• BMB Reports
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• v.42 no.4
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• pp.189-193
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• 2009

During development lymphoid tissue inducer (LTi) cells are the first hematopoietic cells to enter the secondary lymphoid anlagen and induce lymphoid tissue neogenesis. LTi cells induce lymphoid tissue neogensis by expressing a wide range of proteins that are associated with lymphoid organogenesis. Among these proteins, membrane-bound lymphotoxin (LT) $\alpha1\beta2$ has been identified as a critical component to this process. LT$\alpha1\beta2$ interacts with the LT$\beta$-receptor on stromal cells and this interaction induces up-regulation of adhesion molecules and production of chemokines that are necessary for the attraction, retention and organization of other cell types. Constitutive expression of LT$\alpha1\beta2$ in adult LTi cells can result in the formation of a lymphoid-like structure called tertiary lymphoid tissue. In this review, we summarize the function of fetal and adult LTi cells and their involvement in secondary and tertiary lymphoid tissue development in murine models.

• Journal of Advanced Marine Engineering and Technology
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• v.36 no.7
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• pp.919-926
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• 2012

In order to control a LTI(Linear Time Invariant) system subjected to system noise and measurement noise, first of all, it is necessary to estimate the state of system with reliability. Kalman filtering technique has been widely used to estimate the state of the stochastic LTI system with stationary noise characteristics because of its estimation ability versus algorithm simplicity. However, it often fails to estimate the state of the LTI system of which system parameter uncertainty exists partly and/or input uncertainty exists. In this paper, a new estimation technique based on Kalman filter is suggested for stochastic LTI system under parameter uncertainty and/or input uncertainty. A fuzzy estimation algorithm against uncertainties is introduced so as to compensate the state estimate filtered by Kalman filter. In order to verify the state estimation performance of the suggested technique, several simulations are accomplished.

• BMB Reports
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• v.41 no.6
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• pp.448-454
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• 2008

Two full-length cDNAs, PutPMP3-1 and PutPMP3-2, encoding PMP3 family proteins were isolated from Puccinellia tenuiflora, a monocotyledonous halophyte. Expression of both genes was induced by low temperature, salt stress, dehydration, ABA, and $NaHCO_3$. Transcripts of PutPMP3-2 were more strongly induced by these stresses relative to those of PutPMP3-1, particularly under low temperature and dehydration conditions. Expression of PutPMP3-1 and PutPMP3-2 in yeast mutants lacking the PMP3 gene can functionally complement the membrane hyper-polarization and salt sensitivity phenotypes resulting from PMP3 deletion. To compare the functions of PutPMP3-1 and PutPMP3-2, the orthologous genes in rice (OsLti6a and OsLti6b) were isolated. Both OsLti6a and OsLti6b could functionally complement the loss of PMP3 in yeast. PutPMP3-2 and OsLti6a were more effective in reversing membrane hyperpolarization than PutPMP3-1 and OsLti6b. However, the four yeast transformants each showed similar levels of salt tolerance. These results imply that these PMP3 family members don't function identically under different stress tolerance conditions.

• 제어로봇시스템학회:학술대회논문집
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• 1990.10b
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• pp.1139-1144
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• 1990

In this paper, we consider linear periodic discrete-time control systems under periodic compensation. Such a closed-loop system generally represents a periodic time-varying system. We examine the problem of finding a compensator such that the closed-loop system is realized as LTI model (if possible) with the closed-loop stability being satisfied. We present a necessary and sufficient condition for solving such problem and also give the characterization of realizable LTI models.

• IMMUNE NETWORK
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• v.10 no.4
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• pp.115-119
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• 2010

Lymphoid tissue inducer (LTi) cells have been characterized in mouse as a key cell when secondary lymphoid tissues are organized during development and memory T cells are formed after birth. In addition to their involvement in adaptive immune responses, recent studies show that they contribute to innate immune responses by producing large amount of interleukin (IL)-22 against microbial attack. Here, we compare IL-22-producing LTi and LTi-like cells in human and mouse and discuss their heterogeneity in different tissues.

