• Journal of Korean Society of Rural Planning
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• v.21 no.4
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• pp.139-155
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• 2015

This study was conducted to effectively develop rural tourism in Korea. For the purpose, tourism that can develop with local industries and cultures together was designated as life-type tourism and development models of such tourism were reviewed based on an understanding that province-oriented tourism is necessary. An analysis of three actual cases of Japan led to following results. First, life-type tourist destinations can be developed in connection with making local areas based on their special themes, can be developed in relation to their life cultures based on their peculiar life cultures and can be developed in creative forms using characteristic environment and organizational culture of those areas. In pursuing life-type tourist attractions, it will be possible to make practical development using it with those three basic models. Second, it is important to form a flow covering the entire regions based on their own special themes, to build cyclical structure of regions and tourism and tourism and industries and to create overall conditions that can help local residents get benefits and join together, in order to develop such life-type tourist destinations. Development of life-type resort tourist destinations needs roles of practical organizations that can effectively manage them, but such organizations should be dynamic and should be distant from management of money as much as possible.

• Mycobiology
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• v.50 no.1
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• pp.1-11
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• 2022

The ascomycete fungus Cordyceps militaris infects lepidopteran larvae and pupae and forms characteristic fruiting bodies. Owing to its immune-enhancing effects, the fungus has been used as a medicine. For industrial application, this fungus can be grown on geminated soybeans as an alternative protein source. In our study, we performed a comprehensive transcriptomic analysis to identify core gene sets during C. militaris cultivation on germinated soybeans. RNA-Seq technology was applied to the fungal cultures at seven-time points (2, 4, and 7-day and 2, 3, 5, 7-week old cultures) to investigate the global transcriptomic change. We conducted a time-series analysis using a two-step regression strategy and chose 1460 significant genes and assigned them into five clusters. Characterization of each cluster based on Gene Ontology and Kyoto Encyclopedia of Genes and Genomes databases revealed that transcription profiles changed after two weeks of incubation. Gene mapping of cordycepin biosynthesis and isoflavone modification pathways also confirmed that gene expression in the early stage of GSC cultivation is important for these metabolic pathways. Our transcriptomic analysis and selected genes provided a comprehensive molecular basis for the cultivation of C. militaris on germinated soybeans.

• Journal of Families and Better Life
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• v.15 no.2
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• pp.59-70
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• 1997

As the ancestral rites is one of ritural ceremony in our country it's tradition have performed to-day. The purpose of this research of this research is to study both filial piety as a thought of worshipping ancestors and the traditional ancestral ceremony through examinition of 「kyung-mong-yokyul」provide the basic materials for the practice of the filial piety and contribute to the morals of life and the culture of home life in nodern society. Also through it's litereture it is to research the forms of ancestral ceremony (time place, memorial dress, foods, etc) in the traditional society and the responsibility of acting ancestral rites at home life. According to 「kyung-mong-yokyul」on ancestral rites it stressed on the true heart rather than unrational materialistic courtesy. And the ancestral rites in the family system of traditional socity was the most important things in among practices at home especially the host(the eldest son and the eldest daughter in family) who hol this ceremony played a important roles.

• Journal of the Korean Society of Safety
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• v.14 no.1
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• pp.41-48
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• 1999

The fatigue life tests were performed in strain control with triangular and hole-time wave-forms at $650^{\circ}C$. The fatigue lifes were investigated according to waveform examining damage mechanisms, which could be used to predict the fatigue life and estimate the remaining life. The results obtained are as follows; The fatigue lifes were in order of the fast-fast>the fast-slow>the slow-fast in the triangular waveforms, and the fatigue lifes in slow-fast waveforms got shorter in the hold-time waveforms. The damage mechanisms of the fracture surfaces were transgranular fracture in the fast-fast, the fast-slow waveforms and intergranular fracture in the slow-fast waveform.

• Journal of the Korean Institute of Rural Architecture
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• v.10 no.1
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• pp.11-18
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• 2008

The Geumsan is contiguous to Daejeon and population is decreasing every year. Consequently, the population influx, and securing source of revenue dimensional geographic and environmental benefits of the establishment of a pensions plan for the rural life style pensions research. The result is that Geumsan has a convenient traffic circumstance geographically and is a clean area as the high-level area of solid water system. Also, Geumsan forms the mountainous area whose sea-level elevation reaches to 2.5 times of the Chungcheongnam-do. Consequently, Geumsan has a suitable environment for locating many kinds of pensions like the riverside village style, the mountain village style and the villa style, the country style, the cafe style, experience style, theme style etc. So, Geumsan is found to be a suitable area to host 'rural life style' pensions, because it has wide area, small population and nice environmental conditions.

