• Clinical and Experimental Reproductive Medicine
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• 제26권2호
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• pp.185-192
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• 1999

The present study was performed to investigate the efficacy and safety of laser assisted hatching (AH) on mouse embryos. Non-contact $1.48{\mu}m$ diode laser system used to create a precise hole on zona pellucida. 2-cell embryos were collected from the mice (ICR) that had the coitus vaginal plug confirmed at 48 hours after hCG injection. Collected 2-cell embryos were cultured in the HTF medium supplemented with 0.4% BSA. For experiments, embryos at 8-cell stage were used after 18-22 hours in culture. After assisted hatching, the embryos were further cultured in HTF medium containing 0.1% PVP (anti-hatching system) for 3 days. For evaluate efficiency of laser on mouse embryo hatching, the effect of AH methods (acidic tyrode, pronase and laser), the number of artificial holes (1, 2 and 3 hole) and the irradiation time of laser (2, 4, 6, 8 and 10 ms) were examined. Hatching rates of laser AH group (95.2%) was significantly higher than that of control group (50.8%), but there was no differences among the laser (95.2%), acidic tyrode (100%) and pronase (98.5%) groups. Hatching rates of the number of zona pellucida opening by laser, there were no differences among the 1 hole (87.5%),2 hole (92.1%) and 3 hole (85.9%) groups. Developmental and hatching rates of embryos according to laser irradiation time were similar in the treatment groups. Therefore, these results suggest that laser AH using non-contact $1.48{\mu}m$ diode laser is a simple and accurate and effective procedure for AH. Based on these results, laser AH could be use safely for human ART program.

• 한국광학회지
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• 제11권6호
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• pp.379-384
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• 2000

레이저 냉각법을 이용하여 세슘 원자의 온도를 도플러 냉각 한계온도 보다 낮은 온도까지 냉각하였다. 자기-광 포획된 원자를 더 냉각하기 위해서는 냉각용 레이저의 주파수를 더 적색편이 시켜야 하는데, 이를 위해 본 연구에서는 세슘 원자 흡수선의 Zeeman 이동을 이용하였다. 이 방법으로 레이저 주파수 안정화를 유지하면서 레이저의 주파수를 약 40MHz 만큼 이동시킬수 있었다. 비행시간 방법으로 측정한 레이저 냉각된 세슘원자의 최저온도는 $2.2\muK$\pm$0.5$\muK$이었다. 냉각된 원자의 온도를 레이저의 주파수 및 세기에 따라 측정하였는데, 이광자 냉각 이론에 의한 계산결과와 잘 일치한다는 것을 알았다.

• ETRI Journal
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• 제35권3호
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• pp.459-468
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• 2013

A novel integrated laser, that is, a distributed reflector laser diode integrated with an electroabsorption modulator, is proposed to improve the output efficiency, single-mode stability, and chirp. The proposed laser can be realized using the selective metalorganic vapor phase epitaxy technique (that is, control of the width of the insulating mask), and its fabrication process is almost the same as the conventional electroabsorption modulated laser (EML) process except for the asymmetric coupling coefficient structure along the cavity. For our analysis, an accurate time-domain transfer-matrix-based laser model is developed. Based on this model, we perform steady-state and large-signal analyses. The performances of the proposed laser, such as the output power, extinction ratio, and chirp, are compared with those of the EML. Under 10-Gbps NRZ modulation, we can obtain a 30% higher output power and about 50% lower chirp than the conventional EML. In particular, the simulation results show that the chirp provided by the proposed laser can appear to have a longer wavelength side at the leading edge of the pulse and a shorter wavelength side at the falling edge.

• Journal of the Optical Society of Korea
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• 제19권4호
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• pp.363-370
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• 2015

The current waveform model of a laser altimeter is based on a Gaussian laser beam of fundamental mode, while the flattened Gaussian beam has many advantages such as nearly constant energy distribution on the center of the cross-section. Following the theory of the flattened Gaussian beam and the waveform theory of the laser altimeter, some of the primary parameters of the received waveform were derived, and a laser altimetry waveform simulator and waveform processing software were programmed and improved under the circumstance of a flattened Gaussian beam. The result showed that the bias between theoretical and simulated waveforms was less than 3% for every order mode, the waveform width and range error would increase as target slope or order number rose. Under higher order mode, the shapes of the received waveforms were no longer Gaussian, and could be fitted more precisely as a generalized Gaussian function with power bigger than 2. The flattened beam got much better performance for a multi-surface target, especially when the small surface is far from the center of the laser footprint. This article provides the waveform theoretical basis for the use of a flattened Gaussian beam in a laser altimeter.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2009년도 하계학술대회 논문집
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• pp.411-411
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• 2009

Low level laser therapy has various therapy effects. This paper performed the basic study for developing the Low Level Laser Therapy Equipment for medical treatment. The apparatus has been fabricated using the laser diode and microprocessor unit. This equipment was fabricated using a micro-controller and a laser diode, and designed to enable us to control light irradiation time, frequency and so on. In this study, the designed device was used to find out how infrared laser diode affected the collagen formation. For in-vivo test, a round wound 1cm in diameter was cut from the test animal whose epidermal and dermal layers were removed. Test animals were relieved for 24 hours after wounds had been excised and then the infrared laser irradiation group was given irradiation therapy over 9 days one 20 min per day. As a result, More collagenosis occurred in the order of infrared laser irradiation and non-irradiation group. Collagenosis is closely related to wound repair and it was found that infrared laser irradiation groups had more collagenosis and was quicker to recover from wound than non-irradiation group.

