• BMB Reports
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• 제49권8호
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• pp.424-430
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• 2016

Autophagy, an evolutionarily conserved cellular degradation pathway of the lysosome, is associated with many physiological and pathological processes. The hallmark of autophagy is the formation of the autophagosome that engulfs and degrades cytosolic components via its fusion with the lysosome, in either a selective or a non-selective manner. Autophagy is tightly regulated by proteins encoded by autophagy-related (atg) genes. Among these proteins, ATG8/LC3 is essential for autophagosome biogenesis/maturation and it also functions as an adaptor protein for selective autophagy. In mammalian cells, several homologs of yeast Atg8 such as MAP1LC3, GABARAP, and GABARAPL 1/2 have been identified. However, the biological relevance of this gene diversity in higher eukaryotes, and their specific roles, are largely unknown. In this review, we describe the mammalian ATG8/LC3 family and discuss recent advancements in understanding their roles in the autophagic process.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.1139-1143
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• 2015

In order to explore the association between cadherin 13 (CDH13) gene promoter methylation and lung carcinoma (LC) risk, we carried out a meta-analysis with searching of PubMed, Web of Science. Ultimately, 17 articles were identified and analysised by STATA 12.0 software. Overall, we found a significant relationship between CDH13 promoter methylation and LC risk (odds ratio=6.98, 95% confidence interval: 4.21-11.56, p<0.001). Subgroup analyses further revealed that LC risk was increased for individuals carrying the methylated CDH13 compared with those with unmethylated CDH13. Hence, our study identified a strong association between CDH13 gene promoter methylation and LC and highlighted a promising potential for CDH13 methylation in LC risk prediction.

• 한국전기전자재료학회논문지
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• 제17권5호
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• pp.536-540
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• 2004

A novel nematic liquid crystal (LC) cell with splay structure exhibiting wide viewing angle, fast response time and high transmittance at the same time has been developed. With rubbed homeotropic alignment in parallel directions, the device shows bend alignment in the absence of vertical electric field. However, with applied high voltage in a pulse form, the LC shows a optically compensated splay (OCS) orientation such that the mid-director is parallel to a substrate and at both surfaces the LCs are aligned vertically in parallel direction. In the device, the birefringence of the cell becomes tunable with applying voltage, i.e., the amount of light passed through the cell can be controlled by controlling the orientation of the LC. Since the OCS cell has a self-compensation structure such that the LC has a mirror symmetry along the mid-director, the device shows a wide viewing angle with only a single domain and a fast response time.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2005년도 International Meeting on Information Displayvol.I
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• pp.571-574
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• 2005

We demonstrated a high speed liquid crystal (LC) display mode based on a nonchiral smectic C LC in an antiparallel planar geometry. In this antiparallel planar nonchiral smectic C (APNSC) LC mode, analog gray scales and wide viewing properties are achieved using a stepwise thermal annealing process (STAP). Because of an initially stable LC alignment in large area through the STAP, the APNSC LC mode exhibits the characteristics of fast response and high contrast ratio. This new APNSC mode is suitable for processing the dynamic image at a video rate in the next-generation LCDs.

• 한국전기전자재료학회논문지
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• 제16권11호
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• pp.1014-1018
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• 2003

A photoalignment material of a PGMAcr, poly[3-(acryloyloxy)-2-hydroxypropyl methacrylate] using a photopolymerized the acrylate unit by photo-initiator and a PGMA4Ch, poly[3(4-chalconyloxy)-2-hydroxypropyl methacrylate] using a photodimerization by chalcone group were synthesized. Also, the liquid crystal (LC) aligning capabilities on the photopolymer layers were studied. A good LC alignment with UV exposure on the PGMAcr surface can be obtained. However, the LC alignment defects were observed on the PGMA4Ch surface. The LC aligning capabilities of the PGMAcr surface by photo-initiator were better than that of the PGMA4Ch surface by chalcone group as photosensitive moiety.

