Jae In, Jung;Hyun Sook, Lee;So Mi, Kim;Soyeon, Kim;Jihoon, Lim;Moonjea, Woo;Eun Ji, Kim
Nutrition Research and Practice
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v.16
no.6
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pp.685-699
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2022
BACKGROUND/OBJECTIVES: Platycodon grandiflorum (PG) has long been known as a medicinal herb effective in various diseases, including bronchitis and asthma, but is still more widely used for food. Fermentation methods are being applied to increase the pharmacological composition of PG extracts and commercialize them with high added value. This study examines the hydrolyzed and fermented PG extract (HFPGE) fermented with Lactobacillus casei in RAW 264.7 cells, and investigates the effect of amplifying the immune and the probable molecular mechanism. MATERIALS/METHODS: HFPGE's total phenolic, flavonoid, saponin, and platycodin D contents were analyzed by colorimetric analysis or high-performance liquid chromatography. Cell viability was measured by the MTT assay. Phagocytic activity was analyzed by a phagocytosis assay kit, nitric oxide (NO) production by a Griess reagent system, and cytokines by enzyme-linked immunosorbent assay kits. The mRNA expressions of inducible nitric oxide synthase (iNOS) and cytokines were analyzed by reverse transcription-polymerase chain reaction, whereas MAPK and nuclear factor (NF)-κB activation were analyzed by Western blots. RESULTS: Compared to PGE, HFPGE was determined to contain 13.76 times and 6.69 times higher contents of crude saponin and platycodin D, respectively. HFPGE promoted cell proliferation and phagocytosis in RAW 264.7 cells and regulated the NO production and iNOS expression. Treatment with HFPGE also resulted in increased production of interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, C-X-C motif chemokine ligand10, granulocyte-colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and monocyte chemoattractant protein-1, and the mRNA expressions of these cytokines. HFPGE also resulted in significantly increasing the phosphorylation of NF-κB p65, extracellular signal-regulated kinase, and c-Jun N-terminal kinase. CONCLUSIONS: Taken together, our results imply that fermentation and hydrolysis result in the extraction of more active ingredients of PG. Furthermore, we determined that HFPGE exerts immunostimulatory activity via the MAPK and NF-κB signaling pathways.
KIPS Transactions on Computer and Communication Systems
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v.11
no.11
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pp.381-394
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2022
Recently, due to the personalization and customization of data, Internet-based services have increased requirements for real-time processing, such as real-time AI inference and data analysis, which must be handled immediately according to the user's situation or requirement. Real-time tasks have a set deadline from the start of each task to the return of the results, and the guarantee of the deadline is directly linked to the quality of the services. However, traditional container systems are limited in operating real-time tasks because they do not provide the ability to allocate and manage deadlines for tasks executed in containers. In addition, tasks such as AI inference and data analysis basically utilize graphical processing units (GPU), which typically have performance impacts on each other because performance isolation is not provided between containers. And the resource usage of the node alone cannot determine the deadline guarantee rate of each container or whether to deploy a new real-time container. In this paper, we propose a monitoring technique for tracking and managing the execution status of deadlines and real-time GPU tasks in containers to support real-time processing of GPU tasks running on containers, and a node list management technique for container placement on appropriate nodes to ensure deadlines. Furthermore, we demonstrate from experiments that the proposed technique has a very small impact on the system.
Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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v.40
no.4
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pp.343-350
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2022
The computerization project for underground facilities in Korea began in earnest after the city gas explosion in Seoul in 1994, and the Daegu subway explosion in 1995. As such a large-scale gas explosion accident caused enormous economic loss including human casualties and potential benefits, the need for computerized for efficient management of underground facilities was greatly emphasized in society. Meantime, computerization of underground facilities has been carried out according to the basic plan for building national geographic information system. In this study, problems were identified based on the current status of construction and management of underground facility information, as well as laws and regulations, and directions for establishing quality standards were presented. In addition, construction work standards such as 「Public Survey Work Regulations」, design standards, standard specifications, and technical specifications, gas technology standards, design standards, and communication works so that underground facility information can be linked and utilized in construction work by examining the linkage of the underground facilities, the targets that can be used for quality level information on underground facilities were derived, and a proposal to revise the construction standards was presented. In the future, if the quality standards are established, it is expected that the accuracy and utilization in the construction field will be increased.