• Journal of Advanced Marine Engineering and Technology
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• 제33권2호
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• pp.322-329
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• 2009

Machinability of LAM(Laser Assisted Machining) has been studied for ceramics such as $Al_2O_3$, $Si_3_N4$ and $ZrO_2$ by $CO_2$ laser. It was possible to remove ceramics by PCBN tool because material became softening and deterioration by local laser beam irradiation. The advantage of LAM is the ability to produce larger material removal rates and tool life. But, for cutting of $Al_2O_3$ and $ZrO_2$, stage of laser power control was needed owing to thermal shock with high temperature of workpiece by laser power. And when $Si_3N_4$ was machined by LAM, $N_2$ gas spouted from surface of one cause of high temperature. Characteristics of LAM were analyzed using pyrometer, dynamometer, SEM and EDS to measure temperature of workpiece surface, cutting force, variation of machining surface and structure of lattice respectively. As the result of this study, it was found that machinability of LAM for ceramics in $CO_2$ laser and mechanism of LAM was different according to the kind of ceramics because of properties of materials.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1996년도 하계학술대회 논문집 A
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• pp.514-517
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• 1996

Zero current switching(ZCS) series resonant converter is used to control laser power density in a pulsed Nd:YAG laser power supply. The high power and high repetition rate paused Nd:YAG laser is designed and fabricated to control current pulse width and pulse repetition rate in the double elliptical laser oscillator. In order to find out operational characteristics of pulsed Nd:YAG laser, the electrical properties of driving power supply and laser output power are investigated and experimented by changing of the current pulse width from 200uS to 350uS(step 50uS) and pulse repetition rate range of 500pps(pulse per second) to 1150pps. From that result, we obtaind maximum efficiency of 1.83% and maximum laser output or 220W at the condition of 350 uS and 1150pps with one Nd:YAG rod), and obtained that of more than 400W with two laser head connecting series.

• 대한소아치과학회지
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• 제24권1호
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• pp.139-147
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• 1997

Argon laser used in this case report, is special in having two wavelength of 488, 514nm blue-green visible light spectrum. Blue light is used for composite resin polymerization and caries detection. Green light is used for soft tissue surgery and coagulation. Maximum absorption of this laser light occurs in red pigmentation such as hemoglobin. The argon laser may be well-suited for selective destruction of blood clots and hemangioma with minimal damage to adjacent tissues. Argon laser light penetrates tissue to the 1 mm depth, so its thermal intensity is lower than $CO_2$ laser light. Also, due to its short wavelength it can be focused in a small spot and even single gene can be excised by this laser and microscopy. After applicating argon laser to 4 patient for surgical procedure and to 1 patient for curing the composite resin, following results were obtained. 1. Improved visibility were gained due to hemostasis and no specific technique were needed according to easy recontouring of the tissue. 2. Ability to use by contact mode, tactile sense was superior but tissue dragability and accumulation of tissue on the tip needed sweeping motion. 3. Additive local anesthetic procedure was needed. 4. No suture and less curing time reduced chair time, this made argon laser available in pediatric dentistry.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 추계학술대회
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• pp.910-915
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• 2004

The objective of this study is to investigate the influence of process parameters, such as power of laser, travel speed of laser and material thickness, on the practical cutting region and the kerfwidth for the case of cutting of CSP 1N sheet using high power Nd:YAG laser with continuous wave(CW). In order to find the practical cutting region and the relationship between process parameters on the kerfwidth, several laser cutting experiments are carried out. The effective heat input is introduced to consider the influence of power and travel speed of laser on the kerfwidth together. From the results of experiments, the allowable cutting region and the relationship between the effective heat input and kerfwidth for the case of cutting of CSP 1N sheet using high power CW Nd:YAG laser have been obtained to improve the dimensional accuracy of the cut area.

• 대한기계학회논문집B
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• 제22권8호
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• pp.1073-1082
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• 1998

When thermal diffusivity is measured by laser flash method, the thermal diffusivity call be calculated front the assumption of the uniformly heated whole surface of the specimen. It has been known that the approximate 5% error is made by the non-uniform energy distribution on the specimen surface of laser pulse heat source. In this study, to obtain the highly-uniformed laser beam, which has both the low non-uniform heating error from non-uniform laser beam and the energy loss, research was carried out on no transmitting loss by optical fiber and high repetitions. In addition, heating error and thermal diffusivity were measured as the measuring positions were varied and compared with the results using the uniform and the non-uniform laser beams. In addition, dole to using the uniformalized laser beam, the whole surface of the specimen was heated uniformly and as a result, it was the thought that this was very effective to reduce the variations of the errors of the thermal diffusivity as the measuring positions were varied. It can be obtained that when the thermal diffusivity of POCO-AXM-5Q1 of SRM in NBS was measured with both the uniform and the non-uniform laser beams, the dispersion error of the former was from 2 to 2.5%, which was more improved than that of the latter.