• 동의생리병리학회지
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• 제23권3호
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• pp.715-722
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• 2009

The aim of this study was to investigate the safety of short-term use of Korean herbal medicine (KHM; prescribed herbal medicine by doctors of traditional Korean medicine) on liver function. Three hundred eighty four outpatients who took KHM for various conditions were enrolled for multi-center, prospective observational study. Of them 237 patients completed questionnaire and were checked liver function (aspartic aminotransferase;AST, alanine aminotransferase;ALT, alkaline phosphatase;ALP, total bilirubin;t-Bil, direct bilirubin;d-Bil, gamma glutamyltranspeptidase;GGT, protein and albumin) before and after taking KHM (duration; 21.4${\pm}$10.0 days), and data were analysed statistically. Of the 213 patients showing normal liver function test (LFT) at baseline, 209 (98.1%) remained within the normal range at the second test while 3 (1.4%) revealed slight increase of LFT. Only one subject had raised LFT regarding level of liver injury without perceived symptoms. Twenty-four of 237 patients were abnormal at baseline, and 16 at the second testing. Of the patients taking KHM, only 4 changed from normal to abnormal while 12 from abnormal to normal in their LFT. There were no significant increase in LFT level between the first and second test, except in the t-Bil level, however, the change of t-Bil was small and within normal range. The current study showed that the use of KHM did not increase the frequency of abnormal LFTs, at least in the short term.

• 한국산학기술학회논문지
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• 제12권4호
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• pp.1982-1987
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• 2011

본 연구에서는 미지시료 또는 LFT와 같은 고점도 수지의 점도를 실제 사출성형 공정과 CAE 해석을 통하여 신뢰할 수 있는 새로운 점도의 추정 방법을 제안하였다. 우선 금형 내에 캐비티 압력을 측정할 수 있는 시스템을 구성하였고, 이 시스템을 이용해서 실제 사출과정에서 나타나는 압력 변화를 측정하는 것이다. 상용화 된 CAE 프로그램(Moldflow)은 사출공정에서 캐비티 내부를 흐르는 수지의 압력변화를 모사할 수 있다. 만약, CAE D/B에 있는 수지의 점도 데이터가 정확하다고 가정하면, 실험에서 측정한 압력 프로파일과 CAE로부터 계산 된 압력 프로파일이 일치해야 한다. 이것이 실험값과 일치하지 않으면 가정한 값을 CAE D/B에 입력해서 일치할 때까지 반복함으로써 신뢰성 있는 점도를 추정 할 수 있다. 이러한 알고리즘의 타당성을 검증하기 위해서 PP수지에 대하여 적용한 결과, 일반적인 점도계로 측정한 값과 일치하는 결과를 얻었다. 한편, PP-LFT에 대하여 적용하여 최적화 된 점도 데이터도 추정할 수 있었다.

• 한방비만학회지
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• 제10권1호
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• pp.29-40
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• 2010

Objective The aim of this study was to evaluate the influence of Gamitaeeumjowi-tang(GTT) prescribed by doctors of korean(KMD) medicine on liver function. Methods For this single-center, prospective, observational study, we enrolled patients who wished to take GTT prescribed by KMD for losing weight. sixty(60) patients took GTT for 33.8 days and completed questionnaires. Liver function tests(LFTs) were performed bofore(first test) and after each GTT treatment(finish test). For LFT, T-bil, ALP, AST, ALT were measured. Result There were no significant changes in LFT data between the first and finish tests. At first test, levels of test seven(7) patients were more than twice of normal range of upper limit, levels of eight(8) patients were more than normal range of upper limit, less than twice of normal range of upper limit. At last test, levels of nine(9) patients were more than normal range of upper limit, less than twice of normal range of upper limit. Conclusion The current study showed that ingestion of GTT prescribed by KMD did not increase the frequency of abnormal LFTs, at least in the short term.