Lee, Soo Young;Kang, Dong Huy;Lee, Doyun;Kim, Heechul
Journal of the Korean Academy of Esthetic Dentistry
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v.30
no.2
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pp.71-90
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2021
The virtual patient dataset is a collection of diagnostic data from various sources acquired from a single patient into a coordinate system of three-dimensional visualization. Virtual patient dataset makes it possible to establish a treatment plan, simulate various treatment procedures, and create a treatment planning delivery device. Clinicians can design and simulate a patient's smile on the virtual patient dataset and select the optimal result from the diagnostic process. The selected treatment plan can be delivered identically to the patient using manufacturing techniques such as 3D printing, milling, and injection molding. The delivery of this treatment plan can be linked to the final prosthesis through mockup confirmation through provisional restoration fabrication and delivery in the patient's mouth. In this way, if the diagnostic data superimposition and processing accuracy during the manufacturing process are guaranteed, 3D digital smile design simulated in 3D visualization can be accurately delivered to the real patient. As a clinical application method of the virtual patient dataset, we suggest a decision-making method that can exclude occlusal adjustment treatment from the treatment plan through the digital occlusal pressure analysis. A comparative analysis of whole-body scans before and after temporomandibular joint treatment was suggested for adolescent idiopathic scoliosis patients with temporomandibular joint disease. Occlusal plane and smile aesthetic analysis based on the virtual patient dataset was presented when treating patients with complete dentures.
Based on the service scenario proposed by the existing Kim Tae-wan (2018) who can safely evacuate inmates with the help of a mobile application linked to a fire detection system in the event of a fire, the final purpose of this study is to develop the scenario by incorporating more realistic scenarios with mobile stimuli that can help them escape or act through the Delph In addition, to make the scenarios produced more realistic considering the structure and copper lines of a typical building, expert scenario verification and Delphi technique were applied to exclude unnecessary or impractical aspects of the existing scenarios. The results of the second Delphi survey showed that the primary psychology that could be seen at the time of the fire alarm were doubts, safety concerns and alarm, and the results of the second Delphi survey were analyzed, and the satisfaction of the content adequacy (CVR), convergence, and consensus was derived. Finally, this was applied to create a scenario in which a mobile application was assisted to evacuate the fire response phase. This study will allow the use of methods to increase the evacuation rate of those who are in the event of a fire.
Journal of Korean Home Economics Education Association
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v.34
no.4
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pp.113-129
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2022
The purpose of this study is to propose implications by analyzing the textiles and clothing curriculum of vocational high schools. Literature and data were analyzed, surveys and FGI were conducted, and the following research results were derived. First, many schools chose 'Basic dress design' or 'Basic dress composition' as basic subjects. Through this, it was confirmed that technical training for practice is a priority for vocational schools, and that more discussion is needed regarding the lack of theoretical subjects. Second, similarly to the basic subjects, practical subjects offered are concentrated on 2 to 3 subjects. The teachers asserted that some subjects such as 'Knit apparel production' and the 'Leather and fur design production', which require a lot of equipment and advanced technology, cannot be offered without support from the government. Third, the NCS competency unit of the practical subjects is easy to proceed with the class or is closely concentrated on the type of manpower training presented by each department. Fourth, this study proposes that for technical education to expand students' choice, it is necessary to cultivate teachers competencies linked to the industry. The results of this study are expected to provide basic data on the organization of the next textiles and clothing professional curriculum and help understand vocational education at vocational high schools. In addition, it is believed that this study will contribute to developing and settling various subjects when the high school credit system is implemented by expanding students' choice of major-related subjects.
