• Journal of Advanced Navigation Technology
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• v.13 no.5
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• pp.720-725
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• 2009

This paper proposes a modified Wilkinson power divider using a zero-degree composit right/left-handed(CRLH) transmission line to obtain a isolation between ports. A zero-degree CRLH transmission line, which has a total electrical length of zero, consists of a RH(Right-Handed) transmission line of a negative phase characteristic and a LH (Left-Handed) transmission line of a positive phase characteristic. To validate a value of zero-degree CRLH transmission line, the electrical lengths of RH and LH transmission line select $-30^{\circ}$ and $+30^{\circ}$ and a 2-way Wilkinson divider designed, we are measured S21 of -3.3dB, S11 of -27.5dB and S23 of -25dB at 1GHz center frequency. These characteristics are same the conventional divider using RH transmission line.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5177-5182
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• 2012

Purpose: To compare the efficacy and safety of epidermal growth factor receptor tyrosine kinase inhibitormonotherapy (EFGR-TKIs: gefitinib or erlotinib) with standard second-line chemotherapy (single agent docetaxel or pemetrexed) in previously treated advanced non-small-cell lung cancer (NSCLC). Methods: We systematically searched for randomized clinical trials that compared EGFR-TKI monotherapy with standard second-line chemotherapy in previously treated advanced NSCLC. The end points were overall survival (OS), progression-free survival (PFS), overall response rate (ORR), 1-year survival rate (1-year SR) and grade 3 or 4 toxicities. The pooled hazard ratio (HR) or risk ratio (RR), with their corresponding 95% confidence intervals (CI) were calculated employing fixed- or random-effects models depending on the heterogeneity of the included trials. Results: Eight randomized controlled trials (totally 3218 patients) were eligible. Our meta-analysis results showed that EGFR-TKIs were comparable to standard second-line chemotherapy for advanced NSCLC in terms of overall survival (HR 1.00, 95%CI 0.92-1.10; p=0.943), progression-free survival (HR 0.90, 95%CI 0.75-1.08, P=0.258) and 1-year-survival rate (RR 0.97, 95%CI 0.87-1.08, P=0.619), and the overall response rate was higher in patients who receiving EGFR-TKIs(RR 1.50, 95%CI 1.22-1.83, P=0.000). Sub-group analysis demonstrated that EGFR-TKI monotherapy significantly improved PFS (HR 0.73, 95%CI: 0.55-0.97, p=0.03) and ORR (RR 1.96, 95%CI: 1.46-2.63, p=0.000) in East Asian patients, but it did not translate into increase in OS and 1-year SR. Furthermore, there were fewer incidences of grade 3 or 4 neutropenia, febrile neutropenia and neutrotoxicity in EGFR-TKI monotherapy group, excluding grade 3 or 4 rash. Conclusion: Both interventions had comparable efficacy as second-line treatments for patients with advanced NSCLC, and EGFR-TKI monotherapy was associated with less toxicity and better tolerability. Moreover, our data also demonstrated that EGFR-TKImonotherapy tended to be more effective in East Asian patients in terms of PFS and ORR compared with standard second-line chemotherapy. These results should help inform decisions about patient management and design of future trials.

• Journal of applied mathematics & informatics
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• v.42 no.1
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• pp.159-167
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• 2024

The Topological indices are known as Mathematical characterization of molecules. In this paper, we have studied line graph of subdivision and semi-total point graph of triangular benzenoid, polynomino chains of 8-cycles and graphene sheet through forgotten and first Zagreb indices.

• Journal of Fashion Business
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• v.1 no.3
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• pp.95-102
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• 1997

This study is aimed for men's jacket draft not only to other style but also helping for men's jacket fits for trend by presenting the course to get a style we want by adding to the partial drafty changes in existing pattern of men's formal jacket selected two kinds of men's jacket style fit for 1997 S/S trend. In this 1997 S/S trend, the trend I of the characteristic formal jacket is a style slim expressed over the basic formal wear, and trend II of the characteristic casual jacket appears to women's wear that roundly expressed by collar line of V-zone returened back by the shoulder line of jacket made of a big diagonal wrinkled line of X-style in front centered around a button of center front line. In this study, it called that the existing traditional formal jacket of men is a A style of jacket and jacket style I, II is a jacket B, C style. Jacket A, B, C style, a distingtion in draft that added to make form an oblique wrinkled line of the X-shaped-making artificially to the front button line sharply distinguished by eyes will be come out by control of front neck width over the back neck width. According to this, we shall be found that place of front neck point is a cardinal point in draft that will be added any changes in a style of jacket.

• Transactions of The Korea Fluid Power Systems Society
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• v.1 no.2
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• pp.20-25
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• 2004

In this study, a position control characteristics of pneumatic cylinder with transmission line is analyzed. Dynamic characteristics of transmission line using compressible fluid is changed by the flowing stiles of the fluid the diameter and the length of the line. But, the effect of the change of dynamic characteristics of transmission line by the flowing states on the position control characteristics can be neglected because of the friction force of the pneumatic cylinder. So, We assume that the position control characteristics is affected by the diameter and length of the transmission line. The experimental results according to the change of parameter of the transmission line show that the relation between the parameter of the transmission line and the position control characteristics of pneumatic cylinder driving system with the transmission line.

• Communications of the Korean Mathematical Society
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• v.34 no.1
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• pp.333-349
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• 2019

The paper study the curvature theory of a line-trajectory of constant Disteli-axis, according to the invariants of the axodes of moving body in spatial motion. A necessary and sufficient condition for a line-trajectory to be a constant Disteli-axis is derived. From which new proofs of the Disteli's formulae and concise explicit expressions of the inflection line congruence are directly obtained. The obtained explicit equations degenerate into a quadratic form, which can easily give a clear insight into the geometric properties of a line-trajectory of constant Disteli-axis with the theory of line congruence. The degenerated cases of the Burmester lines are discussed according to dual points having specific trajectories.

