess the cognitive function, Korean Mini-Mental State Examination (K-MMSE), Lowenstein Occupational Therapy Cognitive Assessment (LOTCA) and visual memory 1 and 2 of Motor-free Visual Perception Test-3 (MVPT-3) were measured before and after the intervention. In the comparison of the change between the two groups, the experimental groups showed a significant improvement in the visual memory of Motor-free Visual Perception Test-3 and remembrance section of the Korean Mini-Mental State Examination (p<.05). The result of this research has confirmed that the cognition training using the smart device application game can make the positive change to the visual memory of the traumatic brain injury patients more than the traditional cognition training.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.29 no.3
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• pp.12-21
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• 2011

We investigated the location and surveillance system of fortress using inter-visibility analysis between fortress and the capital of the Silla Dynasty. The digital terrain model(DTM) was generated with $10{\times}10m$ grid in Arcview 3.2. Then three fortresses lines(Myeonghwal-sanseong, Namsan-shinseong, Seohyeong-sanseong) were superimposed on the DTM. 4 results of this study were drew out from the cumulative visibility analysis. First, the most of fortress lines which showed the high visible frequency from the Sila-Capital(538 viewpoints) have a good aspect toward the capital. It means that 3 fortresses secured the visibility to the capital. Second, the cumulative visibility analysis from 3 fortresses generated evenly distributed visible frequency across the inside of fortress. It shows that the inner area of fortress is more advantageous to command during the war. On the contrary, a number of invisible(vulnerable) regions which is scattered on the outside were supplemented by adjacent fortress. Third, the north area of the Sila-captial showed the highest visible frequency generated by sum up the visibility from 3 fortresses. The northern captial is placed within 4km distance easy to support at the Myeonghwal and Seohyeong-sanseong. We proved that the Sila-capital had organized a solid surveillance system by 3 fortresses. Fourth, we could infer the practical process of fortress layout from comparing a cumulative visibility map. For the secure of visibility and defense systems, the fortress line would form a rising shape to the peak. This practical location theory can replace the vague common location theory that the fortress would constructed on two thirds of mountain height. It will be an empirical method in the ancient remains research.

• Korean Journal of Food Science and Technology
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• v.53 no.1
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• pp.34-39
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• 2021

This study investigated the anti-cancer effects of Salicornia herbacea L. fractions in human ovarian cancer cells (OVCAR-3). S. herbacea powder was extracted with 95% EtOH and sequentially fractionated with hexane, dichloromethane (DCM), ethyl acetate, butanol, and H2O. Further, the growth inhibitory effects of the six fractions were determined using the MTS assay. The DCM fraction dramatically decreased cell viability. Similarly, the cell cycle was arrested at the subG1 phase in DCM-treated cells. To confirm apoptosis, the cells were stained with annexin V/FITC-PI solution. Total, early, and late apoptotic cells were significantly increased in the DCM fraction. The mRNA expression of Bcl-2 was reduced, whereas the pro-apoptotic factors Bax and Bak were increased in DCM fraction-treated cells. These results indicated that the DCM fraction in S. herbacea exhibited strong apoptotic effects through the p53-dependent signaling pathway.

• Molecules and Cells
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• v.44 no.3
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• pp.146-159
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• 2021

DNA methylation, and consequent down-regulation, of tumour suppressor genes occurs in response to epigenetic stimuli during cancer development. Similarly, human oncoviruses, including human papillomavirus (HPV), up-regulate and augment DNA methyltransferase (DNMT) and histone deacetylase (HDAC) activities, thereby decreasing tumour suppressor genes (TSGs) expression. Ubiquitin-like containing PHD and RING finger domain 1 (UHRF1), an epigenetic regulator of DNA methylation, is overexpressed in HPV-induced cervical cancers. Here, we investigated the role of UHRF1 in cervical cancer by knocking down its expression in HeLa cells using lentiviral-encoded short hairpin (sh)RNA and performing cDNA microarrays. We detected significantly elevated expression of thioredoxin-interacting protein (TXNIP), a known TSG, in UHRF1-knockdown cells, and this gene is hypermethylated in cervical cancer tissue and cell lines, as indicated by whole-genome methylation analysis. Up-regulation of UHRF1 and decreased TXNIP were further detected in cervical cancer by western blot and immunohistochemistry and confirmed by Oncomine database analysis. Using chromatin immunoprecipitation, we identified the inverted CCAAT domain-containing UHRF1-binding site in the TXNIP promoter and demonstrated UHRF1 knockdown decreases UHRF1 promoter binding and enhances TXNIP expression through demethylation of this region. TXNIP promoter CpG methylation was further confirmed in cervical cancer tissue by pyrosequencing and methylation-specific polymerase chain reaction. Critically, down-regulation of UHRF1 by siRNA or UHRF1 antagonist (thymoquinone) induces cell cycle arrest and apoptosis, and ubiquitin-specific protease 7 (USP7), which stabilises and promotes UHRF1 function, is increased by HPV viral protein E6/E7 overexpression. These results indicate HPV might induce carcinogenesis through UHRF1-mediated TXNIP promoter methylation, thus suggesting a possible link between CpG methylation and cervical cancer.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.32 no.6
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• pp.373-383
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• 2020

