• Title/Summary/Keyword: LCT

Search Result 62, Processing Time 0.029 seconds

Effects of intermittent ladder-climbing training on neurobiological markers in mice with type 2 diabetes

  • Shin, Ki-Ok;Woo, Jinhee;Park, Chan-Ho;Yoon, Byung-Kon;Kim, Do-Yeon;Roh, Hee-Tae
    • Journal of the Korean Applied Science and Technology
    • /
    • v.37 no.4
    • /
    • pp.762-768
    • /
    • 2020
  • This study aimed to investigate the effect of ladder-climbing exercise training on neurobiological markers in the hippocampus of mice with type 2 diabetes (T2DM). Twenty-one C57BL/6 male mice were randomly assigned to the non-diabetic control (NDC, n = 7), diabetic control (DC, n = 7), and diabetic training (DT, n = 7) groups. The DT group performed ladder-climbing training (LCT) five times a week for eight weeks. We measured the levels of hippocampal neurobiological markers (catalase [CAT], brain-derived neurotrophic factor [BDNF], nerve growth factor [NGF], amyloid-beta [Aβ], tau, and CC motif chemokine ligand 11 [CCL11]). The BDNF levels were significantly higher in the DT group than in the DC group (p < 0.05). The Aβ and CCL11 levels were significantly higher in the DC group than in the NDC and DT groups (p < 0.05). The tau levels were significantly higher in the DC group than in the NDC group (p < 0.05). However, there was no significant difference in CAT and NGF levels among the groups (p > 0.05). These results suggest that while T2DM could induce neurodegeneration, LCT may be effective in alleviating neurodegeneration caused by T2DM.

Development of LDV(Laser Doppler Velocimetry) for Measuring Three Dimensional Hull Wake of Ship Model in Large Cavitation Tunnel (대형 캐비테이션 터널 내 선박 모형의 3차원 선체 반류 계측을 위한 레이저 유속계 개발)

  • Paik, Bu-Geun;Ahn, Jong-Woo;Seol, Han-Shin;Park, Young-Ha;Kim, Ki-Sup;Cheon, Ho-Geun
    • Journal of the Society of Naval Architects of Korea
    • /
    • v.54 no.6
    • /
    • pp.515-521
    • /
    • 2017
  • Large Cavitation Tunnel (LCT) of KRISO enables us to conduct cavitation tests of the propeller attached to a ship model. As the ship model tests are done at rather high Reynolds number of 107~108, flow measurement system such as pitot tube cannot be employed because of structural safety problems in its system and difficulties in installing it within the test section. Thus, KRISO has developed new 3-D LDV system used in large test section of LCT. There are several difficulties in using 3-D LDV, which did not allow efficient operation of it. The first trouble was the calibration using the conventional pin hole. To make the focus with same laser-beam waists at the wanted position, the high spatial resolution CCD is utilized in the calibration procedure for 3-D LDV. The off-axis configuration provides two velocity components in the horizontal plane and on-axis configuration gives third velocity component in the vertical plane. The horizontal velocity components are also obtained in the coincidence mode, which prevents any misleading results in the off-axis configuration. The nominal wake of Aframax tanker model is measured by the developed 3-D LDV system. The measured hull wake showed good agreement with that obtained by CFD calculation.

The Effects of Educational Contents Authoring in a Project-Based Learning using NetLogo for Pre-service Teachers' Creativity (PBL 기반의 NetLogo를 이용한 교육용 콘텐츠 저작이 예비중등교사의 창의성에 미치는 효과)

  • Kim, Jin-Young;Park, Hong-Joon;Jun, Young-Cook
    • Journal of Engineering Education Research
    • /
    • v.14 no.4
    • /
    • pp.29-38
    • /
    • 2011
  • The objective of this study is the analysis of the effects of educational contents authoring in a PBL using NetLogo Pre-service teachers' creativity. With utilization of the analysis, we attempted to draw implications on the factors considered in instructional design. To compare their creativity before and after class, we have done pre-service teachers test for each Pre- and Post- TTCT and LCT. Based on the analysis, as a result, there has been a significant improvement in their creativity, most especially in the 'fluency' subcategory.