• Journal of Microbiology
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• v.37 no.2
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• pp.86-89
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• 1999

An OTHBVS cell line from HepG2 was established. This cell line stably expresses the human hepatitis B virus (HBV) middle S protein that includes the preS2 region which is important for HBV particle entry into the hepatocyte. To establish this cell line, the middle S open reading frame (ORF), with a promoter located in the 5' region and enhancer located in the 3' region, was cloned downstream from the metallothionine (MT) promoter of the OT1529 vector. In this vector, expression of the middle S protein was constructed to be regulated by its own promoter and enhancer. Expression of the large S protein which contains the preS1 region in addition to the middle S protein was designed to be regulated by the MT promoter. When extracts of OTHBVS cells were examined with an S protein detection kit (RPHA, Korea Green Cross Co.), an S protein was detected. Total mRNA of OTHBVS cell examined by northern blot analysis with an S ORF probe revealed small/middle S transcripts (2.1 kb). When the MT promoter was induced by Zn, large S transcripts (2.4 kb) were detected. The GP36 and GP33 middle S proteins were presumably detected, but large S proteins were not detected by immunostain analysis using anti-preS2 antibody.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.11
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• pp.1484-1491
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• 2020

Since the slot line transmits electric and magnetic signals through the slot, the size of the slot greatly affects the signal power loss. In order to have low loss, the slot line is mainly used at a high frequency of above 3GHz on a substrate having a high dielectric constant(er). This paper proposes the 4:1 impedance transformer using a slot line on TLC-30 laminate (h=20mil, er=3.0; Taconic) being a relatively low dielectric constant at a frequency of 1.85GHz. In the proposed impedance transformer, the dielectric resonator is arranged on the slot line to reduce signal loss occurring at the slot line. The proposed 4:1 microstrip-slot line impedance transformer fabricated using a (Zr,Sn)TiO4 dielectric resonator(er=38) has the transmission loss(S21) of -0.375dB and the reflection value(S11) of -27.6dB at 1.855GHz. This confirms that the slot line can be stably used even in a low dielectric constant substrate and a low frequency region by using a dielectric resonator.

• Proceedings of the KSAR Conference
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• 2003.06a
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• pp.73-73
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• 2003

본 연구는 돼지 체세포의 clonal cell lines을 효율적으로 확립할 수 있는 배양방법을 제시하기 위하여 실시하였다. 50일령의 돼지태아로부터 섬유아세포를 회수하여 2회 계대배양 후 단일 세포를 96-well plate와 4-well dish에서 배양하여 배양액내의 FBS농도(10, 30, 50%), 첨가제(catalase, $\beta$-mercaptoethanol; BME), 세포의 크기(<16, 16~20, 20<) 및 형태(smooth, rough)에 따른 cell line 확립 효율을 검토하였다. FBS 농도에 따른 clonal line 확립 효율과 PD를 검토한 결과, 효율에 있어서 30% FBS 처리구(5.1%)가 10%(0.3%) 및 50%처리구(2.1%)보다 비교적 높게 나타났으나 유의적 차이는 없었으며, PD의 경우는 10, 30, 50%처리구에서 각각 36.7, 29.4, 26.3 시간으로 FBS 농도가 증가할수록 PD 시간이 유의적으로 짧아졌다(p<0.05). 배양액 첨가제에 있어서 BME 가시 무처리구나 catalase 첨가시보다 유의적으로 높은 효율을 보였으며(11.4%, 3.2%, 3.2%; p<0.05), PD 시간은 짧게 나타났다(23.6, 25.5, 28.1; p<0.05). 그러나 catalase는 cell line 확립 효율에 영향을 미치지 않는 것으로 나타났다. 세포의 크기에 따른 cell line 확립효율은 5.2~8.2%로 크기에 따른 차이는 보이지 않았으며, PD 또한 23.7~27.9 시간으로 세포 크기에 따른 차이는 없었다. 세포의 형태에 따른 세포의 부착율은 smooth(55.8%)구가 rough(73.0%)구보다 유의적으로 낮게 나타났으나(p<0.05), clonal line 확립 효율(7.7%n vs. 6.6%) 및 PD(23.5h vs. 24.0h)에서는 차이가 없었다. 본 연구의 결과, 세포의 형태에 따른 cell line 확립 효율은 큰 차이가 없었으나, 세포 배양액내에 30% FBS와 BME의 첨가로 clonal cell line 확립 효율을 향상시킬 수 있음을 확인할 수 있었다. 또한 cell line 확립 효율이 높아질수록 PD 시간이 짧아지는 경향을 볼 수 있었다.

• Journal of Electrical Engineering and Technology
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• v.2 no.1
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• pp.29-34
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• 2007

The input and output impedances in a low voltage distribution system is one of the most important matters for power line communication because from the viewpoint of communication, the attenuation characteristic of the high frequency signals is greatly caused by impedance mismatch during sending and receiving. The frequency range is from 1MHz to 30MHz. Therefore, this paper investigates the input and output impedances in order to understand the characteristic of high frequency signals in the low voltage distribution system between a pole transformer and an end user. For power line communication, the model of Korea's low voltage distribution system is proposed in a residential area and then the low voltage distribution system is set up in a laboratory. In the low voltage distribution system, S parameters are measured by using a network analyzer. Finally, input and output impedances are calculated using S parameters.