• Title/Summary/Keyword: LIP Control

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Effects of TGF-$\beta$3 on Epithelial-mesenchymal transformation and Epidermal growth factor receptor expression in palatogenesis of chicken embryo (계태아 발생시 TGF-$\beta$3가 구개판 내측돌기상피의 상피간엽변환 및 상피성장인자수용체 발현에 미치는 영향)

  • Yang Byoung-Eun;Lee Jong-Ho
    • Korean Journal of Cleft Lip And Palate
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    • v.4 no.1
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    • pp.13-26
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    • 2001
  • Cleft lip and/or palate is the congenital orofacial malformation most commonly occurred in humans, The disease is multifactorial and is probably caused by genetic and/or environmental factors, So, there are many problems in research concerning etiology and in treatment of the disease, Even the most practiced and sophisticated methods of surgical repair are necessarily followed by scar contraction and fibrosis, which result in skeletal defects, dental abnormalities, cosmetic disfigurement, and speech impairment, As a result, Fetal surgery can be considered but practiced rarely when the deformity is not fatal to life, And treatment of cleft palate is performed in the form of medicine projection into uterus in animal experiments, Many studies show that growth factor and its receptor emerge from the developing palate; and the epidermal growth factor receptors have a important role in craniofacial development and in palatal fusion, The palatal morphogenesis of the avine is different from the mammal's; it takes the form of physiologic cleft palate, Recently, cleft palate fusion experiment was performed when the avine were in the period of palate formation through the exogenous TGF-β3 addition, and it showed that the exogenous TGF-β3 makes fusion of divided palate through certain process when cleft palate is occurred in palatal formation, In this study, I had the conformation of the fusion of cleft palate through the addition of TGF-β in case of chicken embryo, and observed the effect of TGF-β in EGF receptor distribution, And the following is the results of this study, 1. In case of the TGF-βl and β3 addition group, there was the decrease of EGFR(Epidermal Growth Factor Receptor) immunoreactivity in mesenchymal cells beneath the medial edge epithelium and also in epithelial mesenchymal interface which is between medial edge epithelium and nasal septum in 72 hours, 2, The immunoreactivity of the control group resembles that of normal chicken embryo palate in development, 3. In the view through fluorescence confocal microscopy, there was confluence in TGF-β3 addition group, This shows that the confluence induced by exogenous TGF-β3 is related to EGFR expression in palate of chicken embryo, which is a physiologic cleft palate model.

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Maxillary Distraction Osteogenesis Using $TS-MD^{(R)}$ (Trans-sinusoidal Maxillary distractor) on Cleft Patients (Trans-sinusoidal maxillary distractor($TS-MD^{(R)}$)를 이용한 구순구개열 환자에서의 상악골 골신장술)

  • Paeng, Jun-Young;Lee, Il-Gu;Myoung, Hoon;Hwang, Soon-Jung;Seo, Byoung-Moo;Choe, Jin-Yeong;Lee, Jong-Ho;Choung, Pill-Hoon;Kim, Myung-Jin
    • Korean Journal of Cleft Lip And Palate
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    • v.8 no.2
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    • pp.71-79
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    • 2005
  • Purpose: Maxillary hypoplasia is a common developmental problem of cleft lip and palate. Fair results with distraction osteogenesis have been reported especially when these patients need a large amount of maxillary advancement, instead of orthognathic surgery. The purpose of this study is to evaluate the clinical results with a relatively new distractor, $TS-MD^{(R)}$ (Trans-sinusoidal maxillary distractor, KLS Martin, Tuttlingen, Germany) which was used for the advancement of the maxilla in the cleft patients. Patients and Method: Distraction osteogenesis using $TS-MD^{(R)}$ was performed for four CLP patients (three males and one female) who had maxillary hypoplasia. All patients were over 16 years old. As three patients showed mandibular prognathism as well, bilateral sagittal split ramus osteotomy for mandibular setback was performed at the same time. After consolidation periods of 4 to 12 weeks, the distraction devices were removed and miniplates were placed for simultaneous internal fixation. Results: Three patients showed a large amount of incisal overbite but one patient did not have sufficient maxillary advancement. Le Fort I osteotomy, maxillary advancement and internal fixation should have been performed for the patient when removing the distraction devices. Different from the $clinician{\box}s$ expectation, the amount of maxillary advancement using $TS-MD^{(R)}$ was not sufficient, although the device has rigid mechanical property. Rotation of maxilla during distraction forward and downward was also observed. Conclusion: Even though the maxillary advancement with $TS-MD^{(R)}$ device could be achieved, the clinical control of some characteristics related with the device was necessary. More clinical studies on $TS-MD^{(R)}$ should be performed.

