• Transactions of the Korean Society of Mechanical Engineers A
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• v.29 no.7 s.238
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• pp.955-963
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• 2005

This research investigates dynamic characteristics of a linear motion (LM) guide through a experimental result and theoretical analysis. The stiffness in the LM guide is determined by the preloading due to the minus clearance between the ball bearing and the contact surface and it can be derived by Hertzian contact theory and the nonlinear motion of equation. The vibration analysis is performed using Lagrange equations and its result agrees with the experiment result. Using the sensitivity analysis on design parameters such as the contact angles of ball bearings and the eccentricity of mass center, the variation of the natural frequencies can be predicted.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.05a
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• pp.463-464
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• 2010

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.11a
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• pp.527-528
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• 2010

• Transactions of the Korean Society of Automotive Engineers
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• v.18 no.6
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• pp.84-90
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• 2010

This paper presents the shape optimization process for the automotive wheel bearing seal lip using the finite element method and the response surface method. First, to predict performance of the bearing seal lip, we used the non-linear finite element analysis. And then, we compared the analysis results with the test results to verify the finite element model. The objective function in optimizing process was obtained from results of the mud slurry test, which is one of many tests for evaluating performance of wheel bearing. After the mud slurry test for the four models which have the similar cross-sectional shape, we measured the wear area of the seal lip and the moisture content in grease. The objective function has been chosen by comparing the results of mud slurry test and characteristics of seal lip, such as contact force, contact area, contact pressure, and interference. Finally, within limited design parameters, we suggested the optimized shape of seal lip, which is expected to improve the wear and the sealing effect of it.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.973-977
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• 2004

A pneumatic cylinder used to sliding seal which seal the element one to another in relative motion. It is difficult to accuracy control because of adhesion phenomenon. To confirm this phenomenon, it is carried to friction force test and analysis for bellows type rodless cylinder. In the rodless cylinder of this type, friction force test is very important. Through the theoretical analysis of shock absorber obtained the optimal design of bellows type rodless cylinder. As the result of the friction force test, LM Guide type is suitable for work under low friction force.

• Journal of the Korean Society for Precision Engineering
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• v.29 no.4
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• pp.409-416
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• 2012

Recently, surface modification technology is of importance to improve the wear resistance and the corrosive resistance for high accurate mechanical parts such as LM guide, Ball Screw and Roller Bearing etc., Those has generally featured on rolling contact mechanism to improve not only the wear and the friction, but also the accuracy and the corrosion performances. For surface modifications of high accurate mechanical parts, normally thermal spray, PVD, CVD and E.P. processes have been used with many materials such as DLC, raydent, W, Ni, Ti etc. Diamondlike carbon (DLC) films possess a combination of attractive properties and have been largely employed to modify the tribological behaviors such as friction, wear, corrosion, fretting fatigue, biocompatibility, etc. However, for rolling contact mechanism mechanical parts DLC films are needed to study for commercial benefit. Rolling contact mechanism has features on effects of cyclic motions and stresses, and also not simply sliding motions. The papers focused on the performance test of wear and corrosive resistance according to Me-DLC film thickness. And also, its thickness effect of wear analysis was carried out through the simulation of the maximum shear stress under the rolling contact surface. As the results, Me-DLC films have more potential to improve the wear resistance for high precision mechanical parts than raydent films.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.3351-3355
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• 2013

Photodynamic therapy (PDT) is a promising cancer treatment modality that uses dye-sensitized photooxidation of biologic matter in target tissue. This study explored effects of the photosensitizer BCPD-17 during PDT for osteosarcoma. LM-8 osteosarcoma cells were treated with BCPD-17 and cell viability after laser irradiation was assessed in vitro with the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assay. The effects of BCPD-17 during PDT recurrence were then examined on tumor-bearing mice in vivo. BCPD-17 had dosedependent cytotoxic effects on LM-8 osteosarcoma cells after laser irradiation which also had energy-dependent effects on the cells. The rate of local recurrence was reduced when marginal resection of mice tumors was followed by BCPD-17-mediated PDT. Our results indicated BCPD-17-mediated PDT in combination with marginal resection of tumors is a potentially new effective treatment for osteosarcoma.

• Journal of the Korean Society for Precision Engineering
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• v.29 no.10
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• pp.1070-1077
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• 2012

Virtual machine tools have been magnified recently as manufacturers could estimate performances of machine tools before design and manufacturing of them. However, it requires much time and efforts to make FEM models and predict precision of machine tools well because machine tools are composed of many joints such as bolt joints, LM joints, rotational bearing joints and mounts. Especially, we have studied computational modeling methods of bolt joints to predict precision of machine tools well in this paper. Stiffness and damping coefficients of bolt joints are investigated and generalized with respect to fasten forces through experiments and FEM analysis. Matrix 27 element of ANSYS is used and bolt joints are simplified as square areas with 8 nodes to apply stiffness and damping simultaneously. Additionally, coordinate transformation of matrix 27 for bolt joints is induced to apply to skewed bolt joints of machine tools and evaluate it using FEM analysis.

• Microbiology and Biotechnology Letters
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• v.28 no.2
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• pp.97-104
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• 2000

Screening of Biologically Active Essential Oils from Ligusticum tenuissimum. Kim, Min-Hae, Young-Gil Kim, Jin-Ha Lee, Keo-Pyo Hong, Jung-Ki Hong, Young-Joon Kong, and Hyeon-Yong Lee*. Division of Food and Biotechnology, Kangwon National University, Chunchon 200-701, Korea, 1 Regional Crop Development Station, Kangwon Agricultural Research & Extension Services, Chunchon 200-150, Korea-The biological activities of the crude essential oils from Ligusticum tenuissimum and the control(phthalic anhydride) were compared. About 60% of the growth of MCF7, A549, and Rep3B cells were inhibited by adding 1.0 mg/ml of the crude essential oils and below 40% was observed by the control. Cytotoxicity on human normal lung cell(IMR90) was scored as 34.4% for the crude oil and 26.4% for control, respectively. It was found that the crude essential oils were more effective than the control in anti mutagenecity tested by both Rec-assay and CRG V79 cells. The growth of human T-cell(Jurkat) was enhanced up to 1.21 times by adding the crude essential oil compared with the control. 50% of a-glucosidase activity was inhibited by both the crude essential oil and the control. ACE activities were inhibited 80.1 % and 65.3% by adding 1.0 mg/ml of the crude oil and the control, respectively. The higher enhancement of glutathione-S-transferase activity was observed in the crude oil than those in the control: 301 % v.s 234% at 1.0 mg/ml of the treatment. Thrombolytic activity was measured as 42.9% and 28.6% for the crude oil and the standard, respectively. The effect of the oil on the nerve cells PCI2, was observed as follows: the neurite of PCl2 cells was lengthened up to 255 /-lm longer than 205 /-lm of control. The number of neurite-bearing cells were about two times higher than control. The survival ratio of the crude essential oil was also increased up to 56.4% which was about two fold higher than in control.