• Proceedings of the KIEE Conference
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• 2004.11c
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• pp.265-267
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• 2004

A blind separation problem in a multiple-input-multiple-output (MIMO) linear time-invariant (LTI) system with finite-alphabet inputs is considered. A discrete-time matrix equation model is used to describe the input-output relation of the system in order to make full use of the advantages of modern digital signal processing techniques. At first, ambiguity problem is investigated. Then, based on the results of the investigation, a new identifiability condition is proposed for the case of an input-data set which is widely used in digital communication. A probability bound such that an arbitrary input matrix satisfies the identifiability condition is derived. Finally, Monte-Carlo simulation is performed to demonstrate the validity of our suggestions.

• Proceedings of the Korean Information Science Society Conference
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• 2011.06d
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• pp.28-31
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• 2011

최근 이러닝의 연구방향의 변화는 기존의 Courseware를 중심으로 한 LMS(Learning Management System)기반의 학습관리 위주의 기능에서 학습자의 학습행위를 보조하고 지원하기 위한 학습 환경의 제공으로 관심이 옮겨지고 있다. 기존 LMS에서는 여러 가지 문제점이 존재하고 있는데 학습자의 만족도를 높이기 위한 다양한 콘텐츠 수의 부족, 이종의 시스템간의 콘텐츠 재활용의 불가, 콘텐츠 단가의 하락으로 인한 고급의 콘텐츠 부재, 학습몰입도의 저하 등이 핵심이슈로 떠오르고 있다. 제안하는 시스템은 학습자들의 자기주도적인 학습을 가능하게 하는 다양한 학습도구를 제공하고 더불어 기반 플랫폼에 상관없이 이종의 시스템에서 모두 실행이 가능한 LTI 기반의 학습환경을 제공함으로써 학습자 스스로 학습계획과 교육 분야를 선택할 수 있어 스마트한 학습을 지원할 수 있다.

• Journal of Electrical Engineering and Technology
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• v.7 no.1
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• pp.124-131
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• 2012

This paper deals with robust stability of linear time-invariant (LTI) systems with unstructured uncertainties. A new relation between uncertainties and system poles perturbed by the uncertainties is derived from a graphical analysis. A stability criterion for LTI systems with uncertainties is proposed based on this result. The migration range of the poles in the proposed criterion is represented as the bound of uncertainties, the condition number of a system matrix, and the disc containing the poles of a given nominal system. Unlike the existing methods depending on the solutions of algebraic matrix equations, the proposed criterion provides a simpler way which does not involves algebraic matrix equations, and a more flexible root clustering approach by means of adjusting the center and the radius of the disc as well as the condition number.

• Proceedings of the KIEE Conference
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• 2004.05a
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• pp.10-12
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• 2004

Recently, Datta at al. [1] have developed a metDattad of obtaining the complete set of stabilizing PI, PID controllers for a given LTI system, in which tDattase are determined by solving a set of linear inequalities parameterized by the proportional(P) gain. In this paper, we provide a note about Dattaw Datta's idea can be extended to the problem of finding all stabilizing PD controllers and about an improved metDattad that allows us to calculate the admissible range of P gain more rigorously. An illustrative example is given.

• Computers and Concrete
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• v.7 no.6
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• pp.497-510
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• 2010

For better estimation of elastic property of concrete composites, the effect of Interfacial Transition Zone (ITZ) has been found to be significant. Numerical concrete composites models have been introduced using Finite Element Method (FEM), where ITZ is modeled as a thin shell surrounding aggregate. Therefore, difficulties arise from the mesh generation. In this study, a numerical concrete composites model in 3D based on FEM and random unit cell method is proposed to calculate elastic modulus of concrete composites with ITZ. The validity of the model has been verified by comparing the calculated elastic modulus with those obtained from other analytical and numerical models.