• Korean Institute of Interior Design Journal
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• v.13 no.2
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• pp.56-63
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• 2004

Harmony between men and their surroundings has been one of the most profound motives in space and object design for a long time. It is often expressed in design as the concept of 'organic'. Nowdays the term of organic is expanding its meaning in the contemporary sense of organicism. Nature, human 'beings, and digital technology are the key issues in future design paradigms. Karim Rashid is one of the most futuristic and vendible designer and his works show these issues. His designs flow organically and he uses materials that allow his forms to flow like the body, echoing life forms. it's very sensual, very tactile. In his work, a new concept of organic design is expressed in the organic unity of experience. He tries to contribute objects to our physical landscape that inspires, engages, and encourage positive experiences. Also, Technology is at constant play in his design process. With the latest three dimensional design software it is much easier to design and model sophisticated and complex shape and forms. Digital technology affects not only his design processes but also cultural views. New technologies and social shifts are changing our understanding of interior space.

• Economic and Environmental Geology
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• v.32 no.3
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• pp.261-271
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• 1999

Mining activity in the Gubong gold mine started in 1908 and lasted up to recent days. Heavy metals derived from the activity may be porentially toxic to human life and envirinment of this area. Because metal toxicity depends on chemical associations into five operationally defined groups: exchangeable, carbonate, reducible, oxidizable, and residual fractions, and the Most of heavy metals have significant little significance (alomost<1%). And Cu is mainly associated with the oxidizable from. Total concentration of heavy metals, pH, and mineralogy affect the chemical forms of the metals. Heavy metal concentrations. Significant amounts of metal elements (5∼65.1% in Pb, 6.2∼39.7% in Zn, 8.7∼54.7% in Cd, and 3.6∼24.7% in Cu) were present in carbonate form from mine wastes, contaminated soils and sediments. High pH value and cerussite (Pb bearing carbonate mineral) in mine wastes, contaminated soils and sediments. High pH value and cerussite (Pb beraring varbonate mineral) in mine waste support this result. Areas with high corbonate bound from would have higher potentoal conamination, however, because elements of carbonate bound forms are easily mobilized under lower pH conditions in the surface envionments due to acid to rain soil acidification.

• Reproductive and Developmental Biology
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• v.36 no.3
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• pp.193-198
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• 2012

This study was to examine expression of the recombinant full-length adiponectin (recombinant adiponectin) in insect ovarian cell culture system and to characterize structural properties of the recombinant adiponectin secreted in medium. Gene construct encoding the recombinant adiponectin contained N-terminal collagen-like domain (110 Amino Acids, AAs), C-terminal globular domain (137 AAs) and C-terminal peptides for detection with V5 antibody (26 AAs included adaptor peptide) and purification using the 6xHis tag (6 AAs). The approximate molecular weight of the product (monomer) was 35 kDa. Molecular mass species of the expressed recombinant adiponectin were monomer (~35 kDa), dimer (~70 kDa), trimer (~105 kDa) and hexamer (~210 kDa). The major secreted species were the LMW forms, such as monomer, dimer, and trimer. There was MMW of hexamer as minor form. HMW multimers (~300 kDa) were shown as a tracer or not detected on the SDS-PAGE in several experiments (data not shown). The multimer forms in this study were not compatible to those in animal or human serum and adipose tissue by other researcher's study in which the major multimer forms were HMW. By protein denaturing experiments with reducing reagent (${\beta}$-MeOH), anionic detergent (SDS) and heat ($95^{\circ}C$) on the SDS-PAGE, not all adiponectin multimers seemed to have disulfide bond linked structure to form multimers. The recombinant adiponectin which expressed in insect ovarian cell culture system seemed to have the limitation as full physiological regulator for the application to animal and human study.

• Journal of the Korean housing association
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• v.24 no.6
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• pp.123-132
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• 2013

This study covers centrality of villas after Renaissance and architectural forms corresponding to the nature in the aspect of Karl Popper and Gilles Deleuze. In addition, the researcher tries to understand the changes in architectural forms according to the changes in places. To do that, Pascal and Hans Meyer's theory was introduced as a major theory. The researcher tries to set up the standard by analyzing the architectural form related with the nature and the form of center in the housing through Villa Rotonda and Villa Emo. And with key analysis of the centrality and architectural form corresponding to the nature and the four houses that are historically and morphologically important. It is found that due to the development in modern technology and materials, a variety of architectural approach is developed and they are implemented as various architectural forms. However, due to various theories of modern architectural approach, it is found that the morphological differences of suburban housing exists by forming a universal relationship constructed by four architects. The researcher expects to be understood and realized in real life construction.

• BMB Reports
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• v.43 no.5
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• pp.305-310
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• 2010

Syndecans, cell surface heparansulfate proteoglycans, have been proposed to act as cell surface receptors and/or coreceptors to play critical roles in multiple cellular functions. However, recent reports suggest that the function of syndecans can be further extended through shedding, a cleavage of extracellular domain. Shedding constitutes an additional level for controlling the function of syndecans, providing a means to attenuate and/or regulate amplitude and duration of syndecan signals by modulating the activity of syndecans as cell surface receptors. Whether these remaining cleavage products are still capable of functioning as cell surface receptors to efficiently transduce signals inside of cells is not clear. However, shedding transforms cell surface receptor syndecans into soluble forms, which, like growth factors, may act as novel ligands to induce cellular responses by association with other cell surface receptors. It is becoming interestingly evident that shed syndecans also contribute significantly to syndecan functions in cancer biology. This review presents current knowledge about syndecan shedding and its functional significance, particularly in the context of cancer.