Influence of modification in core building procedure on fracture strength and failure patterns of premolars restored with fiber post and composite core

  • Kim, Young-Hoi;Lee, Jong-Hyuk
    • The Journal of Advanced Prosthodontics
    • /
    • v.4 no.1
    • /
    • pp.37-42
    • /
    • 2012
  • PURPOSE. The influence of the modified process in the fiber-reinforced post and resin core foundation treatment on the fracture resistance and failure pattern of premolar was tested in this study. MATERIALS AND METHODS. Thirty-six human mandibular premolars were divided into 4 groups (n = 9). In group DCT, the quartz fibre post (D.T. Light-post) was cemented with resin cement (DUO-LINK) and a core foundation was formed with composite resin (LIGHT-CORE). In group DMO and DMT, resin cement (DUO-LINK) was used for post (D.T. Lightpost) cementation and core foundation; in group DMO, these procedures were performed simultaneously in one step, while DMT group was accomplished in separated two steps. In group LCT, the glass fiber post (LuxaPost) cementation and core foundation was accomplished with composite resin (LuxaCore-Dual) in separated procedures. Tooth were prepared with 2 mm ferrule and restored with nickel-chromium crowns. A static loading test was carried out and loads were applied to the buccal surface of the buccal cusp at a 45 degree inclination to the long axis of the tooth until failure occurred. The data were analyzed with MANOVA (${\alpha}$= .05). The failure pattern was observed and classified as either favorable (allowing repair) or unfavorable (not allowing repair). RESULTS. The mean fracture strength was highest in group DCT followed in descending order by groups DMO, DMT, and LCT. However, there were no significant differences in fracture strength between the groups. A higher prevalence of favorable fractures was detected in group DMT but there were no significant differences between the groups. CONCLUSION. The change of post or core foundation method does not appear to influence the fracture strength and failure patterns.

Prediction of the Effective Wake of an Axisymmetric Body (축대칭 몰수체의 유효반류 추정)

  • Kim, Ki-Sup;Moon, Il-Sung;Ahn, Jong-Woo;Kim, Gun-Do;Park, Young-Ha;Lee, Chang-Sup
    • Journal of the Society of Naval Architects of Korea
    • /
    • v.56 no.5
    • /
    • pp.410-417
    • /
    • 2019
  • An axisymmetric submerged body(L=5.6m, Diam=0.53m) is installed in Large Cavitation Tunnel (LCT) of KRISO and the nominal and total velocities without and with the propeller in operation, respectively, are measured using Laser Doppler Velocimeter (LDV). The flow field is nearly axisymmetric except the wake of the supporting strut, and is considered ideal to study the hydrodynamic interaction between the propeller and the oncoming axisymmetric sheared flow. The measured velocity data are then provided to compute the propeller-induced velocity to get the effective velocity, which is defined by subtracting the propeller-induced velocity from the total velocity. We adopted, in computing the induced velocity, two different methods including the vortex lattice method and the vortex tube actuator model to evaluate the resultant effective velocity distribution. To secure a fundamental base of experimental data necessary for the research on the effective wake, we measured the drag of the submerged body, the nominal and total velocity distributions at various axial locations for three different tunnel water speeds.

Fumigant Activity of Phosphine Against Three Wood Boring Beetles, Platypus koryoensis, Cryphalus fulvus, and Xyleborus mutilatus (광릉긴나무좀, 왕녹나무좀, 노랑애나무좀 성충에 대한 포스핀의 훈증활성)

  • Cho, Sung Woo;Kim, Sung Il;Kim, Hyun Kyung;Kim, Gil-Hah
    • Korean journal of applied entomology
    • /
    • v.58 no.1
    • /
    • pp.31-35
    • /
    • 2019
  • Many forest pests have caused problems for wood quarantine. The fumigation activity of phosphine ($PH_3$) was examined for the adults of three wood-boring insect pests. The $LCT_{99}$ values for Platypus koryoensis, Cryphalus fulvus, and Xyleborus mutilates were 3.192, 0.994, and $0.501mg{\cdot}h/L$ at $20^{\circ}C$, respectively. The effectiveness of $PH_3$ was increasingly time dependent for all doses tested in all three species. In particular, P. koryoensis showed 100% mortality at doses higher than 0.4 mg/L 7 days after fumigation. These results indicate that methyl bromide could be substituted for $PH_3$ for adults of these three species of wood pest.