In this study we established an operational storm-surge system for the northwestern pacific ocean, based on the NEMO (Nucleus for European Modeling of the Ocean). The system consists of the tide and the surge models. For more accurate storm surge prediction, it can be completed not only by applying more precise depth data, but also by optimal parameterization at the boundaries of the atmosphere and ocean. To this end, we conducted several sensitivity experiments related to the application of available bathymetry data, ocean bottom friction coefficient, and wind stress and air pressure on the ocean surface during August~September 2018 and the case of typhoon SOULIK. The results of comparison and verification are presented here, and they are compared with POM (Princeton Ocean Model) based Regional Tide Surge forecasting Model (RTSM). The results showed that the RTSM_NEMO model had a 29% and 20% decrease in Bias and RMSE respectively compared to the RTSM_POM model, and that the RTSM_NEMO model had a lower overall error than the RTSM_POM model for the case of typhoon SOULIK.

• KIPS Transactions on Software and Data Engineering
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• v.11 no.7
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• pp.291-298
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• 2022

In this paper, we present a method for dependency parsing with chunking in Korean. Dependency parsing is a task of determining a governor of every word in a sentence. In general, we used to determine the syntactic governor in Korean and should transform the syntactic structure into semantic structure for further processing like semantic analysis in natural language processing. There is a notorious problem to determine whether syntactic or semantic governor. For example, the syntactic governor of the word "먹고 (eat)" in the sentence "밥을 먹고 싶다 (would like to eat)" is "싶다 (would like to)", which is an auxiliary verb and therefore can not be a semantic governor. In order to mitigate this somewhat, we propose a Korean dependency parsing after chunking, which is a process of segmenting a sentence into constituents. A constituent is a word or a group of words that function as a single unit within a dependency structure and is called a chunk in this paper. Compared to traditional dependency parsing, there are some advantage of the proposed method: (1) The number of input units in parsing can be reduced and then the parsing speed could be faster. (2) The effectiveness of parsing can be improved by considering the relation between two head words in chunks. Through experiments for Sejong dependency corpus, we have shown that the USA and LAS of the proposed method are 86.48% and 84.56%, respectively and the number of input units is reduced by about 22%p.

• Korean Journal of Remote Sensing
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• v.38 no.6_2
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• pp.1709-1722
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• 2022

The rise in temperature induced by global warming caused in El Nino and La Nina, and abnormally changed the temperature of seawater. Rainfall concentrates in some locations due to abnormal variations in seawater temperature, causing frequent abnormal floods. It is important to rapidly detect flooded regions to recover and prevent human and property damage caused by floods. This is possible with synthetic aperture radar. This study aims to generate a model that directly derives flood-damaged areas by using modified U-NET and TerraSAR-X images based on Multi Kernel to reduce the effect of speckle noise through various characteristic map extraction and using two images before and after flooding as input data. To that purpose, two synthetic aperture radar (SAR) images were preprocessed to generate the model's input data, which was then applied to the modified U-NET structure to train the flood detection deep learning model. Through this method, the flood area could be detected at a high level with an average F1 score value of 0.966. This result is expected to contribute to the rapid recovery of flood-stricken areas and the derivation of flood-prevention measures.

• Journal of Appropriate Technology
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• v.6 no.2
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• pp.115-125
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• 2020

Housing issues such as mushrooming slums remain as chronic in most developing countries. Due to the state's restrained capacity, the housing-vulnerable's self-help approaches have been increasingly inevitable and vital for addressing the housing issues. However, there are still two challenges: securing good quality with economic efficiency, and climate change mitigation and adaptation. This study aims at doing an architectural experiment by developing and educating the production of eco-friendly interlocking stabilized soil bricks (ISSB) by employing vernacular materials and technologies for housing-vulnerable communities in Indonesia. In collaboration with a local architectural NGO, the study features a co-creation workshop in which 40 evicted households participate in the whole process. Soil analysis, mixed design, compression tests, and economic analysis are carried out. This paper illustrates that ISSB also has a high potential as an alternative to a burned brick or a cement block. The application of ISSB to self-help housing is expected to have socioeconomic and environmental effects, thereby facilitating the housing-vulnerable's self-help approaches and contributing to addressing the housing challenges in Indonesia.