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Distribution of maternal risk factors for orofacial cleft in infants in Indonesia: a multicenter prospective study

  • Andi Tajrin;M. Ruslin;Muh. Irfan Rasul;Nurwahida;Hadira;Husni Mubarak;Katharina Oginawati;Nurul Fahimah;Ikeu Tanziha;Annisa Dwi Damayanti;Utriweni Mukhaiyar;Asri Arumsari;Ida Ayu Astuti;Farah Asnely Putri;Shinta Silvia
    • Archives of Craniofacial Surgery
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    • v.25 no.1
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    • pp.11-16
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    • 2024
  • Background: The pathogenesis of orofacial cleft (OFC) is multifactorial, involving both genetic and non-genetic factors, the latter of which play a key role in the development of these anomalies. This paper addresses the incidence of OFC in Indonesia, with a focus on identifying and examining the distribution of contributory factors, including parental medical history, pregnancy history, and environmental influences. Methods: The study was conducted through the collection of primary data. An interdisciplinary research team from Indonesia administered a standardized questionnaire to parents who had children with OFC and who had provided informed consent. The case group comprised 133 children born with cleft lip and/or palate, and the control was 133 noncleft children born full-term. The risk factors associated with OFC anomalies were analyzed using the chi-square test and logistic regression. All statistical analyses were performed using SPSS version 25. A p-value of 0.05 or less was considered to indicate statistical significance. Results: The study comprised 138 children, of whom 82 were boys (59.4%) and 56 were girls (40.6%). Among them, 45 patients (32.6%) presented with both cleft lip and cleft palate, 25 individuals (18.1%) had a cleft palate only, and 28 patients (20.3%) had a cleft lip only. OFC was found to be significantly associated with a maternal family history of congenital birth defects (p<0.05), complications during the first trimester (p<0.05), consumption of local fish (p<0.05), caffeine intake (p<0.05), prolonged medication use (p<0.05), immunization history (p<0.05), passive smoking (p<0.05), and X-ray exposure during pregnancy (p<0.05). Conclusion: The findings indicate close relationships between the incidence of OFC and maternal medical history, prenatal factors, and environmental influences.

Current Control Circuit for Drive of Single Phase Permanent Magnet Motor Using H-Bridge (단상 영구자석 모타 구동을 위한 H-Bridge 의 전류제어회로)

  • Woo, Kyung-Il;Kwon, Byung-Il;Kim, Ki-Bong
    • Proceedings of the KIEE Conference
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    • 2002.07b
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    • pp.939-942
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    • 2002
  • 본문의 내용은 영구자석을 사용한 단상 브러시리스 모타의 구동을 위한 H-Brdige 구동회로에 적용된 전류제어 회로에 관한 실험결과이다. 부하전류가 목표치 이상인 경우 enable 를 차단하면 순간적으로 센서저항의 전위가 0 으로 되고 이로인해 다시 순간적으로 스위칭이 이루어 지므로 매우 빠른 주기로 스위칭을 반복한다. 이 문제점을 해결하기 위하여 래칭회로를 필요로 하는데, 본 제안에서는 두 개의 NAND GATE 와 하나의 NOT GATE, 그리고 RC network 를 조합하여 LIP-FLOP 과 시지연을 이루는 방법을 실현하였다. 이와 같은 전류제어회로는 constant off time 의 특성을 가지는데, 일반적으로 사용되는 PWM 제어회로에 비하여 매우 단순하면서도, 저항부하 및 모타부하에 대해 공히 능동적으로 작동함을 입증하고 있다. 본문에서는 제안된 전류제한회로의 구조와 H-bridge 구동모드, 그리고 전기적 특성에 대한 연구결과를 설명한다.

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A review on numerical models and controllers for biped locomotion over leveled and uneven terrains

  • Varma, Navaneeth;Jolly, K.G.;Suresh, K.S.
    • Advances in robotics research
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    • v.2 no.2
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    • pp.151-159
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    • 2018
  • The evolution of bipedal robots was the foundation stone for development of Humanoid robots. The highly complex and non-linear dynamic of human walking made it very difficult for researchers to simulate the gait patterns under different conditions. Simple controllers were developed initially using basic mechanics like Linear Inverted Pendulum (LIP) model and later on advanced into complex control systems with dynamic stability with the help of high accuracy feedback systems and efficient real-time optimization algorithms. This paper illustrates a number of significant mathematical models and controllers developed so far in the field of bipeds and humanoids. The key facts and ideas are extracted and categorized in order to describe it in a comprehensible structure.

Smooth and uniform coated films on flexible substrates by optimization of slot-die process parameters

  • Jeong, Guk-Chae;Jeong, Tae-Jeong;Kim, Yeong-Guk;Choe, Cheol-Jin
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.11a
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    • pp.179-179
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    • 2009
  • For the deposition of the semiconductor nanocrystals or quantum dots, it is required to have the substrates with smooth surface roughness. Slot-die coating method wad adopted and optimized varying the processing parameters like coating speed, gap distance, solution concentration, etc to get the smooth coated films on flexible substrates. The coating speed in slot-die method was varied from 1 m/min to 2.5 m/min focusing especially on its industrial usage. The gap distance between the substrate surface and slot-die lip was changed also to control mainly the thickness of coated films.