Study of the Propeller Cavitation Performance Improvement Through the Stern Appendage Modification (선미 부가물 수정에 따른 프로펠러 캐비테이션 성능 향상 연구)

  • Jong-Woo Ahn;Young-Ha Park;Gun-Do Kim;Bu-Geun Paik;Han-Shin Seol;Il-Ryong ParK
    • Journal of the Society of Naval Architects of Korea
    • /
    • v.60 no.1
    • /
    • pp.1-9
    • /
    • 2023
  • In order to improve the propeller cavitation performance composed of Cavitation Inception Speed (CIS), cavitation extent and pressure fluctuation, it needs to improve the wake distribution that flows into the propeller. The warship propeller cavitation is strongly influenced by the wake created at the V-strut of various appendages. The inflow characteristics of the V-strut were investigated using Computational Fluid Dynamics (CFD) and the twisted angles of the V-strut were aligned with upstream flow. The resistance and self-propulsion tests for the model ship with the existing and modified V-struts were conducted in Towing Tank (TT), and wake distribution, CIS, cavitation observation and pressure fluctuation tests were conducted in Large Cavitation Tunnel (LCT). The propeller behind the modified V-strut showed better cavitation characteristics than that behind the existing V-strut. Another model test was conducted to investigate rudder cavitation performance by the change of the V-strut. The rudder cavitation characteristics were not improved by the change of the operating conditions. On the basis of the present study, it is thought that the stern appendages for better propeller cavitation performance would be developed.

Implementation and evaluation of reliable multicast protocol with the ALC and LDPC FEC over wireless LAN environment (무선 LAN 환경에서 ALC와 LDPC FEC를 이용한 신뢰적인 멀티 캐스트 전송 프로토콜의 구현 및 성능 평가)

  • Paik Il-Woo;Seong Baek-Dong;Hong Jin-Pyo
    • Proceedings of the Korean Information Science Society Conference
    • /
    • 2006.06d
    • /
    • pp.250-252
    • /
    • 2006
  • ALC(Asyncronous Layered Coding)는 LCT(Layered Coding Transport)기반의 폭넓은 확장성과 다양한 전송속도로 신뢰성 있는 멀티캐스트 전송을 주 목적으로 한다. ALC는 다른 RMT 프로토콜과는 달리 재전송을 하지 않고 receiver-driven 형태의 혼잡제어를 하기 때문에 신뢰성을 제공하기 위해 FEC(Forward Error Correction) 스킴를 이용한다. 본 논문은 신뢰적인 멀티캐스트 전송 프로토콜을 위해 ALC와 FEC 스킴 중 하나인 LDPC 코드를 이용하여 구현한다. 인코딩 비율(Encoding ratio)에 따라 일정 수준 이상의 복구 성공 확율에 대해 최대 허용 가능한 패킷 손실률을 측정하여 신뢰치를 측정한다. 마지막으로 일대다의 파일 전송 시, TCP와 비교하여 본 구현물의 유연성과 효율성에 대해 분석 및 평가한다.

  • PDF

A Study of Clinical Application of the Connective Tissue Massage. (결합조직마사지의 임상적 적용연구)

  • Lim Weon-Sik;Kim Jae-Yoon;Jung Yeon-Woo
    • The Journal of Korean Physical Therapy
    • /
    • v.14 no.3
    • /
    • pp.345-354
    • /
    • 2002
  • A Study of Clinical Application of the Connective Tissue Massage General massage is termed kneading and rubbing. It will bring the effect of blood volume and cardiovascular reaction. Connective tissue massage is a diagnostic and treatment method. But the general massage has not diagnostic aspect. Connective tissue massage techniques are stimulating and stretching the LCT, mast cell, collagenous fiber, fascia, skin, muscle and nerve tissue. Diagnostic aspects of connective tissue massage are visible investigation, manual investigation, and stroking on the reflex zone. CTM do stroking with 3, 4th finger tips on the whole body for the treatment.

  • PDF

PRICING AMERICAN LOOKBACK OPTIONS UNDER A STOCHASTIC VOLATILITY MODEL

  • Donghyun Kim;Junhui Woo;Ji-Hun Yoon
    • Bulletin of the Korean Mathematical Society
    • /
    • v.60 no.2
    • /
    • pp.361-388
    • /
    • 2023
  • In this study, we deal with American lookback option prices on dividend-paying assets under a stochastic volatility (SV) model. By using the asymptotic analysis introduced by Fouque et al. [17] and the Laplace-Carson transform (LCT), we derive the explicit formula for the option prices and the free boundary values with a finite expiration whose volatility is driven by a fast mean-reverting Ornstein-Uhlenbeck process. In addition, we examine the numerical implications of the SV on the American lookback option with respect to the model parameters and verify that the obtained explicit analytical option price has been obtained accurately and efficiently in comparison with the price obtained from the Monte-Carlo simulation.