As real estate values rise, interest in cadastral resurvey is increasing. Accordingly, a cadastral resurvey project is actively underway for drone operation through securing work efficiency and improving accuracy. The need for utilization and management of cadastral resurvey results (drone images) is being raised, and through this study, a 3D spatial information platform was developed to solve the existing drone image management and utilization limitations and to provide drone image-based 3D cadastral information. It is proposed to build and use. The study area was selected as a district that completed the latest cadastral resurvey project in which the study was organized in February 2023. Afterwards, a web-based 3D platform was applied to the study to solve the user's spatial limitations, and the platform was designed and implemented based on drone images, spatial information, and attribute information. Major functions such as visualization of cadastral resurvey results based on 3D information and comparison of performance between previous cadastral maps and final cadastral maps were implemented. Through the open platform established in this study, anyone can easily utilize the cadastral resurvey results, and it is expected to utilize and share systematic cadastral resurvey results based on 3-dimensional information that reflects the actual business district. In addition, a continuous management plan was proposed by integrating the distributed results into one platform. It is expected that the usability of the 3D platform will be further improved if a platform is established for the whole country in the future and a service linked to the cadastral resurvey administrative system is established.
KSCE Journal of Civil and Environmental Engineering Research
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v.29
no.1D
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pp.17-23
/
2009
Due to the rapid increase of vehicles on the street, Korean society is facing worsening traffic congestions and air pollutions. Also, the oil price pickup has led to increasing need for the use of public transportation. In particular, transfering among public transportation may be a main factor for riders who are commuting for a long distance journey. In order to ensure such connectivity, transfer stations have been actively built in Korea. However, it would be necessary to shift those vehicles, from cars to public transportations by enhancing the users' satisfaction with public transportation through strategies for minimizing the users' waiting cost by building an efficient connective system between transportation modes as well as the preparation of aforementioned transfer stations. Therefore, this study aimed to develop an algorithm for minimizing transferring passengers' waiting costs based on service intervals of linked buses within the transfer facilities. In order to adjust the service interval, we calculated the total costs, involving the wait cost of transfer passengers and bus operation costs, and produced an allocation interval, that would minimize the costs. We selected a KTX departing from Seoul station, and a No. 6014 bus route in Gwangmyeong city where it starts from the Gwangmyeong station in order to for verifying the model. Then, the transfer passengers' total waitting cost was reduced equivalent to the maximum of 212 minutes, and it revealed that the model performed very effectively.
Journal of the Korean Society for information Management
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v.39
no.4
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pp.99-125
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2022
In order to understand a record, not only the contents of the record but also the production background and work context of the record must be grasped. It also requires a function that makes it easy to find related records scattered across various departments and agencies. Accordingly, the 'linkage' of information in archival information services is becoming more important. NAK also emphasizes 'linkage' as a search service function of the archives management system, but some problems were identified at the National Archives Portal Service (NAPS) such as a lack of linkage with authority data, disruption of internal service, and absence of linkage with other related organizations. To solve the limitations of the NAPS, we selected and analyzed advanced record management institutions that have built an ideal linkage service; checked the overall linkage structure of these institutions; and identified characteristics that could not be seen by other institutions. Also, elements that can be adopted from the NAPS were derived. Next, the current status of the NAPS linkage structure was analyzed to identify the parts that were not linked and the items that need to be improved in the linkage method, and specific advancement plans were suggested to solve these problems. The purpose of this study is to increase users' satisfaction with search and to advance the accessibility and utilization of records and internal services through improved linkage services of NAPS.
This study investigated the means-end chain theory more concretely through the APT hard laddering technique. This is carrying out a questionnaire survey targeting users by hair salon type, and the items drawn from the qualitative laddering technique are applied. The technique is a comparative analysis of each attribute, consequences, and value item by analyzing each step's questions. The results are as follows. First, hairdresser's ability, acceptance of individual-customized opinions, and cheap price were the most mentioned items in the selection attributes. As for the consequences items, image transformation, neatness, novelty, and psychological stability were drawn in order. The items indicated as important among the value items were satisfaction, followed by happiness, confidence, beauty, and bond. Second, the remarkable selection attributes, irrelevant of hair salon type, was revealed as hairdresser's ability and the key values pursued when using a hair salon were drawn as satisfaction, confidence, and beauty. From this result, it was found that meeting the desire of consumers using hair salons can be linked with ultimately pursued values. It was also verified that partial differences were shown by hair salon type and this meant that consumers' desire and expected benefits were different by hair salon type. Although this study drew value perception through comparison with hair salon types based on the means-end chain theory, it was confirmed that the most important selection attribute was hairdresser's ability and they select and use hair salons to gain satisfaction and confidence.
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