• 지식경영연구
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• 제9권1호
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• pp.77-96
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• 2008

The purpose of this study is to find the new model of successful social enterprise on the basis of local economy and industry in Korea. The trends and definitions of social enterprise were discussed first of all and community business model operated by civilians and members of a community was studied. The community business of local friendly type(LFT) was focused especially. Some factors of LFT are such as the solution of economic polarization and employment aggravation, the recovery of local community, the solution of local problem, and new method of labor contract. As the result of exploratory analysis on community business in Korea, Some distinctive features were showed that the majority of business was managed by local government, the outcomes of local community business were improvement of local income and creation of employment. Also, there were barriers such as finance, marketing, and lack of entrepreneurship. In conclusion, community business enterprise on the basis of local is effective to develop local economy and it should be owned by local civilians. In addition, long-term aims, entrepreneurship, and positiveness need for making of local society wealth.

• 대한한의학회지
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• 제33권3호
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• pp.95-104
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• 2012

Objectives: There are some controversies over the safety of herbal medication in relation to liver function. This report, therefore, aimed to analyze the safety issue of herbal medications by scrutinizing the liver function tests (LFT) results of 82 psoriasis patients on herbal medications for 3 months at an oriental medical clinic. Methods: We tested psoriasis patients' liver function periodically with Reflotron Plus of Roche during the herbal medication. Then we statistically analyzed the LFT results to see if there was any negative change. Results: Statistical analysis on the LFT results of 82 psoriasis patients showed no meaningful change caused by herbal medication over 3 months. Conclusions: From this result we conclude that herbal medication for 3 months does no harm to patients' liver function.

• 월간피드저널
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• 제5권4호통권44호
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• pp.142-145
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• 2007

• 대한약침학회지
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• 제13권2호
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• pp.67-73
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• 2010

Objective : The purpose of this study is to determine the efficacy and safely of Hwangryunhaedok-tang Pharmacopuncture (HHT-PA) therapy on post-stroke depression (PSD) in stroke patients. Methods : Fifteen PSD patients has been recruited and evaluated with liver function test (LFT) and renal function lest (RFT) and depression scales, Beck Depress ion Inventory (BDI) and Hamilton Depression Rating Scale (HAM-D) before and after HHT-PA treatment. Results : HAM-D score significantly decreased after HHT-PA treatment regard less of improving of motor function. But BDI score did not decrease significantly. All results of LFT and RFT were in normal range before and after HHT-PA treatment Conclusion : These results showed that HHT-PA decrease PSD symptoms and has safety on stroke patients, although has no effect on improving of motor impairment.

• International Journal of Control, Automation, and Systems
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• 제6권2호
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• pp.171-179
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• 2008

This paper addresses the synthesis of an iterative learning controller for a class of linear systems with norm-bounded parameter uncertainties. We take into account an iterative learning algorithm with current cycle feedback in order to achieve both robust convergence and robust stability. The synthesis problem of the developed iterative learning control (ILC) system is reformulated as the ${\gamma}$-suboptimal $H_{\infty}$ control problem via the linear fractional transformation (LFT). A sufficient convergence condition of the ILC system is presented in terms of linear matrix inequalities (LMIs). Furthermore, the ILC system with fast convergence rate is constructed using a convex optimization technique with LMI constraints. The simulation results demonstrate the effectiveness of the proposed method.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1981년도 제20차 춘계학술대회 및 총회
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• pp.124.1-124.1
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• 1981

• Composites Research
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• 제33권6호
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• pp.383-389
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• 2020

열가소성 복합재료를 적용하여 자동차 도어 임팩트 빔을 설계하고 시생산을 통해 생산성 및 성능을 검증하였다. 자동차 안전법규는 지속적으로 강화되어 왔으며 최근 자동차 산업에서 경량화가 필수 요건이 되면서 고성능 경량 부품에 대한 요구가 크게 증대되고 있다. 본 연구는 섬유강화 열가소성 복합소재를 도입하여 기존 탄소강 제품 대비 경량화 되면서 성능은 향상된 도어 임팩트 빔 개발을 목표로 하였다. 연속섬유 복합재료와 장섬유 복합재료(LFT)를 혼합 적용한 도어 임팩트 빔 제작 공정을 제시하며, 생산성이 우수한 인서트 사출 공정을 활용하여 구현하였다. 시생산된 도어 임팩트 빔은 3점 굽힘 시험을 통하여 성능을 평가하였다. 열가소성 복합재료는 경량화 설계와 함께 높은 생산성 구현이 가능하여 다양한 자동차 부품으로 복합소재의 적용을 확대시킬 것이다.