• 연구논문집
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• 통권33호
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• pp.167-174
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• 2003

Alloy 713LC was developed to improve the tensile strength and ductility by reducing the carbon content of Alloy 713C. As Alloy 713LC was designed to minimize the mechanical property change with process conditions, it is generally utilized in the parts which have thick and thin sections simultaneously. In the thick and the thin sections, quite different properties are required. Consequently it is essential to crucially control the local mechanical properties of a parts by optimizing the process condition and heat treatment. In this research, high temperature mechanical properties including creep-rupture and strain-control low cycle fatigue were investigated together with the microstructural variations with heat treatment. Failure mechanism was also analyzed by observing the fracture surface to correlate the variation of mechanical properties with the microstructural change.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2002년도 춘계종합학술대회
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• pp.535-539
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• 2002

본 논문에서는 Hybrid SC/MRC-Lc/L 다이버시티 수신 기법과 콘볼루션 부호화 기법을 각각 또는 함께 이용할 때의 Multi-Carrier DS-CDMA 시스템의 성능 개선을 구하였다. 우선 다중경로 페이딩 및 다중접속간섭의 영향을 분석하고, 두 기법에 의한 성능 개선 정도를 구하여 비교, 분석하였다. Hybrid SC/MRC-Lc/L 수신에서는 각각의 반송파에 대하여 상관을 취하고 상관기 출력들 중에서 가장 큰 신호성분을 Lc개만큼 선택하여 최대비 합성하며, 콘볼루션 부호화는 다중경로 페이딩 및 다중접속간섭에 의하여 발생된 오류를 정정 및 검출한다. 분석 결과, 콘볼루션 부호화 기법을 채용함으로서 성능이 현저하게 개선되는데, 부호이득과 전력제한 사이에 trade off를 고려하여 부호화 율( r)을 선택할 필요가 있다는 것과 하이브리드 SC/MRC-L$^{c}$ /L 수신에서는 입력 다이버시티 가지의 수 (L)가 많을수록 선택의 폭이 넓어지며, 적절한 숫자의 다이버시티 가지의 선택이 시스템의 복잡성과 성능 대 비용 등을 결정한다는 것을 알 수 있었다.

• 전기학회논문지
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• 제61권12호
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• pp.1877-1879
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• 2012

Generally, stray capacitance is unnecessary element of designing circuit, because it can not be predicted by a designer. But we propose LC Resonant Circuit using stray capacitance of transformer. This method proposes miniaturization of circuit, because LC Resonant Circuit can be make simply to using stray capacitance instead of capacitor and size of transformer is reduced. Finally, we research aspect of dielectric heating by change of frequency and output voltage using developed converter.

• Transactions on Electrical and Electronic Materials
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• 제7권6호
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• pp.305-308
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• 2006

We have studied liquid crystal (LC) aligning capabilities for homeotropic alignment and the control of tilt angles on the $SiO_{x}$ thin film by electron beam evaporation method. A high tilt angle of about $86.5^{\circ}$ was obtained, and also the suitable tilt angle of the NLC on the $SiO_{x}$ thin film at $20{\sim}50\;nm$ thickness with e-beam evaporation can be achieved. The uniform LC alignment on the $SiO_{x}$ thin film surfaces with electron beam evaporation can be achieved. It is considerated that the LC alignment on the $SiO_{x}$ thin film by electron beam evaporation is attributed to elastic interaction between LC molecules and micro-grooves at the $SiO_{x}$ thin film surface created by evaporation.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1993년도 하계학술대회 논문집 B
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• pp.631-635
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• 1993

This paper shows the procedure to determine the physical variables of the simple synthetic testing facility using LC resonance circuit and presents the calculated results of those variables for the LC resonance circuit which can be used to test circuit breakers up to 36kV 40kA class. Attention has also been paid to the advantages of the LC resonance circuit compared with the method adopting short-circuit generator for the development of circuit breakers.