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Experimental Study for the Prevention of Cavitation Damage in the Diesel Fuel Injection Pumps (디젤엔진 연료분사펌프 캐비테이션 손상 방지를 위한 실험적 연구)

  • Kim, Dong-Hun;Park, Tae-Hyung;Heo, Jeong-Yun;Ryu, Seung-Hyup;Kang, Sang-Lip
    • Proceedings of the Korean Society of Marine Engineers Conference
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    • 2011.10a
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    • pp.61-61
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    • 2011
  • Cavitation phenomena during the injection process of the conventional fuel injection pump for a medium-speed diesel engine can cause surface damage with material removal or round-off on the plunger and barrel port and may shorten their expected life time. An experiment of flow visualization was carried out to investigate the main cause of these cavitation damages and find the prevention method. Experimental results of flow visualization show that these damages are mainly affected by fountain-like cavitation and jet-type cavitation generated before and after the end of fuel delivery process and therefore the prevention method was designed to control these cavitation flows. From the visualization and endurance test, it was proved that this method can effectively prevent cavitation damages by controlling cavitation flows.

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Supersonic Intake Design & Flow Control Analysis using Bleeding Condition (초음속 흡입구 형상 설계 및 Bleeding을 활용한 유동제어 연구)

  • Choe, Jae-Hwan;Cheon, So-Min;Kim, Jong-Am
    • Proceeding of EDISON Challenge
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    • 2012.04a
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    • pp.77-80
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    • 2012
  • 초음속 흡입구는 설계점에서 안정적으로 작동하지만 설계점 밖에서는 엔진성능이 급격히 감소하거나 층 격파 불안정 문제가 발생할 수 있다. 초음속 흡입구의 일반적인 특성을 파악하기 위해 2단 꺾임각을 갖는 외부 압축식 2차원 흡입구를 설계하고 EDISON_열유체 시스템을 이용하여 최종적으로 설계 마하수 2.5에서 작동하는 형상을 얻었다. 그러나 설계 마하수 이하의 영역에서는 충격파-경계층, 충격파간 상호작용으로 인해 유동에서 박리가 발생하고 최종적으로 흡입구 목을 질식시켜 아임계 상태로 천이된다. 이를 해결하기 위해 유동 제어 방법 중 하나인 bleeding을 이용하여 경계층을 제거하거나 유동의 박리를 방지하여 충격파를 cowl lip 전방에 안정하게 고정시킬 수 있었으며, 결과적으로 목적하였던 마하수 2.0에서 2.5에 이르는 작동 영역에서 강건하게 운용될 수 있는 초음속 흡입구를 설계하였다.

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Lipreading과 음성인식에 의한 향상된 화자 인증 시스템

  • 지승남;이종수
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.274-274
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    • 2000
  • In the future, the convenient speech command system will become an widely-using interface in automation systems. But the previous research in speech recognition didn't give satisfactory recognition results for the practical realization in the noise environment. The purpose of this research is the development of a practical system, which reliably recognizes the speech command of the registered users, by complementing an existing research which used the image information with the speech signal. For the lip-reading feature extraction from a image, we used the DWT(Discrete Wavelet Transform), which reduces the size and gives useful characteristics of the original image. And to enhance the robustness to the environmental changes of speakers, we acquired the speech signal by stereo method. We designed an economic stand-alone system, which adopted a Bt829 and an AD1819B with a TMS320C31 DSP based add-on board.

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Media-Synchronization Control Algorithm for Multimedia Data Streaming (멀티미디어 데이터 스트리밍을 위한 미디어 동기방식 제어 알고리즘)

  • Shin, Dong-Jin;Kim, Su-Chang;Lee, Seung-Min;Song, Byung-Kwon;Jeong, Tae-Eui
    • Proceedings of the Korea Information Processing Society Conference
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    • 2002.04b
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    • pp.1329-1332
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    • 2002
  • 최근 고속 통신망과 멀티미디어 기술의 급속한 발전으로 다양한 멀티미디어 서비스에 대한 연구와 그에 대한 응용 개발이 활발하게 이루어지고 있다. 그러나, 멀티미디어 응용 서비스는 기존의 단일미디어 서비스와는 달리 다양한 미디어의 통합된 전송을 필요로 하며, 개별 미디어의 정확한 연속성 및 관련된 미디어들 간의 적절한 시간적 동기화가 확보된 실시간 재생이 요구되는 고도화된 처리 기술을 필요로 하기 때문에 멀티미디어 동기화 알고리즘에 대한 연구는 필수적이고 매우 중요하다고 볼 수 있다. 본 논문은 Multimedia Data Streaming 을 위한 미디어 동기 방식 제어 알고리즘 고안 및 Lip Sync 방식 설계에 그 연구 목적이 있다.

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